Published in J Neurooncol on January 13, 2010
Current review of in vivo GBM rodent models: emphasis on the CNS-1 tumour model. ASN Neuro (2011) 1.44
Stereotactic intracranial implantation and in vivo bioluminescent imaging of tumor xenografts in a mouse model system of glioblastoma multiforme. J Vis Exp (2012) 1.17
The ketogenic diet and hyperbaric oxygen therapy prolong survival in mice with systemic metastatic cancer. PLoS One (2013) 1.02
Ketone supplementation decreases tumor cell viability and prolongs survival of mice with metastatic cancer. Int J Cancer (2014) 1.01
Hypothesis: are neoplastic macrophages/microglia present in glioblastoma multiforme? ASN Neuro (2011) 1.00
Gene therapy for brain tumors: basic developments and clinical implementation. Neurosci Lett (2012) 0.98
On the origin of cancer metastasis. Crit Rev Oncog (2013) 0.97
Non-Toxic Metabolic Management of Metastatic Cancer in VM Mice: Novel Combination of Ketogenic Diet, Ketone Supplementation, and Hyperbaric Oxygen Therapy. PLoS One (2015) 0.95
Differential microstructure and physiology of brain and bone metastases in a rat breast cancer model by diffusion and dynamic contrast enhanced MRI. Clin Exp Metastasis (2011) 0.92
Immunocompetent murine models for the study of glioblastoma immunotherapy. J Transl Med (2014) 0.92
Influence of caloric restriction on constitutive expression of NF-κB in an experimental mouse astrocytoma. PLoS One (2011) 0.91
Calorie restriction as an anti-invasive therapy for malignant brain cancer in the VM mouse. ASN Neuro (2010) 0.90
Antiangiogenic therapy for glioma. J Signal Transduct (2012) 0.89
Perspectives on the mesenchymal origin of metastatic cancer. Cancer Metastasis Rev (2010) 0.86
Press-pulse: a novel therapeutic strategy for the metabolic management of cancer. Nutr Metab (Lond) (2017) 0.85
Computational Trials: Unraveling Motility Phenotypes, Progression Patterns, and Treatment Options for Glioblastoma Multiforme. PLoS One (2016) 0.83
Stemness of the CT-2A Immunocompetent Mouse Brain Tumor Model: Characterization In Vitro. J Cancer (2012) 0.80
IGF-Binding Protein 2 - Oncogene or Tumor Suppressor? Front Endocrinol (Lausanne) (2015) 0.79
Efficient photodynamic therapy on human retinoblastoma cell lines. PLoS One (2014) 0.75
Key rates for the grades and transformation ability of glioma: model simulations and clinical cases. J Neurooncol (2017) 0.75
Stem cells act through multiple mechanisms to benefit mice with neurodegenerative metabolic disease. Nat Med (2007) 2.57
Structural insights into the U-box, a domain associated with multi-ubiquitination. Nat Struct Biol (2003) 2.26
The calorically restricted ketogenic diet, an effective alternative therapy for malignant brain cancer. Nutr Metab (Lond) (2007) 1.75
Metabolic management of glioblastoma multiforme using standard therapy together with a restricted ketogenic diet: Case Report. Nutr Metab (Lond) (2010) 1.46
Cardiolipin and electron transport chain abnormalities in mouse brain tumor mitochondria: lipidomic evidence supporting the Warburg theory of cancer. J Lipid Res (2008) 1.44
Structural and functional analysis of essential pre-mRNA splicing factor Prp19p. Mol Cell Biol (2005) 1.42
Targeting energy metabolism in brain cancer: review and hypothesis. Nutr Metab (Lond) (2005) 1.40
The Prp19 U-box crystal structure suggests a common dimeric architecture for a class of oligomeric E3 ubiquitin ligases. Biochemistry (2006) 1.38
Antiangiogenic and proapoptotic effects of dietary restriction on experimental mouse and human brain tumors. Clin Cancer Res (2004) 1.37
Perspectives on the metabolic management of epilepsy through dietary reduction of glucose and elevation of ketone bodies. J Neurochem (2003) 1.36
Pericyte deficiencies lead to aberrant tumor vascularizaton in the brain of the NG2 null mouse. Dev Biol (2010) 1.34
Lipidomic analysis and electron transport chain activities in C57BL/6J mouse brain mitochondria. J Neurochem (2008) 1.29
Management of multifactorial idiopathic epilepsy in EL mice with caloric restriction and the ketogenic diet: role of glucose and ketone bodies. Nutr Metab (Lond) (2004) 1.22
Up-regulation of NG2 proteoglycan and interferon-induced transmembrane proteins 1 and 3 in mouse astrocytoma: a membrane proteomics approach. Cancer Lett (2008) 1.22
A single intravenous rAAV injection as late as P20 achieves efficacious and sustained CNS Gene therapy in Canavan mice. Mol Ther (2013) 1.19
Metastatic cancer cells with macrophage properties: evidence from a new murine tumor model. Int J Cancer (2008) 1.13
HIV-1 phylogenetic analysis shows HIV-1 transits through the meninges to brain and peripheral tissues. Infect Genet Evol (2010) 1.12
Caloric restriction in C57BL/6J mice mimics therapeutic fasting in humans. Lipids Health Dis (2006) 1.12
Differentiating N-linked glycan structural isomers in metastatic and nonmetastatic tumor cells using sequential mass spectrometry. Glycobiology (2008) 1.11
Metabolic management of brain cancer. Biochim Biophys Acta (2010) 1.09
Drug/diet synergy for managing malignant astrocytoma in mice: 2-deoxy-D-glucose and the restricted ketogenic diet. Nutr Metab (Lond) (2008) 1.07
Itaconic acid is a mammalian metabolite induced during macrophage activation. J Am Chem Soc (2011) 1.06
Dynamic simulation of cardiolipin remodeling: greasing the wheels for an interpretative approach to lipidomics. J Lipid Res (2010) 1.05
Differential effects of energy stress on AMPK phosphorylation and apoptosis in experimental brain tumor and normal brain. Mol Cancer (2008) 1.04
Akt-dependent proapoptotic effects of dietary restriction on late-stage management of a phosphatase and tensin homologue/tuberous sclerosis complex 2-deficient mouse astrocytoma. Clin Cancer Res (2008) 1.04
Targeting energy metabolism in brain cancer through calorie restriction and the ketogenic diet. J Cancer Res Ther (2009) 1.03
The ketogenic diet and hyperbaric oxygen therapy prolong survival in mice with systemic metastatic cancer. PLoS One (2013) 1.02
Hypothesis: are neoplastic macrophages/microglia present in glioblastoma multiforme? ASN Neuro (2011) 1.00
Targeting energy metabolism in brain cancer with calorically restricted ketogenic diets. Epilepsia (2008) 0.98
On the origin of cancer metastasis. Crit Rev Oncog (2013) 0.97
Therapeutic response in feline sandhoff disease despite immunity to intracranial gene therapy. Mol Ther (2013) 0.97
Distinct patterns of HIV-1 evolution within metastatic tissues in patients with non-Hodgkins lymphoma. PLoS One (2009) 0.97
AAV-mediated gene delivery in adult GM1-gangliosidosis mice corrects lysosomal storage in CNS and improves survival. PLoS One (2010) 0.96
Glutamine targeting inhibits systemic metastasis in the VM-M3 murine tumor model. Int J Cancer (2010) 0.95
Glucose-dependent de novo lipogenesis in B lymphocytes: a requirement for atp-citrate lyase in lipopolysaccharide-induced differentiation. J Biol Chem (2014) 0.95
N-butyldeoxygalactonojirimycin reduces neonatal brain ganglioside content in a mouse model of GM1 gangliosidosis. J Neurochem (2004) 0.94
Neurochemical, morphological, and neurophysiological abnormalities in retinas of Sandhoff and GM1 gangliosidosis mice. J Neurochem (2007) 0.94
Sexual dysfunction and sudden death in epileptic male EL mice: inheritance and prevention with the ketogenic diet. Epilepsia (2003) 0.93
Glycolipid and ganglioside metabolism imbalances in Huntington's disease. Neurobiol Dis (2007) 0.93
Influence of caloric restriction on motor behavior, longevity, and brain lipid composition in Sandhoff disease mice. J Neurosci Res (2006) 0.93
N-butyldeoxygalactonojirimycin reduces brain ganglioside and GM2 content in neonatal Sandhoff disease mice. Neurochem Int (2007) 0.92
Inheritance of lysosomal acid beta-galactosidase activity and gangliosides in crosses of DBA/2J and knockout mice. Biochem Genet (2004) 0.92
Thematic review series: sphingolipids. Ganglioside GM3 suppresses the proangiogenic effects of vascular endothelial growth factor and ganglioside GD1a. J Lipid Res (2008) 0.92
Is the restricted ketogenic diet a viable alternative to the standard of care for managing malignant brain cancer? Epilepsy Res (2011) 0.92
Oxygenation prevents sudden death in seizure-prone mice. Epilepsia (2004) 0.91
Influence of caloric restriction on constitutive expression of NF-κB in an experimental mouse astrocytoma. PLoS One (2011) 0.91
Filipin recognizes both GM1 and cholesterol in GM1 gangliosidosis mouse brain. J Lipid Res (2011) 0.90
Hippocampal neurons and glia in epileptic EL mice. J Neurocytol (2003) 0.90
Calorie restriction as an anti-invasive therapy for malignant brain cancer in the VM mouse. ASN Neuro (2010) 0.90
Influence of methotrexate and cisplatin on tumor progression and survival in the VM mouse model of systemic metastatic cancer. Int J Cancer (2010) 0.89
Comparative analysis of brain lipids in mice, cats, and humans with Sandhoff disease. Lipids (2008) 0.88
Examination of the brain mitochondrial lipidome using shotgun lipidomics. Methods Mol Biol (2009) 0.87
HIV-1 Nef in macrophage-mediated disease pathogenesis. Int Rev Immunol (2012) 0.86
In vitro growth environment produces lipidomic and electron transport chain abnormalities in mitochondria from non-tumorigenic astrocytes and brain tumours. ASN Neuro (2009) 0.86
Brain mitochondrial lipid abnormalities in mice susceptible to spontaneous gliomas. Lipids (2008) 0.86
Perspectives on the mesenchymal origin of metastatic cancer. Cancer Metastasis Rev (2010) 0.86
Improvement in motor and exploratory behavior in Rett syndrome mice with restricted ketogenic and standard diets. Epilepsy Behav (2009) 0.86
Absence of pathogenic mitochondrial DNA mutations in mouse brain tumors. BMC Cancer (2005) 0.85
Gene-linked shift in ganglioside distribution influences growth and vascularity in a mouse astrocytoma. J Neurochem (2006) 0.85
Does the existing standard of care increase glioblastoma energy metabolism? Lancet Oncol (2010) 0.84
Cerebellar lipid differences between R6/1 transgenic mice and humans with Huntington's disease. J Neurochem (2010) 0.82
A mathematical model for the determination of steady-state cardiolipin remodeling mechanisms using lipidomic data. PLoS One (2011) 0.82
Ganglioside GM3 Is Antiangiogenic in Malignant Brain Cancer. J Oncol (2010) 0.81
Ethylenedioxy-PIP2 oxalate reduces ganglioside storage in juvenile Sandhoff disease mice. Neurochem Res (2013) 0.80
Dietary restriction promotes vessel maturation in a mouse astrocytoma. J Oncol (2011) 0.80
The EL mouse: a natural model of autism and epilepsy. Epilepsia (2011) 0.80
Trametes versicolor extract modifies human fecal microbiota composition in vitro. Plant Foods Hum Nutr (2013) 0.79
HIV-1 nef protein visits B-cells via macrophage nanotubes: a mechanism for AIDS-related lymphoma pathogenesis? Curr HIV Res (2010) 0.79
Lipid composition of whole brain and cerebellum in Hurler syndrome (MPS IH) mice. Neurochem Res (2011) 0.79
Peripheral nervous system manifestations in a Sandhoff disease mouse model: nerve conduction, myelin structure, lipid analysis. J Negat Results Biomed (2007) 0.79
Autosomal dominant inheritance of brain cardiolipin fatty acid abnormality in VM/DK mice: association with hypoxic-induced cognitive insensitivity. Lipids (2013) 0.78
Restricted ketogenic diet enhances the therapeutic action of N-butyldeoxynojirimycin towards brain GM2 accumulation in adult Sandhoff disease mice. J Neurochem (2010) 0.77
Bis(monoacylglycero)phosphate as a Macrophage Enriched Phospholipid. Lipids (2015) 0.76
Behavioral seizure correlates in animal models of epilepsy: a road map for assay selection, data interpretation, and the search for causal mechanisms. Epilepsy Behav (2006) 0.75