J P Dougherty

Author PubWeight™ 57.55‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 High mutation rate of a spleen necrosis virus-based retrovirus vector. Mol Cell Biol 1986 3.57
2 High rate of recombination throughout the human immunodeficiency virus type 1 genome. J Virol 2000 3.09
3 The thermal stability of oligonucleotide duplexes is sequence independent in tetraalkylammonium salt solutions: application to identifying recombinant DNA clones. Nucleic Acids Res 1988 2.95
4 Stimulation of in vitro transcription from heterologous promoters by the simian virus 40 enhancer. Proc Natl Acad Sci U S A 1984 2.44
5 A promoterless retroviral vector indicates that there are sequences in U3 required for 3' RNA processing. Proc Natl Acad Sci U S A 1987 2.13
6 Mechanisms of retroviral mutation. Trends Microbiol 1996 1.85
7 Comparison of Moloney murine leukemia virus mutation rate with the fidelity of its reverse transcriptase in vitro. J Biol Chem 1992 1.73
8 A gene therapy approach for treating T-cell-mediated autoimmune diseases. Blood 2001 1.69
9 Genetic rearrangements occurring during a single cycle of murine leukemia virus vector replication: characterization and implications. J Virol 1995 1.62
10 Immobilization of DNA via oligonucleotides containing an aldehyde or carboxylic acid group at the 5' terminus. Nucleic Acids Res 1987 1.55
11 The nature of human immunodeficiency virus type 1 strand transfers. J Biol Chem 1998 1.52
12 Inducible human immunodeficiency virus type 1 packaging cell lines. J Virol 1996 1.49
13 Isolation of a cDNA clone encoding a high molecular weight precursor to a 6-kDa pulmonary surfactant-associated protein. J Biol Chem 1987 1.40
14 Role of B cells as antigen-presenting cells in vivo revisited: antigen-specific B cells are essential for T cell expansion in lymph nodes and for systemic T cell responses to low antigen concentrations. Int Immunol 2001 1.36
15 Interferon, double-stranded RNA, and RNA degradation. Isolation of homogeneous pppA(2'p5'A)n-1 synthetase from Ehrlich ascites tumor cells. J Biol Chem 1980 1.30
16 In vivo analysis of a new lacZ retrovirus vector suitable for cell lineage marking in avian and other species. Exp Cell Res 1991 1.24
17 Both anti-CD11a (LFA-1) and anti-CD11b (MAC-1) therapy delay the onset and diminish the severity of experimental autoimmune encephalomyelitis. J Neuroimmunol 1995 1.23
18 High rate of genetic rearrangement during replication of a Moloney murine leukemia virus-based vector. J Virol 1993 1.21
19 Mutations of conserved cysteine residues in the CWLC motif of the oncoretrovirus SU protein affect maturation and translocation. Virology 1995 1.17
20 Rapid hybridization kinetics of DNA attached to submicron latex particles. Nucleic Acids Res 1987 1.13
21 Spleen necrosis virus, an avian retrovirus, can infect primate cells. J Virol 1991 1.05
22 Synergy between encephalitogenic T cells and myelin basic protein-specific antibodies in the induction of experimental autoimmune encephalomyelitis. J Neuroimmunol 1992 1.04
23 A nickel chelate microtiter plate assay for six histidine-containing proteins. Anal Biochem 1996 1.00
24 Reticuloendotheliosis type C and primate type D oncoretroviruses are members of the same receptor interference group. J Virol 1992 0.99
25 Synthesis of (2'-5')(A)n from ATP. Characteristics of the reaction catalyzed by (2'-5')(A)n synthetase purified from mouse Ehrlich ascites tumor cells treated with interferon. J Biol Chem 1980 0.96
26 An inducible packaging cell system for safe, efficient lentiviral vector production in the absence of HIV-1 accessory proteins. Virology 2001 0.95
27 In vivo antigen presentation by both brain parenchymal cells and hematopoietically derived cells during the induction of experimental autoimmune encephalomyelitis. J Immunol 1993 0.93
28 Reaction mechanism of Ca2+-dependent ATP hydrolysis by skeletal muscle sarcoplasmic reticulum in the absence of added alkali metal salts. II. Kinetic properties of the phosphoenzyme formed at the steady state in high Mg2+ and low Ca2+ concentrations. J Biol Chem 1978 0.92
29 Inhibition of Ly-6A antigen expression prevents T cell activation. J Exp Med 1990 0.92
30 Discontinuous plus-strand DNA synthesis in human immunodeficiency virus type 1-infected cells and in a partially reconstituted cell-free system. J Virol 1997 0.92
31 Reaction mechanism of Ca2+-dependent ATP hydrolysis by skeletal muscle sarcoplasmic reticulum in the absence of added alkali metal salts. I. Characterization of steady state ATP hydrolysis and comparison with that in the presence of KCl. J Biol Chem 1978 0.91
32 A spleen necrosis virus-based retroviral vector which expresses two genes from a dicistronic mRNA. Virology 1992 0.90
33 Pseudotyped REV/SRV retroviruses reveal restrictions to infection and host range within members of the same receptor interference group. Virology 1994 0.87
34 The effect of febrile temperatures on biologic actions of interferons: abrogation of suppression of delayed-type hypersensitivity and antibody production. J Immunol 1984 0.87
35 Transduction of cellular sequence by a human immunodeficiency virus type 1-derived vector. J Virol 2001 0.86
36 The mouse immunoglobulin heavy-chain gene enhancer contains sequences that inhibit transcription in vitro in HeLa cell extracts. Mol Cell Biol 1986 0.84
37 A murine model for B-lymphocyte somatic cell gene therapy. Proc Natl Acad Sci U S A 1994 0.83
38 N2- and C8-substituted oligodeoxynucleotides with enhanced thrombin inhibitory activity in vitro and in vivo. J Med Chem 1998 0.83
39 Regulated lentiviral packaging cell line devoid of most viral cis-acting sequences. Virology 1998 0.83
40 Use of single-cycle analysis to study rates and mechanisms of retroviral mutation. Methods 1997 0.82
41 Reaction mechanism of Ca2+-dependent ATP hydrolysis by skeletal muscle sarcoplasmic reticulum in the absence of added alkali metal salts. III. Sequential occurrence of ADP-sensitive and ADP-insensitive phosphoenzymes. J Biol Chem 1978 0.82
42 Studies with pure mouse Ehrlich ascites tumor interferons alpha and beta: patterns of induction of (2'-5') (A)n synthetase and of a double-stranded RNA-dependent protein kinase in mouse cells and human cells. J Interferon Res 1981 0.82
43 Determination of retroviral mutation rates using spleen necrosis virus-based vectors and helper cells. Biotechnology 1991 0.81
44 Efficient gene transfer into primary murine lymphocytes obviating the need for drug selection. Blood 1993 0.76
45 Antisense translates into sense. J Exp Med 1999 0.75
46 Single-Crystal Raman Evidence for and X-Ray Analysis of the Distorted Square-Pyramidal Pentachlorothallate and Pentachloroindate Complexes in [(C(2)H(5))(4)N](2)[TlCl(5)] and [(C(2)H(5))(4)N](2)[InCl(5)]. Inorg Chem 1975 0.75
47 Long-term contribution to the myeloid compartment by lineage-committed stem cells. Blood 1998 0.75
48 A murine model for genetic manipulation of the T cell compartment. Exp Hematol 1996 0.75
49 Instrumentation for Zeeman electrothermal atomizer laser excited atomic fluorescence spectrometry. Anal Chem 1987 0.75
50 Laser-excited atomic fluorescence spectrometry with a laboratory-constructed tube electrothermal atomizer. Anal Chem 1987 0.75
51 Some kinetic properties of phosphorylated ATPase of sarcoplasmic reticulum formed in the absence of added alkali metal salts. Biochem Biophys Res Commun 1977 0.75
52 Computer resources for student use at US colleges of pharmacy. Ann Pharmacother 1994 0.75
53 Determination of thallium in bovine liver and mouse brains by laser excited atomic fluorescence spectrometry in a graphite tube furnace. Anal Chem 1988 0.75
54 A peripheral blood-derived monolayer supports long-term cultures of human CD4+ and CD8+ T lymphocytes. Blood 1995 0.75
55 Enzymology of interferon action. The (2'-5')(A)n synthetase-RNase L pathway. Tex Rep Biol Med 1983 0.75