Published in Proc Natl Acad Sci U S A on January 01, 1984
Multiple sequence motifs are involved in SV40 enhancer function. EMBO J (1986) 7.76
Stimulation of in vitro transcription from the SV40 early promoter by the enhancer involves a specific trans-acting factor. EMBO J (1984) 4.28
Interactions of cellular proteins involved in the transcriptional regulation of the human immunodeficiency virus. EMBO J (1987) 4.14
Six distinct nuclear factors interact with the 75-base-pair repeat of the Moloney murine leukemia virus enhancer. Mol Cell Biol (1987) 4.02
OVEC, a versatile system to study transcription in mammalian cells and cell-free extracts. Nucleic Acids Res (1987) 3.56
A cellular transcription factor E4F1 interacts with an E1a-inducible enhancer and mediates constitutive enhancer function in vitro. EMBO J (1987) 3.45
Specific interaction of cellular factors with the B enhancer of polyoma virus. EMBO J (1985) 3.23
Specific interaction between a transcription factor and the upstream element of the adenovirus-2 major late promoter. EMBO J (1985) 2.83
Specific protein binding to the simian virus 40 enhancer in vitro. Mol Cell Biol (1986) 2.82
Effects of the position of the simian virus 40 enhancer on expression of multiple transcription units in a single plasmid. Mol Cell Biol (1986) 2.73
Cell type-specific transcriptional enhancement in vitro requires the presence of trans-acting factors. EMBO J (1985) 2.70
Hormonal response region in the mouse mammary tumor virus long terminal repeat can be dissociated from the proviral promoter and has enhancer properties. Proc Natl Acad Sci U S A (1985) 2.47
Short and long range activation by the SV40 enhancer. Nucleic Acids Res (1984) 2.35
Stimulation of in vitro transcription by the upstream element of the adenovirus-2 major late promoter involves a specific factor. Nucleic Acids Res (1984) 2.31
Determination of the promoter region of mouse ribosomal RNA gene by an in vitro transcription system. Proc Natl Acad Sci U S A (1984) 2.18
Transcriptional analysis of the adenovirus-5 EIII promoter: absence of sequence specificity for stimulation by EIa gene products. Nucleic Acids Res (1985) 2.04
One cell-specific and three ubiquitous nuclear proteins bind in vitro to overlapping motifs in the domain B1 of the SV40 enhancer. EMBO J (1987) 2.04
Effect of the 21-bp repeat upstream element on in vitro transcription from the early and late SV40 promoters. EMBO J (1984) 2.03
The mouse immunoglobulin heavy-chain enhancer: effect on transcription in vitro and binding of proteins present in HeLa and lymphoid B cell extracts. EMBO J (1986) 1.95
At least two nuclear proteins bind specifically to the Rous sarcoma virus long terminal repeat enhancer. Mol Cell Biol (1987) 1.74
Simian virus 40 guanine-cytosine-rich sequences function as independent transcriptional control elements in vitro. Mol Cell Biol (1984) 1.52
Analysis of gene expression in mouse preimplantation embryos demonstrates that the primary role of enhancers is to relieve repression of promoters. EMBO J (1993) 1.19
A single regulatory region modulates both cis activation and trans activation of the herpes simplex virus VP5 promoter in transient-expression assays in vivo. J Virol (1986) 1.18
Interactions between nuclear factors and the hepatitis B virus enhancer. J Virol (1989) 1.16
Organization of the transcriptional control region of the E1b gene of adenovirus type 5. J Virol (1988) 1.08
Tissue-specific transcription enhancement of the fibroin gene characterized by cell-free systems. Proc Natl Acad Sci U S A (1986) 1.07
Goals for signal transduction pathways: linking up with transcriptional regulation. EMBO J (1994) 1.03
Functional activity and chromatin configuration of SV40 enhancer injected in Xenopus laevis oocytes. Nucleic Acids Res (1985) 1.01
The SV40 enhancer influences viral late transcription in vitro and in vivo but not on replicating templates. EMBO J (1985) 1.00
Sequences involved in initiation of simian virus 40 late transcription in the absence of T antigen. Mol Cell Biol (1986) 0.97
The Drosophila even-skipped promoter is transcribed in a stage-specific manner in vitro and contains multiple, overlapping factor-binding sites. Mol Cell Biol (1990) 0.96
In vitro transcription of immunoglobulin genes in a B-cell extract: effects of enhancer and promoter sequences. Mol Cell Biol (1987) 0.96
The chicken delta 1-crystallin gene promoter: binding of transcription factor(s) to the upstream G+C-rich region is necessary for promoter function in vitro. Proc Natl Acad Sci U S A (1986) 0.93
The regulation of SV40 early gene expression in embryonal carcinoma stem cells--faithful transcriptional regulation in vitro. Nucleic Acids Res (1988) 0.91
Stereospecific relationships between elements in an SV40/adenovirus-2 heterologous promoter. Nucleic Acids Res (1989) 0.87
The mouse immunoglobulin heavy-chain gene enhancer contains sequences that inhibit transcription in vitro in HeLa cell extracts. Mol Cell Biol (1986) 0.84
Optimizing gene expression in BPV-transformed cells: effects of cell type on enhancer/promoter interaction. Nucleic Acids Res (1987) 0.77
Sequencing end-labeled DNA with base-specific chemical cleavages. Methods Enzymol (1980) 287.68
Organization and expression of eucaryotic split genes coding for proteins. Annu Rev Biochem (1981) 49.46
SV40-transformed simian cells support the replication of early SV40 mutants. Cell (1981) 34.67
Transcriptional control signals of a eukaryotic protein-coding gene. Science (1982) 25.38
In vivo sequence requirements of the SV40 early promotor region. Nature (1981) 25.00
DNA-dependent transcription of adenovirus genes in a soluble whole-cell extract. Proc Natl Acad Sci U S A (1980) 24.21
Expression of a beta-globin gene is enhanced by remote SV40 DNA sequences. Cell (1981) 20.72
A lymphocyte-specific cellular enhancer is located downstream of the joining region in immunoglobulin heavy chain genes. Cell (1983) 20.32
Promoter sequences of eukaryotic protein-coding genes. Science (1980) 19.96
A tissue-specific transcription enhancer element is located in the major intron of a rearranged immunoglobulin heavy chain gene. Cell (1983) 18.86
Immunoglobulin gene transcription is activated by downstream sequence elements. Cell (1983) 15.53
The SV40 72 base repair repeat has a striking effect on gene expression both in SV40 and other chimeric recombinants. Nucleic Acids Res (1981) 15.12
A regulatory upstream promoter element in the Drosophila hsp 70 heat-shock gene. Cell (1982) 14.32
Simian virus 40 tandem repeated sequences as an element of the early promoter. Proc Natl Acad Sci U S A (1981) 13.67
Faithful transcription of eukaryotic genes by RNA polymerase III in systems reconstituted with purified DNA templates. J Biol Chem (1979) 11.68
Deletion mapping of DNA regions required for SV40 early region promoter function in vivo. J Mol Appl Genet (1982) 10.71
Enhancer elements. Cell (1983) 10.41
Identification of DNA sequences required for transcription of the human alpha 1-globin gene in a new SV40 host-vector system. Cell (1981) 9.81
Three regions upstream from the cap site are required for efficient and accurate transcription of the rabbit beta-globin gene in mouse 3T6 cells. Cell (1983) 9.51
Isolation of transcription factors that discriminate between different promoters recognized by RNA polymerase II. Cell (1983) 8.85
DNA sequences bound specifically by glucocorticoid receptor in vitro render a heterologous promoter hormone responsive in vivo. Cell (1983) 7.39
Formation of stable preinitiation complexes between eukaryotic class B transcription factors and promoter sequences. Nature (1983) 7.22
The organization and expression of histone gene families. Cell (1981) 6.66
Nucleotide sequences from the adenovirus-2 genome. J Biol Chem (1982) 5.76
The SV40 72 bp repeat preferentially potentiates transcription starting from proximal natural or substitute promoter elements. Cell (1983) 5.67
The repeated GC-rich motifs upstream from the TATA box are important elements of the SV40 early promoter. Nucleic Acids Res (1983) 4.93
Sequences upstream from the T-A-T-A box are required in vivo and in vitro for efficient transcription from the adenovirus serotype 2 major late promoter. Proc Natl Acad Sci U S A (1982) 4.30
Delimitation of far upstream sequences required for maximal in vitro transcription of an H2A histone gene. Proc Natl Acad Sci U S A (1982) 2.90
Transcriptional control regions: nucleotide sequence requirements for initiation by RNA polymerase II and III. Curr Top Microbiol Immunol (1981) 2.85
Promotion of specific in vitro transcription by excised "TATA" box sequences inserted in a foreign nucleotide environment. Nucleic Acids Res (1981) 2.57
Transcription from the SV40 early-early and late-early overlapping promoters in the absence of DNA replication. EMBO J (1983) 2.55
Simian virus 40 early- and late-region promoter functions are enhanced by the 72-base-pair repeat inserted at distant locations and inverted orientations. Mol Cell Biol (1983) 2.53
Transcription in vivo from SV40 early promoter deletion mutants without repression by large T antigen. J Mol Appl Genet (1983) 2.48
SV40 T antigen binding site mutations that affect autoregulation. Cell (1983) 2.43
Faithful transcription initiation of fibroin gene in a homologous cell-free system reveals an enhancing effect of 5' flanking sequence far upstream. Cell (1981) 2.42
Analysis of the transcriptional enhancer effect. Cold Spring Harb Symp Quant Biol (1983) 1.99
Enhancing elements for activation of eukaryotic promoters. Nature (1982) 1.74
Enhancer elements in immunoglobulin genes. Nature (1983) 1.05
Protein contacts for promoter location in eukaryotes. Nature (1983) 1.00
Sequence requirement for transcription in vitro of the human corticotropin/beta-lipotropin precursor gene. Eur J Biochem (1983) 0.83
Organization and expression of eucaryotic split genes coding for proteins. Annu Rev Biochem (1981) 49.46
In vivo sequence requirements of the SV40 early promotor region. Nature (1981) 25.00
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Isolation of high-molecular-weight DNA from mammalian cells. Eur J Biochem (1973) 24.38
Promoter sequences of eukaryotic protein-coding genes. Science (1980) 19.96
The ovalbumin gene-sequence of putative control regions. Nucleic Acids Res (1980) 18.04
A reliable method for the recovery of DNA fragments from agarose and acrylamide gels. Anal Biochem (1981) 15.38
The SV40 72 base repair repeat has a striking effect on gene expression both in SV40 and other chimeric recombinants. Nucleic Acids Res (1981) 15.12
Ovalbumin gene: evidence for a leader sequence in mRNA and DNA sequences at the exon-intron boundaries. Proc Natl Acad Sci U S A (1978) 14.82
Human oestrogen receptor cDNA: sequence, expression and homology to v-erb-A. Nature (1986) 11.35
Specific in vitro transcription of conalbumin gene is drastically decreased by single-point mutation in T-A-T-A box homology sequence. Proc Natl Acad Sci U S A (1980) 10.27
Specific in vitro initiation of transcription on conalbumin and ovalbumin genes and comparison with adenovirus-2 early and late genes. Nature (1980) 10.22
DNA repair helicase: a component of BTF2 (TFIIH) basic transcription factor. Science (1993) 9.94
Folding of the DNA double helix in chromatin-like structures from simian virus 40. Proc Natl Acad Sci U S A (1975) 9.70
Organisation and sequences at the 5' end of a cloned complete ovalbumin gene. Nature (1979) 9.30
A human retinoic acid receptor which belongs to the family of nuclear receptors. Nature (1988) 9.07
Electron microscopic and biochemical evidence that chromatin structure is a repeating unit. Cell (1975) 8.90
Regulation of Cre recombinase activity by mutated estrogen receptor ligand-binding domains. Biochem Biophys Res Commun (1997) 7.87
Deletions covering the putative promoter region of early mRNAs of simian virus 40 do not abolish T-antigen expression. Proc Natl Acad Sci U S A (1980) 7.77
Multiple sequence motifs are involved in SV40 enhancer function. EMBO J (1986) 7.76
Formation of stable preinitiation complexes between eukaryotic class B transcription factors and promoter sequences. Nature (1983) 7.22
Adenovirus-2 E1A products repress enhancer-induced stimulation of transcription. Nature (1985) 7.14
Ovalbumin gene is split in chicken DNA. Nature (1977) 7.05
The estrogen receptor binds tightly to its responsive element as a ligand-induced homodimer. Cell (1988) 6.59
Functional domains of the human estrogen receptor. Cell (1987) 6.52
Ligand-activated site-specific recombination in mice. Proc Natl Acad Sci U S A (1996) 6.48
Activation of the estrogen receptor through phosphorylation by mitogen-activated protein kinase. Science (1995) 6.37
Temporally-controlled site-specific mutagenesis in the basal layer of the epidermis: comparison of the recombinase activity of the tamoxifen-inducible Cre-ER(T) and Cre-ER(T2) recombinases. Nucleic Acids Res (1999) 6.35
The human estrogen receptor has two independent nonacidic transcriptional activation functions. Cell (1989) 6.24
A Brg1 null mutation in the mouse reveals functional differences among mammalian SWI/SNF complexes. Mol Cell (2000) 6.14
Localisation of the oestradiol-binding and putative DNA-binding domains of the human oestrogen receptor. EMBO J (1986) 6.08
Nuclear receptors enhance our understanding of transcription regulation. Trends Genet (1988) 5.95
Synergistic coupling of histone H3 phosphorylation and acetylation in response to epidermal growth factor stimulation. Mol Cell (2000) 5.79
The SV40 72 bp repeat preferentially potentiates transcription starting from proximal natural or substitute promoter elements. Cell (1983) 5.67
Gastric mucosa abnormalities and tumorigenesis in mice lacking the pS2 trefoil protein. Science (1996) 5.55
Oestradiol induction of a glucocorticoid-responsive gene by a chimaeric receptor. Nature (1987) 5.47
The SV40 early region TATA box is required for accurate in vitro initiation of transcription. Nature (1981) 5.43
Crystal structure of the ligand-binding domain of the human nuclear receptor RXR-alpha. Nature (1995) 5.40
Signaling to chromatin through histone modifications. Cell (2000) 5.36
Embryonic retinoic acid synthesis is essential for early mouse post-implantation development. Nat Genet (1999) 5.31
Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation. EMBO J (2001) 5.29
Requirement of poly(ADP-ribose) polymerase in recovery from DNA damage in mice and in cells. Proc Natl Acad Sci U S A (1997) 5.24
Induction of proto-oncogene JUN/AP-1 by serum and TPA. Nature (1988) 5.18
Cloning of cDNA sequences of hormone-regulated genes from the MCF-7 human breast cancer cell line. Nucleic Acids Res (1982) 5.14
A novel metalloproteinase gene specifically expressed in stromal cells of breast carcinomas. Nature (1991) 5.13
Identification of a second human retinoic acid receptor. Nature (1988) 5.11
Two distinct estrogen-regulated promoters generate transcripts encoding the two functionally different human progesterone receptor forms A and B. EMBO J (1990) 5.05
Effect of single and compound knockouts of estrogen receptors alpha (ERalpha) and beta (ERbeta) on mouse reproductive phenotypes. Development (2000) 5.03
Bidirectional SV40 transcription mediated by tandem Sp1 binding interactions. Science (1985) 5.00
TIF2, a 160 kDa transcriptional mediator for the ligand-dependent activation function AF-2 of nuclear receptors. EMBO J (1996) 4.96
The repeated GC-rich motifs upstream from the TATA box are important elements of the SV40 early promoter. Nucleic Acids Res (1983) 4.93
DNA methylation: organ specific variations in the methylation pattern within and around ovalbumin and other chicken genes. Nucleic Acids Res (1979) 4.81
Crystal structure of the RAR-gamma ligand-binding domain bound to all-trans retinoic acid. Nature (1995) 4.79
Requirement of stereospecific alignments for initiation from the simian virus 40 early promoter. Nature (1986) 4.77
The N-terminal part of TIF1, a putative mediator of the ligand-dependent activation function (AF-2) of nuclear receptors, is fused to B-raf in the oncogenic protein T18. EMBO J (1995) 4.72
A canonical structure for the ligand-binding domain of nuclear receptors. Nat Struct Biol (1996) 4.69
A possible involvement of TIF1 alpha and TIF1 beta in the epigenetic control of transcription by nuclear receptors. EMBO J (1996) 4.65
Nonsteroid nuclear receptors: what are genetic studies telling us about their role in real life? Cell (1995) 4.64
The chicken oestrogen receptor sequence: homology with v-erbA and the human oestrogen and glucocorticoid receptors. EMBO J (1986) 4.47
Organization and sequence studies of the 17-piece chicken conalbumin gene. Nature (1979) 4.36
Sequences upstream from the T-A-T-A box are required in vivo and in vitro for efficient transcription from the adenovirus serotype 2 major late promoter. Proc Natl Acad Sci U S A (1982) 4.30
Stimulation of in vitro transcription from the SV40 early promoter by the enhancer involves a specific trans-acting factor. EMBO J (1984) 4.28
The yeast UASG is a transcriptional enhancer in human HeLa cells in the presence of the GAL4 trans-activator. Cell (1988) 4.22
The hormone-binding domains of the estrogen and glucocorticoid receptors contain an inducible transcription activation function. Cell (1988) 4.17
Alpha-amanitin: a specific inhibitor of one of two DNA-pendent RNA polymerase activities from calf thymus. Biochem Biophys Res Commun (1970) 4.16
Characterization of the fasting-induced adipose factor FIAF, a novel peroxisome proliferator-activated receptor target gene. J Biol Chem (2000) 4.15
The ovalbumin gene family: structure of the X gene and evolution of duplicated split genes. Cell (1980) 4.14
CREM gene: use of alternative DNA-binding domains generates multiple antagonists of cAMP-induced transcription. Cell (1991) 4.11
Cooperativity and hierarchical levels of functional organization in the SV40 enhancer. Cell (1988) 4.03
A trans-acting factor is responsible for the simian virus 40 enhancer activity in vitro. Nature (1985) 4.01
Dimers, leucine zippers and DNA-binding domains. Trends Genet (1990) 3.98
Conditional site-specific recombination in mammalian cells using a ligand-dependent chimeric Cre recombinase. Proc Natl Acad Sci U S A (1995) 3.94
Distinct classes of transcriptional activating domains function by different mechanisms. Cell (1990) 3.75
A third human retinoic acid receptor, hRAR-gamma. Proc Natl Acad Sci U S A (1989) 3.74
Cloning of murine alpha and beta retinoic acid receptors and a novel receptor gamma predominantly expressed in skin. Nature (1989) 3.72
Cloning, expression, and transcriptional properties of the human enhancer factor TEF-1. Cell (1991) 3.71
Heterochromatin formation in mammalian cells: interaction between histones and HP1 proteins. Mol Cell (2001) 3.70
Induction of altered chromatin structures by simian virus 40 enhancer and promoter elements. Nature (1984) 3.68
The coactivator TIF2 contains three nuclear receptor-binding motifs and mediates transactivation through CBP binding-dependent and -independent pathways. EMBO J (1998) 3.64
Multiplicity generates diversity in the retinoic acid signalling pathways. Trends Biochem Sci (1992) 3.63
Role of the two activating domains of the oestrogen receptor in the cell-type and promoter-context dependent agonistic activity of the anti-oestrogen 4-hydroxytamoxifen. EMBO J (1990) 3.59
High mutation rate of a spleen necrosis virus-based retrovirus vector. Mol Cell Biol (1986) 3.57
Function of the retinoic acid receptors (RARs) during development (II). Multiple abnormalities at various stages of organogenesis in RAR double mutants. Development (1994) 3.53
Disruption of the Hox-1.6 homeobox gene results in defects in a region corresponding to its rostral domain of expression. Cell (1991) 3.53
Steroid hormone receptors compete for factors that mediate their enhancer function. Cell (1989) 3.50
Human TAFII30 is present in a distinct TFIID complex and is required for transcriptional activation by the estrogen receptor. Cell (1994) 3.46
The HeLa cell protein TEF-1 binds specifically and cooperatively to two SV40 enhancer motifs of unrelated sequence. Cell (1988) 3.41
Isolation by molecular cloning of a fragment in the split ovalbumin gene. Nature (1978) 3.40