PubRank

H M Temin

Author PubWeight™ 362.02‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 RNA-dependent DNA polymerase in virions of Rous sarcoma virus. Nature 1970 19.89
2 Lower in vivo mutation rate of human immunodeficiency virus type 1 than that predicted from the fidelity of purified reverse transcriptase. J Virol 1995 9.02
3 Genetic consequences of packaging two RNA genomes in one retroviral particle: pseudodiploidy and high rate of genetic recombination. Proc Natl Acad Sci U S A 1990 6.66
4 Standardized and simplified nomenclature for proteins common to all retroviruses. J Virol 1988 6.31
5 Retroviral recombination and reverse transcription. Science 1990 6.27
6 RNA-directed DNA synthesis and RNA tumor viruses. Adv Virus Res 1972 6.11
7 Sequence of retrovirus provirus resembles that of bacterial transposable elements. Nature 1980 5.95
8 Encapsidation sequences for spleen necrosis virus, an avian retrovirus, are between the 5' long terminal repeat and the start of the gag gene. Proc Natl Acad Sci U S A 1982 5.56
9 Construction of a helper cell line for avian reticuloendotheliosis virus cloning vectors. Mol Cell Biol 1983 4.96
10 Structure, variation and synthesis of retrovirus long terminal repeat. Cell 1981 4.90
11 The terminal nucleotides of retrovirus DNA are required for integration but not virus production. Nature 1984 4.89
12 The retrovirus pol gene encodes a product required for DNA integration: identification of a retrovirus int locus. Proc Natl Acad Sci U S A 1984 4.81
13 Broad spectrum of in vivo forward mutations, hypermutations, and mutational hotspots in a retroviral shuttle vector after a single replication cycle: substitutions, frameshifts, and hypermutations. Proc Natl Acad Sci U S A 1990 4.72
14 Studies on carcinogenesis by avian sarcoma viruses. VI. Differential multiplication of uninfected and of converted cells in response to insulin. J Cell Physiol 1967 4.55
15 Genes with promoters in retrovirus vectors can be independently suppressed by an epigenetic mechanism. Cell 1984 4.29
16 Mechanism of cell transformation by RNA tumor viruses. Annu Rev Microbiol 1971 4.24
17 Nucleic acid sequences of the oncogene v-rel in reticuloendotheliosis virus strain T and its cellular homolog, the proto-oncogene c-rel. J Virol 1984 4.17
18 Carcinogenesis by RNA sarcoma viruses. XII. A quantitative study of infection of rat cells in vitro by avian sarcoma viruses. Virology 1970 3.90
19 Formation of infectious progeny virus after insertion of herpes simplex thymidine kinase gene into DNA of an avian retrovirus. Cell 1981 3.80
20 Broad spectrum of in vivo forward mutations, hypermutations, and mutational hotspots in a retroviral shuttle vector after a single replication cycle: deletions and deletions with insertions. Proc Natl Acad Sci U S A 1990 3.76
21 Origin of retroviruses from cellular moveable genetic elements. Cell 1980 3.67
22 Lack of sequence homology among RNAs of avian leukosis-sarcoma viruses, reticuloendotheliosis viruses, and chicken endogenous RNA-directed DNA polymerase activity. J Virol 1973 3.62
23 High mutation rate of a spleen necrosis virus-based retrovirus vector. Mol Cell Biol 1986 3.57
24 Correlation between cell killing and massive second-round superinfection by members of some subgroups of avian leukosis virus. J Virol 1980 3.53
25 Circles with two tandem LTRs are precursors to integrated retrovirus DNA. Cell 1984 3.45
26 Stimulation by serum of multiplication of stationary chicken cells. J Cell Physiol 1971 3.41
27 Cell cycle-dependent activation of rous sarcoma virus-infected stationary chicken cells: avian leukosis virus group-specific antigens and ribonucleic acid. J Virol 1972 3.35
28 A DNA-depenent DNA polymerase and a DNA endonuclease in virions of Rous sarcoma virus. Nature 1970 3.31
29 Formation and structure of infectious DNA of spleen necrosis virus. J Virol 1977 3.29
30 Replication of reticuloendotheliosis viruses in cell culture: acute infection. J Virol 1974 3.17
31 High-efficiency ligation and recombination of DNA fragments by vertebrate cells. Science 1983 2.99
32 Comparison of Rous sarcoma virus-specific deoxyribonucleic acid polymerases in virions of Rous sarcoma virus and in Rous sarcoma virus-infected chicken cells. J Virol 1971 2.97
33 Function of the retrovirus long terminal repeat. Cell 1982 2.89
34 Determination of the rate of base-pair substitution and insertion mutations in retrovirus replication. J Virol 1988 2.88
35 New retrovirus helper cells with almost no nucleotide sequence homology to retrovirus vectors. J Virol 1989 2.86
36 Requirement for cell division for initiation of transcription of Rous sarcoma virus RNA. J Virol 1974 2.86
37 Infectious rous sarcoma virus and reticuloendotheliosis virus DNAs. J Virol 1974 2.77
38 Inhibition of viral DNA synthesis in stationary chicken embryo fibroblasts infected with avian retroviruses. J Virol 1977 2.71
39 Rate and mechanism of nonhomologous recombination during a single cycle of retroviral replication. Science 1993 2.64
40 Reticuloendotheliosis virus nucleic acid sequences in cellular DNA. J Virol 1974 2.55
41 Lack of competition results in efficient packaging of heterologous murine retroviral RNAs and reticuloendotheliosis virus encapsidation-minus RNAs by the reticuloendotheliosis virus helper cell line. J Virol 1987 2.51
42 Characterization of reticuloendotheliosis virus strain T DNA and isolation of a novel variant of reticuloendotheliosis virus strain T by molecular cloning. J Virol 1981 2.49
43 Lack of serological relationship among DNA polymerases of avian leukosis-sarcoma viruses, reticuloendotheliosis viruses, and chicken cells. J Virol 1973 2.46
44 Loss of intervening sequences in genomic mouse alpha-globin DNA inserted in an infectious retrovirus vector. Nature 1982 2.38
45 The partial purification from calf serum of a fraction with multiplication-stimulating activity for chicken fibroblasts in cell culture and with non-suppressible insulin-like activity. J Cell Physiol 1972 2.37
46 Infectious and noninfectious recombinant clones of the provirus of SNV differ in cellular DNA and are apparently the same in viral DNA. Cell 1980 2.35
47 Characterization of large deletions occurring during a single round of retrovirus vector replication: novel deletion mechanism involving errors in strand transfer. J Virol 1991 2.34
48 Cell killing by spleen necrosis virus is correlated with a transient accumulation of spleen necrosis virus DNA. J Virol 1979 2.33
49 The DNA provirus hypothesis. Science 1976 2.31
50 Establishment of infection by spleen necrosis virus: inhibition in stationary cells and the role of secondary infection. J Virol 1982 2.26
51 Studies on carcinogenesis by avian sarcoma viruses. 8. Glycolysis and cell multiplication. Int J Cancer 1968 2.25
52 Spontaneous changes in nucleotide sequence in proviruses of spleen necrosis virus, an avian retrovirus. Proc Natl Acad Sci U S A 1982 2.16
53 A promoterless retroviral vector indicates that there are sequences in U3 required for 3' RNA processing. Proc Natl Acad Sci U S A 1987 2.13
54 Cell killing by avian leukosis viruses. J Virol 1981 2.10
55 Quantitative analysis of gene suppression in integrated retrovirus vectors. Mol Cell Biol 1986 2.08
56 v-rel oncoproteins in the nucleus and in the cytoplasm transform chicken spleen cells. J Virol 1988 2.08
57 5-Azacytidine and RNA secondary structure increase the retrovirus mutation rate. J Virol 1992 2.03
58 Light inactivation of focus formation by chicken embryo fibroblasts infected with avian sarcoma virus in the presence of 5-bromodeoxyuridine. Nature 1970 2.02
59 Lack of infectivity of the endogenous avian leukosis virus-related genes in the DNA of uninfected chicken cells. J Virol 1976 1.99
60 Different localization of the product of the v-rel oncogene in chicken fibroblasts and spleen cells correlates with transformation by REV-T. Cell 1986 1.96
61 A partially purified polypeptide fraction from rat liver cell conditioned medium with multiplication-stimulating activity for embryo fibroblasts. J Cell Physiol 1973 1.93
62 The protovirus hypothesis: speculations on the significance of RNA-directed DNA synthesis for normal development and for carcinogenesis. J Natl Cancer Inst 1971 1.93
63 Hybridization of Rous sarcoma virus deoxyribonucleic acid polymerase product and ribonucleic acids from chicken and rat cells infected with Rous sarcoma virus. J Virol 1972 1.91
64 Multiplication-stimulating activity for chicken embryo fibroblasts from rat liver cell conditioned medium: a family of small polypeptides. J Cell Physiol 1973 1.87
65 Transactivation of gene expression by nuclear and cytoplasmic rel proteins. Mol Cell Biol 1989 1.87
66 Sites of integration of reticuloendotheliosis virus DNA in chicken DNA. Proc Natl Acad Sci U S A 1978 1.86
67 Insertion of several different DNAs in reticuloendotheliosis virus strain T suppresses transformation by reducing the amount of subgenomic mRNA. J Virol 1986 1.83
68 The mechanism of carcinogenesis by avian sarcoma viruses. 1. Cell multiplication and differentiation. J Natl Cancer Inst 1965 1.82
69 The cellular and molecular biology of RNA tumor viruses, especially avian leukosis-sarcoma viruses, and their relatives. Adv Cancer Res 1974 1.81
70 Instability of large direct repeats in retrovirus vectors. J Virol 1987 1.78
71 Lower mutation rate of bovine leukemia virus relative to that of spleen necrosis virus. J Virol 1994 1.76
72 Enzymes and nucleotides in virions of Rous sarcoma virus. J Virol 1971 1.74
73 Reverse transcriptases. Retrons in bacteria. Nature 1989 1.74
74 High-frequency deletion in recovered retrovirus vectors containing exogenous DNA with promoters. J Virol 1984 1.73
75 No apparent nucleotide sequence specificity in cellular DNA juxtaposed to retrovirus proviruses. Proc Natl Acad Sci U S A 1980 1.72
76 DNA of noninfectious and infectious integrated spleen necrosis virus (SNV) is colinear with unintegrated SNV DNA and not grossly abnormal. Cell 1979 1.71
77 DNA ligase and exonuclease activities in virions of rous sarcoma virus. Nat New Biol 1971 1.71
78 Retrovirus recombination depends on the length of sequence identity and is not error prone. J Virol 1994 1.70
79 Spontaneous variation and synthesis in the U3 region of the long terminal repeat of an avian retrovirus. J Virol 1982 1.69
80 Substitution of 5' helper virus sequences into non-rel portion of reticuloendotheliosis virus strain T suppresses transformation of chicken spleen cells. Cell 1982 1.69
81 Replication of reticuloendotheliosis viruses in cell culture: chronic infection. J Gen Virol 1975 1.68
82 Specific serological relationships among partially purified DNA polymerases of avian leukosis-sarcoma viruses, reticuloendotheliosis viruses, and avian cells. J Virol 1974 1.61
83 One retroviral RNA is sufficient for synthesis of viral DNA. J Virol 1994 1.60
84 Infectious DNA of spleen necrosis virus is integrated at a single site in the DNA of chronically infected chicken fibroblasts. Proc Natl Acad Sci U S A 1977 1.58
85 Expression of complete chicken thymidine kinase gene inserted in a retrovirus vector. Mol Cell Biol 1984 1.58
86 A double hairpin structure is necessary for the efficient encapsidation of spleen necrosis virus retroviral RNA. EMBO J 1994 1.58
87 Sites of integration of infectious DNA of avian reticuloendotheliosis viruses in different avian cellular DNAs. Cell 1978 1.57
88 The RNA tumor viruses--background and foreground. Proc Natl Acad Sci U S A 1972 1.56
89 Ribonuclease-sensitive deoxyribonucleic acid polymerase activity in uninfected rat cells and rat cells infected with Rous sarcoma virus. J Virol 1971 1.54
90 On the origin of RNA tumor viruses. Annu Rev Genet 1974 1.53
91 Recombination of transfected DNAs in vertebrate cells in culture. Proc Natl Acad Sci U S A 1984 1.50
92 Retroviral vector system for the study of cDNA gene formation. Mol Cell Biol 1988 1.50
93 Endogenous RNA-directed DNA polymerase activity in uninfected chicken embryos. Proc Natl Acad Sci U S A 1972 1.49
94 Control by factors in serum of multiplication of uninfected cells and cells infected and converted by avian sarcoma viruses. Wistar Inst Symp Monogr 1967 1.46
95 Effect of gamma radiation on retroviral recombination. J Virol 1992 1.43
96 Expression from an internal AUG codon of herpes simplex thymidine kinase gene inserted in a retrovirus vector. Mol Cell Biol 1984 1.42
97 The v-rel oncogene encodes a cell-specific transcriptional activator of certain promoters. Oncogene 1988 1.41
98 Studies on carcinogenesis by avian sarcoma viruses. 3. The differential effect of serum and polyanions on multiplication of uninfected and converted cells. J Natl Cancer Inst 1966 1.41
99 Structure and expression of c-rel, the cellular homolog to the oncogene of reticuloendotheliosis virus strain T. J Virol 1983 1.40
100 The efficiency of RNA 3'-end formation is determined by the distance between the cap site and the poly(A) site in spleen necrosis virus. Genes Dev 1990 1.37
101 Purified multiplication-stimulating activity from rat liver cell conditioned medium: comparison of biological activities with calf serum, insulin, and somatomedin. J Cell Physiol 1974 1.37
102 3' junctions of oncogene-virus sequences and the mechanisms for formation of highly oncogenic retroviruses. J Virol 1993 1.36
103 Structure and autoregulation of the c-rel promoter. Oncogene 1990 1.35
104 Unusually high frequency of reconstitution of long terminal repeats in U3-minus retrovirus vectors by DNA recombination or gene conversion. J Virol 1992 1.32
105 Activation of oncogenicity of the c-rel proto-oncogene. Mol Cell Biol 1986 1.31
106 High spontaneous mutation rate of an avian sarcoma virus. J Virol 1975 1.31
107 Carcinogenesis by avian sarcoma viruses. X. The decreased requirement for insulin-replaceable activity in serum for cell multiplication. Int J Cancer 1968 1.29
108 Endogenous RNA-directed DNA polymerase activity in virions of RNA tumor viruses and in a fraction from normal chicken cells. Methods Enzymol 1974 1.25
109 The location of v-src in a retrovirus vector determines whether the virus is toxic or transforming. Mol Cell Biol 1984 1.24
110 Studies of carcinogenesis by avian sarcoma viruses. II. Virus-induced increase in hyaluronic acid synthetase in chicken fibroblasts. J Biol Chem 1966 1.24
111 Mapping of alterations in noninfectious proviruses of spleen necrosis virus. J Virol 1981 1.24
112 Correlation of transient accumulation of linear unintegrated viral DNA and transient cell killing by avian leukosis and reticuloendotheliosis viruses. Cold Spring Harb Symp Quant Biol 1980 1.23
113 Structure and dimorphism of c-rel (turkey), the cellular homolog to the oncogene of reticuloendotheliosis virus strain T. J Virol 1984 1.23
114 Bovine leukaemia virus packaging cell line for retrovirus-mediated gene transfer. J Gen Virol 1989 1.23
115 Alteration of location of dimer linkage sequence in retroviral RNA: little effect on replication or homologous recombination. J Virol 1993 1.21
116 Malignant transformation of cells by viruses. Perspect Biol Med 1970 1.18
117 Specific antigenic relationships between the RNA-dependent DNA polymerases of avian reticuloendotheliosis viruses and mammalian type C retroviruses. J Virol 1980 1.17
118 Comparison of promoter suppression in avian and murine retrovirus vectors. Nucleic Acids Res 1986 1.17
119 Incorporation of noncomplementary nucleotides at high frequencies by ribodeoxyvirus DNA polymerases and Escherichia coli DNA polymerase I. Biochemistry 1976 1.17
120 High rate of mismatch extension during reverse transcription in a single round of retrovirus replication. Proc Natl Acad Sci U S A 1994 1.16
121 Radioimmunological comparison of the DNA polymerases of avian retroviruses. J Virol 1980 1.16
122 Nondefective spleen necrosis virus-derived vectors define the upper size limit for packaging reticuloendotheliosis viruses. Proc Natl Acad Sci U S A 1986 1.16
123 On the origin of the genes for neoplasia: G.H.A. Clowes memorial lecture. Cancer Res 1974 1.16
124 Transforming viruses spontaneously arise from nontransforming reticuloendotheliosis virus strain T-derived viruses as a result of increased accumulation of spliced viral RNA. J Virol 1988 1.15
125 Pseudotyped retroviral vectors reveal restrictions to reticuloendotheliosis virus replication in rat cells. J Virol 1986 1.12
126 High rates of frameshift mutations within homo-oligomeric runs during a single cycle of retroviral replication. J Virol 1994 1.12
127 Ribonucleotides in unintegrated linear spleen necrosis virus DNA. J Virol 1980 1.12
128 Avian leukosis viruses of different subgroups and types isolated after passage of Rous sarcoma virus-Rous-associated virus-0 in cells from different ring-necked pheasant embryos. J Virol 1976 1.12
129 Lack of correlation between conversion of RNA tumour viruses and increased agglutinability of cells by concanavalin A and wheat germ agglutinin. Nature 1971 1.11
130 The bovine leukemia virus encapsidation signal is discontinuous and extends into the 5' end of the gag gene. J Virol 1995 1.11
131 Recent advances in retrovirus vector technology. Curr Opin Genet Dev 1993 1.11
132 Purification and properties of spleen necrosis virus DNA polymerase. J Virol 1975 1.10
133 AIDS. Where has HIV been hiding? Nature 1993 1.09
134 HIV causes AIDS. Science 1988 1.09
135 Control of cell multiplication in uninfected chicken cells and chicken cells converted by avian sarcoma viruses. J Cell Physiol 1969 1.08
136 Nucleotide sequences derived from pheasant DNA in the genome of recombinant avian leukosis viruses with subgroup F specificity. J Virol 1977 1.07
137 Early DNA-RNA complex from the endogenous RNA-directed DNA polymerase activity of uninfected chicken embryos. Nat New Biol 1973 1.07
138 Carcinogenesis by avian sarcoma viruses. Cancer Res 1968 1.04
139 Control of multiplication of uninfected rat cells and rat cells converted by murine sarcoma virus. J Cell Physiol 1970 1.01
140 cDNA genes formed after infection with retroviral vector particles lack the hallmarks of natural processed pseudogenes. Mol Cell Biol 1990 0.97
141 Genetically simpler bovine leukemia virus derivatives can replicate independently of Tax and Rex. J Virol 1995 0.96
142 Presence of a retroviral encapsidation sequence in nonretroviral RNA increases the efficiency of formation of cDNA genes. J Virol 1990 0.95
143 Transcription from a spleen necrosis virus 5' long terminal repeat is suppressed in mouse cells. J Virol 1987 0.95
144 In vivo study of genetically simplified bovine leukemia virus derivatives that lack tax and rex. J Virol 1997 0.92
145 Suppression of multiplication of avian sarcoma virus by rapid spread of transformation-defective virus of the same subgroup. J Virol 1979 0.91
146 RNA-directed DNA polymerase from particles released by normal goose cells. J Virol 1979 0.90
147 Do we understand the genetic mechanisms of oncogenesis? Keynote address for Honey Harbor meeting on cellular and molecular biology of neoplasia, October 2-6, 1983. J Cell Physiol Suppl 1984 0.88
148 Evolution of retroviruses from cellular movable genetic elements. Cold Spring Harb Symp Quant Biol 1981 0.88
149 Mutational analysis of v-rel, the oncogene of reticuloendotheliosis virus strain T. Oncogene 1990 0.87
150 Retroviruses and evolution. Cell Biophys 1986 0.86
151 Viruses, protoviruses, development, and evolution. J Cell Biochem 1982 0.85
152 The organization of c-rel in chicken and turkey DNAS. Prog Clin Biol Res 1983 0.85
153 The U3 region is not necessary for 3' end formation of spleen necrosis virus RNA. J Virol 1990 0.84
154 Carcinogenesis by RNA sarcoma viruses. XIV. Infection of stationary cultures with murine sarcoma virus (Harvey). Int J Cancer 1970 0.83
155 Multiple sequence elements are involved in RNA 3' end formation in spleen necrosis virus. Gene Expr 1992 0.82
156 Copackaging of different-sized retroviral genomic RNAs: little effect on retroviral replication or recombination. J Virol 1994 0.82
157 Determination of retroviral mutation rates using spleen necrosis virus-based vectors and helper cells. Biotechnology 1991 0.81
158 RNA polymerase activity in purified virions of avian reticuloendotheliosis viruses. J Virol 1976 0.81
159 Cellular DNA surrounding integration sites of an avian retrovirus. J Gen Virol 1983 0.80
160 Spontaneous mutations affecting the host range of the B77 strain of avian sarcoma virus involve type-specific changes in the virion envelope antigen. J Virol 1977 0.80
161 Infectious DNA from cells infected with Rous sarcoma virus, reticuloendotheliosis virus or Rous-associated virus-O. Cold Spring Harb Symp Quant Biol 1975 0.79
162 Possible implications for medicine of RNA-directed DNA synthesis. Triangle 1972 0.78
163 The retroviral vector. Replication cycle and safety considerations for retrovirus-mediated gene therapy. Ann N Y Acad Sci 1994 0.78
164 Pheasant virus DNA polymerase is related to avian leukosis virus DNA polymerase at the active site. J Virol 1979 0.78
165 Molecular mechanisms of transformation by the v-rel oncogene. Crit Rev Oncog 1991 0.78
166 Viral oncogenes. Cold Spring Harb Symp Quant Biol 1980 0.77
167 Genetic and possible biochemical mechanisms in viral carcinogenesis. Cancer Res 1966 0.77
168 We still don't understand cancer. Nature 1983 0.76
169 The recombination rate is not increased when retroviral RNA is missing an encapsidation sequence. J Virol 1996 0.76
170 Insertion of genes into retrovirus genomes and of retrovirus DNA into cell genomes. Prog Med Virol 1985 0.76
171 Introduction to virus-caused cancers. Cancer 1974 0.75
172 RNA viruses, cancer and development. Results Probl Cell Differ 1980 0.75
173 Ribodeoxyviruses and cancer. JAMA 1974 0.75
174 Genetic mechanisms of oncogenesis. Carcinog Compr Surv 1985 0.75
175 Retroviruses and cancer. Mol Carcinog 1990 0.75
176 Moscow genetics congress. Science 1978 0.75
177 RNA-directed DNA polymerase systems: not necessarily transforming Rous viruses. J Natl Cancer Inst 1972 0.75
178 Relationships among RNA-directed DNA polymerase activities of avian viruses and chicken cells. Cold Spring Harb Symp Quant Biol 1974 0.75
179 The relevance of RNA-directed DNA polymerase activity to human neoplasia. Hamatol Bluttransfus 1974 0.75
180 Cancer congress in Argentina. Science 1977 0.75
181 Altered properties of Fujinami-virus-infected duck cells and murine sarcoma virus-infected rat cells. Int J Cancer 1968 0.75
182 How do viruses cause cancer? New Horizons for Radiologists Lecture. Radiology 1969 0.75
183 RNA viruses and cancer: Lucy Wortham James Lecture (Basic Science). Cancer 1977 0.75
184 On the origin of RNA tumor viruses. Harvey Lect 1975 0.75
185 RNA-dependent DNA polymerase in virions of Rous sarcoma virus. 1970. Biotechnology 1992 0.75
186 Evolution of RNA tumor viruses: analogy for nonviral carcinogenesis. Prog Nucleic Acid Res Mol Biol 1983 0.75
187 RNA-directed DNA synthesis. Sci Am 1972 0.75
188 [Retroviruses and the genetics of cancer]. Rev Prat 1987 0.75
189 Endogenous RNA-directed DNA polymerase activity in normal cells. Johns Hopkins Med J Suppl 1973 0.75
190 Proceedings: Molecular mechanisms for cancer induction by viruses. Proc Natl Cancer Conf 1972 0.75