Published in Jikken Dobutsu on January 01, 1991
The bald and the beautiful: hairlessness in domestic dog breeds. Philos Trans R Soc Lond B Biol Sci (2017) 0.76
The transcriptional landscape of the mammalian genome. Science (2005) 37.63
Long-term lymphohematopoietic reconstitution by a single CD34-low/negative hematopoietic stem cell. Science (1996) 12.54
Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity. Proc Natl Acad Sci U S A (1993) 11.95
A novel repeated element with Z-DNA-forming potential is widely found in evolutionarily diverse eukaryotic genomes. Proc Natl Acad Sci U S A (1982) 8.15
Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues. Proc Natl Acad Sci U S A (1987) 7.38
Molecular structure and evolutionary origin of human cardiac muscle actin gene. Proc Natl Acad Sci U S A (1982) 4.97
Molecular structure of the human cytoplasmic beta-actin gene: interspecies homology of sequences in the introns. Proc Natl Acad Sci U S A (1985) 4.80
Enhanced gene expression by the poly(dT-dG).poly(dC-dA) sequence. Mol Cell Biol (1984) 4.44
Potential Z-DNA forming sequences are highly dispersed in the human genome. Nature (1982) 4.41
Effects of environmental tobacco smoke on urinary cotinine excretion in nonsmokers. Evidence for passive smoking. N Engl J Med (1984) 3.98
A novel octamer binding transcription factor is differentially expressed in mouse embryonic cells. Cell (1990) 3.97
Left-right asymmetric expression of the TGF beta-family member lefty in mouse embryos. Nature (1996) 3.79
Characterization of genomic poly(dT-dG).poly(dC-dA) sequences: structure, organization, and conformation. Mol Cell Biol (1984) 3.42
Clinical features of isolated noncompaction of the ventricular myocardium: long-term clinical course, hemodynamic properties, and genetic background. J Am Coll Cardiol (1999) 3.38
Results of an international, randomized trial comparing glucose metabolism disorders and outcome with cyclosporine versus tacrolimus. Am J Transplant (2007) 3.26
Functional role for the 170- to 180-kDa glycoprotein specific to drug-resistant tumor cells as revealed by monoclonal antibodies. Proc Natl Acad Sci U S A (1986) 2.99
Intravenous infusion of immortalized human mesenchymal stem cells protects against injury in a cerebral ischemia model in adult rat. Exp Neurol (2005) 2.97
Antitumor effect of genetically engineered mesenchymal stem cells in a rat glioma model. Gene Ther (2004) 2.97
lefty-1 is required for left-right determination as a regulator of lefty-2 and nodal. Cell (1998) 2.63
Abnormal nodal flow precedes situs inversus in iv and inv mice. Mol Cell (1999) 2.55
cDNA cloning and tissue-specific expression of a novel basic helix-loop-helix/PAS factor (Arnt2) with close sequence similarity to the aryl hydrocarbon receptor nuclear translocator (Arnt). Mol Cell Biol (1996) 2.42
Tissue distribution of P-glycoprotein encoded by a multidrug-resistant gene as revealed by a monoclonal antibody, MRK 16. Cancer Res (1988) 2.35
Transcriptional and posttranscriptional regulation of tumor necrosis factor gene expression in human monocytes. J Clin Invest (1988) 2.29
v-maf, a viral oncogene that encodes a "leucine zipper" motif. Proc Natl Acad Sci U S A (1989) 2.24
Structure of a human smooth muscle actin gene (aortic type) with a unique intron site. Mol Cell Biol (1984) 2.11
The POU domain transcription factor Brn-2 is required for the determination of specific neuronal lineages in the hypothalamus of the mouse. Genes Dev (1995) 2.11
Angiotensin II type 1a receptor-deficient mice with hypotension and hyperreninemia. J Biol Chem (1995) 2.11
Incidence of portal vein thrombosis in liver cirrhosis. An angiographic study in 708 patients. Gastroenterology (1985) 2.11
The retinoic acid-inactivating enzyme CYP26 is essential for establishing an uneven distribution of retinoic acid along the anterio-posterior axis within the mouse embryo. Genes Dev (2001) 2.04
Prune-belly syndrome diagnosed at 14 weeks' gestation with severe urethral obstruction but normal kidneys. Pediatr Nephrol (1999) 2.00
Metabolic inactivation of retinoic acid by a novel P450 differentially expressed in developing mouse embryos. EMBO J (1997) 1.96
Pitx2, a bicoid-type homeobox gene, is involved in a lefty-signaling pathway in determination of left-right asymmetry. Cell (1998) 1.93
Cloning of inv, a gene that controls left/right asymmetry and kidney development. Nature (1998) 1.90
Immunohistochemical localization in normal tissues of different epitopes in the multidrug transport protein P170: evidence for localization in brain capillaries and crossreactivity of one antibody with a muscle protein. J Histochem Cytochem (1989) 1.89
Manipulation of the small intestine as a cause of the increased inflammatory response after open compared with laparoscopic surgery. Br J Surg (2006) 1.88
Mouse Lefty2 and zebrafish antivin are feedback inhibitors of nodal signaling during vertebrate gastrulation. Mol Cell (1999) 1.87
Variations in expression of mutant beta actin accompanying incremental increases in human fibroblast tumorigenicity. Cell (1982) 1.86
Auxin is a positive regulator for ethylene-mediated response in the growth of Arabidopsis roots. Plant Cell Physiol (2001) 1.80
On the adsorption of proteins on solid surfaces, a common but very complicated phenomenon. J Biosci Bioeng (2001) 1.80
Suppression of phytohemagglutinin skin response in thymectomized chickens. Poult Sci (1978) 1.79
A novel fibrinolytic enzyme (nattokinase) in the vegetable cheese Natto; a typical and popular soybean food in the Japanese diet. Experientia (1987) 1.78
Left-right asymmetric expression of lefty2 and nodal is induced by a signaling pathway that includes the transcription factor FAST2. Mol Cell (2000) 1.78
Two-step regulation of left-right asymmetric expression of Pitx2: initiation by nodal signaling and maintenance by Nkx2. Mol Cell (2001) 1.77
Recombinant human tumor necrosis factor administered as a 24-hour intravenous infusion. A phase I and pharmacologic study. J Natl Cancer Inst (1988) 1.73
The oct3 gene, a gene for an embryonic transcription factor, is controlled by a retinoic acid repressible enhancer. EMBO J (1991) 1.70
I.V. infusion of brain-derived neurotrophic factor gene-modified human mesenchymal stem cells protects against injury in a cerebral ischemia model in adult rat. Neuroscience (2005) 1.70
Two new members of the murine Sim gene family are transcriptional repressors and show different expression patterns during mouse embryogenesis. Mol Cell Biol (1996) 1.69
Characterization of a cell type-specific enhancer found in the human papilloma virus type 18 genome. EMBO J (1987) 1.67
CT findings during phase of accelerated deterioration in patients with idiopathic pulmonary fibrosis. AJR Am J Roentgenol (1997) 1.58
The transcription factor FoxH1 (FAST) mediates Nodal signaling during anterior-posterior patterning and node formation in the mouse. Genes Dev (2001) 1.54
Tumor necrosis factor expression in human epithelial tumor cell lines. J Clin Invest (1988) 1.53
Evaluation of tri-combinant vaccine for feline herpesvirus, calicivirus and panleukopenia virus infections in Japanese native cats. Jikken Dobutsu (1985) 1.51
Targeting endogenous platelet-derived growth factor B-chain by adenovirus-mediated gene transfer potently inhibits in vivo smooth muscle proliferation after arterial injury. Gene Ther (1999) 1.51
Two closely-related left-right asymmetrically expressed genes, lefty-1 and lefty-2: their distinct expression domains, chromosomal linkage and direct neuralizing activity in Xenopus embryos. Genes Cells (1997) 1.50
Quantitative in vivo measurement of thyroidal iodine content by static x-ray fluorescent technique: some preliminary clinical observations. Invest Radiol (1979) 1.49
Adoptive transfer of T-helper cell type 1 clones attenuates an asthmatic phenotype in mice. Eur Respir J (2005) 1.49
Multimolecular forms of pyruvate kinase from rat and other mammalian tissues. I. Electrophoretic studies. J Biochem (1972) 1.48
Combined endoscopic clipping and ethanol injection for treatment of Dieulafoy's lesions in the duodenum. Gastrointest Endosc (1997) 1.48
Enhancement of the fibrinolytic activity in plasma by oral administration of nattokinase. Acta Haematol (1990) 1.46
Neuroprotection by PlGF gene-modified human mesenchymal stem cells after cerebral ischaemia. Brain (2006) 1.46
Olivary enlargement: chronological and morphometric analyses. Acta Neuropathol (1981) 1.44
Role of cytokines in inflammatory process in Parkinson's disease. J Neural Transm Suppl (2006) 1.43
Establishment and characterization of a novel malignant astrocytoma cell line derived from a tumor removed in a patient with neurofibromatosis type 1. J Neurosurg (2001) 1.39
Growth rates of abdominal aortic aneurysms in Japanese patients observed in one institute. Int Angiol (2012) 1.39
Caspase-9 transduction overrides the resistance mechanism against p53-mediated apoptosis in U-87MG glioma cells. Neurosurgery (2001) 1.39
Circulating KL-6 predicts the outcome of rapidly progressive idiopathic pulmonary fibrosis. Am J Respir Crit Care Med (1998) 1.39
Electroconvulsive therapy using rocuronium and sugammadex in patient with neuroleptic malignant syndrome. Anaesth Intensive Care (2011) 1.38
KL-6, a mucin-like glycoprotein, in bronchoalveolar lavage fluid from patients with interstitial lung disease. Am Rev Respir Dis (1993) 1.38
Recombinant human tumor necrosis factor administered as a five-day continuous infusion in cancer patients: phase I toxicity and effects on lipid metabolism. J Clin Oncol (1988) 1.37
Proteasome inhibitors induce cytochrome c-caspase-3-like protease-mediated apoptosis in cultured cortical neurons. J Neurosci (2000) 1.37
Protein phylogeny gives a robust estimation for early divergences of eukaryotes: phylogenetic place of a mitochondria-lacking protozoan, Giardia lamblia. Mol Biol Evol (1994) 1.36
Mutated beta-actin gene: coexpression with an unmutated allele in a chemically transformed human fibroblast cell line. Proc Natl Acad Sci U S A (1981) 1.36
Circulating interleukin-6 levels in patients with bronchial asthma. Am J Respir Crit Care Med (1995) 1.34
Proteome analysis of rat hepatic stellate cells. Hepatology (2000) 1.34
Induction of tumor necrosis factor expression and resistance in a human breast tumor cell line. Proc Natl Acad Sci U S A (1987) 1.34
Obesity, weight gain and risk of colon adenomas in Japanese men. Jpn J Cancer Res (1999) 1.31
An avian transforming retrovirus isolated from a nephroblastoma that carries the fos gene as the oncogene. J Virol (1987) 1.31
Adoptive immunotherapy with murine tumor-specific T lymphocytes engineered to secrete interleukin 2. Cancer Res (1994) 1.30
High level calcineurin activity predisposes neuronal cells to apoptosis. J Biol Chem (1999) 1.28
Characteristics of resistance to adriamycin in human myelogenous leukemia K562 resistant to adriamycin and in isolated clones. Jpn J Cancer Res (1986) 1.26
Gut cryptopatches: direct evidence of extrathymic anatomical sites for intestinal T lymphopoiesis. Immunity (2000) 1.25
Base composition of deoxyribonucleic acid of the temperature-sensitive kanamycin-resistant R factor, Rts1. J Bacteriol (1970) 1.24
Immunocytochemical observation of ghrelin-containing neurons in the rat arcuate nucleus. Neurosci Lett (2002) 1.23
Early results of a prospective study of limited resection for bronchioloalveolar adenocarcinoma of the lung. Ann Thorac Surg (2001) 1.22
A monoclonal antibody-Pseudomonas toxin conjugate that specifically kills multidrug-resistant cells. Proc Natl Acad Sci U S A (1987) 1.21
Comparison of UDP-glucose:flavonoid 3-O-glucosyltransferase (UFGT) gene sequences between white grapes (Vitis vinifera) and their sports with red skin. Plant Sci (2001) 1.21
Role of prostaglandins in interleukin-1-induced bone resorption in mice in vitro. J Bone Miner Res (1991) 1.21
Interaction between polyamines and nucleic acids or phospholipids. Arch Biochem Biophys (1982) 1.20
Determination of left/right asymmetric expression of nodal by a left side-specific enhancer with sequence similarity to a lefty-2 enhancer. Genes Dev (1999) 1.20
Conduction of nonconjugative plasmids by F' lac is not necessarily associated with transposition of the gamma delta sequence. J Bacteriol (1984) 1.20
Structural organization and differential expression of rice alpha-amylase genes. Nucleic Acids Res (1990) 1.19
Multivariate analysis for clinical prognostic factors in 163 patients with soft tissue sarcoma. Cancer (1988) 1.19
Methylenetetrahydrofolate reductase polymorphism and pre-eclampsia. J Med Genet (1997) 1.19
A case of delayed brain abscess due to a retained intracranial wooden foreign body: a case report and review of the last 20 years. Acta Neurochir (Wien) (2004) 1.18
Formation of hilar collaterals or cavernous transformation after portal vein obstruction by hepatocellular carcinoma. Observations in ten patients. Gastroenterology (1984) 1.18
Dielectric properties of yeast cells. J Membr Biol (1976) 1.18
Negative association between Helicobacter pylori infection and reflux esophagitis in older patients: case-control study in Japan. Helicobacter (2000) 1.17
GFR alpha3, a component of the artemin receptor, is required for migration and survival of the superior cervical ganglion. Neuron (1999) 1.17
7-Methylxanthine methyltransferase of coffee plants. Gene isolation and enzymatic properties. J Biol Chem (2000) 1.17
Immunosuppressive properties of human amniotic membrane for mixed lymphocyte reaction. Clin Exp Immunol (2002) 1.17