Clinical features of isolated noncompaction of the ventricular myocardium: long-term clinical course, hemodynamic properties, and genetic background.

PubWeight™: 3.38‹?› | Rank: Top 1%

🔗 View Article (PMID 10400016)

Published in J Am Coll Cardiol on July 01, 1999

Authors

F Ichida1, Y Hamamichi, T Miyawaki, Y Ono, T Kamiya, T Akagi, H Hamada, O Hirose, T Isobe, K Yamada, S Kurotobi, H Mito, T Miyake, Y Murakami, T Nishi, M Shinohara, M Seguchi, S Tashiro, H Tomimatsu

Author Affiliations

1: Department of Pediatrics, Toyama Medical and Pharmaceutical University, Japan. fukiko@ms.toyama-mpu.ac.jp

Articles citing this

Echocardiographic and pathoanatomical characteristics of isolated left ventricular non-compaction: a step towards classification as a distinct cardiomyopathy. Heart (2001) 7.87

Cardiogenetics, neurogenetics, and pathogenetics of left ventricular hypertrabeculation/noncompaction. Pediatr Cardiol (2009) 2.54

Isolated ventricular non-compaction of the myocardium in adults. Heart (2006) 2.29

Extent of myocardial non-compaction: comparison between MRI and echocardiographic evaluation. Pediatr Radiol (2005) 1.85

The genetics of dilated cardiomyopathy. Curr Opin Cardiol (2010) 1.76

Wide spectrum of presentation and variable outcomes of isolated left ventricular non-compaction. Heart (2006) 1.53

Isolated noncompaction of the ventricular myocardium: ultrafast computed tomography and magnetic resonance imaging. Int J Cardiovasc Imaging (2001) 1.20

Isolated noncompaction of the left ventricular myocardium -- a review of the literature two decades after the initial case description. Clin Res Cardiol (2007) 1.18

Left ventricular noncompaction cardiomyopathy. Cardiovasc Diagn Ther (2013) 1.17

Noncompaction of the ventricular myocardium is associated with a de novo mutation in the beta-myosin heavy chain gene. PLoS One (2007) 1.15

Varied distributions of late gadolinium enhancement found among patients meeting cardiovascular magnetic resonance criteria for isolated left ventricular non-compaction. J Cardiovasc Magn Reson (2013) 1.12

Left ventricular non-compaction: clinical features and cardiovascular magnetic resonance imaging. BMC Cardiovasc Disord (2009) 1.07

Left ventricular non-compaction and its cardiac and neurologic implications. Heart Fail Rev (2010) 1.05

Hand factors as regulators of cardiac morphogenesis and implications for congenital heart defects. Birth Defects Res A Clin Mol Teratol (2011) 1.03

Unexpected finding in an adult with ventricular fibrillation and an accessory pathway: non-compaction cardiomyopathy. Neth Heart J (2014) 1.02

Inherited cardiomyopathies. Circ J (2014) 1.00

Noncompaction of the ventricular myocardium combined with polycystic kidney disease. Heart Vessels (2006) 1.00

A combination of right ventricular hypertrabeculation/noncompaction and arrhythmogenic right ventricular cardiomyopathy: a syndrome? Cardiovasc Ultrasound (2008) 0.99

Isolated left ventricular noncompaction: clinical profile and prognosis in 106 adult patients. Heart Vessels (2013) 0.99

Left ventricular noncompaction cardiomyopathy: cardiac, neuromuscular, and genetic factors. Nat Rev Cardiol (2017) 0.98

Tafazzin knockdown in mice leads to a developmental cardiomyopathy with early diastolic dysfunction preceding myocardial noncompaction. J Am Heart Assoc (2012) 0.98

Embryonic cardiac chamber maturation: Trabeculation, conduction, and cardiomyocyte proliferation. Am J Med Genet C Semin Med Genet (2013) 0.96

Left ventricular noncompaction diagnosed following Graves' disease. Avicenna J Med (2016) 0.93

Is left ventricular noncompaction in children truly an isolated lesion? Pediatr Cardiol (2009) 0.92

Pitfalls in the diagnosis of left ventricular hypertrabeculation/non-compaction. Postgrad Med J (2006) 0.91

Left-ventricular noncompaction in an infant with trisomy 21. Pediatr Cardiol (2012) 0.89

Comparison of cardiovascular magnetic resonance characteristics and clinical consequences in children and adolescents with isolated left ventricular non-compaction with and without late gadolinium enhancement. J Cardiovasc Magn Reson (2015) 0.89

Sildenafil for noncompaction cardiomyopathy treatment in a child: case report. Arq Bras Cardiol (2014) 0.88

A Rare Case of Renal Infarct due to Noncompaction Cardiomyopathy: A Case Report and Literature Review. Case Rep Cardiol (2016) 0.87

Transient postnatal heart failure caused by noncompaction of the right ventricular myocardium. Pediatr Cardiol (2005) 0.86

Cardiovascular magnetic resonance findings in a pediatric population with isolated left ventricular non-compaction. J Cardiovasc Magn Reson (2012) 0.86

Evolving molecular diagnostics for familial cardiomyopathies: at the heart of it all. Expert Rev Mol Diagn (2010) 0.85

Left ventricular non-compaction cardiomyopathy in children: characterisation of clinical status using tissue Doppler-derived indices of left ventricular diastolic relaxation. Heart (2006) 0.84

Intrafamilial variability for novel TAZ gene mutation: Barth syndrome with dilated cardiomyopathy and heart failure in an infant and left ventricular noncompaction in his great-uncle. Mol Genet Metab (2012) 0.84

Left ventricular aneurysm associated with isolated noncompaction of the ventricular myocardium. Heart Vessels (2006) 0.83

Left ventricular noncompaction (LVNC) and low mitochondrial membrane potential are specific for Barth syndrome. J Inherit Metab Dis (2013) 0.83

Biventricular non-compaction with predominant right ventricular involvement, reduced left ventricular systolic and diastolic function, and pulmonary hypertension in a Hispanic male. Am J Case Rep (2013) 0.82

Anomalous left coronary artery from the right sinus of valsalva and noncompaction of the left ventricle. Pediatr Cardiol (2007) 0.81

Double-orifice mitral valve associated with noncompaction of left ventricular myocardium. Pediatr Cardiol (2006) 0.81

Persistent atrial standstill in noncompaction cardiomyopathy. Pediatr Cardiol (2006) 0.81

Left ventricular noncompaction cardiomyopathy in association with trisomy 13. Pediatr Cardiol (2005) 0.80

Isolated left ventricular noncompaction in a newborn with Pierre-Robin sequence. Pediatr Cardiol (2012) 0.80

Isolated right ventricular noncompaction in a newborn. Pediatr Cardiol (2012) 0.80

Primary noncompaction of the ventricular myocardium from the morphogenetic standpoint. Pediatr Cardiol (2007) 0.80

Left ventricular non-compaction -challenges and controversies. Maedica (Buchar) (2014) 0.80

Recurrent and founder mutations in the Netherlands: mutation p.K217del in troponin T2, causing dilated cardiomyopathy. Neth Heart J (2010) 0.80

Sinus bradycardia, Wolff Parkinson White, and left ventricular noncompaction: an embryologic connection? Pediatr Cardiol (2007) 0.80

Cardiomyopathy Phenotypes and Outcomes for Children With Left Ventricular Myocardial Noncompaction: Results From the Pediatric Cardiomyopathy Registry. J Card Fail (2015) 0.80

A teenager with Marfan syndrome and left ventricular noncompaction. Pediatr Cardiol (2009) 0.80

Isolated myocardial non-compaction in an infant with distal 4q trisomy and distal 1q monosomy. Eur J Pediatr (2005) 0.79

Cardiac magnetic resonance imaging characteristics of isolated left ventricular noncompaction in a Chinese adult Han population. Int J Cardiovasc Imaging (2010) 0.79

Isolated left ventricular noncompaction causing stroke in a 30-year-old woman: case report and literature review. Tex Heart Inst J (2013) 0.79

Pediatric cardiomyopathies: causes, epidemiology, clinical course, preventive strategies and therapies. Future Cardiol (2013) 0.79

Biventricular pacing in an infant with noncompaction of the ventricular myocardium, congenital AV block, and prolonged QT interval. J Interv Card Electrophysiol (2009) 0.79

Isolated left ventricular noncompaction in a patient presenting with a subacute myocardial infarction. Neth Heart J (2007) 0.78

Isolated left ventricular noncompaction: unusual cause of decompensated heart failure and indication of heart transplantation in the early infancy--case report and literature review. Clinics (Sao Paulo) (2008) 0.78

Differing clinical courses and outcomes in two siblings with Barth syndrome and left ventricular noncompaction. Eur J Pediatr (2011) 0.78

Isolated noncompaction of myocardium associated with calcification in the interventricular septum. Pediatr Cardiol (2003) 0.77

The Impact of Concomitant Left Ventricular Non-compaction with Congenital Heart Disease on Perioperative Outcomes. Pediatr Cardiol (2016) 0.76

PLEKHM2 mutation leads to abnormal localization of lysosomes, impaired autophagy flux and associates with recessive dilated cardiomyopathy and left ventricular noncompaction. Hum Mol Genet (2015) 0.76

MIPEP recessive variants cause a syndrome of left ventricular non-compaction, hypotonia, and infantile death. Genome Med (2016) 0.76

A rare form of cardiomyopathy: left ventricular non-compaction cardiomyopathy. J Community Hosp Intern Med Perspect (2016) 0.76

Non-compaction of the ventricular myocardium. Heart Int (2006) 0.75

Echocardiography in the diagnosis left ventricular noncompaction. Cardiovasc Ultrasound (2008) 0.75

Left Ventricular Non-Compaction Syndrome Misdiagnosed as Dilated Cardiomyopathy on Several Occasions, Presenting With Recurrent Stroke. Cardiol Res (2014) 0.75

A Case of Isolated Right Ventricle Noncompaction with ST-Elevation Chest Leads. Heart Views (2016) 0.75

Noncompaction cardiomyopathy and pregnancy: An alarming coexistence ending in a favourable outcome. Exp Clin Cardiol (2012) 0.75

A rare case of heterotaxy and left ventricular non-compaction in an adult. Cardiovasc J Afr (2015) 0.75

Isolated left ventricular noncompaction diagnosed by transthoracic threedimensional echocardiography. Neth Heart J (2009) 0.75

A case of left ventricular noncompaction accompanying fasciculo-ventricular accessory pathway and atrial flutter. Korean Circ J (2012) 0.75

Focal left atrial tachycardia in a patient with left ventricular noncompaction. Case Rep Med (2013) 0.75

'Honeycomb appearance' on three-dimensional transthoracic echocardiography as the landmark of left ventricular non-compaction: two case reports. J Med Case Rep (2013) 0.75

Revisiting Non-Compaction Cardiomyopathy Through a Case with Cyanosis and Complete Heart Block. J Cardiovasc Echogr (2017) 0.75

The use of anticoagulation in pediatric cardiac disease. Images Paediatr Cardiol (2003) 0.75

Isolated Ventricular Noncompaction Cardiomyopathy Presenting as Recurrent Syncope. Case Rep Med (2016) 0.75

Biventricular Noncompaction Cardiomyopathy in an Adult with Unique Facial Dysmorphisms: Case Report and Brief Review. Case Rep Cardiol (2015) 0.75

Noncompaction Cardiomyopathy with Charcot-Marie-Tooth Disease. Case Rep Cardiol (2015) 0.75

Ventricular noncompaction in a female patient with nephropathic cystinosis: a case report. J Med Case Rep (2009) 0.75

Isolated ventricular noncompaction: a case report. Cases J (2009) 0.75

Cardiomyopathy mimicking left ventricular noncompaction in a patient with lupus nephritis. CEN Case Rep (2012) 0.75

Cardiac and neuromuscular implications of left bundle branch block in left ventricular hypertrabeculation/noncompaction. Can J Cardiol (2009) 0.75

The pathogenicity of genetic variants previously associated with left ventricular non-compaction. Mol Genet Genomic Med (2015) 0.75

Isolated left ventricular noncompaction cardiomyopathy diagnosed by transesophageal echocardiography. Clin Med Insights Cardiol (2011) 0.75

A Case of Isolated Left Ventricular Noncompaction with Basal ECG-Tracing Strongly Suggestive for Type-2 Brugada Syndrome. Cardiol Res Pract (2010) 0.75

Sinus node dysfunction as the first manifestation of left ventricular noncompaction with multiple cardiac abnormalities. Indian Pacing Electrophysiol J (2013) 0.75

Lown-Ganong-Levine syndrome in a 3-month-old infant with isolated left ventricular noncompaction. Pediatr Cardiol (2009) 0.75

Ischemic Stroke in a Young Patient Heralding a Left Ventricular Noncompaction Cardiomyopathy. Case Rep Neurol (2017) 0.75

Prolonged QTc indicates the clinical severity and poor prognosis in patients with isolated left ventricular non-compaction. Int J Cardiovasc Imaging (2017) 0.75

Non-compaction cardiomyopathy of the left ventricle diagnosed by cardiac magnetic resonance in a 2-generation family. Clin Res Cardiol (2010) 0.75

Improvement of cardiac geometry and function after cardiac resynchronization therapy for relapsed deterioration of pediatric dilated cardiomyopathy due to a noncompacted left ventricle and cardiac dyssynchrony. Pediatr Cardiol (2011) 0.75

Left Ventricular Noncompaction Cardiomyopathy in Pediatric Patients: A Case Series of a Clinically Heterogeneous Disease. Pediatr Cardiol (2017) 0.75

Articles by these authors

Life with 6000 genes. Science (1996) 41.51

The complete nucleotide sequence of the tobacco chloroplast genome: its gene organization and expression. EMBO J (1986) 19.59

Microfilaments in cellular and developmental processes. Science (1971) 13.56

Long-term lymphohematopoietic reconstitution by a single CD34-low/negative hematopoietic stem cell. Science (1996) 12.54

Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity. Proc Natl Acad Sci U S A (1993) 11.95

The [14C]deoxyglucose method for the measurement of local cerebral glucose utilization: theory, procedure, and normal values in the conscious and anesthetized albino rat. J Neurochem (1977) 11.55

The use of synthetic oligonucleotides as hybridization probes. II. Hybridization of oligonucleotides of mixed sequence to rabbit beta-globin DNA. Nucleic Acids Res (1981) 9.56

Type C virus particles in a cord T-cell line derived by co-cultivating normal human cord leukocytes and human leukaemic T cells. Nature (1981) 9.25

A novel repeated element with Z-DNA-forming potential is widely found in evolutionarily diverse eukaryotic genomes. Proc Natl Acad Sci U S A (1982) 8.15

Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues. Proc Natl Acad Sci U S A (1987) 7.38

Long-term consequences of Kawasaki disease. A 10- to 21-year follow-up study of 594 patients. Circulation (1996) 7.29

Synchronous and sequential activation of latently infected Epstein-Barr virus genomes. J Virol (1989) 5.67

The complete nucleotide sequences of the cloned hepatitis B virus DNA; subtype adr and adw. Nucleic Acids Res (1983) 5.41

Two distinct proteinase activities required for the processing of a putative nonstructural precursor protein of hepatitis C virus. J Virol (1993) 5.41

Kirsten ras mutations in patients with colorectal cancer: the 'RASCAL II' study. Br J Cancer (2001) 5.36

trans activation of the latent Epstein-Barr virus (EBV) genome after transfection of the EBV DNA fragment. J Virol (1986) 5.25

Epilepsy and exacerbation of brain injury in mice lacking the glutamate transporter GLT-1. Science (1997) 5.13

Molecular structure and evolutionary origin of human cardiac muscle actin gene. Proc Natl Acad Sci U S A (1982) 4.97

Molecular structure of the human cytoplasmic beta-actin gene: interspecies homology of sequences in the introns. Proc Natl Acad Sci U S A (1985) 4.80

Simian virus 40 (SV40) DNA replication: SV40 large T antigen unwinds DNA containing the SV40 origin of replication. Proc Natl Acad Sci U S A (1987) 4.79

A WW domain-containing yes-associated protein (YAP) is a novel transcriptional co-activator. EMBO J (1999) 4.66

Enhanced gene expression by the poly(dT-dG).poly(dC-dA) sequence. Mol Cell Biol (1984) 4.44

CDKN2/p16 or RB alterations occur in the majority of glioblastomas and are inversely correlated. Cancer Res (1996) 4.42

Potential Z-DNA forming sequences are highly dispersed in the human genome. Nature (1982) 4.41

Complete nucleotide sequence of the 16S rRNA gene of Mycobacterium bovis BCG. J Bacteriol (1988) 4.10

SCE-963, a new broad-spectrum cephalosporin: in vitro and in vivo antibacterial activities. Antimicrob Agents Chemother (1978) 4.06

Effects of environmental tobacco smoke on urinary cotinine excretion in nonsmokers. Evidence for passive smoking. N Engl J Med (1984) 3.98

A novel octamer binding transcription factor is differentially expressed in mouse embryonic cells. Cell (1990) 3.97

Replication of simian virus 40 origin-containing DNA in vitro with purified proteins. Proc Natl Acad Sci U S A (1987) 3.97

Role of DNA polymerase alpha and DNA primase in simian virus 40 DNA replication in vitro. Proc Natl Acad Sci U S A (1986) 3.85

Plexin-neuropilin-1 complexes form functional semaphorin-3A receptors. Cell (1999) 3.84

Left-right asymmetric expression of the TGF beta-family member lefty in mouse embryos. Nature (1996) 3.79

Proposal for a new clinical entity, IgG4-positive multiorgan lymphoproliferative syndrome: analysis of 64 cases of IgG4-related disorders. Ann Rheum Dis (2008) 3.77

Proteolytic processing and membrane association of putative nonstructural proteins of hepatitis C virus. Proc Natl Acad Sci U S A (1993) 3.68

Autoregulatory frameshifting in decoding mammalian ornithine decarboxylase antizyme. Cell (1995) 3.64

K-252 compounds, novel and potent inhibitors of protein kinase C and cyclic nucleotide-dependent protein kinases. Biochem Biophys Res Commun (1987) 3.46

Characterization of genomic poly(dT-dG).poly(dC-dA) sequences: structure, organization, and conformation. Mol Cell Biol (1984) 3.42

All for one and one for all: condensations and the initiation of skeletal development. Bioessays (2000) 3.40

Solid-phase synthesis of polynucleotides. II. Synthesis of polythymidylic acids by the block coupling phosphotriester method. Nucleic Acids Res (1980) 3.20

Inflammatory myoglandular polyps of the colon and rectum. A clinicopathological study of 32 pedunculated polyps, distinct from other types of polyps. Am J Surg Pathol (1992) 3.11

High-dose intravenous gammaglobulin for Kawasaki disease. Lancet (1984) 3.10

The tumor-suppressor activity of PTEN is regulated by its carboxyl-terminal region. Proc Natl Acad Sci U S A (1999) 3.10

Identification of a putative target for Rho as the serine-threonine kinase protein kinase N. Science (1996) 3.09

Comparison of diameter and perimeter methods for tumor volume calculation. J Clin Oncol (2001) 3.09

Cefmenoxime (SCE-1365), a novel broad-spectrum cephalosporin: in vitro and in vivo antibacterial activities. Antimicrob Agents Chemother (1981) 3.03

Functional role for the 170- to 180-kDa glycoprotein specific to drug-resistant tumor cells as revealed by monoclonal antibodies. Proc Natl Acad Sci U S A (1986) 2.99

Protein kinase N (PKN) and PKN-related protein rhophilin as targets of small GTPase Rho. Science (1996) 2.99

Intravenous infusion of immortalized human mesenchymal stem cells protects against injury in a cerebral ischemia model in adult rat. Exp Neurol (2005) 2.97

Antitumor effect of genetically engineered mesenchymal stem cells in a rat glioma model. Gene Ther (2004) 2.97

Wortmannin, a microbial product inhibitor of myosin light chain kinase. J Biol Chem (1992) 2.85

Purification of human erythropoietin. J Biol Chem (1977) 2.83

An Epstein-Barr virus-producer line Akata: establishment of the cell line and analysis of viral DNA. Virus Genes (1991) 2.77

Characterization of mSelB, a novel mammalian elongation factor for selenoprotein translation. EMBO J (2000) 2.72

Atomic Control of the SrTiO3 Crystal Surface. Science (1994) 2.72

Cloning and expression of cDNA for salmon growth hormone in Escherichia coli. Proc Natl Acad Sci U S A (1985) 2.70

Purification of a mouse nuclear factor that binds to both the A and B cores of the polyomavirus enhancer. J Virol (1990) 2.69

Rad52 forms ring structures and co-operates with RPA in single-strand DNA annealing. Genes Cells (1998) 2.66

One subspecies of the red junglefowl (Gallus gallus gallus) suffices as the matriarchic ancestor of all domestic breeds. Proc Natl Acad Sci U S A (1994) 2.64

lefty-1 is required for left-right determination as a regulator of lefty-2 and nodal. Cell (1998) 2.63

Abnormal nodal flow precedes situs inversus in iv and inv mice. Mol Cell (1999) 2.55

Analysis of codon usage diversity of bacterial genes with a self-organizing map (SOM): characterization of horizontally transferred genes with emphasis on the E. coli O157 genome. Gene (2001) 2.55

Principles of surgical treatment for carcinoma of the esophagus: analysis of lymph node involvement. Ann Surg (1981) 2.53

Three distinct IL-2 signaling pathways mediated by bcl-2, c-myc, and lck cooperate in hematopoietic cell proliferation. Cell (1995) 2.52

Giant Rashba-type spin splitting in bulk BiTeI. Nat Mater (2011) 2.49

ACCOMMODATION AND OTHER OPTICAL PROPERTIES OF THE EYE OF THE CAT. Br J Ophthalmol (1922) 2.48

cDNA cloning and tissue-specific expression of a novel basic helix-loop-helix/PAS factor (Arnt2) with close sequence similarity to the aryl hydrocarbon receptor nuclear translocator (Arnt). Mol Cell Biol (1996) 2.42

Activation of protein kinase C by tyrosine phosphorylation in response to H2O2. Proc Natl Acad Sci U S A (1997) 2.42

An Epstein-Barr virus (EBV)-determined nuclear antigen (EBNA5) partly encoded by the transformation-associated Bam WYH region of EBV DNA: preferential expression in lymphoblastoid cell lines. Proc Natl Acad Sci U S A (1986) 2.42

Expression cloning of a novel Gal beta (1-3/1-4) GlcNAc alpha 2,3-sialyltransferase using lectin resistance selection. J Biol Chem (1993) 2.40

TSLC1 is a tumor-suppressor gene in human non-small-cell lung cancer. Nat Genet (2001) 2.37

Pathologic and biochemical studies of juvenile parkinsonism linked to chromosome 6q. Neurology (1998) 2.37

Tissue distribution of P-glycoprotein encoded by a multidrug-resistant gene as revealed by a monoclonal antibody, MRK 16. Cancer Res (1988) 2.35

The reeler gene encodes a protein with an EGF-like motif expressed by pioneer neurons. Nat Genet (1995) 2.34

Organization of rRNA genes in Mycobacterium bovis BCG. J Bacteriol (1987) 2.33

Establishment of a human acute myeloid leukemia cell line (Kasumi-1) with 8;21 chromosome translocation. Blood (1991) 2.33

Early pathological changes in the parkinsonian brain demonstrated by diffusion tensor MRI. J Neurol Neurosurg Psychiatry (2004) 2.32

Vascular imprints of neuronal activity: relationships between the dynamics of cortical blood flow, oxygenation, and volume changes following sensory stimulation. Proc Natl Acad Sci U S A (1997) 2.28

Monophyletic origin and unique dispersal patterns of domestic fowls. Proc Natl Acad Sci U S A (1996) 2.27

The L- and R-type isozymes of rat pyruvate kinase are produced from a single gene by use of different promoters. J Biol Chem (1987) 2.25

Novel gene mutations in patients with left ventricular noncompaction or Barth syndrome. Circulation (2001) 2.24

Frequent beta-catenin mutation and cytoplasmic/nuclear accumulation in pancreatic solid-pseudopapillary neoplasm. Cancer Res (2001) 2.22

Coagulation activity is increased in the left atrium of patients with mitral stenosis. J Am Coll Cardiol (1995) 2.19

Dynamics of hepatitis C viremia following interferon-alpha administration. J Infect Dis (1998) 2.18

Organization and evolution of variable region genes of the human immunoglobulin heavy chain. J Mol Biol (1986) 2.17

Detection of epidemics in their early stage through infectious disease surveillance. Int J Epidemiol (2000) 2.17

KT5926, a potent and selective inhibitor of myosin light chain kinase. Mol Pharmacol (1990) 2.16

Species-specific in vitro synthesis of DNA containing the polyoma virus origin of replication. Proc Natl Acad Sci U S A (1986) 2.16

The nasopharyngeal bacterial flora in children with otitis media with effusion. Eur Arch Otorhinolaryngol (1996) 2.16

A rare case of bilateral supernumerary teeth in the mandibular incisors. Br Dent J (1998) 2.16

Defective stratum corneum and early neonatal death in mice lacking the gene for transglutaminase 1 (keratinocyte transglutaminase). Proc Natl Acad Sci U S A (1998) 2.12

Predominance of T lymphocytes in pancreatic islets and spleen of pre-diabetic non-obese diabetic (NOD) mice: a longitudinal study. Clin Exp Immunol (1985) 2.12

Involvement of brain-derived neurotrophic factor in spatial memory formation and maintenance in a radial arm maze test in rats. J Neurosci (2000) 2.11

Structure of a human smooth muscle actin gene (aortic type) with a unique intron site. Mol Cell Biol (1984) 2.11

The POU domain transcription factor Brn-2 is required for the determination of specific neuronal lineages in the hypothalamus of the mouse. Genes Dev (1995) 2.11

Characterization of a novel giant scaffolding protein, CG-NAP, that anchors multiple signaling enzymes to centrosome and the golgi apparatus. J Biol Chem (1999) 2.10

Betacellulin: a mitogen from pancreatic beta cell tumors. Science (1993) 2.10

Suppression of signalling through transcription factor NF-AT by interactions between calcineurin and Bcl-2. Nature (1997) 2.09

Comparative evaluation of 99mTc-MIBI and 99mTc-HMDP scintimammography for the diagnosis of breast cancer and its axillary metastases. Eur J Nucl Med (2001) 2.09

Proximal margin length with transhiatal gastrectomy for Siewert type II and III adenocarcinomas of the oesophagogastric junction. Br J Surg (2013) 2.06