Intermediate-term hematopoietic stem cells with extended but time-limited reconstitution potential.

PubWeight™: 1.87‹?› | Rank: Top 3%

🔗 View Article (PMID 20074534)

Published in Cell Stem Cell on January 08, 2010

Authors

Patricia Benveniste1, Catherine Frelin, Salima Janmohamed, Mary Barbara, Robert Herrington, Deborah Hyam, Norman N Iscove

Author Affiliations

1: Ontario Cancer Institute, Toronto, ON M5G 2M9, Canada.

Articles citing this

Distinct hematopoietic stem cell subtypes are differentially regulated by TGF-beta1. Cell Stem Cell (2010) 3.69

SLAM family markers resolve functionally distinct subpopulations of hematopoietic stem cells and multipotent progenitors. Cell Stem Cell (2013) 2.47

IL-6 controls leukemic multipotent progenitor cell fate and contributes to chronic myelogenous leukemia development. Cancer Cell (2011) 2.05

Platelet-biased stem cells reside at the apex of the haematopoietic stem-cell hierarchy. Nature (2013) 1.94

Chronic exposure to a TLR ligand injures hematopoietic stem cells. J Immunol (2011) 1.76

The Dlk1-Gtl2 Locus Preserves LT-HSC Function by Inhibiting the PI3K-mTOR Pathway to Restrict Mitochondrial Metabolism. Cell Stem Cell (2015) 1.56

HIV-1 infection of hematopoietic progenitor cells in vivo in humanized mice. Blood (2013) 1.51

CD166 regulates human and murine hematopoietic stem cells and the hematopoietic niche. Blood (2014) 1.50

GATA-3 regulates the self-renewal of long-term hematopoietic stem cells. Nat Immunol (2013) 1.19

An anticlastogenic function for the Polycomb Group gene Bmi1. Proc Natl Acad Sci U S A (2011) 1.17

Clonal tracking of rhesus macaque hematopoiesis highlights a distinct lineage origin for natural killer cells. Cell Stem Cell (2014) 1.15

Accurate expression profiling of very small cell populations. PLoS One (2010) 1.13

Analysis of the clonal growth and differentiation dynamics of primitive barcoded human cord blood cells in NSG mice. Blood (2013) 1.13

Signaling from the sympathetic nervous system regulates hematopoietic stem cell emergence during embryogenesis. Cell Stem Cell (2012) 1.11

Functional diversity of stem and progenitor cells with B-lymphopoietic potential. Immunol Rev (2010) 1.04

Mechanobiology of bone marrow stem cells: from myosin-II forces to compliance of matrix and nucleus in cell forms and fates. Differentiation (2013) 1.04

Functionally Distinct Subsets of Lineage-Biased Multipotent Progenitors Control Blood Production in Normal and Regenerative Conditions. Cell Stem Cell (2015) 1.03

Dynamics of HSPC repopulation in nonhuman primates revealed by a decade-long clonal-tracking study. Cell Stem Cell (2014) 1.02

Single-cell RNA-seq reveals changes in cell cycle and differentiation programs upon aging of hematopoietic stem cells. Genome Res (2015) 1.01

CDK6 levels regulate quiescence exit in human hematopoietic stem cells. Cell Stem Cell (2015) 1.00

Niche heterogeneity in the bone marrow. Ann N Y Acad Sci (2016) 0.96

In Vivo Tracking of Human Hematopoiesis Reveals Patterns of Clonal Dynamics during Early and Steady-State Reconstitution Phases. Cell Stem Cell (2016) 0.93

Somatic stem cell heterogeneity: diversity in the blood, skin and intestinal stem cell compartments. Nat Rev Mol Cell Biol (2015) 0.93

Clonal expansion capacity defines two consecutive developmental stages of long-term hematopoietic stem cells. J Exp Med (2014) 0.92

Hematopoiesis. Cold Spring Harb Perspect Biol (2012) 0.91

STAT5 in hematopoietic stem cell biology and transplantation. JAKSTAT (2013) 0.90

Pleiotropic effects of prostaglandin E2 in hematopoiesis; prostaglandin E2 and other eicosanoids regulate hematopoietic stem and progenitor cell function. Prostaglandins Other Lipid Mediat (2011) 0.89

Characterization of the effects of exercise training on hematopoietic stem cell quantity and function. J Appl Physiol (1985) (2012) 0.87

Mapping differentiation pathways from hematopoietic stem cells using Flk2/Flt3 lineage tracing. Cell Cycle (2012) 0.87

The role of novel and known extracellular matrix and adhesion molecules in the homeostatic and regenerative bone marrow microenvironment. Cell Adh Migr (2014) 0.87

HSC-explorer: a curated database for hematopoietic stem cells. PLoS One (2013) 0.86

Distinct stromal cell factor combinations can separately control hematopoietic stem cell survival, proliferation, and self-renewal. Cell Rep (2014) 0.84

Clonal-level responses of functionally distinct hematopoietic stem cells to trophic factors. Exp Hematol (2013) 0.81

Replenishing B lymphocytes in health and disease. Curr Opin Immunol (2012) 0.80

Control of the hematopoietic stem cell state. Cell Res (2013) 0.79

Hematopoietic and mesenchymal stem cells for the treatment of chronic respiratory diseases: role of plasticity and heterogeneity. ScientificWorldJournal (2014) 0.79

Acute lymphoblastic leukemia and developmental biology: a crucial interrelationship. Cell Cycle (2011) 0.79

Lnk adaptor suppresses radiation resistance and radiation-induced B-cell malignancies by inhibiting IL-11 signaling. Proc Natl Acad Sci U S A (2013) 0.78

Novel source of human hematopoietic stem cells from peritoneal dialysis effluents. Stem Cell Res (2015) 0.77

CD4 is expressed on a heterogeneous subset of hematopoietic progenitors, which persistently harbor CXCR4 and CCR5-tropic HIV proviral genomes in vivo. PLoS Pathog (2017) 0.77

GATA-3 controls self-renewal in stressed HSCs. Nat Immunol (2013) 0.76

Dynamic equilibrium of heterogeneous and interconvertible multipotent hematopoietic cell subsets. Sci Rep (2014) 0.76

Bridge over troubled stem cells. Mol Ther (2011) 0.75

Limited transplantation of antigen-expressing hematopoietic stem cells induces long-lasting cytotoxic T cell responses. PLoS One (2011) 0.75

Haematopoietic stem cells: past, present and future. Cell Death Discov (2017) 0.75

Stem and progenitor cell subsets are affected by JAK2 signaling and can be monitored by flow cytometry. PLoS One (2014) 0.75

Pituitary adenylate cyclase-activating polypeptide (PACAP) contributes to the proliferation of hematopoietic progenitor cells in murine bone marrow via PACAP-specific receptor. Sci Rep (2016) 0.75

Neurokinin-1 receptor signalling impacts bone marrow repopulation efficiency. PLoS One (2013) 0.75

The mammary stem cell conundrum: is it unipotent or multipotent? Breast Cancer Res (2012) 0.75

Kras is Required for Adult Hematopoiesis. Stem Cells (2016) 0.75

Articles by these authors

Hematopoietic competence is a rare property of neural stem cells that may depend on genetic and epigenetic alterations. Nat Med (2002) 3.94

Transcriptome analysis of the normal human mammary cell commitment and differentiation process. Cell Stem Cell (2008) 3.87

Representation is faithfully preserved in global cDNA amplified exponentially from sub-picogram quantities of mRNA. Nat Biotechnol (2002) 3.26

Loss of Tankyrase-mediated destruction of 3BP2 is the underlying pathogenic mechanism of cherubism. Cell (2011) 2.34

Scl regulates the quiescence and the long-term competence of hematopoietic stem cells. Blood (2009) 1.87

In vitro and in vivo expansion of hematopoietic stem cells. Oncogene (2004) 1.83

Asymmetric segregation and self-renewal of hematopoietic stem and progenitor cells with endocytic Ap2a2. Blood (2011) 1.65

Hematopoietic stem cells engraft in mice with absolute efficiency. Nat Immunol (2003) 1.55

An RNAi screen identifies Msi2 and Prox1 as having opposite roles in the regulation of hematopoietic stem cell activity. Cell Stem Cell (2010) 1.52

Essential role for Ptpn11 in survival of hematopoietic stem and progenitor cells. Blood (2011) 1.36

A novel role for STAT1 in regulating murine erythropoiesis: deletion of STAT1 results in overall reduction of erythroid progenitors and alters their distribution. Blood (2004) 1.34

Retinoic acid signaling is essential for embryonic hematopoietic stem cell development. Cell (2013) 1.25

GATA-3 regulates the self-renewal of long-term hematopoietic stem cells. Nat Immunol (2013) 1.19

Monitoring NF-kappa B transactivation potential via real-time PCR quantification of I kappa B-alpha gene expression. Mol Diagn (2003) 1.05

cDNAs generated from individual epidermal cells reveal that differential gene expression predicting subsequent resistance or susceptibility to rust fungal infection occurs prior to the fungus entering the cell lumen. Mol Plant Microbe Interact (2003) 1.02

3BP2-deficient mice are osteoporotic with impaired osteoblast and osteoclast functions. J Clin Invest (2011) 0.99

NF-kappaB inhibition triggers death of imatinib-sensitive and imatinib-resistant chronic myeloid leukemia cells including T315I Bcr-Abl mutants. Int J Cancer (2009) 0.99

Constitutive activation of STAT proteins in the HDLM-2 and L540 Hodgkin lymphoma-derived cell lines supports cell survival. Cell Signal (2005) 0.98

Identification of gene 3' ends by automated EST cluster analysis. Proc Natl Acad Sci U S A (2008) 0.97

OLIG2 (BHLHB1), a bHLH transcription factor, contributes to leukemogenesis in concert with LMO1. Cancer Res (2005) 0.92

Hoxa9 transduction induces hematopoietic stem and progenitor cell activity through direct down-regulation of geminin protein. PLoS One (2013) 0.88

Blocking NF-kappaB activation in Jurkat leukemic T cells converts the survival agent and tumor promoter PMA into an apoptotic effector. Oncogene (2002) 0.84

Targeted deletion of the tachykinin 4 gene (TAC4-/-) influences the early stages of B lymphocyte development. Blood (2010) 0.83

Distance impacts mortality in trauma patients with an intubation attempt. Prehosp Emerg Care (2008) 0.83

Microcytosis in ank/ank mice and the role of ANKH in promoting erythroid differentiation. Exp Cell Res (2007) 0.82

Unsuspected role of the brain morphogenetic gene Otx1 in hematopoiesis. Proc Natl Acad Sci U S A (2003) 0.78

Lnk adaptor suppresses radiation resistance and radiation-induced B-cell malignancies by inhibiting IL-11 signaling. Proc Natl Acad Sci U S A (2013) 0.78

Neurokinin-1 receptor signalling impacts bone marrow repopulation efficiency. PLoS One (2013) 0.75