Published in J Biol Chem on April 05, 1991
Aquaporin water channels--from atomic structure to clinical medicine. J Physiol (2002) 3.70
Isolation of the cDNA for erythrocyte integral membrane protein of 28 kilodaltons: member of an ancient channel family. Proc Natl Acad Sci U S A (1991) 3.69
CHIP28 water channels are localized in constitutively water-permeable segments of the nephron. J Cell Biol (1993) 3.50
Distribution of the aquaporin CHIP in secretory and resorptive epithelia and capillary endothelia. Proc Natl Acad Sci U S A (1993) 3.46
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Characterization of a new vacuolar membrane aquaporin sensitive to mercury at a unique site. Plant Cell (1996) 1.76
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Developmental gene expression and tissue distribution of the CHIP28 water-channel protein. Proc Natl Acad Sci U S A (1993) 1.68
Cloning, functional analysis and cell localization of a kidney proximal tubule water transporter homologous to CHIP28. J Cell Biol (1993) 1.60
Transcellular water transport in lung alveolar epithelium through mercury-sensitive water channels. Proc Natl Acad Sci U S A (1994) 1.59
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Aquaporin-1 water channel protein in lung: ontogeny, steroid-induced expression, and distribution in rat. J Clin Invest (1996) 1.46
Cloning, characterization, and chromosomal mapping of human aquaporin of collecting duct. J Clin Invest (1994) 1.45
An aquaporin-2 water channel mutant which causes autosomal dominant nephrogenic diabetes insipidus is retained in the Golgi complex. J Clin Invest (1998) 1.45
Cellular mechanisms of membrane protein folding. Nat Struct Mol Biol (2009) 1.45
Reorientation of aquaporin-1 topology during maturation in the endoplasmic reticulum. Mol Biol Cell (2000) 1.42
An impaired routing of wild-type aquaporin-2 after tetramerization with an aquaporin-2 mutant explains dominant nephrogenic diabetes insipidus. EMBO J (1999) 1.31
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The three-dimensional structure of human erythrocyte aquaporin CHIP. EMBO J (1994) 1.21
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Human red cell aquaporin CHIP. I. Molecular characterization of ABH and Colton blood group antigens. J Clin Invest (1994) 1.15
Expression of multiple water channel activities in Xenopus oocytes injected with mRNA from rat kidney. J Gen Physiol (1993) 1.14
Quantification of Aquaporin-CHIP water channel protein in microdissected renal tubules by fluorescence-based ELISA. J Clin Invest (1995) 1.13
Decreased pulmonary vascular permeability in aquaporin-1-null humans. Proc Natl Acad Sci U S A (2002) 1.13
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The zebrafish genome encodes the largest vertebrate repertoire of functional aquaporins with dual paralogy and substrate specificities similar to mammals. BMC Evol Biol (2010) 1.08
The emerging chondrocyte channelome. Front Physiol (2010) 1.08
Concurrent expression of erythroid and renal aquaporin CHIP and appearance of water channel activity in perinatal rats. J Clin Invest (1993) 1.06
Reversed polarized delivery of an aquaporin-2 mutant causes dominant nephrogenic diabetes insipidus. J Cell Biol (2003) 1.05
Biogenesis and transmembrane topology of the CHIP28 water channel at the endoplasmic reticulum. J Cell Biol (1994) 1.02
Membrane dynamics of the water transport protein aquaporin-1 in intact human red cells. Biophys J (1999) 0.97
Expression and immunolocalization of water-channel aquaporins in the rat and mouse mammary gland. Histochem Cell Biol (2005) 0.97
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Apical endosomes isolated from kidney collecting duct principal cells lack subunits of the proton pumping ATPase. J Cell Biol (1992) 0.93
Structure and stability of the spinach aquaporin SoPIP2;1 in detergent micelles and lipid membranes. PLoS One (2011) 0.92
Aquaporins as gas channels. Pflugers Arch (2011) 0.92
Human red cell Aquaporin CHIP. II. Expression during normal fetal development and in a novel form of congenital dyserythropoietic anemia. J Clin Invest (1994) 0.90
Membrane-associated aquaporin-1 facilitates osmotically driven water flux across the basolateral membrane of the thick ascending limb. Am J Physiol Renal Physiol (2012) 0.87
3D imaging and quantitative analysis of small solubilized membrane proteins and their complexes by transmission electron microscopy. Microscopy (Oxf) (2012) 0.87
Secondary structures comparison of aquaporin-1 and bacteriorhodopsin: a Fourier transform infrared spectroscopy study of two-dimensional membrane crystals. Biophys J (1997) 0.86
Intact and N- or C-terminal end truncated AQP0 function as open water channels and cell-to-cell adhesion proteins: end truncation could be a prelude for adjusting the refractive index of the lens to prevent spherical aberration. Biochim Biophys Acta (2014) 0.85
Functional characterization of an AQP0 missense mutation, R33C, that causes dominant congenital lens cataract, reveals impaired cell-to-cell adhesion. Exp Eye Res (2013) 0.84
Lentil seed aquaporins form a hetero-oligomer which is phosphorylated by a Mg(2+)-dependent and Ca(2+)-regulated kinase. Biochem J (2000) 0.83
Expression and localization of aquaporin-1 on the apical membrane of enterocytes in the small intestine of bottlenose dolphins. J Comp Physiol B (2009) 0.83
A Minireview on Vasopressin-regulated Aquaporin-2 in Kidney Collecting Duct Cells. Electrolyte Blood Press (2015) 0.82
Yeast Fps1 glycerol facilitator functions as a homotetramer. Yeast (2011) 0.81
Localization of aquaporin-2, renal morphology and urine composition in the bottlenose dolphin and the Baird's beaked whale. J Comp Physiol B (2007) 0.81
Induced expression and functional effects of aquaporin-1 in human leukocytes in sepsis. Crit Care (2013) 0.80
Membrane protein dynamics and functional implications in mammalian cells. Curr Top Membr (2013) 0.79
Regulation of aquaporin-2 in the kidney: A molecular mechanism of body-water homeostasis. Kidney Res Clin Pract (2013) 0.78
Molecular dynamics of water in the neighborhood of aquaporins. Eur Biophys J (2012) 0.77
Role of aquaporins and regulation of secretory vesicle volume in cell secretion. J Cell Mol Med (2008) 0.76
Maintenance of Transcription-Translation Coupling by Elongation Factor P. MBio (2016) 0.76
Large Pore Ion and Metabolite-Permeable Channel Regulation of Postnatal Ventricular Zone Neural Stem and Progenitor Cells: Interplay between Aquaporins, Connexins, and Pannexins? Stem Cells Int (2012) 0.75
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In Vitro Protective Effect of Phikud Navakot Extraction on Erythrocyte. Evid Based Complement Alternat Med (2016) 0.75
From membrane pores to aquaporins: 50 years measuring water fluxes. J Biol Phys (2008) 0.75
Aspergillus glaucus Aquaglyceroporin Gene glpF Confers High Osmosis Tolerance in Heterologous Organisms. Appl Environ Microbiol (2015) 0.75
Rgc2 Regulator of Glycerol Channel Fps1 Functions as a Homo- and Heterodimer with Rgc1. Eukaryot Cell (2015) 0.75
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Changes observed in erythrocyte cells exposed to an alternating current. Clujul Med (2017) 0.75
Aquaporins in the honeybee crop--a new function for an old organ. Protoplasma (2014) 0.75
Appearance of water channels in Xenopus oocytes expressing red cell CHIP28 protein. Science (1992) 9.09
Structural determinants of water permeation through aquaporin-1. Nature (2000) 7.66
Specialized membrane domains for water transport in glial cells: high-resolution immunogold cytochemistry of aquaporin-4 in rat brain. J Neurosci (1997) 5.68
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Identification, purification, and partial characterization of a novel Mr 28,000 integral membrane protein from erythrocytes and renal tubules. J Biol Chem (1988) 3.83
The mercury-sensitive residue at cysteine 189 in the CHIP28 water channel. J Biol Chem (1993) 3.80
Isolation of the cDNA for erythrocyte integral membrane protein of 28 kilodaltons: member of an ancient channel family. Proc Natl Acad Sci U S A (1991) 3.69
Cellular and molecular biology of the aquaporin water channels. Annu Rev Biochem (1999) 3.65
CHIP28 water channels are localized in constitutively water-permeable segments of the nephron. J Cell Biol (1993) 3.50
Distribution of the aquaporin CHIP in secretory and resorptive epithelia and capillary endothelia. Proc Natl Acad Sci U S A (1993) 3.46
Molecular characterization of an aquaporin cDNA from brain: candidate osmoreceptor and regulator of water balance. Proc Natl Acad Sci U S A (1994) 3.20
Direct immunogold labeling of aquaporin-4 in square arrays of astrocyte and ependymocyte plasma membranes in rat brain and spinal cord. Proc Natl Acad Sci U S A (1998) 2.99
Syntrophin-dependent expression and localization of Aquaporin-4 water channel protein. Proc Natl Acad Sci U S A (2001) 2.88
Molecular structure of the water channel through aquaporin CHIP. The hourglass model. J Biol Chem (1994) 2.65
Reconstitution and functional comparison of purified GlpF and AqpZ, the glycerol and water channels from Escherichia coli. Proc Natl Acad Sci U S A (2001) 2.28
The three-dimensional structure of aquaporin-1. Nature (1997) 2.28
Pathophysiology of the aquaporin water channels. Annu Rev Physiol (1996) 2.25
Aquaporins: water channel proteins of plant and animal cells. Trends Biochem Sci (1994) 2.22
Rapid gating and anion permeability of an intracellular aquaporin. Nature (1999) 2.17
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Defective cellular trafficking of lacrimal gland aquaporin-5 in Sjögren's syndrome. Lancet (2001) 2.10
Mutations in aquaporin-1 in phenotypically normal humans without functional CHIP water channels. Science (1994) 2.09
Heterotetrameric composition of aquaporin-4 water channels. Biochemistry (1999) 2.05
Molecular cloning and characterization of an aquaporin cDNA from salivary, lacrimal, and respiratory tissues. J Biol Chem (1995) 2.02
Functional reconstitution and characterization of AqpZ, the E. coli water channel protein. J Mol Biol (1999) 1.99
Partial deficiency of erythrocyte spectrin in hereditary spherocytosis. Nature (1985) 1.81
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Increased fluid secretion after adenoviral-mediated transfer of the aquaporin-1 cDNA to irradiated rat salivary glands. Proc Natl Acad Sci U S A (1997) 1.76
Reductions of erythrocyte membrane viscoelastic coefficients reflect spectrin deficiencies in hereditary spherocytosis. J Clin Invest (1988) 1.75
Functional impairment of lens aquaporin in two families with dominantly inherited cataracts. Hum Mol Genet (2000) 1.73
Developmental gene expression and tissue distribution of the CHIP28 water-channel protein. Proc Natl Acad Sci U S A (1993) 1.68
Water channel properties of major intrinsic protein of lens. J Biol Chem (1995) 1.64
Aquaporin-1 water channels in short and long loop descending thin limbs and in descending vasa recta in rat kidney. Am J Physiol (1995) 1.59
Aquaporins in complex tissues: distribution of aquaporins 1-5 in human and rat eye. Am J Physiol (1998) 1.59
Keratinocyte growth factor modulates alveolar epithelial cell phenotype in vitro: expression of aquaporin 5. Am J Respir Cell Mol Biol (1998) 1.59
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Membrane topology of aquaporin CHIP. Analysis of functional epitope-scanning mutants by vectorial proteolysis. J Biol Chem (1994) 1.47
Aquaporin-1 water channel protein in lung: ontogeny, steroid-induced expression, and distribution in rat. J Clin Invest (1996) 1.46
Biologically active two-dimensional crystals of aquaporin CHIP. J Biol Chem (1994) 1.45
Linkage of dominant hereditary spherocytosis to the gene for the erythrocyte membrane-skeleton protein ankyrin. N Engl J Med (1990) 1.45
Ultrastructure, pharmacologic inhibition, and transport selectivity of aquaporin channel-forming integral protein in proteoliposomes. Biochemistry (1994) 1.44
Two-dimensional iodopeptide mapping demonstrates that erythrocyte Rh D, c, and E polypeptides are structurally homologous but nonidentical. Blood (1988) 1.42
Highly selective water channel activity measured by voltage clamp: analysis of planar lipid bilayers reconstituted with purified AqpZ. Proc Natl Acad Sci U S A (2001) 1.42
Abnormal distribution of aquaporin-5 water channel protein in salivary glands from Sjögren's syndrome patients. Lab Invest (2001) 1.40
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High resolution AFM topographs of the Escherichia coli water channel aquaporin Z. EMBO J (1999) 1.34
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Defective urinary-concentrating ability due to a complete deficiency of aquaporin-1. N Engl J Med (2001) 1.29
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Functional analysis of aquaporin-1 deficient red cells. The Colton-null phenotype. J Biol Chem (1996) 1.26
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Inheritance pattern and clinical response to splenectomy as a reflection of erythrocyte spectrin deficiency in hereditary spherocytosis. N Engl J Med (1986) 1.24
Altered ubiquitination and stability of aquaporin-1 in hypertonic stress. Proc Natl Acad Sci U S A (2001) 1.24
The human aquaporin-CHIP gene. Structure, organization, and chromosomal localization. J Biol Chem (1993) 1.23
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Regulation of the Escherichia coli water channel gene aqpZ. Proc Natl Acad Sci U S A (1998) 1.22
The aquaporin family of water channels in kidney. Kidney Int (1995) 1.22
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Ontogeny of water transport in rat brain: postnatal expression of the aquaporin-4 water channel. Eur J Neurosci (1999) 1.20
Water and ion permeation of aquaporin-1 in planar lipid bilayers. Major differences in structural determinants and stoichiometry. J Biol Chem (2001) 1.19
Hypertonic induction of aquaporin-5 expression through an ERK-dependent pathway. J Biol Chem (2000) 1.19
The importance of aquaporin water channel protein structures. EMBO J (2000) 1.18
Human red cell aquaporin CHIP. I. Molecular characterization of ABH and Colton blood group antigens. J Clin Invest (1994) 1.15
Secretin induces the apical insertion of aquaporin-1 water channels in rat cholangiocytes. Am J Physiol (1999) 1.15
Expression of multiple water channel activities in Xenopus oocytes injected with mRNA from rat kidney. J Gen Physiol (1993) 1.14
Quantification of Aquaporin-CHIP water channel protein in microdissected renal tubules by fluorescence-based ELISA. J Clin Invest (1995) 1.13
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Alteration of the erythrocyte membrane skeletal ultrastructure in hereditary spherocytosis, hereditary elliptocytosis, and pyropoikilocytosis. Blood (1990) 1.09
Evidence that aquaporin-1 mediates NaCl-induced water flux across descending vasa recta. Am J Physiol (1997) 1.08
Surface topographies at subnanometer-resolution reveal asymmetry and sidedness of aquaporin-1. J Mol Biol (1996) 1.08
Sequence and exon-intron organization of the DNA encoding the alpha I domain of human spectrin. Application to the study of mutations causing hereditary elliptocytosis. J Clin Invest (1989) 1.08
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Adenovirus-mediated expression of aquaporin-5 in epithelial cells. J Biol Chem (1996) 1.06
Progress on the structure and function of aquaporin 1. J Struct Biol (1998) 1.06
Concurrent expression of erythroid and renal aquaporin CHIP and appearance of water channel activity in perinatal rats. J Clin Invest (1993) 1.06
The mouse aquaporin-1 gene. Genomics (1995) 1.05
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Cholangiocytes express the aquaporin CHIP and transport water via a channel-mediated mechanism. Proc Natl Acad Sci U S A (1994) 0.99
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