Published in Bing Du Xue Bao on November 01, 2009
Evolutionary and biomedical insights from the rhesus macaque genome. Science (2007) 16.21
RAS mutations in cutaneous squamous-cell carcinomas in patients treated with BRAF inhibitors. N Engl J Med (2012) 6.93
Principles for characterizing the potential human health effects from exposure to nanomaterials: elements of a screening strategy. Part Fibre Toxicol (2005) 6.04
Effect of iodine intake on thyroid diseases in China. N Engl J Med (2006) 5.46
Assessing agricultural risks of climate change in the 21st century in a global gridded crop model intercomparison. Proc Natl Acad Sci U S A (2013) 5.43
Thiazolidinone CFTR inhibitor identified by high-throughput screening blocks cholera toxin-induced intestinal fluid secretion. J Clin Invest (2002) 4.97
Genome sequence of Shigella flexneri 2a: insights into pathogenicity through comparison with genomes of Escherichia coli K12 and O157. Nucleic Acids Res (2002) 4.92
An outbreak of hand, foot, and mouth disease associated with subgenotype C4 of human enterovirus 71 in Shandong, China. J Clin Virol (2009) 4.62
A high-resolution assessment on global nitrogen flows in cropland. Proc Natl Acad Sci U S A (2010) 4.08
Comparison of the World Health Organization (WHO) Child Growth Standards and the National Center for Health Statistics/WHO international growth reference: implications for child health programmes. Public Health Nutr (2006) 3.84
Genetic characteristics of human enterovirus 71 and coxsackievirus A16 circulating from 1999 to 2004 in Shenzhen, People's Republic of China. J Clin Microbiol (2005) 3.82
Uncovering intrinsic modular organization of spontaneous brain activity in humans. PLoS One (2009) 3.43
R gene expression induced by a type-III effector triggers disease resistance in rice. Nature (2005) 3.25
The complete genome sequence of Chlorobium tepidum TLS, a photosynthetic, anaerobic, green-sulfur bacterium. Proc Natl Acad Sci U S A (2002) 3.19
Phase I trial of the proteasome inhibitor bortezomib in patients with advanced solid tumors with observations in androgen-independent prostate cancer. J Clin Oncol (2004) 3.02
Enterovirus 71 outbreak in the People's Republic of China in 2008. J Clin Microbiol (2009) 2.98
Parcellation-dependent small-world brain functional networks: a resting-state fMRI study. Hum Brain Mapp (2009) 2.91
Nitrogen fixation island and rhizosphere competence traits in the genome of root-associated Pseudomonas stutzeri A1501. Proc Natl Acad Sci U S A (2008) 2.70
A genome-wide study identifies HLA alleles associated with lumiracoxib-related liver injury. Nat Genet (2010) 2.68
Identification and control of a poliomyelitis outbreak in Xinjiang, China. N Engl J Med (2013) 2.55
Why are babies getting bigger? Temporal trends in fetal growth and its determinants. J Pediatr (2002) 2.47
Phosphorylation of p53 on key serines is dispensable for transcriptional activation and apoptosis. J Biol Chem (2004) 2.46
Spatial analysis of hemorrhagic fever with renal syndrome in China. BMC Infect Dis (2006) 2.42
Facilitation of μ-opioid receptor activity by preventing δ-opioid receptor-mediated codegradation. Neuron (2011) 2.42
Genetic association of FOXO1A and FOXO3A with longevity trait in Han Chinese populations. Hum Mol Genet (2009) 2.34
Virome analysis for identification of novel mammalian viruses in bat species from Chinese provinces. J Virol (2012) 2.21
Human cytomegalovirus escapes a naturally occurring neutralizing antibody by incorporating it into assembling virions. Cell Host Microbe (2011) 2.20
d+id' chiral superconductivity in bilayer silicene. Phys Rev Lett (2013) 2.18
Muscle-specific knockout of PKC-lambda impairs glucose transport and induces metabolic and diabetic syndromes. J Clin Invest (2007) 2.17
Testing the position-effect variegation hypothesis for facioscapulohumeral muscular dystrophy by analysis of histone modification and gene expression in subtelomeric 4q. Hum Mol Genet (2003) 2.15
Combinatorial therapy with neurotrophins and cAMP promotes axonal regeneration beyond sites of spinal cord injury. J Neurosci (2004) 2.14
Environmental factors contributing to the spread of H5N1 avian influenza in mainland China. PLoS One (2008) 2.14
Activation of p53 by MDM2 antagonists can protect proliferating cells from mitotic inhibitors. Cancer Res (2005) 2.07
Inhibition of respiratory syncytial virus infection with intranasal siRNA nanoparticles targeting the viral NS1 gene. Nat Med (2004) 2.06
Default mode network as revealed with multiple methods for resting-state functional MRI analysis. J Neurosci Methods (2008) 2.01
Distinct roles for CREB-binding protein and p300 in hematopoietic stem cell self-renewal. Proc Natl Acad Sci U S A (2002) 1.99
Hyperhomocysteinemia decreases circulating high-density lipoprotein by inhibiting apolipoprotein A-I Protein synthesis and enhancing HDL cholesterol clearance. Circ Res (2006) 1.95
Abnormalities in cartilage and bone development in the Apert syndrome FGFR2(+/S252W) mouse. Development (2005) 1.93
Spatial analysis of malaria in Anhui province, China. Malar J (2008) 1.92
High-affinity activators of cystic fibrosis transmembrane conductance regulator (CFTR) chloride conductance identified by high-throughput screening. J Biol Chem (2002) 1.89
Ex vivo fucosylation improves human cord blood engraftment in NOD-SCID IL-2Rγ(null) mice. Exp Hematol (2012) 1.85
Quantitative estimate of the risks and benefits of possible alternative blood donor deferral strategies for men who have had sex with men. Transfusion (2009) 1.85
Registration artifacts in international comparisons of infant mortality. Paediatr Perinat Epidemiol (2002) 1.84
Spatio-temporal distribution of malaria in Yunnan Province, China. Am J Trop Med Hyg (2009) 1.81
Gray matter density and white matter integrity in pianists' brain: a combined structural and diffusion tensor MRI study. Neurosci Lett (2008) 1.79
Glut-1 deficiency syndrome: clinical, genetic, and therapeutic aspects. Ann Neurol (2005) 1.77
Genome-wide identification of PAX3-FKHR binding sites in rhabdomyosarcoma reveals candidate target genes important for development and cancer. Cancer Res (2010) 1.74
Imatinib (ST1571) provides only limited selectivity for CML cells and treatment might be complicated by silent BCR-ABL genes. Cancer Biol Ther (2003) 1.73
Resistance to selective BRAF inhibition can be mediated by modest upstream pathway activation. Cancer Res (2011) 1.73
Complete genome analysis of coxsackievirus A2, A4, A5, and A10 strains isolated from hand, foot, and mouth disease patients in China revealing frequent recombination of human enterovirus A. J Clin Microbiol (2011) 1.71
Thermosensitive TRPV channel subunits coassemble into heteromeric channels with intermediate conductance and gating properties. J Gen Physiol (2007) 1.68
Structure-guided design of a selective BCL-X(L) inhibitor. Nat Chem Biol (2013) 1.68
MEK-independent survival of B-RAFV600E melanoma cells selected for resistance to apoptosis induced by the RAF inhibitor PLX4720. Clin Cancer Res (2010) 1.68
The cancer/testis antigen prostate-associated gene 4 (PAGE4) is a highly intrinsically disordered protein. J Biol Chem (2011) 1.68
Quantitative analysis of HBV DNA level and HBeAg titer in hepatitis B surface antigen positive mothers and their babies: HBeAg passage through the placenta and the rate of decay in babies. J Med Virol (2003) 1.63
Genes that escape from X inactivation. Hum Genet (2011) 1.63
A mouse model for Glut-1 haploinsufficiency. Hum Mol Genet (2006) 1.63
Lipid interaction converts prion protein to a PrPSc-like proteinase K-resistant conformation under physiological conditions. Biochemistry (2007) 1.62
A Xanthomonas uridine 5'-monophosphate transferase inhibits plant immune kinases. Nature (2012) 1.60
Statistical modeling of global geogenic arsenic contamination in groundwater. Environ Sci Technol (2008) 1.60
Climate variability and hemorrhagic fever with renal syndrome transmission in Northeastern China. Environ Health Perspect (2010) 1.59
Hyperhomocysteinemia accelerates atherosclerosis in cystathionine beta-synthase and apolipoprotein E double knock-out mice with and without dietary perturbation. Blood (2002) 1.59
Characterization of ST-4821 complex, a unique Neisseria meningitidis clone. Genomics (2007) 1.59
Video-assisted thoracoscopic left cardiac sympathetic denervation: a reliable minimally invasive approach for congenital long-QT syndrome. Ann Thorac Surg (2008) 1.58
Rhesus monkey trace amine-associated receptor 1 signaling: enhancement by monoamine transporters and attenuation by the D2 autoreceptor in vitro. J Pharmacol Exp Ther (2007) 1.57
Survival and risk factors of surgically treated mediastinal invasion T4 non-small cell lung cancer. Ann Thorac Surg (2009) 1.56
Active localization of the retinoblastoma protein in chromatin and its response to S phase DNA damage. Mol Cell (2003) 1.55
Hierarchical MnMoO(4)/CoMoO(4) heterostructured nanowires with enhanced supercapacitor performance. Nat Commun (2011) 1.55
Revisiting the molecular evolutionary history of Shigella spp. J Mol Evol (2006) 1.54
Complete genome sequence of Shigella flexneri 5b and comparison with Shigella flexneri 2a. BMC Genomics (2006) 1.54
The future of biologic coatings for orthopaedic implants. Biomaterials (2013) 1.53
Circulation of Coxsackievirus A10 and A6 in hand-foot-mouth disease in China, 2009-2011. PLoS One (2012) 1.52
Hyperhomocystinemia impairs endothelial function and eNOS activity via PKC activation. Arterioscler Thromb Vasc Biol (2005) 1.52
{μ-6,6'-Dimeth-oxy-2,2'-[cyclo-hexane-1,2-diylbis(nitrilo-methyl-idyne)]diphenolato}methanol-μ-nitrato-dinitratocopper(II)europium(III). Acta Crystallogr Sect E Struct Rep Online (2010) 1.51
Emergence, circulation, and spatiotemporal phylogenetic analysis of coxsackievirus a6- and coxsackievirus a10-associated hand, foot, and mouth disease infections from 2008 to 2012 in Shenzhen, China. J Clin Microbiol (2013) 1.50
Stabilizing the pro-apoptotic BimBH3 helix (BimSAHB) does not necessarily enhance affinity or biological activity. ACS Chem Biol (2012) 1.50
Echocardiographic left ventricular mass in a multiethnic Southeast Asian population: proposed new gender and age-specific norms. Echocardiography (2008) 1.48
An N-terminal region of translationally controlled tumor protein is required for its antiapoptotic activity. Oncogene (2005) 1.47
Human bocavirus in children suffering from acute lower respiratory tract infection in Beijing Children's Hospital. Chin Med J (Engl) (2008) 1.47
Global assessment of exposure to faecal contamination through drinking water based on a systematic review. Trop Med Int Health (2014) 1.46
Positive transforming growth factor-β activated kinase-1 expression has an unfavorable impact on survival in T3N1-3M0 esophageal squamous cell carcinomas. Ann Thorac Surg (2012) 1.46
Dietary restriction reduces atherosclerosis and oxidative stress in the aorta of apolipoprotein E-deficient mice. Mech Ageing Dev (2002) 1.46
BIK1 interacts with PEPRs to mediate ethylene-induced immunity. Proc Natl Acad Sci U S A (2013) 1.45
Dormancy cycling and persistence of seeds in soil of a cold desert halophyte shrub. Ann Bot (2013) 1.44
Spatiotemporal trends and climatic factors of hemorrhagic fever with renal syndrome epidemic in Shandong Province, China. PLoS Negl Trop Dis (2010) 1.43
Identification of natural coumarin compounds that rescue defective DeltaF508-CFTR chloride channel gating. Clin Exp Pharmacol Physiol (2008) 1.43
Recombinant human hepassocin stimulates proliferation of hepatocytes in vivo and improves survival in rats with fulminant hepatic failure. Gut (2009) 1.43
CXCR2 promotes ovarian cancer growth through dysregulated cell cycle, diminished apoptosis, and enhanced angiogenesis. Clin Cancer Res (2010) 1.42
Unbiased parallel detection of viral pathogens in clinical samples by use of a metagenomic approach. J Clin Microbiol (2011) 1.41
"Endomicrobia": cytoplasmic symbionts of termite gut protozoa form a separate phylum of prokaryotes. Appl Environ Microbiol (2005) 1.41
Climate change and mercury accumulation in Canadian high and subarctic lakes. Environ Sci Technol (2011) 1.39
Using a standardized follow-up program to improve coronary heart disease secondary prevention. Anatol J Cardiol (2015) 1.39
Escape from X inactivation in mice and humans. Genome Biol (2010) 1.39
Uric acid, hyperuricemia and vascular diseases. Front Biosci (Landmark Ed) (2012) 1.38
Comparison of epidermal growth factor receptor mutation statuses in tissue and plasma in stage I-IV non-small cell lung cancer patients. Respiration (2012) 1.38
Global distribution of rubella virus genotypes. Emerg Infect Dis (2003) 1.36