Published in Acta Biomater on January 18, 2010
Strategies for controlled delivery of growth factors and cells for bone regeneration. Adv Drug Deliv Rev (2012) 1.57
Modeling Ewing sarcoma tumors in vitro with 3D scaffolds. Proc Natl Acad Sci U S A (2013) 1.23
Bioactive polymer/extracellular matrix scaffolds fabricated with a flow perfusion bioreactor for cartilage tissue engineering. Biomaterials (2010) 1.16
Polymeric nanofibers in tissue engineering. Tissue Eng Part B Rev (2011) 1.03
Design of experiments approach to engineer cell-secreted matrices for directing osteogenic differentiation. Ann Biomed Eng (2010) 1.02
Thermoresponsive, in situ cross-linkable hydrogels based on N-isopropylacrylamide: fabrication, characterization and mesenchymal stem cell encapsulation. Acta Biomater (2010) 1.00
Mechanical improvements to reinforced porous silk scaffolds. J Biomed Mater Res A (2011) 0.97
Cell-derived matrices for tissue engineering and regenerative medicine applications. Biomater Sci (2015) 0.92
Design of a high-throughput flow perfusion bioreactor system for tissue engineering. Tissue Eng Part C Methods (2012) 0.91
Protein and mineral composition of osteogenic extracellular matrix constructs generated with a flow perfusion bioreactor. Biomacromolecules (2011) 0.87
Bioreactor strategy in bone tissue engineering: pre-culture and osteogenic differentiation under two flow configurations. Tissue Eng Part A (2012) 0.85
Investigating the role of hematopoietic stem and progenitor cells in regulating the osteogenic differentiation of mesenchymal stem cells in vitro. J Orthop Res (2011) 0.85
Building bridges: leveraging interdisciplinary collaborations in the development of biomaterials to meet clinical needs. Adv Mater (2012) 0.84
Direct and indirect co-culture of chondrocytes and mesenchymal stem cells for the generation of polymer/extracellular matrix hybrid constructs. Acta Biomater (2013) 0.84
Enhanced osteogenesis in cocultures with human mesenchymal stem cells and endothelial cells on polymeric microfiber scaffolds. Tissue Eng Part A (2013) 0.82
Flow perfusion co-culture of human mesenchymal stem cells and endothelial cells on biodegradable polymer scaffolds. Ann Biomed Eng (2013) 0.82
Student Award for Outstanding Research Winner in the Ph.D. Category for the 9th World Biomaterials Congress, Chengdu, China, June 1-5, 2012: The interplay of bone-like extracellular matrix and TNF-α signaling on in vitro osteogenic differentiation of mesenchymal stem cells. J Biomed Mater Res A (2012) 0.79
3D tissue-engineered model of Ewing's sarcoma. Adv Drug Deliv Rev (2014) 0.79
Macro and microfluidic flows for skeletal regenerative medicine. Cells (2012) 0.79
Decellularized ECM effects on human mesenchymal stem cell stemness and differentiation. Differentiation (2015) 0.78
Thin-layer hydroxyapatite deposition on a nanofiber surface stimulates mesenchymal stem cell proliferation and their differentiation into osteoblasts. J Biomed Biotechnol (2012) 0.78
Multifunctional aliphatic polyester nanofibers for tissue engineering. Biomatter (2013) 0.75
Sustained delivery of recombinant human bone morphogenetic protein-2 from perlecan domain I - functionalized electrospun poly (ε-caprolactone) scaffolds for bone regeneration. J Exp Orthop (2016) 0.75
Osteogenic Differentiation and Mineralization on Compact Multilayer nHA-PCL Electrospun Scaffolds in a Perfusion Bioreactor. Iran J Biotechnol (2016) 0.75
Improved quantitation and discrimination of sulphated glycosaminoglycans by use of dimethylmethylene blue. Biochim Biophys Acta (1986) 13.69
Determination of hydroxyproline. Clin Chim Acta (1967) 7.28
The control of human mesenchymal cell differentiation using nanoscale symmetry and disorder. Nat Mater (2007) 6.86
Characterization of PicoGreen reagent and development of a fluorescence-based solution assay for double-stranded DNA quantitation. Anal Biochem (1997) 4.58
Progressive development of the rat osteoblast phenotype in vitro: reciprocal relationships in expression of genes associated with osteoblast proliferation and differentiation during formation of the bone extracellular matrix. J Cell Physiol (1990) 4.27
Electrospun poly(epsilon-caprolactone) microfiber and multilayer nanofiber/microfiber scaffolds: characterization of scaffolds and measurement of cellular infiltration. Biomacromolecules (2006) 3.01
Bone formation in vitro by stromal cells obtained from bone marrow of young adult rats. Cell Tissue Res (1988) 2.74
Mineralized matrix deposition by marrow stromal osteoblasts in 3D perfusion culture increases with increasing fluid shear forces. Proc Natl Acad Sci U S A (2003) 2.42
Bioreactor cultivation conditions modulate the composition and mechanical properties of tissue-engineered cartilage. J Orthop Res (1999) 2.19
Multilineage differentiation of human mesenchymal stem cells in a three-dimensional nanofibrous scaffold. Biomaterials (2005) 2.18
In vitro generated extracellular matrix and fluid shear stress synergistically enhance 3D osteoblastic differentiation. Proc Natl Acad Sci U S A (2006) 2.03
Effect of bone extracellular matrix synthesized in vitro on the osteoblastic differentiation of marrow stromal cells. Biomaterials (2005) 1.85
Design of a flow perfusion bioreactor system for bone tissue-engineering applications. Tissue Eng (2003) 1.79
Injectable biodegradable hydrogel composites for rabbit marrow mesenchymal stem cell and growth factor delivery for cartilage tissue engineering. Biomaterials (2007) 1.78
Dose effect of dual delivery of vascular endothelial growth factor and bone morphogenetic protein-2 on bone regeneration in a rat critical-size defect model. Tissue Eng Part A (2009) 1.67
Flow perfusion culture induces the osteoblastic differentiation of marrow stroma cell-scaffold constructs in the absence of dexamethasone. J Biomed Mater Res A (2005) 1.61
Pre-culture period of mesenchymal stem cells in osteogenic media influences their in vivo bone forming potential. J Biomed Mater Res A (2007) 1.34
Flow perfusion enhances the calcified matrix deposition of marrow stromal cells in biodegradable nonwoven fiber mesh scaffolds. Ann Biomed Eng (2005) 1.29
Effect of flow perfusion on the osteogenic differentiation of bone marrow stromal cells cultured on starch-based three-dimensional scaffolds. J Biomed Mater Res A (2003) 1.20
In vitro localization of bone growth factors in constructs of biodegradable scaffolds seeded with marrow stromal cells and cultured in a flow perfusion bioreactor. Tissue Eng (2006) 1.15
Flow perfusion culture of marrow stromal osteoblasts in titanium fiber mesh. J Biomed Mater Res A (2003) 1.09
Influence of the in vitro culture period on the in vivo performance of cell/titanium bone tissue-engineered constructs using a rat cranial critical size defect model. J Biomed Mater Res A (2003) 1.08
Scaffold mesh size affects the osteoblastic differentiation of seeded marrow stromal cells cultured in a flow perfusion bioreactor. J Biomed Mater Res A (2005) 1.06
A review of bone substitutes. Oral Maxillofac Surg Clin North Am (2007) 1.06
Genomic expression of mesenchymal stem cells to altered nanoscale topographies. J R Soc Interface (2008) 1.03
Differences in dermal analogs influence subsequent pigmentation, epidermal differentiation, basement membrane, and rete ridge formation of transplanted composite skin grafts. Transplantation (1997) 0.98
Modulation of cell differentiation in bone tissue engineering constructs cultured in a bioreactor. Adv Exp Med Biol (2006) 0.84
In vitro attachment of osteoblast-like cells to osteoceramic materials. Dent Mater (1997) 0.84
Electrospinning of polymeric nanofibers for tissue engineering applications: a review. Tissue Eng (2006) 4.53
Electrospun poly(epsilon-caprolactone) microfiber and multilayer nanofiber/microfiber scaffolds: characterization of scaffolds and measurement of cellular infiltration. Biomacromolecules (2006) 3.01
Biomimetic materials for tissue engineering. Biomaterials (2003) 2.87
Strategic directions in tissue engineering. Tissue Eng (2007) 2.70
Mineralized matrix deposition by marrow stromal osteoblasts in 3D perfusion culture increases with increasing fluid shear forces. Proc Natl Acad Sci U S A (2003) 2.42
Gelatin as a delivery vehicle for the controlled release of bioactive molecules. J Control Release (2005) 2.32
Thermoresponsive hydrogels in biomedical applications. Eur J Pharm Biopharm (2007) 2.25
Fluid flow increases mineralized matrix deposition in 3D perfusion culture of marrow stromal osteoblasts in a dose-dependent manner. Proc Natl Acad Sci U S A (2002) 2.24
Dual delivery of an angiogenic and an osteogenic growth factor for bone regeneration in a critical size defect model. Bone (2008) 2.19
In vitro generated extracellular matrix and fluid shear stress synergistically enhance 3D osteoblastic differentiation. Proc Natl Acad Sci U S A (2006) 2.03
Donor age and cell passage affects differentiation potential of murine bone marrow-derived stem cells. BMC Cell Biol (2008) 2.00
Injectable matrices and scaffolds for drug delivery in tissue engineering. Adv Drug Deliv Rev (2007) 1.97
Modulation of the inflammatory response for enhanced bone tissue regeneration. Tissue Eng Part B Rev (2008) 1.92
Tissue engineering of bone: material and matrix considerations. J Bone Joint Surg Am (2008) 1.91
Effect of bone extracellular matrix synthesized in vitro on the osteoblastic differentiation of marrow stromal cells. Biomaterials (2005) 1.85
Tissue engineering strategies for bone regeneration. Adv Biochem Eng Biotechnol (2005) 1.80
Design of a flow perfusion bioreactor system for bone tissue-engineering applications. Tissue Eng (2003) 1.79
Injectable biodegradable hydrogel composites for rabbit marrow mesenchymal stem cell and growth factor delivery for cartilage tissue engineering. Biomaterials (2007) 1.78
Dual growth factor delivery from degradable oligo(poly(ethylene glycol) fumarate) hydrogel scaffolds for cartilage tissue engineering. J Control Release (2005) 1.68
Fabrication of porous ultra-short single-walled carbon nanotube nanocomposite scaffolds for bone tissue engineering. Biomaterials (2007) 1.67
Dose effect of dual delivery of vascular endothelial growth factor and bone morphogenetic protein-2 on bone regeneration in a rat critical-size defect model. Tissue Eng Part A (2009) 1.67
Delivery of TGF-beta1 and chondrocytes via injectable, biodegradable hydrogels for cartilage tissue engineering applications. Biomaterials (2005) 1.63
Flow perfusion culture induces the osteoblastic differentiation of marrow stroma cell-scaffold constructs in the absence of dexamethasone. J Biomed Mater Res A (2005) 1.61
Injectable biomaterials for regenerating complex craniofacial tissues. Adv Mater (2009) 1.60
Use of stereolithography to manufacture critical-sized 3D biodegradable scaffolds for bone ingrowth. J Biomed Mater Res B Appl Biomater (2003) 1.59
Osteochondral repair in the rabbit model utilizing bilayered, degradable oligo(poly(ethylene glycol) fumarate) hydrogel scaffolds. J Biomed Mater Res A (2005) 1.58
Strategies for controlled delivery of growth factors and cells for bone regeneration. Adv Drug Deliv Rev (2012) 1.57
Engineering complex tissues. Sci Transl Med (2012) 1.54
Photocrosslinking characteristics and mechanical properties of diethyl fumarate/poly(propylene fumarate) biomaterials. Biomaterials (2002) 1.52
In vitro release of transforming growth factor-beta 1 from gelatin microparticles encapsulated in biodegradable, injectable oligo(poly(ethylene glycol) fumarate) hydrogels. J Control Release (2003) 1.52
Nanobiomaterial applications in orthopedics. J Orthop Res (2007) 1.51
Evaluation of bone regeneration using the rat critical size calvarial defect. Nat Protoc (2012) 1.51
Effect of initial cell seeding density on early osteogenic signal expression of rat bone marrow stromal cells cultured on cross-linked poly(propylene fumarate) disks. Biomacromolecules (2009) 1.48
Bioactive poly(L-lactic acid) conduits seeded with Schwann cells for peripheral nerve regeneration. Biomaterials (2002) 1.47
Formation of three-dimensional cell/polymer constructs for bone tissue engineering in a spinner flask and a rotating wall vessel bioreactor. J Biomed Mater Res (2002) 1.46
Transforming growth factor-beta 1 release from oligo(poly(ethylene glycol) fumarate) hydrogels in conditions that model the cartilage wound healing environment. J Control Release (2004) 1.45
Thermally cross-linked oligo(poly(ethylene glycol) fumarate) hydrogels support osteogenic differentiation of encapsulated marrow stromal cells in vitro. Biomacromolecules (2004) 1.45
Biodegradable gelatin microparticles as delivery systems for the controlled release of bone morphogenetic protein-2. Acta Biomater (2008) 1.43
Osteogenic differentiation of mesenchymal stem cells on pregenerated extracellular matrix scaffolds in the absence of osteogenic cell culture supplements. Tissue Eng Part A (2010) 1.38
Harnessing and modulating inflammation in strategies for bone regeneration. Tissue Eng Part B Rev (2011) 1.37
In vivo biocompatibility of ultra-short single-walled carbon nanotube/biodegradable polymer nanocomposites for bone tissue engineering. Bone (2008) 1.35
Review: mineralization of synthetic polymer scaffolds for bone tissue engineering. Tissue Eng (2007) 1.35
Pre-culture period of mesenchymal stem cells in osteogenic media influences their in vivo bone forming potential. J Biomed Mater Res A (2007) 1.34
Effect of poly(ethylene glycol) molecular weight on tensile and swelling properties of oligo(poly(ethylene glycol) fumarate) hydrogels for cartilage tissue engineering. J Biomed Mater Res (2002) 1.34
In vitro osteogenic differentiation of marrow stromal cells encapsulated in biodegradable hydrogels. J Biomed Mater Res A (2004) 1.32
Soft and hard tissue response to photocrosslinked poly(propylene fumarate) scaffolds in a rabbit model. J Biomed Mater Res (2002) 1.31
Kinetics of poly(propylene fumarate) synthesis by step polymerization of diethyl fumarate and propylene glycol using zinc chloride as a catalyst. J Biomater Sci Polym Ed (2002) 1.30
Flow perfusion enhances the calcified matrix deposition of marrow stromal cells in biodegradable nonwoven fiber mesh scaffolds. Ann Biomed Eng (2005) 1.29
In vitro cytotoxicity of injectable and biodegradable poly(propylene fumarate)-based networks: unreacted macromers, cross-linked networks, and degradation products. Biomacromolecules (2003) 1.29
The influence of an in vitro generated bone-like extracellular matrix on osteoblastic gene expression of marrow stromal cells. Biomaterials (2008) 1.29
Modeling Ewing sarcoma tumors in vitro with 3D scaffolds. Proc Natl Acad Sci U S A (2013) 1.23
Injectable nanocomposites of single-walled carbon nanotubes and biodegradable polymers for bone tissue engineering. Biomacromolecules (2006) 1.23
Influence of the porosity of starch-based fiber mesh scaffolds on the proliferation and osteogenic differentiation of bone marrow stromal cells cultured in a flow perfusion bioreactor. Tissue Eng (2006) 1.23
Modulation of differentiation and mineralization of marrow stromal cells cultured on biomimetic hydrogels modified with Arg-Gly-Asp containing peptides. J Biomed Mater Res A (2004) 1.22
Modulation of marrow stromal osteoblast adhesion on biomimetic oligo[poly(ethylene glycol) fumarate] hydrogels modified with Arg-Gly-Asp peptides and a poly(ethyleneglycol) spacer. J Biomed Mater Res (2002) 1.22
Angiogenesis with biomaterial-based drug- and cell-delivery systems. J Biomater Sci Polym Ed (2004) 1.21
In vitro and in vivo release of vascular endothelial growth factor from gelatin microparticles and biodegradable composite scaffolds. Pharm Res (2008) 1.21
Repair of osteochondral defects with biodegradable hydrogel composites encapsulating marrow mesenchymal stem cells in a rabbit model. Acta Biomater (2009) 1.21
Synthesis of poly(propylene fumarate). Nat Protoc (2009) 1.20
Effect of flow perfusion on the osteogenic differentiation of bone marrow stromal cells cultured on starch-based three-dimensional scaffolds. J Biomed Mater Res A (2003) 1.20
In vivo bone and soft tissue response to injectable, biodegradable oligo(poly(ethylene glycol) fumarate) hydrogels. Biomaterials (2003) 1.19
Engineering tumors: a tissue engineering perspective in cancer biology. Tissue Eng Part B Rev (2010) 1.19
Effect of dual growth factor delivery on chondrogenic differentiation of rabbit marrow mesenchymal stem cells encapsulated in injectable hydrogel composites. J Biomed Mater Res A (2009) 1.18
Synthesis and characterization of injectable, thermally and chemically gelable, amphiphilic poly(N-isopropylacrylamide)-based macromers. Biomacromolecules (2008) 1.18
Effect of swelling ratio of injectable hydrogel composites on chondrogenic differentiation of encapsulated rabbit marrow mesenchymal stem cells in vitro. Biomacromolecules (2009) 1.18
Osteogenic differentiation of rat bone marrow stromal cells cultured on Arg-Gly-Asp modified hydrogels without dexamethasone and beta-glycerol phosphate. Biomaterials (2005) 1.17
Enhanced chondrogenesis in co-cultures with articular chondrocytes and mesenchymal stem cells. Biomaterials (2012) 1.17
Bioactive polymer/extracellular matrix scaffolds fabricated with a flow perfusion bioreactor for cartilage tissue engineering. Biomaterials (2010) 1.16
In vitro localization of bone growth factors in constructs of biodegradable scaffolds seeded with marrow stromal cells and cultured in a flow perfusion bioreactor. Tissue Eng (2006) 1.15
In vitro generation of an osteochondral construct using injectable hydrogel composites encapsulating rabbit marrow mesenchymal stem cells. Biomaterials (2009) 1.13
Attachment, proliferation, and migration of marrow stromal osteoblasts cultured on biomimetic hydrogels modified with an osteopontin-derived peptide. Biomaterials (2004) 1.13
Uncultured marrow mononuclear cells delivered within fibrin glue hydrogels to porous scaffolds enhance bone regeneration within critical-sized rat cranial defects. Tissue Eng Part A (2010) 1.12
Repair of osteochondral defects with hyaluronan- and polyester-based scaffolds. Osteoarthritis Cartilage (2005) 1.11
In vitro degradation of polymeric networks of poly(propylene fumarate) and the crosslinking macromer poly(propylene fumarate)-diacrylate. Biomaterials (2003) 1.11
Two-dimensional nanostructure-reinforced biodegradable polymeric nanocomposites for bone tissue engineering. Biomacromolecules (2013) 1.11
The effect of hypoxia on the chondrogenic differentiation of co-cultured articular chondrocytes and mesenchymal stem cells in scaffolds. Biomaterials (2013) 1.10
Gadofullerenes as nanoscale magnetic labels for cellular MRI. Contrast Media Mol Imaging (2007) 1.09
Synthesis of oligo(poly(ethylene glycol) fumarate). Nat Protoc (2012) 1.09
Flow perfusion culture of marrow stromal osteoblasts in titanium fiber mesh. J Biomed Mater Res A (2003) 1.09
Bone response and mechanical strength of rabbit femoral defects filled with injectable CaP cements containing TGF-beta 1 loaded gelatin microparticles. Biomaterials (2007) 1.08
Osteochondral tissue regeneration using a bilayered composite hydrogel with modulating dual growth factor release kinetics in a rabbit model. J Control Release (2013) 1.08