| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.
|
Nat Genet
|
2010
|
17.89
|
|
2
|
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk.
|
Nature
|
2011
|
13.25
|
|
3
|
Association of socioeconomic position with health behaviors and mortality.
|
JAMA
|
2010
|
7.64
|
|
4
|
Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge.
|
Nat Genet
|
2010
|
6.66
|
|
5
|
Timing of onset of cognitive decline: results from Whitehall II prospective cohort study.
|
BMJ
|
2012
|
5.26
|
|
6
|
The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis.
|
Lancet
|
2012
|
4.87
|
|
7
|
Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways.
|
Nat Genet
|
2012
|
4.73
|
|
8
|
A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.
|
Nat Genet
|
2012
|
4.37
|
|
9
|
Use of low-density lipoprotein cholesterol gene score to distinguish patients with polygenic and monogenic familial hypercholesterolaemia: a case-control study.
|
Lancet
|
2013
|
3.87
|
|
10
|
Work stress and coronary heart disease: what are the mechanisms?
|
Eur Heart J
|
2008
|
3.56
|
|
11
|
Bidirectional association between depression and metabolic syndrome: a systematic review and meta-analysis of epidemiological studies.
|
Diabetes Care
|
2012
|
3.53
|
|
12
|
Metabolically healthy obesity and risk of mortality: does the definition of metabolic health matter?
|
Diabetes Care
|
2013
|
3.43
|
|
13
|
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals.
|
PLoS Genet
|
2012
|
3.21
|
|
14
|
Common variants associated with plasma triglycerides and risk for coronary artery disease.
|
Nat Genet
|
2013
|
2.92
|
|
15
|
Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits.
|
PLoS Genet
|
2013
|
2.83
|
|
16
|
Data resource profile: cardiovascular disease research using linked bespoke studies and electronic health records (CALIBER).
|
Int J Epidemiol
|
2012
|
2.75
|
|
17
|
Association of diurnal patterns in salivary cortisol with all-cause and cardiovascular mortality: findings from the Whitehall II study.
|
J Clin Endocrinol Metab
|
2011
|
2.68
|
|
18
|
Hypertension awareness and psychological distress.
|
Hypertension
|
2010
|
2.61
|
|
19
|
Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci.
|
Am J Hum Genet
|
2012
|
2.53
|
|
20
|
Dietary pattern and depressive symptoms in middle age.
|
Br J Psychiatry
|
2009
|
2.28
|
|
21
|
Effect of intensity and type of physical activity on mortality: results from the Whitehall II cohort study.
|
Am J Public Health
|
2011
|
2.19
|
|
22
|
Alcohol consumption and cognitive decline in early old age.
|
Neurology
|
2014
|
2.18
|
|
23
|
Secretory phospholipase A(2)-IIA and cardiovascular disease: a mendelian randomization study.
|
J Am Coll Cardiol
|
2013
|
2.18
|
|
24
|
Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height.
|
Am J Hum Genet
|
2010
|
2.15
|
|
25
|
Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
|
Am J Hum Genet
|
2009
|
2.04
|
|
26
|
Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.
|
Am J Hum Genet
|
2012
|
1.96
|
|
27
|
Height, wealth, and health: an overview with new data from three longitudinal studies.
|
Econ Hum Biol
|
2009
|
1.95
|
|
28
|
Low HDL cholesterol is a risk factor for deficit and decline in memory in midlife: the Whitehall II study.
|
Arterioscler Thromb Vasc Biol
|
2008
|
1.88
|
|
29
|
Gender differences in the cross-sectional relationships between sleep duration and markers of inflammation: Whitehall II study.
|
Sleep
|
2009
|
1.77
|
|
30
|
Comparative analysis of genome-wide association studies signals for lipids, diabetes, and coronary heart disease: Cardiovascular Biomarker Genetics Collaboration.
|
Eur Heart J
|
2011
|
1.73
|
|
31
|
Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders.
|
Nat Genet
|
2013
|
1.72
|
|
32
|
Persistent cognitive depressive symptoms are associated with coronary artery calcification.
|
Atherosclerosis
|
2010
|
1.72
|
|
33
|
A genome-wide association search for type 2 diabetes genes in African Americans.
|
PLoS One
|
2012
|
1.72
|
|
34
|
Life course trajectories of systolic blood pressure using longitudinal data from eight UK cohorts.
|
PLoS Med
|
2011
|
1.71
|
|
35
|
Measures of frailty in population-based studies: an overview.
|
BMC Geriatr
|
2013
|
1.69
|
|
36
|
Body mass index over the adult life course and cognition in late midlife: the Whitehall II Cohort Study.
|
Am J Clin Nutr
|
2008
|
1.65
|
|
37
|
Objectively measured secondhand smoke exposure and risk of cardiovascular disease: what is the mediating role of inflammatory and hemostatic factors?
|
J Am Coll Cardiol
|
2010
|
1.60
|
|
38
|
Sleep disturbances and cause-specific mortality: Results from the GAZEL cohort study.
|
Am J Epidemiol
|
2010
|
1.57
|
|
39
|
Alternative Healthy Eating Index and mortality over 18 y of follow-up: results from the Whitehall II cohort.
|
Am J Clin Nutr
|
2011
|
1.54
|
|
40
|
A genome-wide association study of aging.
|
Neurobiol Aging
|
2011
|
1.54
|
|
41
|
A prospective study of positive psychological well-being and coronary heart disease.
|
Health Psychol
|
2011
|
1.49
|
|
42
|
A nonlinear relationship of generalized and central obesity with diurnal cortisol secretion in the Whitehall II study.
|
J Clin Endocrinol Metab
|
2010
|
1.46
|
|
43
|
Association between questionnaire- and accelerometer-assessed physical activity: the role of sociodemographic factors.
|
Am J Epidemiol
|
2014
|
1.45
|
|
44
|
Blood pressure loci identified with a gene-centric array.
|
Am J Hum Genet
|
2011
|
1.44
|
|
45
|
Positive and negative affect and risk of coronary heart disease: Whitehall II prospective cohort study.
|
BMJ
|
2008
|
1.42
|
|
46
|
The natural course of healthy obesity over 20 years.
|
J Am Coll Cardiol
|
2015
|
1.31
|
|
47
|
Heart health when life is satisfying: evidence from the Whitehall II cohort study.
|
Eur Heart J
|
2011
|
1.30
|
|
48
|
Influence of common genetic variation on blood lipid levels, cardiovascular risk, and coronary events in two British prospective cohort studies.
|
Eur Heart J
|
2012
|
1.30
|
|
49
|
Health behaviors from early to late midlife as predictors of cognitive function: The Whitehall II study.
|
Am J Epidemiol
|
2009
|
1.30
|
|
50
|
Genetic variation in complement factor H and risk of coronary heart disease: eight new studies and a meta-analysis of around 48,000 individuals.
|
Atherosclerosis
|
2010
|
1.27
|
|
51
|
Physical activity and inflammatory markers over 10 years: follow-up in men and women from the Whitehall II cohort study.
|
Circulation
|
2012
|
1.25
|
|
52
|
Social inequality in walking speed in early old age in the Whitehall II study.
|
J Gerontol A Biol Sci Med Sci
|
2009
|
1.24
|
|
53
|
Antidepressant medication use and future risk of cardiovascular disease: the Scottish Health Survey.
|
Eur Heart J
|
2010
|
1.24
|
|
54
|
Influence of individual and combined healthy behaviours on successful aging.
|
CMAJ
|
2012
|
1.24
|
|
55
|
Socioeconomic status, structural and functional measures of social support, and mortality: The British Whitehall II Cohort Study, 1985-2009.
|
Am J Epidemiol
|
2012
|
1.21
|
|
56
|
Longitudinal patterns in physical activity and sedentary behaviour from mid-life to early old age: a substudy of the Whitehall II cohort.
|
J Epidemiol Community Health
|
2012
|
1.20
|
|
57
|
Separating the mechanism-based and off-target actions of cholesteryl ester transfer protein inhibitors with CETP gene polymorphisms.
|
Circulation
|
2009
|
1.20
|
|
58
|
Rising adiposity curbing decline in the incidence of myocardial infarction: 20-year follow-up of British men and women in the Whitehall II cohort.
|
Eur Heart J
|
2011
|
1.18
|
|
59
|
The role of conventional risk factors in explaining social inequalities in coronary heart disease: the relative and absolute approaches to risk.
|
Epidemiology
|
2008
|
1.16
|
|
60
|
PLA2G7 genotype, lipoprotein-associated phospholipase A2 activity, and coronary heart disease risk in 10 494 cases and 15 624 controls of European Ancestry.
|
Circulation
|
2010
|
1.14
|
|
61
|
Cortisol secretion and fatigue: associations in a community based cohort.
|
Psychoneuroendocrinology
|
2009
|
1.14
|
|
62
|
Arterial stiffness, physical function, and functional limitation: the Whitehall II Study.
|
Hypertension
|
2011
|
1.13
|
|
63
|
Walking speed and subclinical atherosclerosis in healthy older adults: the Whitehall II study.
|
Heart
|
2009
|
1.13
|
|
64
|
Employee control over working times and risk of cause-specific disability pension: the Finnish Public Sector Study.
|
Occup Environ Med
|
2009
|
1.10
|
|
65
|
Why does lung function predict mortality? Results from the Whitehall II Cohort Study.
|
Am J Epidemiol
|
2010
|
1.10
|
|
66
|
Socioeconomic status moderates the association between carotid intima-media thickness and cognition in midlife: evidence from the Whitehall II study.
|
Atherosclerosis
|
2007
|
1.08
|
|
67
|
Overall diet history and reversibility of the metabolic syndrome over 5 years: the Whitehall II prospective cohort study.
|
Diabetes Care
|
2010
|
1.08
|
|
68
|
Impact of smoking on cognitive decline in early old age: the Whitehall II cohort study.
|
Arch Gen Psychiatry
|
2012
|
1.08
|
|
69
|
Psychological distress as a risk factor for death from cerebrovascular disease.
|
CMAJ
|
2012
|
1.06
|
|
70
|
Do psychological factors affect inflammation and incident coronary heart disease: the Whitehall II Study.
|
Arterioscler Thromb Vasc Biol
|
2008
|
1.06
|
|
71
|
Association of walking speed in late midlife with mortality: results from the Whitehall II cohort study.
|
Age (Dordr)
|
2012
|
1.04
|
|
72
|
Genetics of cortisol secretion and depressive symptoms: a candidate gene and genome wide association approach.
|
Psychoneuroendocrinology
|
2011
|
1.03
|
|
73
|
Apolipoprotein E genotype, cardiovascular biomarkers and risk of stroke: systematic review and meta-analysis of 14,015 stroke cases and pooled analysis of primary biomarker data from up to 60,883 individuals.
|
Int J Epidemiol
|
2013
|
1.03
|
|
74
|
Population genomics of cardiometabolic traits: design of the University College London-London School of Hygiene and Tropical Medicine-Edinburgh-Bristol (UCLEB) Consortium.
|
PLoS One
|
2013
|
1.02
|
|
75
|
Evaluating the causal relevance of diverse risk markers: horizontal systematic review.
|
BMJ
|
2009
|
1.02
|
|
76
|
Does sickness absence due to psychiatric disorder predict cause-specific mortality? A 16-year follow-up of the GAZEL occupational cohort study.
|
Am J Epidemiol
|
2010
|
1.01
|
|
77
|
Fasting glucose, diagnosis of type 2 diabetes, and depression: the Vietnam experience study.
|
Biol Psychiatry
|
2010
|
1.00
|
|
78
|
The relationship between plasma angiopoietin-like protein 4 levels, angiopoietin-like protein 4 genotype, and coronary heart disease risk.
|
Arterioscler Thromb Vasc Biol
|
2010
|
1.00
|
|
79
|
Four genetic loci influencing electrocardiographic indices of left ventricular hypertrophy.
|
Circ Cardiovasc Genet
|
2011
|
0.99
|
|
80
|
Risk factors for pancreatic cancer mortality: extended follow-up of the original Whitehall Study.
|
Cancer Epidemiol Biomarkers Prev
|
2009
|
0.98
|
|
81
|
Association of lung function with physical, mental and cognitive function in early old age.
|
Age (Dordr)
|
2010
|
0.97
|
|
82
|
Genetic variants associated with Von Willebrand factor levels in healthy men and women identified using the HumanCVD BeadChip.
|
Ann Hum Genet
|
2011
|
0.96
|
|
83
|
Effect of retirement on alcohol consumption: longitudinal evidence from the French Gazel cohort study.
|
PLoS One
|
2011
|
0.96
|
|
84
|
Cardiovascular disease risk factors in relation to suicide mortality in Asia: prospective cohort study of over one million Korean men and women.
|
Eur Heart J
|
2011
|
0.94
|
|
85
|
Walking pace, leisure time physical activity, and resting heart rate in relation to disease-specific mortality in London: 40 years follow-up of the original Whitehall study. An update of our work with professor Jerry N. Morris (1910-2009).
|
Ann Epidemiol
|
2010
|
0.94
|
|
86
|
Depressive disorder, coronary heart disease, and stroke: dose-response and reverse causation effects in the Whitehall II cohort study.
|
Eur J Prev Cardiol
|
2014
|
0.94
|
|
87
|
Low conscientiousness and risk of all-cause, cardiovascular and cancer mortality over 17 years: Whitehall II cohort study.
|
J Psychosom Res
|
2012
|
0.93
|
|
88
|
Using sickness absence records to predict future depression in a working population: prospective findings from the GAZEL cohort.
|
Am J Public Health
|
2009
|
0.93
|
|
89
|
Combined impact of smoking and heavy alcohol use on cognitive decline in early old age: Whitehall II prospective cohort study.
|
Br J Psychiatry
|
2013
|
0.93
|
|
90
|
Trends in the association between height and socioeconomic indicators in France, 1970-2003.
|
Econ Hum Biol
|
2010
|
0.92
|
|
91
|
Predictors of sustained organizational commitment among nurses with temporary job contracts.
|
J Nurs Adm
|
2006
|
0.92
|
|
92
|
The combined influence of hypertension and common mental disorder on all-cause and cardiovascular disease mortality.
|
J Hypertens
|
2010
|
0.92
|
|
93
|
Obesity and overweight in relation to mortality in men with and without type 2 diabetes/impaired glucose tolerance: the original Whitehall Study.
|
Diabetes Care
|
2007
|
0.92
|
|
94
|
Do socioeconomic factors shape weight and obesity trajectories over the transition from midlife to old age? Results from the French GAZEL cohort study.
|
Am J Clin Nutr
|
2010
|
0.92
|
|
95
|
Work characteristics and personal social support as determinants of subjective well-being.
|
PLoS One
|
2013
|
0.92
|
|
96
|
Effect of Apolipoprotein E epsilon4 on the association between health behaviors and cognitive function in late midlife.
|
Mol Neurodegener
|
2010
|
0.90
|
|
97
|
Metabolic syndrome and onset of depressive symptoms in the elderly: findings from the three-city study.
|
Diabetes Care
|
2011
|
0.90
|
|
98
|
Metabolic syndrome over 10 years and cognitive functioning in late midlife: the Whitehall II study.
|
Diabetes Care
|
2009
|
0.90
|
|
99
|
Consent to DNA collection in epidemiological studies: findings from the Whitehall II cohort and the English Longitudinal Study of Ageing.
|
Genet Med
|
2012
|
0.89
|
|
100
|
A non-exercise testing method for estimating cardiorespiratory fitness: associations with all-cause and cardiovascular mortality in a pooled analysis of eight population-based cohorts.
|
Eur Heart J
|
2012
|
0.89
|
|
101
|
Do psychological attributes matter for adherence to antihypertensive medication? The Finnish Public Sector Cohort Study.
|
J Hypertens
|
2008
|
0.89
|
|
102
|
Does overall diet in midlife predict future aging phenotypes? A cohort study.
|
Am J Med
|
2013
|
0.88
|
|
103
|
Metabolic syndrome, its components, and mortality in the elderly.
|
J Clin Endocrinol Metab
|
2010
|
0.88
|
|
104
|
Dysregulation of the hypothalamic pituitary adrenal (HPA) axis and physical performance at older ages: an individual participant meta-analysis.
|
Psychoneuroendocrinology
|
2012
|
0.88
|
|
105
|
Risk factors for colonic and rectal cancer mortality: evidence from 40 years' follow-up in the Whitehall I study.
|
J Epidemiol Community Health
|
2011
|
0.88
|
|
106
|
Adherence to healthy dietary guidelines and future depressive symptoms: evidence for sex differentials in the Whitehall II study.
|
Am J Clin Nutr
|
2013
|
0.88
|
|
107
|
Gene-centric analysis identifies variants associated with interleukin-6 levels and shared pathways with other inflammation markers.
|
Circ Cardiovasc Genet
|
2013
|
0.86
|
|
108
|
No interactions between previously associated 2-hour glucose gene variants and physical activity or BMI on 2-hour glucose levels.
|
Diabetes
|
2012
|
0.86
|
|
109
|
Subjective cognitive complaints and mortality: does the type of complaint matter?
|
J Psychiatr Res
|
2013
|
0.85
|
|
110
|
Association of hostility with sleep duration and sleep disturbances in an employee population.
|
Int J Behav Med
|
2008
|
0.85
|
|
111
|
Comparison of risk factors for fatal stroke and ischemic heart disease: a prospective follow up of the health survey for England.
|
Atherosclerosis
|
2011
|
0.85
|
|
112
|
Combined effect of physical activity and leisure time sitting on long-term risk of incident obesity and metabolic risk factor clustering.
|
Diabetologia
|
2014
|
0.84
|
|
113
|
Association of maternal and paternal IQ with offspring conduct, emotional, and attention problem scores. Transgenerational evidence from the 1958 British Birth Cohort Study.
|
Arch Gen Psychiatry
|
2011
|
0.84
|
|
114
|
Diabetes and raised blood glucose as risk factors for future suicide: cohort study of 1 234 927 Korean men and women.
|
J Epidemiol Community Health
|
2012
|
0.83
|
|
115
|
Do different measures of early life socioeconomic circumstances predict adult mortality? Evidence from the British Whitehall II and French GAZEL studies.
|
J Epidemiol Community Health
|
2010
|
0.83
|
|
116
|
Meta analysis of candidate gene variants outside the LPA locus with Lp(a) plasma levels in 14,500 participants of six White European cohorts.
|
Atherosclerosis
|
2011
|
0.83
|
|
117
|
Taking the tension out of hypertension: a prospective study of psychological well being and hypertension.
|
J Hypertens
|
2014
|
0.83
|
|
118
|
Socioeconomic and ethnic differences in use of lipid-lowering drugs after deregulation of simvastatin in the UK: the Whitehall II prospective cohort study.
|
Atherosclerosis
|
2010
|
0.83
|
|
119
|
Height loss and future coronary heart disease in London: the Whitehall II study.
|
J Epidemiol Community Health
|
2010
|
0.82
|
|
120
|
Metabolic syndrome and disability: findings from the prospective three-city study.
|
J Gerontol A Biol Sci Med Sci
|
2013
|
0.82
|
|
121
|
Absence of association of a single-nucleotide polymorphism in the TERT-CLPTM1L locus with age-related phenotypes in a large multicohort study: the HALCyon programme.
|
Aging Cell
|
2011
|
0.82
|
|
122
|
Cognition and incident coronary heart disease in late midlife: The Whitehall II study.
|
Intelligence
|
2009
|
0.82
|
|
123
|
Causal relevance of blood lipid fractions in the development of carotid atherosclerosis: Mendelian randomization analysis.
|
Circ Cardiovasc Genet
|
2012
|
0.82
|
|
124
|
Effect of Smoking on Blood Pressure and Resting Heart Rate: A Mendelian Randomization Meta-Analysis in the CARTA Consortium.
|
Circ Cardiovasc Genet
|
2015
|
0.82
|
|
125
|
A gene-centric association scan for Coagulation Factor VII levels in European and African Americans: the Candidate Gene Association Resource (CARe) Consortium.
|
Hum Mol Genet
|
2011
|
0.81
|
|
126
|
Gene-targeted analysis of copy number variants identifies 3 novel associations with coronary heart disease traits.
|
Circ Cardiovasc Genet
|
2012
|
0.79
|
|
127
|
Hostility and trajectories of body mass index over 19 years: the Whitehall II Study.
|
Am J Epidemiol
|
2008
|
0.79
|
|
128
|
Associations between a polymorphism in the pleiotropic GCKR and Age-related phenotypes: the HALCyon programme.
|
PLoS One
|
2013
|
0.79
|
|
129
|
Integration of genetics into a systems model of electrocardiographic traits using HumanCVD BeadChip.
|
Circ Cardiovasc Genet
|
2012
|
0.79
|
|
130
|
Impact of smoking cessation advice on future smoking behavior, morbidity, and mortality: up to 40 years of follow-up of the first randomized controlled trial of a general population sample.
|
Arch Intern Med
|
2011
|
0.79
|
|
131
|
Associations between APOE and low-density lipoprotein cholesterol genotypes and cognitive and physical capability: the HALCyon programme.
|
Age (Dordr)
|
2014
|
0.78
|
|
132
|
Does working while ill trigger serious coronary events? The Whitehall II study.
|
J Occup Environ Med
|
2009
|
0.78
|
|
133
|
Effort-reward imbalance, heart rate, and heart rate variability: the Cardiovascular Risk in Young Finns Study.
|
Int J Behav Med
|
2007
|
0.78
|
|
134
|
Novel genetic approach to investigate the role of plasma secretory phospholipase A2 (sPLA2)-V isoenzyme in coronary heart disease: modified Mendelian randomization analysis using PLA2G5 expression levels.
|
Circ Cardiovasc Genet
|
2014
|
0.78
|
|
135
|
A genetic instrument for Mendelian randomization of fibrinogen.
|
Eur J Epidemiol
|
2012
|
0.78
|
|
136
|
Alcohol consumption and cognitive performance: a Mendelian randomization study.
|
Addiction
|
2014
|
0.78
|
|
137
|
The healthy population-high disability paradox.
|
Occup Environ Med
|
2014
|
0.77
|
|
138
|
The effect of renin angiotensin system genetic variants in acute pancreatitis.
|
Ann Surg
|
2015
|
0.77
|
|
139
|
Association of body mass index and waist circumference with successful aging.
|
Obesity (Silver Spring)
|
2013
|
0.77
|
|
140
|
Socioeconomic inequalities in health in 22 European countries.
|
N Engl J Med
|
2008
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