| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Biological, clinical and population relevance of 95 loci for blood lipids.
|
Nature
|
2010
|
28.21
|
|
2
|
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index.
|
Nat Genet
|
2010
|
23.08
|
|
3
|
Hundreds of variants clustered in genomic loci and biological pathways affect human height.
|
Nature
|
2010
|
20.01
|
|
4
|
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.
|
Nat Genet
|
2010
|
17.89
|
|
5
|
Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.
|
Nat Genet
|
2008
|
12.32
|
|
6
|
Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study.
|
Lancet
|
2012
|
12.10
|
|
7
|
Genome-wide association analysis of metabolic traits in a birth cohort from a founder population.
|
Nat Genet
|
2008
|
12.07
|
|
8
|
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes.
|
Nat Genet
|
2012
|
11.09
|
|
9
|
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution.
|
Nat Genet
|
2010
|
7.94
|
|
10
|
Large-scale association analysis identifies new risk loci for coronary artery disease.
|
Nat Genet
|
2012
|
7.59
|
|
11
|
Sequence variants at CHRNB3-CHRNA6 and CYP2A6 affect smoking behavior.
|
Nat Genet
|
2010
|
6.49
|
|
12
|
Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways.
|
Nat Genet
|
2012
|
4.73
|
|
13
|
Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.
|
PLoS Genet
|
2009
|
4.71
|
|
14
|
GWAS of 126,559 individuals identifies genetic variants associated with educational attainment.
|
Science
|
2013
|
4.71
|
|
15
|
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.
|
Nat Genet
|
2014
|
4.13
|
|
16
|
Genome-wide association study identifies five loci associated with lung function.
|
Nat Genet
|
2009
|
4.10
|
|
17
|
Genetic variants influencing circulating lipid levels and risk of coronary artery disease.
|
Arterioscler Thromb Vasc Biol
|
2010
|
4.08
|
|
18
|
Genome-wide association study identifies multiple loci influencing human serum metabolite levels.
|
Nat Genet
|
2012
|
4.08
|
|
19
|
Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways.
|
Diabetes
|
2010
|
4.07
|
|
20
|
Identification of seven loci affecting mean telomere length and their association with disease.
|
Nat Genet
|
2013
|
3.87
|
|
21
|
Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels.
|
Circulation
|
2011
|
3.68
|
|
22
|
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.
|
Nat Genet
|
2013
|
3.25
|
|
23
|
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals.
|
PLoS Genet
|
2012
|
3.21
|
|
24
|
Genome-wide association analyses identify 18 new loci associated with serum urate concentrations.
|
Nat Genet
|
2012
|
3.04
|
|
25
|
Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.
|
Nat Genet
|
2011
|
3.03
|
|
26
|
Geographical structure and differential natural selection among North European populations.
|
Genome Res
|
2009
|
3.03
|
|
27
|
Common variants associated with plasma triglycerides and risk for coronary artery disease.
|
Nat Genet
|
2013
|
2.92
|
|
28
|
Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits.
|
PLoS Genet
|
2013
|
2.83
|
|
29
|
The genome-wide patterns of variation expose significant substructure in a founder population.
|
Am J Hum Genet
|
2008
|
2.79
|
|
30
|
FTO genotype is associated with phenotypic variability of body mass index.
|
Nature
|
2012
|
2.77
|
|
31
|
Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile.
|
Nat Genet
|
2011
|
2.73
|
|
32
|
Genetically determined height and coronary artery disease.
|
N Engl J Med
|
2015
|
2.24
|
|
33
|
Association of serum cotinine level with a cluster of three nicotinic acetylcholine receptor genes (CHRNA3/CHRNA5/CHRNB4) on chromosome 15.
|
Hum Mol Genet
|
2009
|
2.22
|
|
34
|
Metabonomic, transcriptomic, and genomic variation of a population cohort.
|
Mol Syst Biol
|
2010
|
2.17
|
|
35
|
Effect of five genetic variants associated with lung function on the risk of chronic obstructive lung disease, and their joint effects on lung function.
|
Am J Respir Crit Care Med
|
2011
|
2.07
|
|
36
|
Childhood adversities are associated with shorter telomere length at adult age both in individuals with an anxiety disorder and controls.
|
PLoS One
|
2010
|
2.03
|
|
37
|
Novel Loci for metabolic networks and multi-tissue expression studies reveal genes for atherosclerosis.
|
PLoS Genet
|
2012
|
1.97
|
|
38
|
Metabolic signatures of insulin resistance in 7,098 young adults.
|
Diabetes
|
2012
|
1.80
|
|
39
|
An immune response network associated with blood lipid levels.
|
PLoS Genet
|
2010
|
1.74
|
|
40
|
A genome-wide association search for type 2 diabetes genes in African Americans.
|
PLoS One
|
2012
|
1.72
|
|
41
|
The role of adiposity in cardiometabolic traits: a Mendelian randomization analysis.
|
PLoS Med
|
2013
|
1.70
|
|
42
|
Genome-wide screen for metabolic syndrome susceptibility Loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits.
|
Circ Cardiovasc Genet
|
2012
|
1.60
|
|
43
|
Impact of common variation in bone-related genes on type 2 diabetes and related traits.
|
Diabetes
|
2012
|
1.42
|
|
44
|
Coding haplotype analysis supports HCR as the putative susceptibility gene for psoriasis at the MHC PSORS1 locus.
|
Hum Mol Genet
|
2002
|
1.42
|
|
45
|
Distinct variants at LIN28B influence growth in height from birth to adulthood.
|
Am J Hum Genet
|
2010
|
1.37
|
|
46
|
Founder population-specific HapMap panel increases power in GWA studies through improved imputation accuracy and CNV tagging.
|
Genome Res
|
2010
|
1.32
|
|
47
|
Gender differences in genetic risk profiles for cardiovascular disease.
|
PLoS One
|
2008
|
1.31
|
|
48
|
A P3G generic access agreement for population genomic studies.
|
Nat Biotechnol
|
2013
|
1.28
|
|
49
|
Effect of catechol-o-methyltransferase-gene (COMT) variants on experimental and acute postoperative pain in 1,000 women undergoing surgery for breast cancer.
|
Anesthesiology
|
2013
|
1.27
|
|
50
|
Pain in 1,000 women treated for breast cancer: a prospective study of pain sensitivity and postoperative pain.
|
Anesthesiology
|
2013
|
1.24
|
|
51
|
Use of genome-wide expression data to mine the "Gray Zone" of GWA studies leads to novel candidate obesity genes.
|
PLoS Genet
|
2010
|
1.24
|
|
52
|
Analysis of detailed phenotype profiles reveals CHRNA5-CHRNA3-CHRNB4 gene cluster association with several nicotine dependence traits.
|
Nicotine Tob Res
|
2012
|
1.22
|
|
53
|
Determinants of the progression in lumbar degeneration: a 5-year follow-up study of adult male monozygotic twins.
|
Spine (Phila Pa 1976)
|
2006
|
1.20
|
|
54
|
Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity.
|
Hum Mol Genet
|
2013
|
1.19
|
|
55
|
Association of variants in DISC1 with psychosis-related traits in a large population cohort.
|
Arch Gen Psychiatry
|
2009
|
1.19
|
|
56
|
SAIL--a software system for sample and phenotype availability across biobanks and cohorts.
|
Bioinformatics
|
2010
|
1.15
|
|
57
|
Genomic association analysis of common variants influencing antihypertensive response to hydrochlorothiazide.
|
Hypertension
|
2013
|
1.14
|
|
58
|
Genetic risk prediction and a 2-stage risk screening strategy for coronary heart disease.
|
Arterioscler Thromb Vasc Biol
|
2013
|
1.13
|
|
59
|
Detailed metabolic and genetic characterization reveals new associations for 30 known lipid loci.
|
Hum Mol Genet
|
2011
|
1.13
|
|
60
|
Increased genetic vulnerability to smoking at CHRNA5 in early-onset smokers.
|
Arch Gen Psychiatry
|
2012
|
1.08
|
|
61
|
NordicDB: a Nordic pool and portal for genome-wide control data.
|
Eur J Hum Genet
|
2010
|
1.07
|
|
62
|
The genetic structure of the Swedish population.
|
PLoS One
|
2011
|
1.05
|
|
63
|
Pubertal timing and growth influences cardiometabolic risk factors in adult males and females.
|
Diabetes Care
|
2012
|
1.04
|
|
64
|
From genetic discovery to future personalized health research.
|
N Biotechnol
|
2012
|
0.98
|
|
65
|
A genome-wide screen for interactions reveals a new locus on 4p15 modifying the effect of waist-to-hip ratio on total cholesterol.
|
PLoS Genet
|
2011
|
0.97
|
|
66
|
Work-related exhaustion and telomere length: a population-based study.
|
PLoS One
|
2012
|
0.97
|
|
67
|
Adipose tissue gene expression analysis reveals changes in inflammatory, mitochondrial respiratory and lipid metabolic pathways in obese insulin-resistant subjects.
|
BMC Med Genomics
|
2012
|
0.96
|
|
68
|
The molecular genetic architecture of self-employment.
|
PLoS One
|
2013
|
0.96
|
|
69
|
A genome-wide association study of monozygotic twin-pairs suggests a locus related to variability of serum high-density lipoprotein cholesterol.
|
Twin Res Hum Genet
|
2012
|
0.95
|
|
70
|
A random change point model for assessing variability in repeated measures of cognitive function.
|
Stat Med
|
2008
|
0.95
|
|
71
|
Association of known loci with lipid levels among children and prediction of dyslipidemia in adults.
|
Circ Cardiovasc Genet
|
2011
|
0.93
|
|
72
|
Genomic, transcriptomic, and lipidomic profiling highlights the role of inflammation in individuals with low high-density lipoprotein cholesterol.
|
Arterioscler Thromb Vasc Biol
|
2013
|
0.93
|
|
73
|
Genetic variants and blood pressure in a population-based cohort: the Cardiovascular Risk in Young Finns study.
|
Hypertension
|
2011
|
0.91
|
|
74
|
European lactase persistence genotype shows evidence of association with increase in body mass index.
|
Hum Mol Genet
|
2009
|
0.91
|
|
75
|
Genetic profiling using genome-wide significant coronary artery disease risk variants does not improve the prediction of subclinical atherosclerosis: the Cardiovascular Risk in Young Finns Study, the Bogalusa Heart Study and the Health 2000 Survey--a meta-analysis of three independent studies.
|
PLoS One
|
2012
|
0.90
|
|
76
|
Partial sleep restriction activates immune response-related gene expression pathways: experimental and epidemiological studies in humans.
|
PLoS One
|
2013
|
0.89
|
|
77
|
Missing value imputation in longitudinal measures of alcohol consumption.
|
Int J Methods Psychiatr Res
|
2011
|
0.88
|
|
78
|
Genome-wide meta-analysis of common variant differences between men and women.
|
Hum Mol Genet
|
2012
|
0.88
|
|
79
|
Genetic architecture of circulating lipid levels.
|
Eur J Hum Genet
|
2011
|
0.88
|
|
80
|
Phenotype mining in CNV carriers from a population cohort.
|
Hum Mol Genet
|
2011
|
0.87
|
|
81
|
Genetic association and interaction analysis of USF1 and APOA5 on lipid levels and atherosclerosis.
|
Arterioscler Thromb Vasc Biol
|
2009
|
0.87
|
|
82
|
Psychiatric comorbidity in couples: a longitudinal study of 202,959 married and cohabiting individuals.
|
Soc Psychiatry Psychiatr Epidemiol
|
2010
|
0.87
|
|
83
|
A longitudinal Swedish study on screening for squamous cell carcinoma and adenocarcinoma: evidence of effectiveness and overtreatment.
|
Cancer Epidemiol Biomarkers Prev
|
2007
|
0.86
|
|
84
|
Associations of nicotine intake measures with CHRN genes in Finnish smokers.
|
Nicotine Tob Res
|
2011
|
0.86
|
|
85
|
A genome-wide analysis of populations from European Russia reveals a new pole of genetic diversity in northern Europe.
|
PLoS One
|
2013
|
0.83
|
|
86
|
Towards a molecular systems model of coronary artery disease.
|
Curr Cardiol Rep
|
2014
|
0.82
|
|
87
|
Support for involvement of glutamate decarboxylase 1 and neuropeptide Y in anxiety susceptibility.
|
Am J Med Genet B Neuropsychiatr Genet
|
2012
|
0.81
|
|
88
|
Further evidence for the role of ENPP1 in obesity: association with morbid obesity in Finns.
|
Obesity (Silver Spring)
|
2008
|
0.80
|
|
89
|
Pharmacogenomics of hypertension: a genome‐wide, placebo‐controlled cross‐over study, using four classes of antihypertensive drugs.
|
J Am Heart Assoc
|
2015
|
0.79
|
|
90
|
A common variant near the KCNJ2 gene is associated with T-peak to T-end interval.
|
Heart Rhythm
|
2012
|
0.78
|
|
91
|
Diagnostic efficacy of myeloperoxidase to identify acute coronary syndrome in subjects with chest pain.
|
Ann Med
|
2013
|
0.77
|
|
92
|
The influence of mortality on twin models of change: addressing missingness through multiple imputation.
|
Behav Genet
|
2003
|
0.77
|
|
93
|
Does expecting more pain make it more intense? Factors associated with the first week pain trajectories after breast cancer surgery.
|
Pain
|
2017
|
0.75
|
|
94
|
Hierarchical Bayesian model for rare variant association analysis integrating genotype uncertainty in human sequence data.
|
Genet Epidemiol
|
2014
|
0.75
|
|
95
|
[Genetics of multifactorial diseases].
|
Duodecim
|
2010
|
0.75
|
|
96
|
Correction: Effect of Insulin Resistance on Monounsaturated Fatty Acid Levels: A Multi-cohort Non-targeted Metabolomics and Mendelian Randomization Study.
|
PLoS Genet
|
2017
|
0.75
|
|
97
|
Bayesian latent variable collapsing model for detecting rare variant interaction effect in twin study.
|
Genet Epidemiol
|
2014
|
0.75
|
|
98
|
Determinants of changes in bone density: a 5-year follow-up study of adult male monozygotic twins.
|
J Clin Densitom
|
2007
|
0.75
|