Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
1
|
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index.
|
Nat Genet
|
2010
|
23.08
|
2
|
Hundreds of variants clustered in genomic loci and biological pathways affect human height.
|
Nature
|
2010
|
20.01
|
3
|
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.
|
Nat Genet
|
2010
|
17.89
|
4
|
Replicating genotype-phenotype associations.
|
Nature
|
2007
|
16.11
|
5
|
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk.
|
Nature
|
2011
|
13.25
|
6
|
Population stratification and spurious allelic association.
|
Lancet
|
2003
|
10.53
|
7
|
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution.
|
Nat Genet
|
2010
|
7.94
|
8
|
Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction.
|
Nat Genet
|
2009
|
6.83
|
9
|
C-reactive protein and its role in metabolic syndrome: mendelian randomisation study.
|
Lancet
|
2005
|
5.51
|
10
|
GWAS of 126,559 individuals identifies genetic variants associated with educational attainment.
|
Science
|
2013
|
4.71
|
11
|
A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance.
|
Nat Genet
|
2012
|
4.37
|
12
|
Common genetic variants of the FADS1 FADS2 gene cluster and their reconstructed haplotypes are associated with the fatty acid composition in phospholipids.
|
Hum Mol Genet
|
2006
|
4.13
|
13
|
Genome-wide association study identifies five loci associated with lung function.
|
Nat Genet
|
2009
|
4.10
|
14
|
Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure.
|
Nat Genet
|
2011
|
3.40
|
15
|
Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies.
|
Nat Genet
|
2010
|
3.37
|
16
|
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture.
|
Nat Genet
|
2013
|
3.25
|
17
|
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals.
|
PLoS Genet
|
2012
|
3.21
|
18
|
Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.
|
Nat Genet
|
2011
|
3.03
|
19
|
Genetic epidemiology and public health: hope, hype, and future prospects.
|
Lancet
|
2005
|
3.00
|
20
|
Role of prostanoid DP receptor variants in susceptibility to asthma.
|
N Engl J Med
|
2004
|
2.86
|
21
|
Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits.
|
PLoS Genet
|
2013
|
2.83
|
22
|
FTO genotype is associated with phenotypic variability of body mass index.
|
Nature
|
2012
|
2.77
|
23
|
A genome-wide association meta-analysis identifies new childhood obesity loci.
|
Nat Genet
|
2012
|
2.60
|
24
|
Quality, quantity and harmony: the DataSHaPER approach to integrating data across bioclinical studies.
|
Int J Epidemiol
|
2010
|
2.44
|
25
|
Variants in ADCY5 and near CCNL1 are associated with fetal growth and birth weight.
|
Nat Genet
|
2010
|
2.30
|
26
|
Decline in lung function in the Busselton Health Study: the effects of asthma and cigarette smoking.
|
Am J Respir Crit Care Med
|
2004
|
2.27
|
27
|
Genomewide linkage analysis of quantitative spirometric phenotypes in severe early-onset chronic obstructive pulmonary disease.
|
Am J Hum Genet
|
2002
|
2.23
|
28
|
The transforming growth factor-beta1 (TGFB1) gene is associated with chronic obstructive pulmonary disease (COPD).
|
Hum Mol Genet
|
2004
|
2.19
|
29
|
Association between osteopontin and human abdominal aortic aneurysm.
|
Arterioscler Thromb Vasc Biol
|
2006
|
2.14
|
30
|
Corticosteroid pharmacogenetics: association of sequence variants in CRHR1 with improved lung function in asthmatics treated with inhaled corticosteroids.
|
Hum Mol Genet
|
2004
|
2.14
|
31
|
Effect of five genetic variants associated with lung function on the risk of chronic obstructive lung disease, and their joint effects on lung function.
|
Am J Respir Crit Care Med
|
2011
|
2.07
|
32
|
Transforming growth factor-beta1 promoter polymorphism C-509T is associated with asthma.
|
Am J Respir Crit Care Med
|
2003
|
1.98
|
33
|
Diminished lipoxin biosynthesis in severe asthma.
|
Am J Respir Crit Care Med
|
2005
|
1.87
|
34
|
Endothelial nitric oxide synthase variants in cystic fibrosis lung disease.
|
Am J Respir Crit Care Med
|
2002
|
1.87
|
35
|
Association between common variation at the FTO locus and changes in body mass index from infancy to late childhood: the complex nature of genetic association through growth and development.
|
PLoS Genet
|
2011
|
1.82
|
36
|
Single-nucleotide polymorphisms in the Toll-like receptor 9 gene (TLR9): frequencies, pairwise linkage disequilibrium, and haplotypes in three U.S. ethnic groups and exploratory case-control disease association studies.
|
Genomics
|
2003
|
1.74
|
37
|
A genome-wide association search for type 2 diabetes genes in African Americans.
|
PLoS One
|
2012
|
1.72
|
38
|
Toward a roadmap in global biobanking for health.
|
Eur J Hum Genet
|
2012
|
1.65
|
39
|
Single nucleotide polymorphisms in innate immunity genes: abundant variation and potential role in complex human disease.
|
Immunol Rev
|
2002
|
1.65
|
40
|
Fine mapping versus replication in whole-genome association studies.
|
Am J Hum Genet
|
2007
|
1.64
|
41
|
Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis.
|
Nat Genet
|
2011
|
1.60
|
42
|
The relationship between infant airway function, childhood airway responsiveness, and asthma.
|
Am J Respir Crit Care Med
|
2004
|
1.58
|
43
|
Genetic variants associated with increased risk of malignant pleural mesothelioma: a genome-wide association study.
|
PLoS One
|
2013
|
1.55
|
44
|
JLIN: a java based linkage disequilibrium plotter.
|
BMC Bioinformatics
|
2006
|
1.51
|
45
|
Common variants at 6q22 and 17q21 are associated with intracranial volume.
|
Nat Genet
|
2012
|
1.51
|
46
|
Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction.
|
Am J Respir Crit Care Med
|
2012
|
1.49
|
47
|
Analyses of associations with asthma in four asthma population samples from Canada and Australia.
|
Hum Genet
|
2009
|
1.48
|
48
|
Impact of common variation in bone-related genes on type 2 diabetes and related traits.
|
Diabetes
|
2012
|
1.42
|
49
|
Genome-wide linkage analysis of severe, early-onset chronic obstructive pulmonary disease: airflow obstruction and chronic bronchitis phenotypes.
|
Hum Mol Genet
|
2002
|
1.36
|
50
|
Sex differences in the association of regional fat distribution with the severity of obstructive sleep apnea.
|
Sleep
|
2010
|
1.34
|
51
|
Meta-analysis of genome-wide linkage studies in BMI and obesity.
|
Obesity (Silver Spring)
|
2007
|
1.32
|
52
|
Association of genetic Loci with glucose levels in childhood and adolescence: a meta-analysis of over 6,000 children.
|
Diabetes
|
2011
|
1.31
|
53
|
The association of C-reactive protein and CRP genotype with coronary heart disease: findings from five studies with 4,610 cases amongst 18,637 participants.
|
PLoS One
|
2008
|
1.28
|
54
|
Sequence variants in three loci influence monocyte counts and erythrocyte volume.
|
Am J Hum Genet
|
2009
|
1.28
|
55
|
Asthma and genes encoding components of the vitamin D pathway.
|
Respir Res
|
2009
|
1.26
|
56
|
Polymorphisms in toll-like receptor 4 are not associated with asthma or atopy-related phenotypes.
|
Am J Respir Crit Care Med
|
2002
|
1.22
|
57
|
Separating the mechanism-based and off-target actions of cholesteryl ester transfer protein inhibitors with CETP gene polymorphisms.
|
Circulation
|
2009
|
1.20
|
58
|
Genome-wide association and longitudinal analyses reveal genetic loci linking pubertal height growth, pubertal timing and childhood adiposity.
|
Hum Mol Genet
|
2013
|
1.19
|
59
|
Constitutive and cytokine-induced expression of the ETS transcription factor ESE-3 in the lung.
|
Am J Respir Cell Mol Biol
|
2002
|
1.16
|
60
|
A comprehensive evaluation of potential lung function associated genes in the SpiroMeta general population sample.
|
PLoS One
|
2011
|
1.13
|
61
|
Loosening the cuff: important new advances in modeling antihypertensive treatment effects in genetic studies of hypertension.
|
Hypertension
|
2003
|
1.08
|
62
|
Relation between tumour necrosis factor polymorphism TNFalpha-308 and risk of asthma.
|
Eur J Hum Genet
|
2002
|
1.07
|
63
|
SimHap GUI: an intuitive graphical user interface for genetic association analysis.
|
BMC Bioinformatics
|
2008
|
1.06
|
64
|
Infants with flow limitation at 4 weeks: outcome at 6 and 11 years.
|
Am J Respir Crit Care Med
|
2002
|
1.05
|
65
|
A comprehensive investigation of variants in genes encoding adiponectin (ADIPOQ) and its receptors (ADIPOR1/R2), and their association with serum adiponectin, type 2 diabetes, insulin resistance and the metabolic syndrome.
|
BMC Med Genet
|
2013
|
1.04
|
66
|
Obstructive Sleep Apnoea: From pathogenesis to treatment: Current controversies and future directions.
|
Respirology
|
2010
|
1.00
|
67
|
The apolipoprotein AII rs5082 variant is associated with reduced risk of coronary artery disease in an Australian male population.
|
Atherosclerosis
|
2008
|
0.99
|
68
|
Complement factor H Y402H and C-reactive protein polymorphism and photodynamic therapy response in age-related macular degeneration.
|
Ophthalmology
|
2009
|
0.99
|
69
|
High prevalence of undiagnosed obstructive sleep apnoea in the general population and methods for screening for representative controls.
|
Sleep Breath
|
2012
|
0.96
|
70
|
Association of a body mass index genetic risk score with growth throughout childhood and adolescence.
|
PLoS One
|
2013
|
0.96
|
71
|
Covariance components models for longitudinal family data.
|
Int J Epidemiol
|
2005
|
0.96
|
72
|
Single-nucleotide polymorphisms in the interleukin-10 gene: differences in frequencies, linkage disequilibrium patterns, and haplotypes in three United States ethnic groups.
|
Genomics
|
2002
|
0.95
|
73
|
Association of a missense mutation in the NOS3 gene with exhaled nitric oxide levels.
|
Am J Respir Crit Care Med
|
2003
|
0.93
|
74
|
Postdisaster emotional distress, depression and event-related variables: findings across child and adolescent developmental stages.
|
Aust N Z J Psychiatry
|
2002
|
0.92
|
75
|
Association of an allele on chromosome 9 and abdominal aortic aneurysm.
|
Atherosclerosis
|
2010
|
0.91
|
76
|
Association of an allelic variant of interleukin-6 with subclinical carotid atherosclerosis in an Australian community population.
|
Eur Heart J
|
2003
|
0.90
|
77
|
Cholesteryl ester transfer protein gene haplotypes, plasma high-density lipoprotein levels and the risk of coronary heart disease.
|
Hum Genet
|
2007
|
0.90
|
78
|
Association between liver-specific gene polymorphisms and their expression levels with nonalcoholic fatty liver disease.
|
Hepatology
|
2013
|
0.89
|
79
|
Apolipoprotein E genotype is associated with serum C-reactive protein but not abdominal aortic aneurysm.
|
Atherosclerosis
|
2009
|
0.89
|
80
|
Comprehensive analysis of tagging sequence variants in DTNBP1 shows no association with schizophrenia or with its composite neurocognitive endophenotypes.
|
Am J Med Genet B Neuropsychiatr Genet
|
2008
|
0.89
|
81
|
Association of PPARgamma allelic variation, osteoprotegerin and abdominal aortic aneurysm.
|
Clin Endocrinol (Oxf)
|
2009
|
0.87
|
82
|
Relationship between obstructive sleep apnea and diurnal leptin rhythms.
|
Sleep
|
2004
|
0.87
|
83
|
Variants near CCNL1/LEKR1 and in ADCY5 and fetal growth characteristics in different trimesters.
|
J Clin Endocrinol Metab
|
2011
|
0.87
|
84
|
Excessive daytime sleepiness increases the risk of motor vehicle crash in obstructive sleep apnea.
|
J Clin Sleep Med
|
2013
|
0.87
|
85
|
Hospitalisation with infection, asthma and allergy in Kawasaki disease patients and their families: genealogical analysis using linked population data.
|
PLoS One
|
2011
|
0.86
|
86
|
Cholesteryl ester transfer protein gene polymorphisms increase the risk of fatty liver in females independent of adiposity.
|
J Gastroenterol Hepatol
|
2012
|
0.85
|
87
|
Apolipoprotein E gene polymorphisms are associated with carotid plaque formation but not with intima-media wall thickening: results from the Perth Carotid Ultrasound Disease Assessment Study (CUDAS).
|
Stroke
|
2003
|
0.85
|
88
|
Prenatal, perinatal, and heritable influences on cord blood immune responses.
|
Ann Allergy Asthma Immunol
|
2006
|
0.85
|
89
|
Neurophysiological evidence for cognitive and brain functional adaptation in adolescents living at high altitude.
|
Clin Neurophysiol
|
2011
|
0.85
|
90
|
Genetic influences on trajectories of systolic blood pressure across childhood and adolescence.
|
Circ Cardiovasc Genet
|
2013
|
0.84
|
91
|
15-Lipoxygenase gene variants are associated with carotid plaque but not carotid intima-media thickness.
|
Hum Genet
|
2008
|
0.84
|
92
|
Modelling BMI trajectories in children for genetic association studies.
|
PLoS One
|
2013
|
0.84
|
93
|
Make it HuGE: human genome epidemiology reviews, population health, and the IJE.
|
Int J Epidemiol
|
2006
|
0.83
|
94
|
Nuclear factor kappa B activation in human cord blood mononuclear cells.
|
Pediatr Res
|
2004
|
0.83
|
95
|
DNA sequence variants in epithelium-specific ETS-2 and ETS-3 are not associated with asthma.
|
Am J Respir Crit Care Med
|
2002
|
0.83
|
96
|
Association of Interleukin-1 gene polymorphisms with central obesity and metabolic syndrome in a coronary heart disease population.
|
Hum Genet
|
2008
|
0.83
|
97
|
Celestial3D: a novel method for 3D visualization of familial data.
|
Bioinformatics
|
2008
|
0.82
|
98
|
Angiotensinogen gene T235 variant: a marker for the development of persistent microalbuminuria in children and adolescents with type 1 diabetes mellitus.
|
J Diabetes Complications
|
2008
|
0.82
|
99
|
Rationale, design and methods for a community-based study of clustering and cumulative effects of chronic disease processes and their effects on ageing: the Busselton healthy ageing study.
|
BMC Public Health
|
2013
|
0.81
|
100
|
Smoking status and occupational exposure affects oxidative DNA injury in boilermakers exposed to metal fume and residual oil fly ash.
|
Cancer Epidemiol Biomarkers Prev
|
2004
|
0.81
|
101
|
1-hydroxypyrene as a biomarker of occupational exposure to polycyclic aromatic hydrocarbons (PAH) in boilermakers.
|
J Occup Environ Med
|
2002
|
0.81
|
102
|
Association of PARL rs3732581 genetic variant with insulin levels, metabolic syndrome and coronary artery disease.
|
Hum Genet
|
2008
|
0.81
|
103
|
The effect of missing data on linkage disequilibrium mapping and haplotype association analysis in the GAW14 simulated datasets.
|
BMC Genet
|
2005
|
0.81
|
104
|
Associations of cord blood fatty acids with lymphocyte proliferation, IL-13, and IFN-gamma.
|
J Allergy Clin Immunol
|
2006
|
0.81
|
105
|
Urinary metal and polycyclic aromatic hydrocarbon biomarkers in boilermakers exposed to metal fume and residual oil fly ash.
|
Am J Ind Med
|
2005
|
0.81
|
106
|
Investigating the association between K198N coding polymorphism in EDN1 and hypertension, lipoprotein levels, the metabolic syndrome and cardiovascular disease.
|
Hum Genet
|
2008
|
0.81
|
107
|
A single-nucleotide polymorphism in the gene encoding osteoprotegerin is associated with diastolic blood pressure in older men.
|
Am J Hypertens
|
2009
|
0.80
|
108
|
Stromelysin-1 (MMP-3) gene 5A/6A promoter polymorphism is associated with blood pressure in a community population.
|
J Hypertens
|
2005
|
0.80
|
109
|
A population-based study of polymorphisms in genes related to sex hormones and abdominal aortic aneurysm.
|
Eur J Hum Genet
|
2010
|
0.78
|
110
|
The longitudinal association of common susceptibility variants for type 2 diabetes and obesity with fasting glucose level and BMI.
|
BMC Med Genet
|
2010
|
0.78
|
111
|
Effectiveness of individual-focused interventions to prevent chronic disease.
|
Eur J Clin Invest
|
2014
|
0.77
|
112
|
A vision for chronic disease prevention intervention research: report from a workshop.
|
Can J Public Health
|
2014
|
0.77
|
113
|
International Genome-Wide Association Study Consortium Identifies Novel Loci Associated With Blood Pressure in Children and Adolescents.
|
Circ Cardiovasc Genet
|
2016
|
0.77
|
114
|
The role of prostaglandin D receptor gene in asthma pathogenesis.
|
Am J Respir Cell Mol Biol
|
2005
|
0.77
|
115
|
A genome-wide association study for malignant mesothelioma risk.
|
Lung Cancer
|
2013
|
0.77
|
116
|
Functional haplotypes in the PTGDR gene fail to associate with asthma in two Australian populations.
|
Respirology
|
2011
|
0.76
|
117
|
Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.
|
PLoS Genet
|
2016
|
0.75
|
118
|
Lack of reproducibility of linkage results in serially measured blood pressure data.
|
BMC Genet
|
2003
|
0.75
|
119
|
Genome-wide association study to identify common variants associated with brachial circumference: a meta-analysis of 14 cohorts.
|
PLoS One
|
2012
|
0.75
|
120
|
Correction: genetic variants associated with increased risk of malignant pleural mesothelioma: a genome-wide association study.
|
PLoS One
|
2015
|
0.75
|
121
|
Response to Epstein et al.
|
Am J Hum Genet
|
2002
|
0.75
|
122
|
Genome-wide linkage and association mapping of disease genes with the GAW14 simulated datasets.
|
BMC Genet
|
2005
|
0.75
|
123
|
Correction: Genome-wide physical activity interactions in adiposity - A meta-analysis of 200,452 adults.
|
PLoS Genet
|
2017
|
0.75
|
124
|
Associations between anxious-depressed symptoms and cardiovascular risk factors in a longitudinal childhood study.
|
Prev Med
|
2012
|
0.75
|
125
|
Respiratory infections and lung function in an Australian Aboriginal community.
|
Respirology
|
2008
|
0.75
|
126
|
The Western Australian Melanoma Health Study: study design and participant characteristics.
|
Cancer Epidemiol
|
2011
|
0.75
|
127
|
The Western Australian Twin Register: a population-based register of adult and child multiples.
|
Twin Res Hum Genet
|
2006
|
0.75
|
128
|
The New Epidemiology: putting the pieces together in complex disease aetiology.
|
Int J Epidemiol
|
2004
|
0.75
|