Aimo Ruokonen

Author PubWeight™ 242.80‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Biological, clinical and population relevance of 95 loci for blood lipids. Nature 2010 28.21
2 Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet 2010 23.08
3 Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat Genet 2008 22.35
4 New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet 2010 17.89
5 Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts. Nat Genet 2008 12.32
6 Genome-wide association analysis of metabolic traits in a birth cohort from a founder population. Nat Genet 2008 12.07
7 Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution. PLoS Genet 2009 5.81
8 A variant near MTNR1B is associated with increased fasting plasma glucose levels and type 2 diabetes risk. Nat Genet 2008 5.49
9 Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia. Nat Genet 2009 5.43
10 Genetic Loci associated with C-reactive protein levels and risk of coronary heart disease. JAMA 2009 5.32
11 A genome-wide association study identifies protein quantitative trait loci (pQTLs). PLoS Genet 2008 4.75
12 A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance. Nat Genet 2012 4.37
13 Genetic variants influencing circulating lipid levels and risk of coronary artery disease. Arterioscler Thromb Vasc Biol 2010 4.08
14 Common variation in the FTO gene alters diabetes-related metabolic traits to the extent expected given its effect on BMI. Diabetes 2008 3.76
15 Genetic loci influencing kidney function and chronic kidney disease. Nat Genet 2010 3.75
16 Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels. Circulation 2011 3.68
17 Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet 2012 3.21
18 Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma. Nat Genet 2011 3.18
19 New gene functions in megakaryopoiesis and platelet formation. Nature 2011 3.14
20 Common variants associated with plasma triglycerides and risk for coronary artery disease. Nat Genet 2013 2.92
21 Seventy-five genetic loci influencing the human red blood cell. Nature 2012 2.77
22 Genome-wide association study identifies variants in TMPRSS6 associated with hemoglobin levels. Nat Genet 2009 2.19
23 A genome-wide association search for type 2 diabetes genes in African Americans. PLoS One 2012 1.72
24 The role of adiposity in cardiometabolic traits: a Mendelian randomization analysis. PLoS Med 2013 1.70
25 Perinatal outcome of children born to mothers with thyroid dysfunction or antibodies: a prospective population-based cohort study. J Clin Endocrinol Metab 2008 1.69
26 Common genetic variation near melatonin receptor MTNR1B contributes to raised plasma glucose and increased risk of type 2 diabetes among Indian Asians and European Caucasians. Diabetes 2009 1.65
27 Genetic evidence that raised sex hormone binding globulin (SHBG) levels reduce the risk of type 2 diabetes. Hum Mol Genet 2009 1.61
28 Genome-wide screen for metabolic syndrome susceptibility Loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits. Circ Cardiovasc Genet 2012 1.60
29 Type 2 diabetes risk alleles are associated with reduced size at birth. Diabetes 2009 1.58
30 Co-occurrence of metabolic syndrome with depression and anxiety in young adults: the Northern Finland 1966 Birth Cohort Study. Psychosom Med 2006 1.58
31 Effects of follicle-stimulating hormone (FSH) and human chorionic gonadotropin in individuals with an inactivating mutation of the FSH receptor. Fertil Steril 2002 1.48
32 Serum anti-Müllerian hormone levels remain high until late reproductive age and decrease during metformin therapy in women with polycystic ovary syndrome. Hum Reprod 2005 1.45
33 Thyroid dysfunction and autoantibodies during pregnancy as predictive factors of pregnancy complications and maternal morbidity in later life. J Clin Endocrinol Metab 2010 1.38
34 Estimation of newborn risk for child or adolescent obesity: lessons from longitudinal birth cohorts. PLoS One 2012 1.35
35 Size at birth, weight gain over the life course, and low-grade inflammation in young adulthood: northern Finland 1966 Birth Cohort study. Eur Heart J 2008 1.32
36 Metabolic cardiovascular disease risk factors in women with self-reported symptoms of oligomenorrhea and/or hirsutism: Northern Finland Birth Cohort 1966 Study. J Clin Endocrinol Metab 2004 1.30
37 The effect of freezing, thawing, and short- and long-term storage on serum thyrotropin, thyroid hormones, and thyroid autoantibodies: implications for analyzing samples stored in serum banks. Clin Chem 2007 1.29
38 Manifestations of metabolic syndrome after hypertensive pregnancy. Hypertension 2004 1.26
39 Adolescent manifestations of metabolic syndrome among children born to women with gestational diabetes in a general-population birth cohort. Am J Epidemiol 2009 1.26
40 Metformin improves pregnancy and live-birth rates in women with polycystic ovary syndrome (PCOS): a multicenter, double-blind, placebo-controlled randomized trial. J Clin Endocrinol Metab 2012 1.25
41 A genome-wide association meta-analysis of circulating sex hormone-binding globulin reveals multiple Loci implicated in sex steroid hormone regulation. PLoS Genet 2012 1.23
42 Hormonal profile of women with self-reported symptoms of oligomenorrhea and/or hirsutism: Northern Finland birth cohort 1966 study. J Clin Endocrinol Metab 2003 1.21
43 Metformin reduces serum C-reactive protein levels in women with polycystic ovary syndrome. J Clin Endocrinol Metab 2003 1.18
44 Early pregnancy reference intervals of thyroid hormone concentrations in a thyroid antibody-negative pregnant population. Thyroid 2011 1.14
45 C-reactive protein levels and sleep disturbances: observations based on the Northern Finland 1966 Birth Cohort study. Psychosom Med 2007 1.12
46 Comparison of metabolic and inflammatory outcomes in women who used oral contraceptives and the levonorgestrel-releasing intrauterine device in a general population. Am J Obstet Gynecol 2008 1.10
47 Cardiometabolic risk factors in young adults who were born preterm. Am J Epidemiol 2015 1.04
48 Large-scale analysis of the relationship between CYP11A promoter variation, polycystic ovarian syndrome, and serum testosterone. J Clin Endocrinol Metab 2004 1.01
49 Effects of sustained insulin-induced hypoglycemia on cardiovascular autonomic regulation in type 1 diabetes. Diabetes 2005 0.97
50 Analysis of multiple data sets reveals no association between the insulin gene variable number tandem repeat element and polycystic ovary syndrome or related traits. J Clin Endocrinol Metab 2005 0.96
51 Smoking and early pregnancy thyroid hormone and anti-thyroid antibody levels in euthyroid mothers of the Northern Finland Birth Cohort 1986. Thyroid 2012 0.95
52 Metformin versus ethinyl estradiol-cyproterone acetate in the treatment of nonobese women with polycystic ovary syndrome: a randomized study. J Clin Endocrinol Metab 2003 0.94
53 Unfavorable hormonal, metabolic, and inflammatory alterations persist after menopause in women with PCOS. J Clin Endocrinol Metab 2011 0.94
54 Genomic, transcriptomic, and lipidomic profiling highlights the role of inflammation in individuals with low high-density lipoprotein cholesterol. Arterioscler Thromb Vasc Biol 2013 0.93
55 Adrenal androgen production capacity remains high up to menopause in women with polycystic ovary syndrome. J Clin Endocrinol Metab 2009 0.92
56 Variation at the insulin gene VNTR (variable number tandem repeat) polymorphism and early growth: studies in a large Finnish birth cohort. Diabetes 2004 0.91
57 Offspring's blood pressure and metabolic phenotype after exposure to gestational hypertension in utero. Eur J Epidemiol 2013 0.90
58 Antimüllerian hormone levels decrease in women using combined contraception independently of administration route. Fertil Steril 2012 0.90
59 A genome-wide association study identifies rs2000999 as a strong genetic determinant of circulating haptoglobin levels. PLoS One 2012 0.89
60 Effects of repeated whole-body cold exposures on serum concentrations of growth hormone, thyrotropin, prolactin and thyroid hormones in healthy women. Cryobiology 2009 0.89
61 Feasibility of videoconferencing in lifestyle group counselling. Int J Circumpolar Health 2010 0.89
62 Rare genomic structural variants in complex disease: lessons from the replication of associations with obesity. PLoS One 2013 0.88
63 A novel mutation of the fumarase gene in a family with autosomal recessive fumarase deficiency. J Mol Med (Berl) 2004 0.88
64 Full-length visfatin levels are associated with inflammation in women with polycystic ovary syndrome. Eur J Clin Invest 2011 0.87
65 Statin therapy worsens insulin sensitivity in women with polycystic ovary syndrome (PCOS): a prospective, randomized, double-blind, placebo-controlled study. J Clin Endocrinol Metab 2013 0.86
66 Transdermal estradiol treatment suppresses serum gonadotropins during lactation without transfer into breast milk. Fertil Steril 2004 0.85
67 Ovarian age-related responsiveness to human chorionic gonadotropin. J Clin Endocrinol Metab 2003 0.84
68 Detailed analysis of variation at and around mitochondrial position 16189 in a large Finnish cohort reveals no significant associations with early growth or metabolic phenotypes at age 31 years. J Clin Endocrinol Metab 2007 0.83
69 The impact of gestational thyroid hormone concentrations on ADHD symptoms of the child. J Clin Endocrinol Metab 2013 0.83
70 Weight at birth and infancy in relation to adult leukocyte count: a population-based study of 5619 men and women followed from the fetal period to adulthood. J Clin Endocrinol Metab 2009 0.83
71 Seasonal levels of melatonin, thyroid hormones, mood, and cognition near the Arctic Circle. Aviat Space Environ Med 2008 0.82
72 Maternal Hb during pregnancy and offspring's educational achievement: a prospective cohort study over 30 years. Br J Nutr 2010 0.82
73 Relationship between E23K (an established type II diabetes-susceptibility variant within KCNJ11), polycystic ovary syndrome and androgen levels. Eur J Hum Genet 2007 0.81
74 Rosiglitazone treatment alleviates inflammation and improves liver function in overweight women with polycystic ovary syndrome: a randomized placebo-controlled study. Fertil Steril 2006 0.81
75 Association of abnormal glucose tolerance with self-reported sleep apnea among a 57-year-old urban population in Northern Finland. Diabetes Res Clin Pract 2008 0.81
76 Ovarian response to the human chorionic gonadotrophin stimulation test in normal ovulatory women: the impact of regressing corpus luteum. Fertil Steril 2007 0.79
77 Gene-targeted analysis of copy number variants identifies 3 novel associations with coronary heart disease traits. Circ Cardiovasc Genet 2012 0.79
78 Effect of rising hCG levels on the human corpus luteum during early pregnancy. Hum Reprod 2008 0.79
79 Ovarian age-related responsiveness to human chorionic gonadotropin in women with polycystic ovary syndrome. J Clin Endocrinol Metab 2004 0.78
80 Lack of physiological suppression of circulating IGFBP-1 in puberty in patients with insulin-dependent diabetes mellitus. Eur J Endocrinol 2002 0.78
81 Maternal thyroid dysfunction during pregnancy and thyroid function of her child in adolescence. J Clin Endocrinol Metab 2013 0.77
82 Preeclampsia, gestational hypertension and subsequent hypothyroidism. Pregnancy Hypertens 2012 0.77
83 Thyroid hormones are stable even during prolonged frozen storage. Clin Chem Lab Med 2010 0.75
84 Metabolic and reproductive characteristics of first-degree relatives of women with self-reported oligo-amenorrhoea and hirsutism. Gynecol Endocrinol 2010 0.75
85 Fitness, Fatness, Physical Activity, and Autonomic Function in Midlife. Med Sci Sports Exerc 2017 0.75
86 Associations of microalbuminuria and blood pressure with carotid, aortic and femoral atheromatous plaques in elderly Finns. Diabetes Res Clin Pract 2005 0.75
87 The Association Between Low Grade Systemic Inflammation and Skin Diseases: A Cross-sectional Survey in the Northern Finland Birth Cohort 1966. Acta Derm Venereol 2017 0.75