Published in Mol Immunol on January 22, 2010
Chimeric anti-CD14 IGG2/4 Hybrid antibodies for therapeutic intervention in pig and human models of inflammation. J Immunol (2013) 0.87
Secretory phospholipase A2 pathway in various types of lung injury in neonates and infants: a multicentre translational study. BMC Pediatr (2011) 0.79
Immune profiling of BALB/C and C57BL/6 mice reveals a correlation between Ureaplasma parvum-Induced fetal inflammatory response syndrome-like pathology and increased placental expression of TLR2 and CD14. Am J Reprod Immunol (2013) 0.76
Meconium-induced inflammation and surfactant inactivation: specifics of molecular mechanisms. Pediatr Res (2015) 0.75
NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals. Nature (2010) 10.60
TLR9 signals after translocating from the ER to CpG DNA in the lysosome. Nat Immunol (2004) 8.06
Toll-like receptor 4 and high-mobility group box-1 are involved in ictogenesis and can be targeted to reduce seizures. Nat Med (2010) 4.61
Ligand-induced conformational changes allosterically activate Toll-like receptor 9. Nat Immunol (2007) 4.09
The NLRP3 inflammasome is up-regulated in cardiac fibroblasts and mediates myocardial ischaemia-reperfusion injury. Cardiovasc Res (2013) 3.92
The proinflammatory CD14+CD16+DR++ monocytes are a major source of TNF. J Immunol (2002) 3.75
Lipopolysaccharide rapidly traffics to and from the Golgi apparatus with the toll-like receptor 4-MD-2-CD14 complex in a process that is distinct from the initiation of signal transduction. J Biol Chem (2002) 3.58
Endocytic pathways regulate Toll-like receptor 4 signaling and link innate and adaptive immunity. EMBO J (2006) 3.07
Maternal supplementation with very-long-chain n-3 fatty acids during pregnancy and lactation augments children's IQ at 4 years of age. Pediatrics (2003) 2.86
A novel host-parasite lipid cross-talk. Schistosomal lyso-phosphatidylserine activates toll-like receptor 2 and affects immune polarization. J Biol Chem (2002) 2.61
Inflammatory response after open heart surgery: release of heat-shock protein 70 and signaling through toll-like receptor-4. Circulation (2002) 2.44
The Rab11a GTPase controls Toll-like receptor 4-induced activation of interferon regulatory factor-3 on phagosomes. Immunity (2010) 2.29
Rewarming after hypothermia after cardiac arrest shifts the inflammatory balance. Crit Care Med (2012) 2.26
Setting research priorities to reduce almost one million deaths from birth asphyxia by 2015. PLoS Med (2011) 2.01
Effects of a complex mixture of therapeutic drugs at environmental levels on human embryonic cells. Environ Sci Technol (2006) 1.97
European consensus guidelines on the management of neonatal respiratory distress syndrome in preterm infants--2013 update. Neonatology (2013) 1.96
Lysines 128 and 132 enable lipopolysaccharide binding to MD-2, leading to Toll-like receptor-4 aggregation and signal transduction. J Biol Chem (2003) 1.78
European consensus guidelines on the management of neonatal respiratory distress syndrome in preterm infants - 2010 update. Neonatology (2010) 1.72
Toll-like receptor 3 associates with c-Src tyrosine kinase on endosomes to initiate antiviral signaling. EMBO J (2006) 1.72
Increased systemic and myocardial expression of neutrophil gelatinase-associated lipocalin in clinical and experimental heart failure. Eur Heart J (2009) 1.71
Planned cesarean versus planned vaginal delivery at term: comparison of newborn infant outcomes. Am J Obstet Gynecol (2006) 1.66
Cellular trafficking of lipoteichoic acid and Toll-like receptor 2 in relation to signaling: role of CD14 and CD36. J Leukoc Biol (2008) 1.61
Complement inhibition decreases the procoagulant response and confers organ protection in a baboon model of Escherichia coli sepsis. Blood (2010) 1.56
TAG, a splice variant of the adaptor TRAM, negatively regulates the adaptor MyD88-independent TLR4 pathway. Nat Immunol (2009) 1.52
Effect of perfusion temperature on the inflammatory response during pediatric cardiac surgery. Ann Thorac Surg (2008) 1.52
Population and disease-based prevalence of the common mutations associated with surfactant deficiency. Pediatr Res (2008) 1.35
An international serum standard for application in assays to detect human complement activation products. Mol Immunol (2013) 1.34
Reduction in neonatal mortality in Chile between 1990 and 2000. Pediatrics (2006) 1.33
Importance of extra- and intracellular domains of TLR1 and TLR2 in NFkappa B signaling. J Cell Biol (2003) 1.32
Effect of supplementing pregnant and lactating mothers with n-3 very-long-chain fatty acids on children's IQ and body mass index at 7 years of age. Pediatrics (2008) 1.23
Binding of lipopeptide to CD14 induces physical proximity of CD14, TLR2 and TLR1. Eur J Immunol (2005) 1.22
Involvement of toll-like receptor (TLR) 2 and TLR4 in cell activation by mannuronic acid polymers. J Biol Chem (2002) 1.16
Melanoma cell lines are responsive in vitro to lipopolysaccharide and express TLR-4. Cancer Lett (2006) 1.15
Cholesterol crystals induce complement-dependent inflammasome activation and cytokine release. J Immunol (2014) 1.15
Inhibition of C5a-induced inflammation with preserved C5b-9-mediated bactericidal activity in a human whole blood model of meningococcal sepsis. Blood (2003) 1.14
Cutting edge: link between innate and adaptive immunity: Toll-like receptor 2 internalizes antigen for presentation to CD4+ T cells and could be an efficient vaccine target. J Immunol (2003) 1.13
The role of complement C3 opsonization, C5a receptor, and CD14 in E. coli-induced up-regulation of granulocyte and monocyte CD11b/CD18 (CR3), phagocytosis, and oxidative burst in human whole blood. J Leukoc Biol (2007) 1.11
Toll-like receptor-mediated tumor necrosis factor and interleukin-10 production differ during systemic inflammation. Am J Respir Crit Care Med (2003) 1.11
Increased expression of toll-like receptor 2 on monocytes in HIV infection: possible roles in inflammation and viral replication. Clin Infect Dis (2004) 1.11
Resuscitation with 100% O2 increases cerebral injury in hypoxemic piglets. Pediatr Res (2004) 1.11
The GOLD domain-containing protein TMED7 inhibits TLR4 signalling from the endosome upon LPS stimulation. Nat Commun (2012) 1.09
Metabolomic analyses of plasma reveals new insights into asphyxia and resuscitation in pigs. PLoS One (2010) 1.08
Mechanism of complement activation and its role in the inflammatory response after thoracoabdominal aortic aneurysm repair. Circulation (2003) 1.07
Hypothesis: combined inhibition of complement and CD14 as treatment regimen to attenuate the inflammatory response. Adv Exp Med Biol (2008) 1.07
Variants of developmental genes (TGFA, TGFB3, and MSX1) and their associations with orofacial clefts: a case-parent triad analysis. Genet Epidemiol (2003) 1.06
Intracellular Mycobacterium avium intersect transferrin in the Rab11(+) recycling endocytic pathway and avoid lipocalin 2 trafficking to the lysosomal pathway. J Infect Dis (2010) 1.06
Induction of cytokine production in human T cells and monocytes by highly purified lipoteichoic acid: involvement of Toll-like receptors and CD14. Med Sci Monit (2002) 1.06
A cyanobacterial LPS antagonist prevents endotoxin shock and blocks sustained TLR4 stimulation required for cytokine expression. J Exp Med (2006) 1.06
Antibody repertoire development in teleosts--a review with emphasis on salmonids and Gadus morhua L. Dev Comp Immunol (2006) 1.05
Managing oxygen therapy during delivery room stabilization of preterm infants. J Pediatr (2011) 1.05
Endonuclease VIII-like 3 (Neil3) DNA glycosylase promotes neurogenesis induced by hypoxia-ischemia. Proc Natl Acad Sci U S A (2011) 1.04
On-pump versus off-pump coronary artery bypass grafting: more heat-shock protein 70 is released after on-pump surgery. Eur J Cardiothorac Surg (2004) 1.03
Neutrophil gelatinase-associated lipocalin: a biomarker in COPD. Chest (2010) 1.03
Biomarker profile in off-pump and on-pump coronary artery bypass grafting surgery in low-risk patients. Ann Thorac Surg (2008) 1.02
Lipopolysaccharide and double-stranded RNA up-regulate toll-like receptor 2 independently of myeloid differentiation factor 88. J Biol Chem (2004) 0.99
Cellular sources and inducers of cytokines present in acute wound fluid. Wound Repair Regen (2011) 0.99
The LPS receptor generates inflammatory signals from the cell surface. J Endotoxin Res (2003) 0.99
Interactions between intracellular Na+ levels and saxitoxin production in Cylindrospermopsis raciborskii T3. Microbiology (2004) 0.99
Mechanisms of TLR9 activation. J Endotoxin Res (2004) 0.99
Whole genome gene expression meta-analysis of inflammatory bowel disease colon mucosa demonstrates lack of major differences between Crohn's disease and ulcerative colitis. PLoS One (2013) 0.98
Enhanced expression of CXCL10 in inflammatory bowel disease: potential role of mucosal Toll-like receptor 3 stimulation. Inflamm Bowel Dis (2013) 0.98
Alginate microbeads are complement compatible, in contrast to polycation containing microcapsules, as revealed in a human whole blood model. Acta Biomater (2011) 0.97
Non-healing is associated with persistent stimulation of the innate immune response in chronic venous leg ulcers. J Dermatol Sci (2010) 0.96
Exercise reduces plasma levels of the chemokines MCP-1 and IL-8 in subjects with the metabolic syndrome. Eur Heart J (2004) 0.96
Therapeutic potential of new antiinflammatory drugs. Epilepsia (2011) 0.95
Development, characterization and use of monoclonal antibodies against sTRAIL: measurement of sTRAIL by ELISA. J Immunol Methods (2002) 0.95
Effect of supraphysiologic levels of C1-inhibitor on the classical, lectin and alternative pathways of complement. Mol Immunol (2006) 0.94
Stages of meningococcal sepsis simulated in vitro, with emphasis on complement and Toll-like receptor activation. Infect Immun (2008) 0.94
Tolerance induced by the lipopeptide Pam3Cys is due to ablation of IL-1R-associated kinase-1. J Immunol (2004) 0.94
Cleft palate, transforming growth factor alpha gene variants, and maternal exposures: assessing gene-environment interactions in case-parent triads. Genet Epidemiol (2003) 0.94
Neuroprotective effects of toll-like receptor 4 antagonism in spinal cord cultures and in a mouse model of motor neuron degeneration. Mol Med (2012) 0.94
Supplementation of n-3 fatty acids during pregnancy and lactation reduces maternal plasma lipid levels and provides DHA to the infants. J Matern Fetal Neonatal Med (2006) 0.93
IL-10 enhances MD-2 and CD14 expression in monocytes and the proteins are increased and correlated in HIV-infected patients. J Immunol (2009) 0.93
Visualization of alginate-poly-L-lysine-alginate microcapsules by confocal laser scanning microscopy. Biotechnol Bioeng (2003) 0.93
Extended series of cardiac compressions during CPR in a swine model of perinatal asphyxia. Resuscitation (2010) 0.92
Cell-compatible covalently reinforced beads obtained from a chemoenzymatically engineered alginate. Biomaterials (2006) 0.91
Soluble toll-like receptor 2 in HIV infection: association with disease progression. AIDS (2004) 0.91
Pathway-specific complement activity in pigs evaluated with a human functional complement assay. Mol Immunol (2009) 0.90
Reoxygenation with 100 or 21% oxygen after cerebral hypoxemia-ischemia-hypercapnia in newborn piglets. Biol Neonate (2003) 0.90
Gene expression profiling in preterm infants: new aspects of bronchopulmonary dysplasia development. PLoS One (2013) 0.90
Return of spontaneous circulation with a compression:ventilation ratio of 15:2 versus 3:1 in newborn pigs with cardiac arrest due to asphyxia. Arch Dis Child Fetal Neonatal Ed (2011) 0.90
Higher order structure of short immunostimulatory oligonucleotides studied by atomic force microscopy. Ultramicroscopy (2010) 0.90
Policy benchmarking report on neonatal health and social policies in 13 European countries. Acta Paediatr (2010) 0.89
Low mannose-binding lectin and increased complement activation correlate to allograft vasculopathy, ischaemia, and rejection after human heart transplantation. Eur Heart J (2005) 0.89
Combined inhibition of complement and CD14 efficiently attenuated the inflammatory response induced by Staphylococcus aureus in a human whole blood model. J Immunol (2014) 0.89
Increased systemic and local interleukin 9 levels in patients with carotid and coronary atherosclerosis. PLoS One (2013) 0.89
A proviral role for CpG in cytomegalovirus infection. J Immunol (2009) 0.89
Resuscitation of severely asphyctic newborn pigs with cardiac arrest by using 21% or 100% oxygen. Neonatology (2010) 0.88
Excessive innate immune response and mutant D222G/N in severe A (H1N1) pandemic influenza. J Infect (2011) 0.88
Relative chemokine and adhesion molecule expression in Mediterranean spotted fever and African tick bite fever. J Infect (2008) 0.88
Combined inhibition of complement C5 and CD14 markedly attenuates inflammation, thrombogenicity, and hemodynamic changes in porcine sepsis. J Immunol (2013) 0.88
Bride and groom in systemic inflammation--the bells ring for complement and Toll in cooperation. Immunobiology (2012) 0.87
Chimeric anti-CD14 IGG2/4 Hybrid antibodies for therapeutic intervention in pig and human models of inflammation. J Immunol (2013) 0.87