Published in Carcinogenesis on January 21, 2010
Ursodeoxycholic acid treatment in a rat model of cancer cachexia. J Cachexia Sarcopenia Muscle (2011) 1.06
Ciliary subcellular localization of TGR5 determines the cholangiocyte functional response to bile acid signaling. Am J Physiol Gastrointest Liver Physiol (2013) 0.94
Ursodeoxycholic acid but not tauroursodeoxycholic acid inhibits proliferation and differentiation of human subcutaneous adipocytes. PLoS One (2013) 0.78
Bile acids inhibit Na⁺/H⁺ exchanger and Cl⁻/HCO₃⁻ exchanger activities via cellular energy breakdown and Ca²⁺ overload in human colonic crypts. Pflugers Arch (2015) 0.77
Golgi phosphoprotein 2 (GOLPH2) is a novel bile acid-responsive modulator of oesophageal cell migration and invasion. Br J Cancer (2015) 0.76
Unconjugated secondary bile acids activate the unfolded protein response and induce golgi fragmentation via a src-kinase-dependant mechanism. Oncotarget (2016) 0.75
A genome-wide association study for celiac disease identifies risk variants in the region harboring IL2 and IL21. Nat Genet (2007) 8.50
Newly identified genetic risk variants for celiac disease related to the immune response. Nat Genet (2008) 7.63
Multiple common variants for celiac disease influencing immune gene expression. Nat Genet (2010) 6.90
Statistical methods for analysis of high-throughput RNA interference screens. Nat Methods (2009) 4.76
Barrett esophagus: prevalence of central adiposity, metabolic syndrome, and a proinflammatory state. Ann Surg (2008) 2.30
Distinct MHC class I and II alleles are associated with hepatitis C viral clearance, originating from a single source. Hepatology (2004) 2.12
Polymorphisms in melanoma differentiation-associated gene 5 link protein function to clearance of hepatitis C virus. Hepatology (2015) 2.11
Pharmacological disruption of calcium channel trafficking by the alpha2delta ligand gabapentin. Proc Natl Acad Sci U S A (2008) 2.04
Dominant influence of an HLA-B27 restricted CD8+ T cell response in mediating HCV clearance and evolution. Hepatology (2006) 1.96
PI3K promotes voltage-dependent calcium channel trafficking to the plasma membrane. Nat Neurosci (2004) 1.93
Heterogeneity of tumor-induced gene expression changes in the human metabolic network. Nat Biotechnol (2013) 1.91
Development and independent validation of a prognostic assay for stage II colon cancer using formalin-fixed paraffin-embedded tissue. J Clin Oncol (2011) 1.84
Primary sclerosing cholangitis and disease distribution in inflammatory bowel disease. Clin Gastroenterol Hepatol (2011) 1.77
Assessment of fibrosis progression in untreated irish women with chronic hepatitis C contracted from immunoglobulin anti-D. Clin Gastroenterol Hepatol (2006) 1.66
Tumor budding is a strong and reproducible prognostic marker in T3N0 colorectal cancer. Am J Surg Pathol (2009) 1.63
Coagulopathy after cardiac surgery may be influenced by a functional plasminogen activator inhibitor polymorphism. Anesth Analg (2007) 1.49
Loss of viral fitness and cross-recognition by CD8+ T cells limit HCV escape from a protective HLA-B27-restricted human immune response. J Clin Invest (2009) 1.46
A role for TLR4 in Clostridium difficile infection and the recognition of surface layer proteins. PLoS Pathog (2011) 1.39
The pregnane X receptor locus is associated with susceptibility to inflammatory bowel disease. Gastroenterology (2006) 1.39
Nonfunctionalized nanocrystals can exploit a cell's active transport machinery delivering them to specific nuclear and cytoplasmic compartments. Nano Lett (2007) 1.37
Efficient generation and cryopreservation of cardiomyocytes derived from human embryonic stem cells. Regen Med (2011) 1.35
NF-kappaB activation in esophageal adenocarcinoma: relationship to Barrett's metaplasia, survival, and response to neoadjuvant chemoradiotherapy. Ann Surg (2004) 1.31
Association of NOD2 with Crohn's disease in a homogenous Irish population. Eur J Hum Genet (2003) 1.30
Estimating the net contribution of interleukin-28B variation to spontaneous hepatitis C virus clearance. Hepatology (2011) 1.30
NF-kappaB regulation: the nuclear response. J Cell Mol Med (2009) 1.27
Dominant-negative calcium channel suppression by truncated constructs involves a kinase implicated in the unfolded protein response. J Neurosci (2004) 1.25
The ducky mutation in Cacna2d2 results in altered Purkinje cell morphology and is associated with the expression of a truncated alpha 2 delta-2 protein with abnormal function. J Biol Chem (2001) 1.21
Generation of an epigenetic signature by chronic hypoxia in prostate cells. Hum Mol Genet (2009) 1.21
Inflammation and esophageal carcinogenesis. Curr Opin Pharmacol (2009) 1.17
A survey of breast cancer awareness and knowledge in a Western population: lots of light but little illumination. Eur J Cancer (2005) 1.16
Effect of immune pressure on hepatitis C virus evolution: insights from a single-source outbreak. Hepatology (2011) 1.14
STAT3-stathmin interactions control microtubule dynamics in migrating T-cells. J Biol Chem (2009) 1.13
Angiogenesis and blood vessel stability in inflammatory arthritis. Arthritis Rheum (2010) 1.13
Collagenous sprue: a clinicopathologic study of 12 cases. Am J Surg Pathol (2009) 1.13
Conjugated linoleic acid suppresses NF-kappa B activation and IL-12 production in dendritic cells through ERK-mediated IL-10 induction. J Immunol (2005) 1.11
N terminus is key to the dominant negative suppression of Ca(V)2 calcium channels: implications for episodic ataxia type 2. J Biol Chem (2009) 1.11
Childhood Helicobacter pylori infection and growth impairment in developing countries: a vicious cycle? Pediatrics (2007) 1.08
Identification of a mutation in LARS as a novel cause of infantile hepatopathy. Mol Genet Metab (2012) 1.08
Localization of nuclear cathepsin L and its association with disease progression and poor outcome in colorectal cancer. Int J Cancer (2009) 1.06
Sequence and phylogenetic analysis of the gene for surface layer protein, slpA, from 14 PCR ribotypes of Clostridium difficile. J Med Microbiol (2006) 1.05
L-plastin regulates polarization and migration in chemokine-stimulated human T lymphocytes. J Immunol (2012) 1.05
Medullary carcinoma of the pancreas in a man with hereditary nonpolyposis colorectal cancer due to a mutation of the MSH2 mismatch repair gene. Hum Pathol (2006) 1.02
Decreased mitochondrial DNA mutagenesis in human colorectal cancer. PLoS Genet (2012) 1.02
Molecular footprints reveal the impact of the protective HLA-A*03 allele in hepatitis C virus infection. Gut (2011) 1.01
Citrullination of proteins: a common post-translational modification pathway induced by different nanoparticles in vitro and in vivo. Nanomedicine (Lond) (2012) 1.00
Ursodeoxycholic acid inhibits interleukin 1 beta [corrected] and deoxycholic acid-induced activation of NF-kappaB and AP-1 in human colon cancer cells. Int J Cancer (2006) 0.99
The leukocyte protein L-plastin induces proliferation, invasion and loss of E-cadherin expression in colon cancer cells. Int J Cancer (2006) 0.98
Microdamage: a cell transducing mechanism based on ruptured osteocyte processes. J Biomech (2005) 0.98
The novel product of a five-exon stargazin-related gene abolishes Ca(V)2.2 calcium channel expression. EMBO J (2002) 0.98
Effectiveness and safety of tapentadol prolonged release for severe, chronic low back pain with or without a neuropathic pain component: results of an open-label, phase 3b study. Curr Med Res Opin (2012) 0.97
Regulation of Protein Kinase C function by phosphorylation on conserved and non-conserved sites. Cell Signal (2010) 0.97
Activation of stress-related signalling pathway in human cells upon SiO2 nanoparticles exposure as an early indicator of cytotoxicity. J Nanobiotechnology (2011) 0.97
Deoxycholate induces COX-2 expression via Erk1/2-, p38-MAPK and AP-1-dependent mechanisms in esophageal cancer cells. BMC Cancer (2009) 0.96
Constipation and pregnancy. Best Pract Res Clin Gastroenterol (2007) 0.96
Epithelial-mesenchymal transition (EMT) protein expression in a cohort of stage II colorectal cancer patients with characterized tumor budding and mismatch repair protein status. Int J Surg Pathol (2011) 0.95
Three-dimensional structure of CaV3.1: comparison with the cardiac L-type voltage-gated calcium channel monomer architecture. J Biol Chem (2009) 0.95
Rapid culture of Mycobacterium tuberculosis on blood agar in resource limited setting. Dan Med Bull (2009) 0.95
The ducky(2J) mutation in Cacna2d2 results in reduced spontaneous Purkinje cell activity and altered gene expression. J Neurosci (2006) 0.95
Engagement of CD44 modulates cyclooxygenase induction, VEGF generation, and proliferation in human vascular endothelial cells. FASEB J (2005) 0.95
Crystal structure of alkyl hydroperoxide-reductase (AhpC) from Helicobacter pylori. Biochim Biophys Acta (2005) 0.94
Low pH induces co-ordinate regulation of gene expression in oesophageal cells. Carcinogenesis (2005) 0.94
"Jelly dots": synthesis and cytotoxicity studies of CdTe quantum dot-gelatin nanocomposites. Small (2007) 0.94
Bile acid deoxycholate induces differential subcellular localisation of the PKC isoenzymes beta 1, epsilon and delta in colonic epithelial cells in a sodium butyrate insensitive manner. Int J Cancer (2005) 0.93
Stimulus-induced phosphorylation of PKC theta at the C-terminal hydrophobic-motif in human T lymphocytes. Biochem Biophys Res Commun (2005) 0.93
The stargazin-related protein gamma 7 interacts with the mRNA-binding protein heterogeneous nuclear ribonucleoprotein A2 and regulates the stability of specific mRNAs, including CaV2.2. J Neurosci (2008) 0.93
Bile acid toxicity structure-activity relationships: correlations between cell viability and lipophilicity in a panel of new and known bile acids using an oesophageal cell line (HET-1A). Bioorg Med Chem (2010) 0.93
Efficacy of Adalimumab as a long term maintenance therapy in ulcerative colitis. J Crohns Colitis (2012) 0.93
The value of pre-operative treatment with GnRH analogues in women with submucous fibroids: a double-blind, placebo-controlled randomized trial. Hum Reprod (2010) 0.92
Changes in hormone sensitivity in the ventral prostate of aging Sprague-Dawley rats. J Androl (2002) 0.92
CdTe nanoparticles display tropism to core histones and histone-rich cell organelles. Small (2008) 0.92
Hypoxia induces mitochondrial mutagenesis and dysfunction in inflammatory arthritis. Arthritis Rheum (2011) 0.92
Microscopic colitis: clinical characteristics, treatment and outcomes in an Irish population. Int J Colorectal Dis (2014) 0.91
COX-derived prostanoid pathways in gastrointestinal cancer development and progression: novel targets for prevention and intervention. Biochim Biophys Acta (2011) 0.91
Leukocyte function-associated antigen-1/intercellular adhesion molecule-1 interaction induces a novel genetic signature resulting in T-cells refractory to transforming growth factor-β signaling. J Biol Chem (2012) 0.91
Celiac disease--the villain unmasked? N Engl J Med (2003) 0.91
Myosin light chain kinase inhibition: correction of increased intestinal epithelial permeability in vitro. Pharm Res (2008) 0.90
Metastatic Melanoma presenting 24 years after surgical resection: a case report and review of the literature. Cases J (2009) 0.90
Detection and characterization of hemopoietic stem cells in the adult human small intestine. J Immunol (2006) 0.90
High clusterin expression correlates with a poor outcome in stage II colorectal cancers. Cancer Epidemiol Biomarkers Prev (2009) 0.90