Published in J Bacteriol on January 22, 2010
Copper stress affects iron homeostasis by destabilizing iron-sulfur cluster formation in Bacillus subtilis. J Bacteriol (2010) 1.40
Interplay between oxygen and Fe-S cluster biogenesis: insights from the Suf pathway. Biochemistry (2014) 0.92
Fe-S cluster biogenesis in Gram-positive bacteria: SufU is a zinc-dependent sulfur transfer protein. Biochemistry (2013) 0.87
Stress responses of the industrial workhorse Bacillus licheniformis to osmotic challenges. PLoS One (2013) 0.83
Aureolib - a proteome signature library: towards an understanding of staphylococcus aureus pathophysiology. PLoS One (2013) 0.83
The fungal α-aminoadipate pathway for lysine biosynthesis requires two enzymes of the aconitase family for the isomerization of homocitrate to homoisocitrate. Mol Microbiol (2012) 0.83
Nfu facilitates the maturation of iron-sulfur proteins and participates in virulence in Staphylococcus aureus. Mol Microbiol (2014) 0.83
Abbreviated Pathway for Biosynthesis of 2-Thiouridine in Bacillus subtilis. J Bacteriol (2015) 0.81
Recent advances in the Suf Fe-S cluster biogenesis pathway: Beyond the Proteobacteria. Biochim Biophys Acta (2014) 0.79
The unique regulation of iron-sulfur cluster biogenesis in a Gram-positive bacterium. Proc Natl Acad Sci U S A (2014) 0.78
Identification and characterization of a novel-type ferric siderophore reductase from a gram-positive extremophile. J Biol Chem (2010) 0.76
Physiological roles of bacillithiol in intracellular metal processing. Curr Genet (2015) 0.76
Crystal Structure of Bacillus subtilis Cysteine Desulfurase SufS and Its Dynamic Interaction with Frataxin and Scaffold Protein SufU. PLoS One (2016) 0.76
Genome sequence of the Thermotoga thermarum type strain (LA3(T)) from an African solfataric spring. Stand Genomic Sci (2014) 0.75
The RicAFT (YmcA-YlbF-YaaT) complex carries two [4Fe-4S](2+) clusters and may respond to redox changes. Mol Microbiol (2017) 0.75
Biological and Chemical Adaptation to Endogenous Hydrogen Peroxide Production in Streptococcus pneumoniae D39. mSphere (2017) 0.75
Protective role of bacillithiol in superoxide stress and Fe-S metabolism in Bacillus subtilis. Microbiologyopen (2015) 0.75
REQUIREMENTS FOR TRANSFORMATION IN BACILLUS SUBTILIS. J Bacteriol (1961) 41.67
PCR-synthesis of marker cassettes with long flanking homology regions for gene disruptions in S. cerevisiae. Yeast (1996) 8.45
Structure, function, and formation of biological iron-sulfur clusters. Annu Rev Biochem (2005) 6.82
Iron-sulfur clusters: nature's modular, multipurpose structures. Science (1997) 6.78
An efficient one-step site-directed and site-saturation mutagenesis protocol. Nucleic Acids Res (2004) 6.42
A DIRECT MICRODETERMINATION FOR SULFIDE. Anal Biochem (1965) 4.56
Function and biogenesis of iron-sulphur proteins. Nature (2009) 4.56
Maturation of iron-sulfur proteins in eukaryotes: mechanisms, connected processes, and diseases. Annu Rev Biochem (2008) 4.34
THE BIOSYNTHESIS OF LEUCINE. II. THE ENZYMIC ISOMERIZATION OF BETA-CARBOXY-BETA-HYDROXYISOCAPROATE AND ALPHA-HYDROXY-BETA-CARBOXYISOCAPROATE. Biochemistry (1964) 3.30
IscU as a scaffold for iron-sulfur cluster biosynthesis: sequential assembly of [2Fe-2S] and [4Fe-4S] clusters in IscU. Biochemistry (2000) 3.03
Temporal activation of beta-glucanase synthesis in Bacillus subtilis is mediated by the GTP pool. J Gen Microbiol (1993) 2.73
A third bacterial system for the assembly of iron-sulfur clusters with homologs in archaea and plastids. J Biol Chem (2002) 2.66
Genetic analysis in Bacillus subtilis. Methods Enzymol (1991) 2.56
Global analysis of the Bacillus subtilis Fur regulon and the iron starvation stimulon. Mol Microbiol (2002) 2.55
The Cfd1-Nbp35 complex acts as a scaffold for iron-sulfur protein assembly in the yeast cytosol. Nat Chem Biol (2007) 2.39
A xylose-inducible Bacillus subtilis integration vector and its application. Gene (1996) 2.36
Micromolar intracellular hydrogen peroxide disrupts metabolism by damaging iron-sulfur enzymes. J Biol Chem (2006) 2.34
The ABC transporter Atm1p is required for mitochondrial iron homeostasis. FEBS Lett (1997) 2.21
Analysis of genes involved in biosynthesis of the lantibiotic subtilin. Appl Environ Microbiol (1992) 2.08
NifS-directed assembly of a transient [2Fe-2S] cluster within the NifU protein. Proc Natl Acad Sci U S A (2000) 2.03
The SufE protein and the SufBCD complex enhance SufS cysteine desulfurase activity as part of a sulfur transfer pathway for Fe-S cluster assembly in Escherichia coli. J Biol Chem (2003) 1.97
Mechanism of aconitase action. I. The hydrogen transfer reaction. J Biol Chem (1967) 1.95
Genetic analysis of the isc operon in Escherichia coli involved in the biogenesis of cellular iron-sulfur proteins. J Biochem (2001) 1.95
The hydrogenase-like Nar1p is essential for maturation of cytosolic and nuclear iron-sulphur proteins. EMBO J (2004) 1.90
Fe-S cluster assembly pathways in bacteria. Microbiol Mol Biol Rev (2008) 1.88
SufE transfers sulfur from SufS to SufB for iron-sulfur cluster assembly. J Biol Chem (2007) 1.73
Bacterial cysteine desulfurases: their function and mechanisms. Appl Microbiol Biotechnol (2002) 1.73
In vivo iron-sulfur cluster formation. Proc Natl Acad Sci U S A (2008) 1.44
The asymmetric trimeric architecture of [2Fe-2S] IscU: implications for its scaffolding during iron-sulfur cluster biosynthesis. J Mol Biol (2008) 1.40
Preparation and properties of succinate: ubiquinone oxidoreductase (complex II). Methods Enzymol (1978) 1.40
NfuA, a new factor required for maturing Fe/S proteins in Escherichia coli under oxidative stress and iron starvation conditions. J Biol Chem (2008) 1.37
Mechanisms of iron-sulfur cluster assembly: the SUF machinery. J Biol Inorg Chem (2005) 1.32
A proposed role for the Azotobacter vinelandii NfuA protein as an intermediate iron-sulfur cluster carrier. J Biol Chem (2008) 1.27
Crystal structure of the molecular chaperone HscA substrate binding domain complexed with the IscU recognition peptide ELPPVKIHC. J Mol Biol (2004) 1.26
Interplay of IscA and IscU in biogenesis of iron-sulfur clusters. J Biol Chem (2006) 1.25
Identification of the Mycobacterium tuberculosis SUF machinery as the exclusive mycobacterial system of [Fe-S] cluster assembly: evidence for its implication in the pathogen's survival. J Bacteriol (2005) 1.23
Measuring nitric oxide and superoxide: rate constants for aconitase reactivity. Methods Enzymol (1996) 1.22
How Escherichia coli and Saccharomyces cerevisiae build Fe/S proteins. Adv Microb Physiol (2005) 1.21
Aconitases: a class of metalloproteins highly sensitive to nitric oxide synthesis. Methods Enzymol (1996) 1.19
Complementary roles of SufA and IscA in the biogenesis of iron-sulfur clusters in Escherichia coli. Biochem J (2008) 1.17
Native Escherichia coli SufA, coexpressed with SufBCDSE, purifies as a [2Fe-2S] protein and acts as an Fe-S transporter to Fe-S target enzymes. J Am Chem Soc (2009) 1.16
IscA/SufA paralogues are required for the [4Fe-4S] cluster assembly in enzymes of multiple physiological pathways in Escherichia coli under aerobic growth conditions. Biochem J (2009) 1.12
Contributions of the LPPVK motif of the iron-sulfur template protein IscU to interactions with the Hsc66-Hsc20 chaperone system. J Biol Chem (2003) 1.08
CpNifS-dependent iron-sulfur cluster biogenesis in chloroplasts. New Phytol (2006) 1.08
Preferential substrate binding orientation by the molecular chaperone HscA. J Biol Chem (2004) 1.05
The SUF iron-sulfur cluster biosynthetic machinery: sulfur transfer from the SUFS-SUFE complex to SUFA. FEBS Lett (2007) 1.05
The CsdA cysteine desulphurase promotes Fe/S biogenesis by recruiting Suf components and participates to a new sulphur transfer pathway by recruiting CsdL (ex-YgdL), a ubiquitin-modifying-like protein. Mol Microbiol (2009) 1.04
Structural studies of the Enterococcus faecalis SufU [Fe-S] cluster protein. BMC Biochem (2009) 0.93
Hydrodynamic characterization of the SufBC and SufCD complexes and their interaction with fluorescent adenosine nucleotides. Protein Sci (2008) 0.90
Iron-sulfur cluster proteins: electron transfer and beyond. Acta Biochim Pol (2006) 0.90
Iron-sulfur cluster biosynthesis: biochemical characterization of the conformational dynamics of Thermotoga maritima IscU and the relevance for cellular cluster assembly. J Biol Chem (2003) 0.89
Iron-sulfur cluster biosynthesis in photosynthetic organisms. Photosynth Res (2005) 0.85
Chemical rescue of a site-modified ligand to a [4Fe-4S] cluster in PsaC, a bacterial-like dicluster ferredoxin bound to Photosystem I. Biochim Biophys Acta (2007) 0.82
Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature. Nat Prod Rep (2013) 5.38
Siderophore-based iron acquisition and pathogen control. Microbiol Mol Biol Rev (2007) 4.87
Molecular mechanisms underlying nonribosomal peptide synthesis: approaches to new antibiotics. Chem Rev (2005) 4.64
Biosynthesis of nonribosomal peptides1. Annu Rev Microbiol (2004) 3.64
Components involved in assembly and dislocation of iron-sulfur clusters on the scaffold protein Isu1p. EMBO J (2003) 2.94
Nonribosomal peptides: from genes to products. Nat Prod Rep (2003) 2.73
Crystal structure of DhbE, an archetype for aryl acid activating domains of modular nonribosomal peptide synthetases. Proc Natl Acad Sci U S A (2002) 2.51
MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrity. Science (2012) 2.46
The Cfd1-Nbp35 complex acts as a scaffold for iron-sulfur protein assembly in the yeast cytosol. Nat Chem Biol (2007) 2.39
Activation of the iron regulon by the yeast Aft1/Aft2 transcription factors depends on mitochondrial but not cytosolic iron-sulfur protein biogenesis. J Biol Chem (2005) 2.33
The yeast frataxin homolog Yfh1p plays a specific role in the maturation of cellular Fe/S proteins. Hum Mol Genet (2002) 2.32
An interaction between frataxin and Isu1/Nfs1 that is crucial for Fe/S cluster synthesis on Isu1. EMBO Rep (2003) 2.29
Eukaryotic DNA polymerases require an iron-sulfur cluster for the formation of active complexes. Nat Chem Biol (2011) 2.20
Role of glutaredoxin-3 and glutaredoxin-4 in the iron regulation of the Aft1 transcriptional activator in Saccharomyces cerevisiae. J Biol Chem (2006) 2.18
The genome of Clostridium kluyveri, a strict anaerobe with unique metabolic features. Proc Natl Acad Sci U S A (2008) 2.12
The role of mitochondria in cellular iron-sulfur protein biogenesis and iron metabolism. Biochim Biophys Acta (2012) 2.09
Crystal structure of the termination module of a nonribosomal peptide synthetase. Science (2008) 2.02
Dissection of the mechanism for the stringent factor RelA. Mol Cell (2002) 1.98
Involvement of mitochondrial ferredoxin and para-aminobenzoic acid in yeast coenzyme Q biosynthesis. Chem Biol (2010) 1.93
Essential role of Isd11 in mitochondrial iron-sulfur cluster synthesis on Isu scaffold proteins. EMBO J (2005) 1.92
The hydrogenase-like Nar1p is essential for maturation of cytosolic and nuclear iron-sulphur proteins. EMBO J (2004) 1.90
Cytosolic monothiol glutaredoxins function in intracellular iron sensing and trafficking via their bound iron-sulfur cluster. Cell Metab (2010) 1.89
Biogenesis of cytosolic ribosomes requires the essential iron-sulphur protein Rli1p and mitochondria. EMBO J (2005) 1.87
Ways of assembling complex natural products on modular nonribosomal peptide synthetases. Chembiochem (2002) 1.85
Localization and functionality of microsporidian iron-sulphur cluster assembly proteins. Nature (2008) 1.84
Nonribosomal peptide synthetases: structures and dynamics. Curr Opin Struct Biol (2010) 1.83
Mechanistic and structural basis of stereospecific Cbeta-hydroxylation in calcium-dependent antibiotic, a daptomycin-type lipopeptide. ACS Chem Biol (2007) 1.77
Maturation of cytosolic iron-sulfur proteins requires glutathione. J Biol Chem (2002) 1.76
Insights into the biosynthesis and stability of the lasso peptide capistruin. Chem Biol (2009) 1.75
A specific role of the yeast mitochondrial carriers MRS3/4p in mitochondrial iron acquisition under iron-limiting conditions. J Biol Chem (2003) 1.74
Functional dissection of surfactin synthetase initiation module reveals insights into the mechanism of lipoinitiation. Chem Biol (2010) 1.72
An allylic ketyl radical intermediate in clostridial amino-acid fermentation. Nature (2008) 1.67
Iron-sulfur protein maturation in human cells: evidence for a function of frataxin. Hum Mol Genet (2004) 1.66
Structural basis for the selectivity of the external thioesterase of the surfactin synthetase. Nature (2008) 1.66
Regeneration of misprimed nonribosomal peptide synthetases by type II thioesterases. Proc Natl Acad Sci U S A (2002) 1.64
The eukaryotic P loop NTPase Nbp35: an essential component of the cytosolic and nuclear iron-sulfur protein assembly machinery. Proc Natl Acad Sci U S A (2005) 1.64
Inhibition of aryl acid adenylation domains involved in bacterial siderophore synthesis. FEBS J (2006) 1.61
Conformational switches modulate protein interactions in peptide antibiotic synthetases. Science (2006) 1.61
Mitochondrial Iba57p is required for Fe/S cluster formation on aconitase and activation of radical SAM enzymes. Mol Cell Biol (2007) 1.59
A fatal mitochondrial disease is associated with defective NFU1 function in the maturation of a subset of mitochondrial Fe-S proteins. Am J Hum Genet (2011) 1.57
Tah18 transfers electrons to Dre2 in cytosolic iron-sulfur protein biogenesis. Nat Chem Biol (2010) 1.54
Role of human mitochondrial Nfs1 in cytosolic iron-sulfur protein biogenesis and iron regulation. Mol Cell Biol (2006) 1.54
Functional characterization of the eukaryotic cysteine desulfurase Nfs1p from Saccharomyces cerevisiae. J Biol Chem (2004) 1.51
Crystal structure of DltA. Implications for the reaction mechanism of non-ribosomal peptide synthetase adenylation domains. J Biol Chem (2008) 1.50
Mechanisms of iron-sulfur protein maturation in mitochondria, cytosol and nucleus of eukaryotes. Biochim Biophys Acta (2006) 1.50
Evidence for a monomeric structure of nonribosomal Peptide synthetases. Chem Biol (2002) 1.49
Structural basis for the cyclization of the lipopeptide antibiotic surfactin by the thioesterase domain SrfTE. Structure (2002) 1.49
Iron-sulfur proteins in health and disease. Trends Endocrinol Metab (2010) 1.49
Isolation and structural characterization of capistruin, a lasso peptide predicted from the genome sequence of Burkholderia thailandensis E264. J Am Chem Soc (2008) 1.47
Human ind1, an iron-sulfur cluster assembly factor for respiratory complex I. Mol Cell Biol (2009) 1.46
Characterization of iron-sulfur protein assembly in isolated mitochondria. A requirement for ATP, NADH, and reduced iron. J Biol Chem (2002) 1.44
The iron-sulphur protein Ind1 is required for effective complex I assembly. EMBO J (2008) 1.42
Chemoenzymatic and template-directed synthesis of bioactive macrocyclic peptides. Microbiol Mol Biol Rev (2006) 1.41
The yeast scaffold proteins Isu1p and Isu2p are required inside mitochondria for maturation of cytosolic Fe/S proteins. Mol Cell Biol (2004) 1.41
Copper stress affects iron homeostasis by destabilizing iron-sulfur cluster formation in Bacillus subtilis. J Bacteriol (2010) 1.40
Structural and functional insights into a peptide bond-forming bidomain from a nonribosomal peptide synthetase. Structure (2007) 1.40
Humans possess two mitochondrial ferredoxins, Fdx1 and Fdx2, with distinct roles in steroidogenesis, heme, and Fe/S cluster biosynthesis. Proc Natl Acad Sci U S A (2010) 1.40
New glycyl radical enzymes catalysing key metabolic steps in anaerobic bacteria. Biol Chem (2005) 1.40
The radical SAM enzyme AlbA catalyzes thioether bond formation in subtilosin A. Nat Chem Biol (2012) 1.39
The essential WD40 protein Cia1 is involved in a late step of cytosolic and nuclear iron-sulfur protein assembly. Mol Cell Biol (2005) 1.39
Cellular and mitochondrial remodeling upon defects in iron-sulfur protein biogenesis. J Biol Chem (2008) 1.39
Macrocyclization strategies in polyketide and nonribosomal peptide biosynthesis. Nat Prod Rep (2007) 1.38
Bacterial cold shock responses. Sci Prog (2003) 1.37
Ebony, a novel nonribosomal peptide synthetase for beta-alanine conjugation with biogenic amines in Drosophila. J Biol Chem (2003) 1.36
Sodium ion pumps and hydrogen production in glutamate fermenting anaerobic bacteria. J Mol Microbiol Biotechnol (2005) 1.35
The effects of mitochondrial iron homeostasis on cofactor specificity of superoxide dismutase 2. EMBO J (2006) 1.34
Human Nbp35 is essential for both cytosolic iron-sulfur protein assembly and iron homeostasis. Mol Cell Biol (2008) 1.34
EPR and Mössbauer spectroscopy of intact mitochondria isolated from Yah1p-depleted Saccharomyces cerevisiae. Biochemistry (2008) 1.33
Identification of a gene cluster for biosynthesis of mannosylerythritol lipids in the basidiomycetous fungus Ustilago maydis. Appl Environ Microbiol (2006) 1.33
Exploitation of the selectivity-conferring code of nonribosomal peptide synthetases for the rational design of novel peptide antibiotics. Biochemistry (2002) 1.33
Genomewide transcriptional analysis of the cold shock response in Bacillus subtilis. J Bacteriol (2002) 1.32
Cloning and characterization of the biosynthetic gene cluster for kutznerides. Proc Natl Acad Sci U S A (2007) 1.31
Cold-induced putative DEAD box RNA helicases CshA and CshB are essential for cold adaptation and interact with cold shock protein B in Bacillus subtilis. J Bacteriol (2006) 1.30
Osmotically induced synthesis of the compatible solute hydroxyectoine is mediated by an evolutionarily conserved ectoine hydroxylase. J Biol Chem (2007) 1.28
Synthesis and uptake of the compatible solutes ectoine and 5-hydroxyectoine by Streptomyces coelicolor A3(2) in response to salt and heat stresses. Appl Environ Microbiol (2008) 1.27
Specialized function of yeast Isa1 and Isa2 proteins in the maturation of mitochondrial [4Fe-4S] proteins. J Biol Chem (2011) 1.26
Iron-dependent degradation of apo-IRP1 by the ubiquitin-proteasome pathway. Mol Cell Biol (2007) 1.25
Analysis of iron-sulfur protein maturation in eukaryotes. Nat Protoc (2009) 1.25
Coenzyme Q biosynthesis: Coq6 is required for the C5-hydroxylation reaction and substrate analogs rescue Coq6 deficiency. Chem Biol (2011) 1.23
Acryloyl-CoA reductase from Clostridium propionicum. An enzyme complex of propionyl-CoA dehydrogenase and electron-transferring flavoprotein. Eur J Biochem (2003) 1.21