1
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Transition-metal-catalyzed direct arylation of (hetero)arenes by C-H bond cleavage.
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Angew Chem Int Ed Engl
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2009
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2.29
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2
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The asthma-associated ORMDL3 gene product regulates endoplasmic reticulum-mediated calcium signaling and cellular stress.
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Hum Mol Genet
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2010
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1.83
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3
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A loss-of-function nonsynonymous polymorphism in the osmoregulatory TRPV4 gene is associated with human hyponatremia.
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Proc Natl Acad Sci U S A
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2009
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1.25
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4
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Potassium channels: new targets in cancer therapy.
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Cancer Detect Prev
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2006
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1.18
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5
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Kv1.3/Kv1.5 heteromeric channels compromise pharmacological responses in macrophages.
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Biochem Biophys Res Commun
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2006
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1.08
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6
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Disruption of erythroid K-Cl cotransporters alters erythrocyte volume and partially rescues erythrocyte dehydration in SAD mice.
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J Clin Invest
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2007
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1.05
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7
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Phosphatidylinositol-4,5-biphosphate-dependent rearrangement of TRPV4 cytosolic tails enables channel activation by physiological stimuli.
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Proc Natl Acad Sci U S A
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2013
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0.99
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8
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Copper-catalyzed "click" reaction/direct arylation sequence: modular syntheses of 1,2,3-triazoles.
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Org Lett
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2008
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0.99
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9
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KCNQ1/KCNE1 channels during germ-cell differentiation in the rat: expression associated with testis pathologies.
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J Cell Physiol
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2005
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0.96
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10
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IP3 receptor binds to and sensitizes TRPV4 channel to osmotic stimuli via a calmodulin-binding site.
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J Biol Chem
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2008
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0.96
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11
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The TRPV4 channel.
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Handb Exp Pharmacol
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2014
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0.94
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12
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Cu(I)-catalyzed regioselective synthesis of polysubstituted furans from propargylic esters via postulated (2-furyl)carbene complexes.
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J Am Chem Soc
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2008
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0.94
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13
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ORMDL3 modulates store-operated calcium entry and lymphocyte activation.
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Hum Mol Genet
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2012
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0.93
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14
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Rearrangement of propargylic esters: metal-based stereospecific synthesis of (E)- and (Z)-knoevenagel derivatives.
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J Am Chem Soc
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2007
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0.91
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15
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Ruthenium-catalyzed regioselective direct alkylation of arenes with unactivated alkyl halides through C-H bond cleavage.
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Angew Chem Int Ed Engl
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2009
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0.90
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16
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Immunomodulation of voltage-dependent K+ channels in macrophages: molecular and biophysical consequences.
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J Gen Physiol
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2010
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0.89
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17
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Protein kinase C (PKC) activity regulates functional effects of Kvβ1.3 subunit on KV1.5 channels: identification of a cardiac Kv1.5 channelosome.
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J Biol Chem
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2012
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0.86
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18
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Assisted ruthenium-catalyzed C-H bond activation: carboxylic acids as cocatalysts for generally applicable direct arylations in apolar solvents.
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Org Lett
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2008
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0.84
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19
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Ruthenium-catalyzed direct arylations of N-aryl 1,2,3-triazoles with aryl chlorides as electrophiles.
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ChemSusChem
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2009
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0.84
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20
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Multiple Kv1.5 targeting to membrane surface microdomains.
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J Cell Physiol
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2008
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0.83
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21
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Voltage-dependent K+ channel beta subunits in muscle: differential regulation during postnatal development and myogenesis.
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J Cell Physiol
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2003
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0.82
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22
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Ion channels in asthma.
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J Biol Chem
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2011
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0.82
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23
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Metal-free direct arylations of indoles and pyrroles with diaryliodonium salts.
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Org Lett
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2011
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0.82
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24
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Gold-catalyzed synthesis of tetrahydrocarbazole derivatives through an intermolecular cycloaddition of vinyl indoles and N-allenamides.
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Chem Commun (Camb)
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2013
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0.81
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25
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Air-stable secondary phosphine oxide as preligand for palladium-catalyzed intramolecular alpha-arylations with chloroarenes.
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Org Lett
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2009
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0.80
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26
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Mechanistic insight into direct arylations with ruthenium(II) carboxylate catalysts.
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Org Lett
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2010
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0.80
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27
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Carboxylate-assisted ruthenium-catalyzed direct alkylations of ketimines.
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Org Lett
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2011
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0.80
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28
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Catalytic direct arylations in polyethylene glycol (PEG): recyclable palladium(0) catalyst for C-H bond cleavages in the presence of air.
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Org Lett
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2009
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0.79
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29
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Highly chemo-, regio-, and stereoselective [3+2]-cyclization of activated and deactivated allenes with alkenyl Fischer carbene complexes: a straightforward access to alkylidenecyclopentanone derivatives.
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J Am Chem Soc
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2006
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0.78
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30
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Gold-catalyzed functionalization of unactivated C(sp3)-H bonds by hydride transfer facilitated by alkynylspirocyclopropanes.
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Angew Chem Int Ed Engl
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2012
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0.78
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31
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Impaired voltage-gated K+ channel expression in brain during experimental cancer cachexia.
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FEBS Lett
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2003
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0.77
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32
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Base- and metal-free C-H direct arylations of naphthalene and other unbiased arenes with diaryliodonium salts.
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Chem Commun (Camb)
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2012
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0.77
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33
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Metal-controlled selective [3+2] cyclization reactions of alkenyl Fischer carbene complexes and allenes.
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J Am Chem Soc
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2004
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0.77
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34
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New Fischer carbene complexes of rhodium(i): preparation and 2-cyclopentenone ring synthesis by annelation to alkynes.
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J Am Chem Soc
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2004
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0.77
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35
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Mechanistic studies on the rearrangement of 1-alkenyl-2-alkynylcyclopropanes: from allylic gold(I) cations to stable carbocations.
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Angew Chem Int Ed Engl
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2014
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0.77
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36
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Zinc-catalyzed synthesis of functionalized furans and triarylmethanes from enynones and alcohols or azoles: dual X-H bond activation by zinc.
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Angew Chem Int Ed Engl
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2013
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0.76
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37
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Ruthenium-catalyzed direct arylations through C-H bond cleavages.
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Top Curr Chem
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2010
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0.76
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38
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Gold-catalyzed rearrangements: reaction pathways using 1-alkenyl-2-alkynylcyclopropane substrates.
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Angew Chem Int Ed Engl
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2011
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0.76
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39
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Specific synthesis of 1,2- and 1,3-dialkylidenecycloheptanes by [3+2+2] cyclization of alkenyl Fischer carbene complexes and allenes.
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J Am Chem Soc
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2004
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0.76
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40
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Zinc-catalyzed synthesis of 2-alkenylfurans via cross-coupling of enynones and diazo compounds.
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Chem Commun (Camb)
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2014
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0.75
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41
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Alkynylcyclopropanes from terminal alkynes through consecutive coupling to Fischer carbene complexes and selective propargylene transfer.
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Chemistry
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2011
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0.75
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42
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Zinc-catalyzed cyclopropenation of alkynes via 2-furylcarbenoids.
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Org Lett
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2014
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0.75
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43
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Transmetalation reactions from Fischer carbene complexes to late transition metals: a DFT study.
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Chemistry
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2008
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0.75
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44
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Rhodium-catalyzed carbene transfer to alkynes via 2-furylcarbenes generated from enynones.
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Chem Commun (Camb)
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2013
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0.75
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