PubRank

Sherry Niessen

Author PubWeight™ 82.14‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Monoacylglycerol lipase regulates a fatty acid network that promotes cancer pathogenesis. Cell 2010 5.47
2 A conserved protein network controls assembly of the outer kinetochore and its ability to sustain tension. Genes Dev 2004 5.23
3 The CREB coactivator TORC2 functions as a calcium- and cAMP-sensitive coincidence detector. Cell 2004 4.91
4 TRB3 links the E3 ubiquitin ligase COP1 to lipid metabolism. Science 2006 3.26
5 A streamlined platform for high-content functional proteomics of primary human specimens. Nat Methods 2005 3.00
6 An enzyme that regulates ether lipid signaling pathways in cancer annotated by multidimensional profiling. Chem Biol 2006 2.98
7 A high-resolution C. elegans essential gene network based on phenotypic profiling of a complex tissue. Cell 2011 2.64
8 A hormone-dependent module regulating energy balance. Cell 2011 2.30
9 Proteomic profiling of metalloprotease activities with cocktails of active-site probes. Nat Chem Biol 2006 2.25
10 Superfamily-wide portrait of serine hydrolase inhibition achieved by library-versus-library screening. Proc Natl Acad Sci U S A 2010 2.16
11 Polo-like kinase 4 kinase activity limits centrosome overduplication by autoregulating its own stability. J Cell Biol 2010 2.05
12 Carcinoma and stromal enzyme activity profiles associated with breast tumor growth in vivo. Proc Natl Acad Sci U S A 2004 1.96
13 Mps1 phosphorylation of Dam1 couples kinetochores to microtubule plus ends at metaphase. Curr Biol 2006 1.83
14 Highly selective inhibitors of monoacylglycerol lipase bearing a reactive group that is bioisosteric with endocannabinoid substrates. Chem Biol 2012 1.79
15 Monoacylglycerol lipase exerts dual control over endocannabinoid and fatty acid pathways to support prostate cancer. Chem Biol 2011 1.74
16 Click-generated triazole ureas as ultrapotent in vivo-active serine hydrolase inhibitors. Nat Chem Biol 2011 1.66
17 Selectivity of inhibitors of endocannabinoid biosynthesis evaluated by activity-based protein profiling. Bioorg Med Chem Lett 2008 1.54
18 The yeast lgl family member Sro7p is an effector of the secretory Rab GTPase Sec4p. J Cell Biol 2006 1.54
19 Genomic insights into the physiology and ecology of the marine filamentous cyanobacterium Lyngbya majuscula. Proc Natl Acad Sci U S A 2011 1.40
20 Regulation of tumor necrosis factor receptor-1 and the IKK-NF-kappaB pathway by LDL receptor-related protein explains the antiinflammatory activity of this receptor. Blood 2008 1.25
21 Forward chemical genetic approach identifies new role for GAPDH in insulin signaling. Nat Chem Biol 2006 1.19
22 Direct binding of SAS-6 to ZYG-1 recruits SAS-6 to the mother centriole for cartwheel assembly. Dev Cell 2013 1.13
23 Activity-based protein profiling implicates urokinase activation as a key step in human fibrosarcoma intravasation. J Biol Chem 2006 1.12
24 An orthogonal active site identification system (OASIS) for proteomic profiling of natural product biosynthesis. ACS Chem Biol 2009 1.11
25 RBBP9: a tumor-associated serine hydrolase activity required for pancreatic neoplasia. Proc Natl Acad Sci U S A 2009 1.11
26 The intramembrane protease Sppl2a is required for B cell and DC development and survival via cleavage of the invariant chain. J Exp Med 2012 1.07
27 Diversity of serine hydrolase activities of unchallenged and botrytis-infected Arabidopsis thaliana. Mol Cell Proteomics 2009 1.05
28 Phosphorylation of the chromosomal passenger protein Bir1 is required for localization of Ndc10 to the spindle during anaphase and full spindle elongation. Mol Biol Cell 2005 1.03
29 Metabolomics annotates ABHD3 as a physiologic regulator of medium-chain phospholipids. Nat Chem Biol 2011 1.02
30 Type I signal peptidase and protein secretion in Staphylococcus aureus. J Bacteriol 2012 1.01
31 Subclassification and biochemical analysis of plant papain-like cysteine proteases displays subfamily-specific characteristics. Plant Physiol 2012 0.99
32 PRMT5 modulates the metabolic response to fasting signals. Proc Natl Acad Sci U S A 2013 0.98
33 IGF1-R signals through the RON receptor to mediate pancreatic cancer cell migration. Carcinogenesis 2011 0.96
34 The RON-receptor regulates pancreatic cancer cell migration through phosphorylation-dependent breakdown of the hemidesmosome. Int J Cancer 2012 0.94
35 Hsp70/Hsp90 chaperone machinery is involved in the assembly of the purinosome. Proc Natl Acad Sci U S A 2013 0.94
36 Dim1p is required for efficient splicing and export of mRNA encoding lid1p, a component of the fission yeast anaphase-promoting complex. Eukaryot Cell 2005 0.93
37 Pseudomonas syringae pv. syringae uses proteasome inhibitor syringolin A to colonize from wound infection sites. PLoS Pathog 2013 0.92
38 Proteasome activity imaging and profiling characterizes bacterial effector syringolin A. Plant Physiol 2010 0.90
39 The zipcode-binding protein ZBP1 influences the subcellular location of the Ro 60-kDa autoantigen and the noncoding Y3 RNA. RNA 2011 0.88
40 The proteome of mouse brain microvessel membranes and basal lamina. J Cereb Blood Flow Metab 2011 0.87
41 Selective inhibitor of platelet-activating factor acetylhydrolases 1b2 and 1b3 that impairs cancer cell survival. ACS Chem Biol 2015 0.87
42 Competitive activity-based protein profiling identifies aza-β-lactams as a versatile chemotype for serine hydrolase inhibition. J Am Chem Soc 2012 0.86
43 Affinity purification of protein complexes in C. elegans. Methods Cell Biol 2011 0.84
44 LDL receptor-related protein 1 regulates the abundance of diverse cell-signaling proteins in the plasma membrane proteome. J Proteome Res 2010 0.84
45 Practical 4'-phosphopantetheine active site discovery from proteomic samples. J Proteome Res 2010 0.83
46 Breast cancer cell lines grown in vivo: what goes in isn't always the same as what comes out. Cell Cycle 2005 0.82
47 Identification of a selective, activity-based probe for glyceraldehyde 3-phosphate dehydrogenases. Angew Chem Int Ed Engl 2012 0.80
48 Resin-based investigation of acyl carrier protein interaction networks in Escherichia coli. Bioorg Med Chem 2011 0.78
49 HPLC separation of digested proteins and preparation for matrix-assisted laser desorption/ionization analysis. CSH Protoc 2006 0.78
50 Chemoproteomic discovery of AADACL1 as a regulator of human platelet activation. Chem Biol 2013 0.77
51 A chemical biology approach to interrogate quorum-sensing regulated behaviors at the molecular and cellular level. Chem Biol 2013 0.77
52 Silver Staining, Digestion, and Extraction of Peptides from an Acrylamide Gel for MS Analysis. CSH Protoc 2006 0.76
53 Activity-based probes for monitoring postproline protease activity. Chembiochem 2009 0.75
54 Direct Enzymatic Digestion of Protein Complexes for MS Analysis. CSH Protoc 2006 0.75
55 Overview of affinity purification in combination with mass spectrometry. CSH Protoc 2006 0.75
56 Discovery of N-((3R,4R)-4-Fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)-9-methyl-9H-purin-2-yl)pyrrolidine-3-yl)acrylamide (PF-06747775) through Structure-Based Drug Design: A High Affinity Irreversible Inhibitor Targeting Oncogenic EGFR Mutants with Selectivity over Wild-Type EGFR. J Med Chem 2017 0.75