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1
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Simultaneous detection of 15 human cytokines in a single sample of stimulated peripheral blood mononuclear cells.
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Clin Diagn Lab Immunol
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2003
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3.70
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2
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Regulation of Treg functionality by acetylation-mediated Foxp3 protein stabilization.
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Blood
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2009
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2.49
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3
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Prerequisites for cytokine measurements in clinical trials with multiplex immunoassays.
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BMC Immunol
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2009
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2.27
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4
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Improved multiplex immunoassay performance in human plasma and synovial fluid following removal of interfering heterophilic antibodies.
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J Immunol Methods
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2005
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2.09
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5
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Stabilization of the transcription factor Foxp3 by the deubiquitinase USP7 increases Treg-cell-suppressive capacity.
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Immunity
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2013
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2.05
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6
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Blood and synovial fluid cytokine signatures in patients with juvenile idiopathic arthritis: a cross-sectional study.
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Ann Rheum Dis
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2006
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1.95
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7
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Tolerogenic immune responses to novel T-cell epitopes from heat-shock protein 60 in juvenile idiopathic arthritis.
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Lancet
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2005
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1.93
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8
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Histone deacetylase inhibitors suppress inflammatory activation of rheumatoid arthritis patient synovial macrophages and tissue.
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J Immunol
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2010
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1.44
|
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9
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Mutations in the perforin gene can be linked to macrophage activation syndrome in patients with systemic onset juvenile idiopathic arthritis.
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Rheumatology (Oxford)
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2009
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1.26
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10
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Functional human regulatory T cells fail to control autoimmune inflammation due to PKB/c-akt hyperactivation in effector cells.
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Blood
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2011
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1.24
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11
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T cells out of control--impaired immune regulation in the inflamed joint.
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Nat Rev Rheumatol
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2013
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1.14
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12
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Canonical Wnt signaling negatively modulates regulatory T cell function.
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Immunity
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2013
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1.13
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13
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Expression of the inflammatory chemokines CCL5, CCL3 and CXCL10 in juvenile idiopathic arthritis, and demonstration of CCL5 production by an atypical subset of CD8+ T cells.
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Arthritis Res Ther
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2006
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1.10
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14
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Cytokine assays: an assessment of the preparation and treatment of blood and tissue samples.
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Methods
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2013
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1.09
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15
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Effectiveness of first-line treatment with recombinant interleukin-1 receptor antagonist in steroid-naive patients with new-onset systemic juvenile idiopathic arthritis: results of a prospective cohort study.
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Arthritis Rheumatol
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2014
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1.04
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16
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Immunostimulatory DNA sequences influence the course of adjuvant arthritis.
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J Immunol
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2002
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1.03
|
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17
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Differential cytokine profiles in juvenile idiopathic arthritis subtypes revealed by cluster analysis.
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Rheumatology (Oxford)
|
2009
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1.00
|
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18
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Human regulatory T cell suppressive function is independent of apoptosis induction in activated effector T cells.
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PLoS One
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2009
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0.94
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|
19
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Hsp60 in inflamed muscle tissue is the target of regulatory autoreactive T cells in patients with juvenile dermatomyositis.
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Arthritis Rheum
|
2008
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0.94
|
|
20
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Defective phosphorylation of interleukin-18 receptor beta causes impaired natural killer cell function in systemic-onset juvenile idiopathic arthritis.
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Arthritis Rheum
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2009
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0.92
|
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21
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Case report: severe central nervous system involvement in juvenile dermatomyositis.
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J Rheumatol
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2003
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0.92
|
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22
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STAT3 regulates monocyte TNF-alpha production in systemic inflammation caused by cardiac surgery with cardiopulmonary bypass.
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PLoS One
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2012
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0.91
|
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23
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A multiplex immunoassay for human adipokine profiling.
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Clin Chem
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2010
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0.91
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|
24
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Hsp70 and cardiac surgery: molecular chaperone and inflammatory regulator with compartmentalized effects.
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Cell Stress Chaperones
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2008
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0.90
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25
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CCL3 (MIP-1 alpha) levels are elevated during acute coronary syndromes and show strong prognostic power for future ischemic events.
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J Mol Cell Cardiol
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2008
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0.89
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26
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Hydroxychloroquine preferentially induces apoptosis of CD45RO+ effector T cells by inhibiting autophagy: a possible mechanism for therapeutic modulation of T cells.
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J Allergy Clin Immunol
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2013
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0.89
|
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27
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Recognition of self-heat shock protein 60 by T cells from patients with atopic dermatitis.
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Cell Stress Chaperones
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2012
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0.87
|
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28
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Modulation of T cell function by combination of epitope specific and low dose anticytokine therapy controls autoimmune arthritis.
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PLoS One
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2006
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0.85
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29
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Neonatal thymectomy reveals differentiation and plasticity within human naive T cells.
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J Clin Invest
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2016
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0.85
|
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30
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Heat-shock protein 60 as a tool for novel therapeutic strategies that target the induction of regulatory T cells in human arthritis.
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Expert Opin Biol Ther
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2006
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0.84
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31
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An urge for change: transitional care for young adults with juvenile idiopathic arthritis.
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Patient Educ Couns
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2013
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0.84
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32
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Safety and efficacy of meningococcal c vaccination in juvenile idiopathic arthritis.
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Arthritis Rheum
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2007
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0.84
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33
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Cerebral ischemia initiates an immediate innate immune response in neonates during cardiac surgery.
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J Neuroinflammation
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2013
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0.83
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34
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FOXP3+ CD4+ Tregs lose suppressive potential but remain anergic during transient inflammation in human.
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Eur J Immunol
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2011
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0.83
|
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35
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Pan-DR-binding Hsp60 self epitopes induce an interleukin-10-mediated immune response in rheumatoid arthritis.
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Arthritis Rheum
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2009
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0.82
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36
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Defective TH17 development in human neonatal T cells involves reduced RORC2 mRNA content.
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J Allergy Clin Immunol
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2013
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0.82
|
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37
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HSP: Bystander Antigen in Atopic Diseases?
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Front Immunol
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2012
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0.81
|
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38
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Changing winds in refractory autoimmune disease in children: clearing the road for tolerance with cellular therapies.
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Curr Opin Rheumatol
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2012
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0.81
|
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39
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Gut derived lactic acid bacteria induce strain specific CD4(+) T cell responses in human PBMC.
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Clin Nutr
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2011
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0.81
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40
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Cord blood CD4+ T cells respond to self heat shock protein 60 (HSP60).
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PLoS One
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2011
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0.81
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41
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Survival, but not maturation, is affected in neutrophil progenitors from GSD-1b patients.
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J Inherit Metab Dis
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2011
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0.80
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42
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The effect of autoimmune arthritis treatment strategies on regulatory T-cell dynamics.
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Curr Opin Rheumatol
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2013
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0.80
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43
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Novel self-epitopes derived from aggrecan, fibrillin, and matrix metalloproteinase-3 drive distinct autoreactive T-cell responses in juvenile idiopathic arthritis and in health.
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Arthritis Res Ther
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2006
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0.79
|
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44
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Anti-tumor necrosis factor α targets protein kinase B/c-Akt-induced resistance of effector cells to suppression in juvenile idiopathic arthritis.
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Arthritis Rheum
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2013
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0.78
|
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45
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TLR9 agonist CpG enhances protective nasal HSP60 peptide vaccine efficacy in experimental autoimmune arthritis.
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Ann Rheum Dis
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2012
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0.78
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46
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Novel pan-DR-binding T cell epitopes of adenovirus induce pro-inflammatory cytokines and chemokines in healthy donors.
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Int Immunol
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2006
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0.78
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47
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Selection of perforin expressing CD4+ adenovirus-specific T-cells with artificial antigen presenting cells.
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Clin Immunol
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2013
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0.78
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48
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Critical role for programmed death 1 signaling and protein kinase B in augmented regulatory T-cell induction in cord blood.
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J Allergy Clin Immunol
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2011
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0.78
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49
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Bystander suppression of experimental arthritis by nasal administration of a heat shock protein peptide.
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Ann Rheum Dis
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2011
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0.78
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50
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Stem cell transplantation for autoimmune disorders. Refractory juvenile idiopathic arthritis.
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Best Pract Res Clin Haematol
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2004
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0.77
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51
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Heat shock protein 60 reactive T cells in juvenile idiopathic arthritis: what is new?
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Arthritis Res Ther
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2009
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0.77
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52
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Treating arthritis by immunomodulation: is there a role for regulatory T cells?
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Rheumatology (Oxford)
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2010
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0.77
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53
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Vaccination leads to an aberrant FOXP3 T-cell response in non-remitting juvenile idiopathic arthritis.
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Ann Rheum Dis
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2011
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0.77
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54
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Plasma IL-25 is elevated in a subgroup of patients with clinical reactivity to peanut.
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Clin Transl Allergy
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2013
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0.77
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55
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Decreased levels of sCD21 and sCD23 in blood of patients with systemic-juvenile arthritis, polyarticular-juvenile arthritis, and pauciarticular-juvenile arthritis.
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Rheumatol Int
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2011
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0.77
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56
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Increased immune reactivity towards human hsp60 in patients with primary Sjögren's syndrome is associated with increased cytokine levels and glandular inflammation.
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Clin Exp Rheumatol
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2012
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0.76
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57
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Different cytokine signatures in children with localized and invasive adenovirus infection after stem cell transplantation.
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Pediatr Transplant
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2010
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0.76
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58
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Brief report: Autologous stem cell transplantation restores immune tolerance in experimental arthritis by renewal and modulation of the Teff cell compartment.
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Arthritis Rheumatol
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2014
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0.75
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59
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T cell recognition of naturally presented epitopes of self-heat shock protein 70.
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Cell Stress Chaperones
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2014
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0.75
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60
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Plasma chemokines in early wheezers predict the development of allergic asthma.
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Am J Respir Crit Care Med
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2013
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0.75
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