Published in Science on December 02, 1977
Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach? Nat Rev Drug Discov (2009) 10.32
Paramagnetic changes in cancer: DMBA-induced tumours studied in non-lyophilized and lyophilized tissues. Br J Cancer (1979) 0.96
Paramagnetic changes in cancer: growth of Walker 256 carcinoma studied in frozen and lyophilized tissues. Br J Cancer (1979) 0.88
The nature of the ESR signal in lyophilized tissue and its relevance to malignancy. Br J Cancer (1984) 0.81
ESR signals of lyophilized tissue. Br J Cancer (1980) 0.78
Lithium phthalocyanine: a probe for electron paramagnetic resonance oximetry in viable biological systems. Proc Natl Acad Sci U S A (1993) 2.50
Protocol for emergency EPR dosimetry in fingernails. Radiat Meas (2007) 2.41
EPR dosimetry in chemically treated fingernails. Radiat Meas (2007) 2.33
A standardized test for the identification and characterization of melanins using electron paramagnetic resonance (EPR) spectroscopy. Pigment Cell Res (1993) 1.80
Applications of magnetic resonance in model systems: cancer therapeutics. Neoplasia (2000) 1.72
Stimulation of reactive oxygen, but not reactive nitrogen species, in vascular endothelial cells exposed to low levels of arsenite. Free Radic Biol Med (1999) 1.72
Electron paramagnetic resonance in human fingernails: the sponge model implication. Radiat Environ Biophys (2008) 1.55
In vivo dosimetry by electron spin resonance spectroscopy. Health Phys (1968) 1.43
Studies on human uterine cervix and rat uterus using S-, X- and Q-band electron-spin-resonance spectroscopy. Biochem J (1984) 1.38
Development and evaluation of biocompatible films of polytetrafluoroethylene polymers holding lithium phthalocyanine crystals for their use in EPR oximetry. Biosens Bioelectron (2005) 1.30
The effects of ketamine-xylazine anesthesia on cerebral blood flow and oxygenation observed using nuclear magnetic resonance perfusion imaging and electron paramagnetic resonance oximetry. Brain Res (2001) 1.29
Simultaneous multi-site EPR spectroscopy in vivo. Magn Reson Med (1993) 1.28
Electronically tunable surface-coil-type resonator for L-band EPR spectroscopy. J Magn Reson (2000) 1.26
Radiation dose reconstruction from L-band in vivo EPR spectroscopy of intact teeth: Comparison of methods. Radiat Meas (2007) 1.25
Binding of iron to neuromelanin of human substantia nigra and synthetic melanin: an electron paramagnetic resonance spectroscopy study. Free Radic Biol Med (1997) 1.23
Rickettsia rickettsii induces superoxide radical and superoxide dismutase in human endothelial cells. Infect Immun (1992) 1.23
Critical oxygen tension in rat brain: a combined (31)P-NMR and EPR oximetry study. Am J Physiol Regul Integr Comp Physiol (2000) 1.22
EPR spectrometer for clinical applications. Magn Reson Med (2005) 1.16
Intraphagosomal oxygen in stimulated macrophages. J Cell Physiol (1995) 1.16
Hypoxia-sensitive NMR contrast agents. Magn Reson Med (1986) 1.14
Noninvasive measurement of the pH inside the gut by using pH-sensitive nitroxides. An in vivo EPR study. Magn Reson Med (1996) 1.13
Assessment of cerebral pO2 by EPR oximetry in rodents: effects of anesthesia, ischemia, and breathing gas. Brain Res (1995) 1.13
High spatial resolution multi-site EPR oximetry. The use of convolution-based fitting method. J Magn Reson (2001) 1.12
Non-invasive in vivo characterization of release processes in biodegradable polymers by low-frequency electron paramagnetic resonance spectroscopy. Biomaterials (1996) 1.11
Paramagnetic changes during development of a transplanted AKR-J leukemia in mice as measured by electron spin resonance. Cancer Res (1973) 1.10
In vivo oximetry using EPR and India ink. Magn Reson Med (1995) 1.09
The effects of endotoxin on oxygen consumption of various cell types in vitro: an EPR oximetry study. Free Radic Biol Med (1995) 1.08
Use of nitroxides for assessing perfusion, oxygenation, and viability of tissues: in vivo EPR and MRI studies. Magn Reson Med (1996) 1.08
Electron spin resonance studies of changes in membrane fluidity of Chinese hamster ovary cells during the cell cycle. Biochim Biophys Acta (1980) 1.08
Estimation of oxygen distribution in RIF-1 tumors by diffusion model-based interpretation of pimonidazole hypoxia and eppendorf measurements. Radiat Res (2001) 1.07
Thioredoxin reductase mediates cell death effects of the combination of beta interferon and retinoic acid. Mol Cell Biol (1998) 1.06
Interaction of neuromelanin and iron in substantia nigra and other areas of human brain. Neuroscience (1996) 1.05
In vivo EPR dosimetry of accidental exposures to radiation: experimental results indicating the feasibility of practical use in human subjects. Appl Radiat Isot (2000) 1.05
Oxygen gradients in CHO cells: measurement and characterization by electron spin resonance. J Cell Physiol (1989) 1.04
An o-quinone form of estrogen produces free radicals in human breast cancer cells: correlation with DNA damage. Chem Res Toxicol (1994) 1.02
The effect of melanin on iron associated decomposition of hydrogen peroxide. Free Radic Biol Med (1988) 1.02
Kinetics of enzyme-mediated reduction of lipid soluble nitroxide spin labels by living cells. Biochim Biophys Acta (1988) 1.01
Reduced blood flow and oxygenation in SA-1 tumours after electrochemotherapy with cisplatin. Br J Cancer (2002) 1.01
Measurement of intracellular oxygen concentration using the spin label TEMPOL. Magn Reson Med (1985) 1.00
Effects of oxygen on the metabolism of nitroxide spin labels in cells. Biochemistry (1989) 0.99
Ion-exchange in melanin: an electron spin resonance study with lanthanide probes. Science (1976) 0.99
Changes of oxygen tension in experimental tumors after a single dose of X-ray irradiation. Cancer Res (1995) 0.99
Radiation effects on plasma electron-spin-resonance (ESR) spectra of cancer patients. Radiology (1972) 0.99
Novel free radicals in synthetic and natural pheomelanins: distinction between dopa melanins and cysteinyldopa melanins by ESR spectroscopy. Proc Natl Acad Sci U S A (1982) 0.98
The roles of neuromelanin, binding of metal ions, and oxidative cytotoxicity in the pathogenesis of Parkinson's disease: a hypothesis. J Neural Transm Park Dis Dement Sect (1994) 0.98
Effect on regrowth delay in a murine tumor of scheduling split-dose irradiation based on direct pO2 measurements by electron paramagnetic resonance oximetry. Radiat Res (1998) 0.98
Biochemical and biophysical applications of electron spin resonance. Methods Biochem Anal (1983) 0.97
Paramagnetic changes in cancer: DMBA-induced tumours studied in non-lyophilized and lyophilized tissues. Br J Cancer (1979) 0.96
Nonperturbing test for cytotoxicity in isolated cells and spheroids, using electron paramagnetic resonance. Magn Reson Med (1991) 0.96
Chemical and electrochemical reduction rates of cyclic nitroxides (nitroxyls). J Pharm Sci (1991) 0.96
DNA strand scission and free radical production in menadione-treated cells. Correlation with cytotoxicity and role of NADPH quinone acceptor oxidoreductase. J Biol Chem (1992) 0.95
Increased tumor oxygenation and drug uptake during anti-angiogenic weekly low dose cyclophosphamide enhances the anti-tumor effect of weekly tirapazamine. Curr Cancer Drug Targets (2009) 0.94
Effect of oxygen on freezing damage. 3. Modification by -mercaptoethylamine. Cryobiology (1971) 0.93
Hazards of radiation exposure for pregnant women. JAMA (1978) 0.93
In vivo oximetry using a nitroxide-liposome system. Magn Reson Med (1991) 0.93
EPR method for the measurement of cellular sulfhydryl groups. FEBS Lett (1991) 0.93
Electron spin resonance studies of carcinogenesis. Adv Cancer Res (1972) 0.93
Dextran magnetite as a liver contrast agent. Magn Reson Med (1991) 0.93
Cellular metabolism of water-soluble nitroxides: effect on rate of reduction of cell/nitroxide ratio, oxygen concentrations and permeability of nitroxides. Biochim Biophys Acta (1986) 0.92
Noninvasive assessment of cerebral oxygenation during acclimation to hypobaric hypoxia. J Cereb Blood Flow Metab (2000) 0.92
Total and paramagnetic metals in human substantia nigra and its neuromelanin. J Neural Transm Park Dis Dement Sect (1993) 0.91
Superoxide production by phagocytosing macrophages in relation to the intracellular distribution of oxygen. J Leukoc Biol (1998) 0.91
Distribution of 5-doxylstearic acid in the membranes of mammalian cells. Biochim Biophys Acta (1988) 0.91
Firefly flashing is controlled by gating oxygen to light-emitting cells. J Exp Biol (2001) 0.91
Reduced tumor oxygenation by treatment with vinblastine. Cancer Res (2001) 0.90
In vivo measurement of oxygen concentration using sonochemically synthesized microspheres. Biophys J (1994) 0.90
Influence of different anesthetics on skin oxygenation studied by electron paramagnetic resonance in vivo. Skin Pharmacol Physiol (2006) 0.90
Electron spin resonance-spin trapping. Detection of superoxide formation during aerobic microsomal reduction of nitro-compounds. Biochem Biophys Res Commun (1978) 0.90
Response to radioimmunotherapy correlates with tumor pO2 measured by EPR oximetry in human tumor xenografts. Radiat Res (2001) 0.90
Potential for EPR oximetry to guide treatment planning for tumors. Adv Exp Med Biol (1997) 0.89
Measurement of PO2 in liver using EPR oximetry. J Appl Physiol (1985) (1996) 0.89
Identity of the paramagnetic element found in increased concentrations in plasma of cancer patients and its relationship to other pathological processes. Cancer Res (1974) 0.89
Cardiac localization of 99mTc-(Sn)-pyrophosphate following irradiation of the chest. Radiology (1977) 0.89
Myocardial oxygen tension and relative capillary density in isolated perfused rat hearts. J Mol Cell Cardiol (1995) 0.89
BCL-2 is involved in preventing oxidant-induced cell death and in decreasing oxygen radical production. Redox Rep (2001) 0.89
The minocycline-induced thyroid pigment and several synthetic models: identification and characterization by electron paramagnetic resonance spectroscopy. J Pharmacol Exp Ther (1993) 0.88
Metabolism of nitroxide spin labels in subcellular fractions of rat liver. II. Reduction in the cytosol. Biochim Biophys Acta (1990) 0.88
In vivo localized ESR spectroscopy reflecting metabolism. Magn Reson Med (1989) 0.88
The apparent diffusion constant measured by MRI correlates with pO2 in a RIF-1 tumor. Magn Reson Med (1995) 0.88
International conference on singlet oxygen and related species in chemistry and biology: review and general discussion. Photochem Photobiol (1979) 0.88
Paramagnetic changes in cancer: growth of Walker 256 carcinoma studied in frozen and lyophilized tissues. Br J Cancer (1979) 0.88
Oxygen tension in a murine tumor: a combined EPR and MRI study. Magn Reson Med (1993) 0.87
MRI contrast enhanced study of cartilage proteoglycan degradation in the rabbit knee. Magn Reson Med (1997) 0.87
Endotoxin-induced changes in intrarenal pO2, measured by in vivo electron paramagnetic resonance oximetry and magnetic resonance imaging. Free Radic Biol Med (1996) 0.87
Oxidation of hydroxylamines to nitroxide spin labels in living cells. Biochim Biophys Acta (1988) 0.87
Electron spin resonance imaging of tissues with lipid-rich areas. Magn Reson Med (1988) 0.87
The safety of X-ray examination of radioisotope scan. JAMA (1978) 0.86
Effect of oxygen on freezing damage. II. Physical-chemical effects. Cryobiology (1971) 0.86
Separation and enrichment of the active component of carbon based paramagnetic materials for use in EPR oximetry. J Magn Reson (1998) 0.86
Identification by electron spin resonance of free radicals formed during the oxidation of 4-hydroxyanisole catalyzed by tyrosinase. J Biol Chem (1984) 0.86
Simultaneous measurement of intracellular and extracellular oxygen concentrations using a nitroxide-liposome system. Magn Reson Med (1993) 0.86
Toxic oxygen effects. Int Rev Cytol (1973) 0.85
Metabolism of nitroxide spin labels in subcellular fraction of rat liver. I. Reduction by microsomes. Biochim Biophys Acta (1990) 0.85
Electron spin resonance microscopy of an in vitro tumour model. Br J Cancer (1990) 0.85
Interactions of nitroxides with plasma and blood: effect on 1/T1 of water protons. Magn Reson Med (1990) 0.85
Effects of nitroxides on the magnetic field and temperature dependence of 1/T1 of solvent water protons. Magn Reson Med (1987) 0.85
Q-band EPR biodosimetry in tooth enamel microsamples: feasibility test and comparison with x-band. Health Phys (2007) 0.85