Published in Cancer Res on January 26, 2010
p27(Kip1), a double-edged sword in Shh-mediated medulloblastoma: Tumor accelerator and suppressor. Cell Cycle (2010) 1.02
RP58/ZNF238 directly modulates proneurogenic gene levels and is required for neuronal differentiation and brain expansion. Cell Death Differ (2011) 0.92
RP58 controls neuron and astrocyte differentiation by downregulating the expression of Id1-4 genes in the developing cortex. EMBO J (2012) 0.91
Flexible expressed region analysis for RNA-seq with derfinder. Nucleic Acids Res (2016) 0.82
Ankyrin repeat and BTB/POZ domain containing protein-2 inhibits the aggregation of alpha-synuclein: implications for Parkinson's disease. FEBS Lett (2013) 0.78
Regulators associated with clinical outcomes revealed by DNA methylation data in breast cancer. PLoS Comput Biol (2015) 0.76
Tumor-specific mutations in low-frequency genes affect their functional properties. J Neurooncol (2015) 0.76
Positive selection of the TRIM family regulatory region in primate genomes. Proc Biol Sci (2016) 0.75
Association of BTBD7 with Metastasis and Poor Prognosis in Non-Small-Cell Lung Cancer Patients. J Cancer (2015) 0.75
A simple knowledge-based mining method for exploring hidden key molecules in a human biomolecular network. BMC Syst Biol (2012) 0.75
Prediction of central nervous system embryonal tumour outcome based on gene expression. Nature (2002) 15.36
The genetic landscape of the childhood cancer medulloblastoma. Science (2010) 8.34
Gli and hedgehog in cancer: tumours, embryos and stem cells. Nat Rev Cancer (2002) 3.91
Sonic hedgehog controls stem cell behavior in the postnatal and adult brain. Development (2004) 3.30
A gene expression map of human chromosome 21 orthologues in the mouse. Nature (2002) 2.76
Duplication of 7q34 in pediatric low-grade astrocytomas detected by high-density single-nucleotide polymorphism-based genotype arrays results in a novel BRAF fusion gene. Brain Pathol (2008) 2.61
Central nervous system atypical teratoid/rhabdoid tumor: results of therapy in children enrolled in a registry. J Clin Oncol (2004) 2.53
Predisposition to atypical teratoid/rhabdoid tumor due to an inherited INI1 mutation. Pediatr Blood Cancer (2006) 2.48
A remarkably simple genome underlies highly malignant pediatric rhabdoid cancers. J Clin Invest (2012) 2.42
Spectrum of SMARCB1/INI1 mutations in familial and sporadic rhabdoid tumors. Pediatr Blood Cancer (2011) 2.41
Immunohistochemical analysis of hSNF5/INI1 in pediatric CNS neoplasms. Am J Surg Pathol (2004) 2.33
Hedgehog-Gli signalling and the growth of the brain. Nat Rev Neurosci (2002) 2.10
Genomic copy number determination in cancer cells from single nucleotide polymorphism microarrays based on quantitative genotyping corrected for aneuploidy. Genome Res (2009) 2.02
Inactivation of the Snf5 tumor suppressor stimulates cell cycle progression and cooperates with p53 loss in oncogenic transformation. Proc Natl Acad Sci U S A (2005) 1.96
Activating mutations in BRAF characterize a spectrum of pediatric low-grade gliomas. Neuro Oncol (2010) 1.93
Intensive multimodality treatment for children with newly diagnosed CNS atypical teratoid rhabdoid tumor. J Clin Oncol (2008) 1.92
The role of SMARCB1/INI1 in development of rhabdoid tumor. Cancer Biol Ther (2009) 1.82
Immunohistochemical analysis of hSNF5/INI1 distinguishes renal and extra-renal malignant rhabdoid tumors from other pediatric soft tissue tumors. Am J Surg Pathol (2004) 1.69
Genomic analysis using high-density single nucleotide polymorphism-based oligonucleotide arrays and multiplex ligation-dependent probe amplification provides a comprehensive analysis of INI1/SMARCB1 in malignant rhabdoid tumors. Clin Cancer Res (2009) 1.58
Atypical teratoid/rhabdoid tumor of the central nervous system: report on workshop. J Pediatr Hematol Oncol (2002) 1.57
Notch is oncogenic dominant in T-cell acute lymphoblastic leukemia. Blood (2011) 1.57
Alternative transcription exceeds alternative splicing in generating the transcriptome diversity of cerebellar development. Genome Res (2011) 1.52
High-resolution detection and mapping of genomic DNA alterations in neuroblastoma. Genes Chromosomes Cancer (2005) 1.47
Isochromosome 17q is a negative prognostic factor in poor-risk childhood medulloblastoma patients. Clin Cancer Res (2005) 1.40
Loss of the epigenetic tumor suppressor SNF5 leads to cancer without genomic instability. Mol Cell Biol (2008) 1.36
TP53, BRCA1, and BRCA2 tumor suppressor genes are not commonly mutated in survivors of Hodgkin's disease with second primary neoplasms. J Clin Oncol (2003) 1.23
INI1 expression is retained in composite rhabdoid tumors, including rhabdoid meningiomas. Mod Pathol (2005) 1.22
Atypical teratoid/rhabdoid tumor of the spine in an adult: case report and review of the literature. J Neurooncol (2007) 1.18
INI1 protein expression distinguishes atypical teratoid/rhabdoid tumor from choroid plexus carcinoma. J Neuropathol Exp Neurol (2005) 1.17
Loss of INI1 expression defines a unique subset of pediatric undifferentiated soft tissue sarcomas. Mod Pathol (2008) 1.12
Microdeletions and microduplications in patients with congenital heart disease and multiple congenital anomalies. Congenit Heart Dis (2011) 1.09
High-density single nucleotide polymorphism array analysis in patients with germline deletions of 22q11.2 and malignant rhabdoid tumor. Hum Genet (2007) 1.09
Oncolytic efficacy of recombinant vesicular stomatitis virus and myxoma virus in experimental models of rhabdoid tumors. Clin Cancer Res (2008) 1.08
No evidence for hypermethylation of the hSNF5/INI1 promoter in pediatric rhabdoid tumors. Genes Chromosomes Cancer (2002) 1.07
Atypical teratoid/rhabdoid tumor evolving from an optic pathway ganglioglioma: case study. Neuro Oncol (2006) 1.06
Epithelioid malignant peripheral nerve sheath tumor arising in a schwannoma, in a patient with "neuroblastoma-like" schwannomatosis and a novel germline SMARCB1 mutation. Am J Surg Pathol (2012) 1.06
Sonic hedgehog signaling in forebrain development and its interactions with pathways that modify its effects. Trends Cell Biol (2006) 1.04
Chromosome 22q deletions in atypical teratoid/rhabdoid tumors in adults. Brain Pathol (2005) 1.04
Differential modulation of Sonic-hedgehog-induced cerebellar granule cell precursor proliferation by the IGF signaling network. Dev Neurosci (2010) 1.03
SWI/SNF chromatin remodeling complexes and cancer. Am J Med Genet C Semin Med Genet (2014) 1.03
Implementation of high resolution single nucleotide polymorphism array analysis as a clinical test for patients with hematologic malignancies. Cancer Genet (2011) 1.03
Clinicopathologic comparison of familial versus sporadic atypical teratoid/rhabdoid tumors (AT/RT) of the central nervous system. Pediatr Blood Cancer (2010) 1.01
Atypical teratoid/rhabdoid tumor arising in the setting of a pleomorphic xanthoastrocytoma. J Neurooncol (2007) 1.01
Prediction of oligodendroglial tumor subtype and grade using perfusion weighted magnetic resonance imaging. J Neurosurg (2007) 1.00
Imprinted CDKN1C is a tumor suppressor in rhabdoid tumor and activated by restoration of SMARCB1 and histone deacetylase inhibitors. PLoS One (2009) 0.99
p16INK4A and p14ARF tumor suppressor pathways are deregulated in malignant rhabdoid tumors. J Neuropathol Exp Neurol (2011) 0.98
Panhandle and reverse-panhandle PCR enable cloning of der(11) and der(other) genomic breakpoint junctions of MLL translocations and identify complex translocation of MLL, AF-4, and CDK6. Proc Natl Acad Sci U S A (2002) 0.96
Educational paper: screening in cancer predisposition syndromes: guidelines for the general pediatrician. Eur J Pediatr (2011) 0.96
Bilateral pheochromocytomas, hemihyperplasia, and subtle somatic mosaicism: the importance of detecting low-level uniparental disomy. Am J Med Genet A (2013) 0.95
The full-length unprocessed hedgehog protein is an active signaling molecule. J Biol Chem (2009) 0.95
Novel cell lines established from pediatric brain tumors. J Neurooncol (2011) 0.92
ALK expression in rhabdomyosarcomas: correlation with histologic subtype and fusion status. Pediatr Dev Pathol (2009) 0.92
Sonic hedgehog mutations identified in holoprosencephaly patients can act in a dominant negative manner. Hum Genet (2008) 0.91
Molecularly confirmed primary malignant rhabdoid tumor of the urinary bladder: implications of accurate diagnosis. Ann Diagn Pathol (2011) 0.91
Direct reprogramming of melanocytes to neural crest stem-like cells by one defined factor. Stem Cells (2011) 0.91
Definition of genetic events directing the development of distinct types of brain tumors from postnatal neural stem/progenitor cells. Cancer Res (2012) 0.90
Formation of telomeric repeat-containing RNA (TERRA) foci in highly proliferating mouse cerebellar neuronal progenitors and medulloblastoma. J Cell Sci (2012) 0.88
Ablation of BRaf impairs neuronal differentiation in the postnatal hippocampus and cerebellum. PLoS One (2013) 0.88
Design and synthesis of inhibitors of Hedgehog signaling based on the alkaloid cyclopamine. Org Lett (2009) 0.88
Epithelioid sarcoma is associated with a high percentage of SMARCB1 deletions. Mod Pathol (2012) 0.87
Absence of oncogenic canonical pathway mutations in aggressive pediatric rhabdoid tumors. Pediatr Blood Cancer (2012) 0.87
Malignant rhabdoid tumor mimicking hepatoblastoma: a case report and literature review. Pediatr Dev Pathol (2007) 0.86
Parental heat exposure and risk of childhood brain tumor: a Children's Oncology Group study. Am J Epidemiol (2006) 0.86
Claudin-6 is a nonspecific marker for malignant rhabdoid and other pediatric tumors. Am J Surg Pathol (2012) 0.85
Clinical utilization of high-resolution single nucleotide polymorphism based oligonucleotide arrays in diagnostic studies of pediatric patients with solid tumors. Cancer Genet (2012) 0.85
Array analysis and molecular studies of INI1 in an infant with deletion 22q13 (Phelan-McDermid syndrome) and atypical teratoid/rhabdoid tumor. Am J Med Genet A (2009) 0.84
Temporal lobe pleomorphic xanthoastrocytoma and acquired BRAF mutation in an adolescent with the constitutional 22q11.2 deletion syndrome. J Neurooncol (2010) 0.84
Identification of genetic susceptibility to childhood cancer through analysis of genes in parallel. Cancer Genet (2011) 0.84
Cortical migration defects in mice expressing A-RAF from the B-RAF locus. Mol Cell Biol (2006) 0.84
Single nucleotide polymorphism array analysis of bone marrow failure patients reveals characteristic patterns of genetic changes. Br J Haematol (2013) 0.83
Chromosome band 7q34 deletions resulting in KIAA1549-BRAF and FAM131B-BRAF fusions in pediatric low-grade Gliomas. Brain Pathol (2014) 0.82
Atypical teratoid/rhabdoid tumor arising from the third cranial nerve. J Neuroophthalmol (2008) 0.82
Proximal-type Epithelioid Sarcoma of the Head and Neck (HN): A Study with Immunohistochemical and Molecular Analysis of SMARCB1. J Clin Exp Oncol (2013) 0.81
Acquired copy number neutral loss of heterozygosity of chromosome 7 associated with clonal haematopoiesis in a patient with Shwachman-Diamond syndrome. Br J Haematol (2012) 0.81
Rp58 is essential for the growth and patterning of the cerebellum and for glutamatergic and GABAergic neuron development. Development (2012) 0.80
Mutation of the INI1 gene in composite rhabdoid tumor of the endometrium. Hum Pathol (2007) 0.80
c-Met-mediated endothelial plasticity drives aberrant vascularization and chemoresistance in glioblastoma. J Clin Invest (2016) 0.80
SMARCB1-deficient Vulvar Neoplasms: A Clinicopathologic, Immunohistochemical, and Molecular Genetic Study of 14 Cases. Am J Surg Pathol (2015) 0.79
Ganglioglioma arising from dysplastic cortex. Epilepsia (2011) 0.79
Surgical treatment of a clival-C2 atypical teratoid/rhabdoid tumor. J Neurosurg Pediatr (2010) 0.78
Neuronal distribution of spatial in the developing cerebellum and hippocampus and its somatodendritic association with the kinesin motor KIF17. Exp Cell Res (2007) 0.78
Atypical teratoid/rhabdoid tumor in a patient with Beckwith-Wiedemann syndrome. Am J Med Genet A (2007) 0.78
Stereoselective synthesis of F-ring saturated estrone-derived inhibitors of Hedgehog signaling based on cyclopamine. Org Lett (2011) 0.77
Common polymorphic deletion of glutathione S-transferase theta predisposes to acquired aplastic anemia: Independent cohort and meta-analysis of 609 patients. Am J Hematol (2013) 0.77
Chromophobe renal cell carcinoma in a pediatric living-related kidney transplant recipient. Am J Kidney Dis (2005) 0.76
Cribriform neuroepithelial tumor arising in the lateral ventricle. Pediatr Dev Pathol (2013) 0.76
Design, synthesis, and biological evaluation of estrone-derived hedgehog signaling inhibitors. Tetrahedron (2011) 0.75
Studies directed toward the elucidation of the pharmacophore of steroid-based Sonic Hedgehog signaling inhibitors. Org Lett (2011) 0.75
SMARCB1/INI1 alterations and hepatoblastoma: another extrarenal rhabdoid tumor revealed? Pediatr Blood Cancer (2009) 0.75
Early molecular detection of central nervous system relapse in a child with systemic anaplastic large cell lymphoma: case report and review of the literature. Pediatr Blood Cancer (2005) 0.75