Published in Mol Vis on January 27, 2010
TSC2 mediates cellular energy response to control cell growth and survival. Cell (2003) 20.21
Shotgun identification of protein modifications from protein complexes and lens tissue. Proc Natl Acad Sci U S A (2002) 3.70
Age-related nuclear cataract-oxidation is the key. Exp Eye Res (2005) 3.61
TSC2: filling the GAP in the mTOR signaling pathway. Trends Biochem Sci (2004) 3.56
Disruption of alpha3 connexin gene leads to proteolysis and cataractogenesis in mice. Cell (1997) 3.10
Classification of gas5 as a multi-small-nucleolar-RNA (snoRNA) host gene and a member of the 5'-terminal oligopyrimidine gene family reveals common features of snoRNA host genes. Mol Cell Biol (1998) 3.08
Targeted ablation of connexin50 in mice results in microphthalmia and zonular pulverulent cataracts. J Cell Biol (1998) 2.85
Mutant DNA-binding domain of HSF4 is associated with autosomal dominant lamellar and Marner cataract. Nat Genet (2002) 2.21
Heat shock protein 27 phosphorylation: kinases, phosphatases, functions and pathology. Cell Mol Life Sci (2009) 2.09
Hsp27 (HspB1) and alphaB-crystallin (HspB5) as therapeutic targets. FEBS Lett (2007) 2.02
Connexin disorders of the ear, skin, and lens. Biochim Biophys Acta (2004) 1.75
HSF4 is required for normal cell growth and differentiation during mouse lens development. EMBO J (2004) 1.69
Molecular solutions to mammalian lens transparency. News Physiol Sci (2001) 1.62
Rhebbing up mTOR: new insights on TSC1 and TSC2, and the pathogenesis of tuberous sclerosis. Cancer Biol Ther (2003) 1.58
Lens proteomics: the accumulation of crystallin modifications in the mouse lens with age. Invest Ophthalmol Vis Sci (2002) 1.55
The mammalian HSF4 gene generates both an activator and a repressor of heat shock genes by alternative splicing. J Biol Chem (1999) 1.48
SASH1: a candidate tumor suppressor gene on chromosome 6q24.3 is downregulated in breast cancer. Oncogene (2003) 1.46
Global gene expression analysis of the developing postnatal mouse retina. Invest Ophthalmol Vis Sci (2004) 1.44
Hsp27 consolidates intracellular redox homeostasis by upholding glutathione in its reduced form and by decreasing iron intracellular levels. Antioxid Redox Signal (2005) 1.41
Hsp27 upregulation by HIF-1 signaling offers protection against retinal ischemia in rats. Invest Ophthalmol Vis Sci (2005) 1.40
The membrane proteome of the mouse lens fiber cell. Mol Vis (2009) 1.30
Characterization of a mutation in the lens-specific CP49 in the 129 strain of mouse. Invest Ophthalmol Vis Sci (2004) 1.29
Unique contribution of heat shock transcription factor 4 in ocular lens development and fiber cell differentiation. Genesis (2004) 1.25
Essential role for the Menkes ATPase in activation of extracellular superoxide dismutase: implication for vascular oxidative stress. FASEB J (2005) 1.25
Lens epithelial cell differentiation. Exp Eye Res (2002) 1.23
Catabolism in uremia: the impact of metabolic acidosis. J Am Soc Nephrol (1998) 1.16
Genetic factors influence cataract formation in alpha 3 connexin knockout mice. Dev Genet (1999) 1.15
Defining a link between gap junction communication, proteolysis, and cataract formation. J Biol Chem (2001) 1.13
Bfsp2 mutation found in mouse 129 strains causes the loss of CP49' and induces vimentin-dependent changes in the lens fibre cell cytoskeleton. Exp Eye Res (2004) 1.11
The fate of the Golgi apparatus and the endoplasmic reticulum during lens fiber cell differentiation. Invest Ophthalmol Vis Sci (1995) 1.04
HSP25 protects skeletal muscle cells against oxidative stress. Free Radic Biol Med (2004) 1.03
Stat3 modulates heat shock 27kDa protein expression in breast epithelial cells. Biochem Biophys Res Commun (2004) 1.02
Temporal expression of neuronal connexins during hippocampal ontogeny. Brain Res Brain Res Rev (2000) 1.01
Gene expression and discovery during lens regeneration in mouse: regulation of epithelial to mesenchymal transition and lens differentiation. Mol Vis (2006) 0.98
Targeted deletion of Dicer disrupts lens morphogenesis, corneal epithelium stratification, and whole eye development. Dev Dyn (2009) 0.98
ATF5 promotes cell survival through transcriptional activation of Hsp27 in H9c2 cells. Cell Biol Int (2007) 0.96
Microarray analysis of fiber cell maturation in the lens. FEBS Lett (2005) 0.93
Age-related cataracts in alpha3Cx46-knockout mice are dependent on a calpain 3 isoform. Invest Ophthalmol Vis Sci (2007) 0.93
A new lease of life for an old enzyme. Bioessays (1996) 0.92
Gene expression changes during cataract progression in Sparc null mice: differential regulation of mouse globins in the lens. Mol Vis (2004) 0.89
Acyl-CoA-binding protein is a potent m-calpain activator. J Biol Chem (2000) 0.87
Calcium-dependent and calcium-independent contractions in smooth muscles. Am J Med (2003) 0.87
Gene expression profiling in embryonic mouse lenses. Mol Vis (2006) 0.87
Increased IRP1 and IRP2 RNA binding activity accompanies a reduction of the labile iron pool in HFE-expressing cells. J Cell Physiol (2002) 0.86
Identification of proteins that modify cataract of mouse eye lens. Proteomics (2008) 0.86
Differentially expressed genes in the lens of mimecan-null mice. Mol Vis (2004) 0.84
Redox availability of lens iron and copper: implications for HO* generation in cataract. Redox Rep (1999) 0.82
Genetic control of ocular morphogenesis: defective lens development associated with ocular anomalies in C57BL/6 mice. Exp Eye Res (1993) 0.79
Identification of genes responsive to UV-A radiation in human lens epithelial cells using complementary DNA microarrays. Photochem Photobiol (2004) 0.79
Amino acid deficiency up-regulates specific mRNAs in murine embryonic cells. J Nutr (2002) 0.79
Eye lens proteomics: from global approach to detailed information about phakinin and gamma E and F crystallin genes. Proteomics (2005) 0.78
Characteristics of ethylnitrosourea-induced cataracts. Curr Eye Res (2009) 0.76
Lens connexins alpha3Cx46 and alpha8Cx50 interact with zonula occludens protein-1 (ZO-1). Mol Biol Cell (2003) 1.39
RNA interference targeting transforming growth factor-beta type II receptor suppresses ocular inflammation and fibrosis. Mol Vis (2004) 1.36
Molecular cloning, functional expression, and tissue distribution of a novel human gap junction-forming protein, connexin-31.9. Interaction with zona occludens protein-1. J Biol Chem (2002) 1.33
Identification of unique, differentiation stage-specific patterns of expression of the bromodomain-containing genes Brd2, Brd3, Brd4, and Brdt in the mouse testis. Gene Expr Patterns (2004) 1.31
Relation of response to treatment with dorzolamide in X-linked retinoschisis to the mechanism of functional loss in retinoschisin. Am J Ophthalmol (2008) 1.06
Calpain expression and activity during lens fiber cell differentiation. J Biol Chem (2009) 1.03
Mesenchymal stem cells improve cardiac conduction by upregulation of connexin 43 through paracrine signaling. Am J Physiol Heart Circ Physiol (2012) 0.97
Age-related cataracts in alpha3Cx46-knockout mice are dependent on a calpain 3 isoform. Invest Ophthalmol Vis Sci (2007) 0.93
Differences in expression patterns between mouse connexin-30.2 (Cx30.2) and its putative human orthologue, connexin-31.9. FEBS Lett (2003) 0.87
Identification of proteins that modify cataract of mouse eye lens. Proteomics (2008) 0.86
Electroretinographic findings in a patient with congenital stationary night blindness due to a novel NYX mutation. Ophthalmic Genet (2013) 0.84
Eye lens proteomics: from global approach to detailed information about phakinin and gamma E and F crystallin genes. Proteomics (2005) 0.78
High glucose-induced downregulation of connexin 30.2 promotes retinal vascular lesions: implications for diabetic retinopathy. Invest Ophthalmol Vis Sci (2013) 0.77