Donald J Davidson

Author PubWeight™ 47.16‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 A randomized controlled trial of peripheral blood mononuclear cell depletion in experimental human lung inflammation. Am J Respir Crit Care Med 2013 2.71
2 The human antimicrobial peptide LL-37 is a multifunctional modulator of innate immune responses. J Immunol 2002 2.57
3 Impact of LL-37 on anti-infective immunity. J Leukoc Biol 2004 2.01
4 Diagnostic importance of pulmonary interleukin-1beta and interleukin-8 in ventilator-associated pneumonia. Thorax 2009 1.87
5 Monocytes control second-phase neutrophil emigration in established lipopolysaccharide-induced murine lung injury. Am J Respir Crit Care Med 2012 1.82
6 A re-evaluation of the role of host defence peptides in mammalian immunity. Curr Protein Pept Sci 2005 1.78
7 Immunomodulatory activities of small host defense peptides. Antimicrob Agents Chemother 2005 1.67
8 The role of the purinergic P2X7 receptor in inflammation. J Inflamm (Lond) 2007 1.50
9 The human cationic peptide LL-37 induces activation of the extracellular signal-regulated kinase and p38 kinase pathways in primary human monocytes. J Immunol 2004 1.41
10 Antiviral activity and increased host defense against influenza infection elicited by the human cathelicidin LL-37. PLoS One 2011 1.39
11 Thrombospondin-1 mimetic peptide inhibitors of angiogenesis and tumor growth: design, synthesis, and optimization of pharmacokinetics and biological activities. J Med Chem 2005 1.31
12 Human beta-defensin 3 has immunosuppressive activity in vitro and in vivo. Eur J Immunol 2010 1.26
13 The human cationic host defense peptide LL-37 mediates contrasting effects on apoptotic pathways in different primary cells of the innate immune system. J Leukoc Biol 2006 1.25
14 Interaction and cellular localization of the human host defense peptide LL-37 with lung epithelial cells. Infect Immun 2005 1.24
15 Dying and necrotic neutrophils are anti-inflammatory secondary to the release of alpha-defensins. J Immunol 2009 1.21
16 RNA:DNA hybrids are a novel molecular pattern sensed by TLR9. EMBO J 2014 1.19
17 Primary immunodeficiency to pneumococcal infection due to a defect in Toll-like receptor signaling. J Pediatr 2004 1.12
18 Differential persistence among genomovars of the Burkholderia cepacia complex in a murine model of pulmonary infection. Infect Immun 2002 1.07
19 Animal models of cystic fibrosis. J Cyst Fibros 2004 1.06
20 Plasminogen kringle 5 induces apoptosis of brain microvessel endothelial cells: sensitization by radiation and requirement for GRP78 and LRP1. Cancer Res 2009 1.05
21 Prevalence of Toll-like receptor signalling defects in apparently healthy children who developed invasive pneumococcal infection. Clin Immunol 2006 1.03
22 Apoptosis of airway epithelial cells: human serum sensitive induction by the cathelicidin LL-37. Am J Respir Cell Mol Biol 2005 1.02
23 C5a mediates peripheral blood neutrophil dysfunction in critically ill patients. Am J Respir Crit Care Med 2009 1.01
24 C5a-mediated neutrophil dysfunction is RhoA-dependent and predicts infection in critically ill patients. Blood 2011 0.98
25 Secondary necrosis of apoptotic neutrophils induced by the human cathelicidin LL-37 is not proinflammatory to phagocytosing macrophages. J Leukoc Biol 2009 0.93
26 The human cathelicidin LL-37 preferentially promotes apoptosis of infected airway epithelium. Am J Respir Cell Mol Biol 2010 0.93
27 Trappin-2 promotes early clearance of Pseudomonas aeruginosa through CD14-dependent macrophage activation and neutrophil recruitment. Am J Pathol 2009 0.92
28 Cationic host defence peptides: potential as antiviral therapeutics. BioDrugs 2013 0.92
29 The human cathelicidin LL-37 has antiviral activity against respiratory syncytial virus. PLoS One 2013 0.88
30 Antiviral potential of cathelicidins. Future Microbiol 2014 0.85
31 The host defense peptide LL-37 selectively permeabilizes apoptotic leukocytes. Antimicrob Agents Chemother 2008 0.85
32 An integrated model for developing research skills in an undergraduate medical curriculum: appraisal of an approach using student selected components. Perspect Med Educ 2013 0.84
33 Pseudomonas aeruginosa: role in the pathogenesis of the CF lung lesion. Semin Respir Crit Care Med 2003 0.83
34 Persistence of Burkholderia multivorans within the pulmonary macrophage in the murine lung. Infect Immun 2004 0.82
35 Robust TLR4-induced gene expression patterns are not an accurate indicator of human immunity. J Transl Med 2010 0.77
36 Lysyl 4-aminobenzoic acid derivatives as potent small molecule mimetics of plasminogen kringle 5. Bioorg Med Chem Lett 2004 0.77
37 Correction: Human β-D-3 Exacerbates MDA5 but Suppresses TLR3 Responses to the Viral Molecular Pattern Mimic Polyinosinic:Polycytidylic Acid. PLoS Genet 2016 0.75
38 Reply: The alveolar macrophage and acute respiratory distress syndrome: a silent actor? Am J Respir Crit Care Med 2014 0.75
39 Letting the CAThelicidin out of the bag, as a therapeutic modulator of the adaptive immune system. Leuk Res 2005 0.75
40 Knee Arthroscopy Simulation: A Randomized Controlled Trial Evaluating the Effectiveness of the Imperial Knee Arthroscopy Cognitive Task Analysis (IKACTA) Tool. J Bone Joint Surg Am 2017 0.75