Published in Biofactors on February 11, 2010
Ajoene, a sulfur-rich molecule from garlic, inhibits genes controlled by quorum sensing. Antimicrob Agents Chemother (2012) 1.23
Spontaneous regression of septum pellucidum/forniceal pilocytic astrocytomas--possible role of Cannabis inhalation. Childs Nerv Syst (2011) 1.13
Redox regulation of T-cell function: from molecular mechanisms to significance in human health and disease. Antioxid Redox Signal (2012) 1.01
The immunomodulation and anti-inflammatory effects of garlic organosulfur compounds in cancer chemoprevention. Anticancer Agents Med Chem (2014) 0.95
Anti-inflammatory activity of sulfur-containing compounds from garlic. J Med Food (2012) 0.85
Apoptosis induction of human prostate carcinoma DU145 cells by diallyl disulfide via modulation of JNK and PI3K/AKT signaling pathways. Int J Mol Sci (2012) 0.79
Apoptosis induction of U937 human leukemia cells by diallyl trisulfide induces through generation of reactive oxygen species. J Biomed Sci (2012) 0.79
Investigating the responses of Cronobacter sakazakii to garlic-drived organosulfur compounds: a systematic study of pathogenic-bacterium injury by use of high-throughput whole-transcriptome sequencing and confocal micro-raman spectroscopy. Appl Environ Microbiol (2013) 0.78
Ameliorating effects of aged garlic extracts against Aβ-induced neurotoxicity and cognitive impairment. BMC Complement Altern Med (2013) 0.77
Apoptotic pathway induced by diallyl trisulfide in pancreatic cancer cells. World J Gastroenterol (2014) 0.77
Comment on: Not just a vampire repellent: the adverse effects of garlic supplements in surgery. Ann R Coll Surg Engl (2012) 0.75
The in Vitro Antibacterial Efficacy of Persian Green Tea Extract as an Intracanal Irrigant on Enterococcus faecalis Biofilm. Iran Endod J (2016) 0.75
The Karyopherin proteins, Crm1 and Karyopherin beta1, are overexpressed in cervical cancer and are critical for cancer cell survival and proliferation. Int J Cancer (2009) 1.97
A growth-related oncogene/CXC chemokine receptor 2 autocrine loop contributes to cellular proliferation in esophageal cancer. Cancer Res (2006) 1.66
The receptor tyrosine kinase Axl in cancer: biological functions and therapeutic implications. Int J Cancer (2013) 1.24
Structure-activity relationships in 4-aminoquinoline antiplasmodials. The role of the group at the 7-position. J Med Chem (2002) 1.20
The T-box transcription factor Tbx2: its role in development and possible implication in cancer. IUBMB Life (2010) 1.18
Lysyl oxidase-like 2 expression is increased in colon and esophageal tumors and associated with less differentiated colon tumors. Genes Chromosomes Cancer (2007) 1.13
Oesophageal cancer in Africa. IUBMB Life (2002) 1.08
Interference with hemozoin formation represents an important mechanism of schistosomicidal action of antimalarial quinoline methanols. PLoS Negl Trop Dis (2009) 1.06
Gene-environment interaction: the role of SULT1A1 and CYP3A5 polymorphisms as risk modifiers for squamous cell carcinoma of the oesophagus. Carcinogenesis (2005) 1.03
Screening of variants for lactase persistence/non-persistence in populations from South Africa and Ghana. BMC Genet (2009) 1.00
The cumulative effects of polymorphisms in the DNA mismatch repair genes and tobacco smoking in oesophageal cancer risk. PLoS One (2012) 0.99
A key role for early growth response-1 and nuclear factor-kappaB in mediating and maintaining GRO/CXCR2 proliferative signaling in esophageal cancer. Mol Cancer Res (2009) 0.99
Population-specific genetic associations with oesophageal squamous cell carcinoma in South Africa. Carcinogenesis (2011) 0.96
Genetic polymorphisms of alcohol metabolising enzymes: their role in susceptibility to oesophageal cancer. Clin Chem Lab Med (2008) 0.96
The 341C/T polymorphism in the GSTP1 gene is associated with increased risk of oesophageal cancer. BMC Genet (2010) 0.95
UV-mediated regulation of the anti-senescence factor Tbx2. J Biol Chem (2007) 0.95
CYP3A5 genotypes and risk of oesophageal cancer in two South African populations. Cancer Lett (2004) 0.94
Association of cytochrome P450 2E1 genetic polymorphisms with squamous cell carcinoma of the oesophagus. Clin Chem Lab Med (2005) 0.92
Health research in Africa: getting priorities right. Trop Med Int Health (2012) 0.92
[d4U]-spacer-[HI-236] double-drug inhibitors of HIV-1 reverse-transcriptase. Bioorg Med Chem (2010) 0.91
MicroRNA polymorphisms and environmental smoke exposure as risk factors for oesophageal squamous cell carcinoma. PLoS One (2013) 0.91
Association of a deletion of GSTT2B with an altered risk of oesophageal squamous cell carcinoma in a South African population: a case-control study. PLoS One (2011) 0.87
Distinct genetic association at the PLCE1 locus with oesophageal squamous cell carcinoma in the South African population. Carcinogenesis (2012) 0.87
Current developments in the synthesis and biological activity of HIV-1 double-drug inhibitors. Curr Med Chem (2007) 0.86
The role of inflammation in HPV infection of the Oesophagus. BMC Cancer (2013) 0.84
Aberrant methylation of the MSH3 promoter and distal enhancer in esophageal cancer patients exposed to first-hand tobacco smoke. J Cancer Res Clin Oncol (2014) 0.84
Conjugates of plumbagin and phenyl-2-amino-1-thioglucoside inhibit MshB, a deacetylase involved in the biosynthesis of mycothiol. Bioorg Med Chem (2010) 0.84
Mitigating effects of external ventricular drain usage in the management of severe head injury. Acta Neurochir (Wien) (2013) 0.82
Synthesis of 2-deoxy-2-C-alkylglucosides of myo-inositol as possible inhibitors of a N-deacetylase enzyme in the biosynthesis of mycothiol. Bioorg Med Chem Lett (2003) 0.82
In vitro antimalarial activity, β-haematin inhibition and structure-activity relationships in a series of quinoline triazoles. Eur J Med Chem (2013) 0.82
Feedback regulation of the α2(1) collagen gene via the Mek-Erk signaling pathway. IUBMB Life (2011) 0.81
Targeting neddylation in cancer therapy. Future Oncol (2012) 0.81
Bifunctional inhibition of human immunodeficiency virus type 1 reverse transcriptase: mechanism and proof-of-concept as a novel therapeutic design strategy. J Med Chem (2013) 0.80
Photolon, a chlorin e6 derivative, triggers ROS production and light-dependent cell death via necrosis. Int J Biochem Cell Biol (2007) 0.80
Structure-activity studies on the anti-proliferation activity of ajoene analogues in WHCO1 oesophageal cancer cells. Eur J Med Chem (2012) 0.80
A series of structurally simple chloroquine chemosensitizing dibemethin derivatives that inhibit chloroquine transport by PfCRT. Eur J Med Chem (2011) 0.80
Esophageal cancer risk in relation to GGC and CAG trinucleotide repeat lengths in the androgen receptor gene. Int J Cancer (2003) 0.80
The mechanism of the amidases: mutating the glutamate adjacent to the catalytic triad inactivates the enzyme due to substrate mispositioning. J Biol Chem (2013) 0.79
A role for Tbx2 in the regulation of the alpha2(1) collagen gene in human fibroblasts. J Cell Biochem (2007) 0.79
Penetrating knife injury to the frontal lobe--a case report. Ann R Coll Surg Engl (2010) 0.78
Progression of esophageal dysplasia to cancer. Ann N Y Acad Sci (2014) 0.78
Species-specific regulation of the alpha-2(I) procollagen gene by proximal promoter elements. IUBMB Life (2005) 0.78
Differential effects of novel tumour-derived p53 mutations on the transformation of NIH-3T3 cells. Biol Chem (2008) 0.78
Anti-proliferation activity of synthetic ajoene analogues on cancer cell-lines. Anticancer Agents Med Chem (2011) 0.78
Association of DCC, MLH1, GSTT1, GSTM1, and TP53 gene polymorphisms with colorectal cancer in Kazakhstan. Tumour Biol (2014) 0.77
Infrequent somatic deletion of the 5' region of the COL1A2 gene in oesophageal squamous cell cancer patients. Clin Chem Lab Med (2002) 0.77
Tumour cells down-regulate CCN2 gene expression in co-cultured fibroblasts in a Smad7- and ERK-dependent manner. Cell Commun Signal (2013) 0.77
Wnt/β-Catenin and MEK-ERK Signaling are Required for Fibroblast-Derived Extracellular Matrix-Mediated Endoderm Differentiation of Embryonic Stem Cells. Stem Cell Rev (2015) 0.77
Synthesis and anti-prion activity evaluation of aminoquinoline analogues. Eur J Med Chem (2010) 0.76
A novel role of annexin A2 in human type I collagen gene expression. J Cell Biochem (2015) 0.76
Stereoselective formation of quaternary stereogenic centers via alkylation of α-substituted malonate-imidazolidinones. J Org Chem (2014) 0.76
Solution chemistry of 1,15-bis(N,N-dimethyl)-5,11-dioxo-8-(N-benzyl)-1,4,8,12,15-pentaazapentadecane with metal ions of biological interest-Insights toward active metal ion containing therapeutics and diagnostic agents. Dalton Trans (2006) 0.75
Phosphorylation of the alpha 2(1) procollagen promoter binding proteins is required for promoter activity. IUBMB Life (2006) 0.75
4-Aminoquinoline Antimalarials Containing a Benzylmethylpyridylmethylamine Group are Active against Drug Resistant Plasmodium falciparum and Exhibit Oral Activity in Mice. J Med Chem (2017) 0.75
Addressing diseases in Africa. Clin Chem Lab Med (2002) 0.75
Perceptions of participating emergency nurses regarding an ED seasonal influenza vaccination program. J Emerg Nurs (2010) 0.75
Evaluation of DNA damage in a population of bats (Chiroptera) residing in an abandoned monazite mine. Mutat Res (2004) 0.75
Genotyping of alcohol dehydrogenase type 2 and 3 using a two-buffer polyacrylamide gel electrophoresis system. Clin Chem Lab Med (2003) 0.75