1
|
Oxidation of biological systems: oxidative stress phenomena, antioxidants, redox reactions, and methods for their quantification.
|
Toxicol Pathol
|
2003
|
3.99
|
2
|
Proliferative and nonproliferative lesions of the rat and mouse hepatobiliary system.
|
Toxicol Pathol
|
2010
|
2.09
|
3
|
Inhaled environmental combustion particles cause myocardial injury in the Wistar Kyoto rat.
|
Toxicol Sci
|
2003
|
1.66
|
4
|
Discovery of metabolomics biomarkers for early detection of nephrotoxicity.
|
Toxicol Pathol
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2009
|
1.64
|
5
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A critical role for ceramide synthase 2 in liver homeostasis: II. insights into molecular changes leading to hepatopathy.
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J Biol Chem
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2010
|
1.41
|
6
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Area under the curve as a dose metric for promotional responses following 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure.
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Toxicol Appl Pharmacol
|
2003
|
1.41
|
7
|
Susceptibility of cyclooxygenase-2-deficient mice to pulmonary fibrogenesis.
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Am J Pathol
|
2002
|
1.39
|
8
|
Extraskeletal osteosarcoma with cystic appearance in an aged Sprague-Dawley rat.
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Toxicol Pathol
|
2005
|
1.30
|
9
|
Dose-additive carcinogenicity of a defined mixture of "dioxin-like compounds".
|
Environ Health Perspect
|
2005
|
1.29
|
10
|
Mitochondrial toxicity in hearts of CD-1 mice following perinatal exposure to AZT, 3TC, or AZT/3TC in combination.
|
Environ Mol Mutagen
|
2007
|
1.10
|
11
|
Haploinsufficiency in DNA polymerase beta increases cancer risk with age and alters mortality rate.
|
Cancer Res
|
2006
|
1.08
|
12
|
Vascular and cardiac impairments in rats inhaling ozone and diesel exhaust particles.
|
Environ Health Perspect
|
2010
|
1.07
|
13
|
Differential attenuation of oxidative/nitrosative injuries in early prostatic neoplastic lesions in TRAMP mice by dietary antioxidants.
|
Prostate
|
2006
|
1.05
|
14
|
A grading scheme for the assessment of proliferative lesions of the mouse prostate in the TRAMP model.
|
Toxicol Pathol
|
2003
|
1.04
|
15
|
Susceptibility of signal transducer and activator of transcription-1-deficient mice to pulmonary fibrogenesis.
|
Am J Pathol
|
2005
|
1.03
|
16
|
Spontaneous lesions in control B6C3F1 mice and recommended sectioning of male accessory sex organs.
|
Toxicol Pathol
|
2002
|
1.03
|
17
|
Increase in cardiovascular pathology in female Sprague-Dawley rats following chronic treatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin and 3,3',4,4',5-pentachlorobiphenyl.
|
Cardiovasc Toxicol
|
2003
|
1.01
|
18
|
Terbutaline is a developmental neurotoxicant: effects on neuroproteins and morphology in cerebellum, hippocampus, and somatosensory cortex.
|
J Pharmacol Exp Ther
|
2003
|
1.01
|
19
|
Hepatic enzyme induction: histopathology.
|
Toxicol Pathol
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2010
|
0.99
|
20
|
Reduced sulfur mustard-induced skin toxicity in cyclooxygenase-2 knockout and celecoxib-treated mice.
|
Toxicol Appl Pharmacol
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2004
|
0.98
|
21
|
Overexpression of CYP2J2 provides protection against doxorubicin-induced cardiotoxicity.
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Am J Physiol Heart Circ Physiol
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2009
|
0.98
|
22
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Formation of cystic ovarian follicles associated with elevated luteinizing hormone requires estrogen receptor-beta.
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Endocrinology
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2004
|
0.97
|
23
|
Mitochondrial damage revealed by morphometric and semiquantitative analysis of mouse pup cardiomyocytes following in utero and postnatal exposure to zidovudine and lamivudine.
|
Toxicol Sci
|
2004
|
0.96
|
24
|
The role of particulate matter-associated zinc in cardiac injury in rats.
|
Environ Health Perspect
|
2008
|
0.96
|
25
|
One-month diesel exhaust inhalation produces hypertensive gene expression pattern in healthy rats.
|
Environ Health Perspect
|
2008
|
0.95
|
26
|
Histological biocompatibility of a stainless steel miniature glaucoma drainage device in humans: a case report.
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Toxicol Pathol
|
2009
|
0.94
|
27
|
cAMP-dependent oncogenic action of Rap1b in the thyroid gland.
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J Biol Chem
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2004
|
0.94
|
28
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A critical comparison of murine pathology and epidemiological data of TCDD, PCB126, and PeCDF.
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Toxicol Pathol
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2007
|
0.94
|
29
|
Dimethylarsinic acid: results of chronic toxicity/oncogenicity studies in F344 rats and in B6C3F1 mice.
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Toxicology
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2006
|
0.94
|
30
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Toxicity and carcinogenicity of riddelliine in rats and mice.
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Toxicol Lett
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2003
|
0.93
|
31
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Incidences of selected lesions in control female Harlan Sprague-Dawley rats from two-year studies performed by the National Toxicology Program.
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Toxicol Pathol
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2005
|
0.93
|
32
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Comparative long-term preclinical safety evaluation of two glatiramoid compounds (glatiramer Acetate, Copaxone(R), and TV-5010, protiramer) in rats and monkeys.
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Toxicol Pathol
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2011
|
0.92
|
33
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An investigation of the effects of late-onset dietary restriction on prostate cancer development in the TRAMP mouse.
|
Toxicol Pathol
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2005
|
0.91
|
34
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Reprogrammed and transmissible intestinal microbiota confer diminished susceptibility to induced colitis in TMF-/- mice.
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Proc Natl Acad Sci U S A
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2014
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0.91
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35
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Ephedrine plus caffeine causes age-dependent cardiovascular responses in Fischer 344 rats.
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Am J Physiol Heart Circ Physiol
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2005
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0.90
|
36
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Synergistic effect of influenza a virus on endotoxin-induced mortality in rat pups: a potential model for sudden infant death syndrome.
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Pediatr Res
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2002
|
0.90
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37
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Novel double coated nanocapsules for intestinal delivery and enhanced oral bioavailability of tacrolimus, a P-gp substrate drug.
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J Control Release
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2008
|
0.90
|
38
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Classification of proliferative hepatocellular lesions in harlan sprague-dawley rats chronically exposed to dioxin-like compounds.
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Toxicol Pathol
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2005
|
0.90
|
39
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Surface characterization and biocompatibility of restorative resin containing nanoparticles.
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Biomacromolecules
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2008
|
0.89
|
40
|
Cardiovascular and blood coagulative effects of pulmonary zinc exposure.
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Toxicol Appl Pharmacol
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2005
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0.89
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41
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Poly(sebacic acid-co-ricinoleic acid) biodegradable carrier for paclitaxel: in vitro release and in vivo toxicity.
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J Biomed Mater Res A
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2004
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0.89
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42
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Subchronic inhalation of zinc sulfate induces cardiac changes in healthy rats.
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Toxicol Appl Pharmacol
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2008
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0.89
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43
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Loss of TMF/ARA160 protein renders colonic mucus refractory to bacterial colonization and diminishes intestinal susceptibility to acute colitis.
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J Biol Chem
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2012
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0.87
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44
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Fourteen-week toxicity study of green tea extract in rats and mice.
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Toxicol Pathol
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2010
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0.86
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45
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Gingival carcinogenicity in female Harlan Sprague-Dawley rats following two-year oral treatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin and dioxin-like compounds.
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Toxicol Sci
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2004
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0.86
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46
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Effect of diet and animal care/housing protocols on body weight, survival, tumor incidences, and nephropathy severity of F344 rats in chronic studies.
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Toxicol Pathol
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2003
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0.86
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47
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Respiratory tract lesions in noninhalation studies.
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Toxicol Pathol
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2007
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0.86
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48
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Drug-induced thrombosis--experimental, clinical, and mechanistic considerations.
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Toxicol Pathol
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2007
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0.86
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49
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Proceedings of the 2010 National Toxicology Program Satellite Symposium.
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Toxicol Pathol
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2010
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0.86
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50
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Gentamicin extended release from an injectable polymeric implant.
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J Control Release
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2006
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0.86
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51
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Histopathology and apoptosis in an animal model of reversible renal injury.
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Exp Toxicol Pathol
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2010
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0.85
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52
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The effect of chronic progressive nephropathy on the incidence of renal tubule cell neoplasms in control male F344 rats.
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Toxicol Pathol
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2003
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0.85
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53
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Toxicity and carcinogenicity of the water disinfection byproduct, dibromoacetic acid, in rats and mice.
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Toxicology
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2006
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0.85
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54
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Early effects of iodine on DNA synthesis in sulfur mustard-induced skin lesions.
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Arch Toxicol
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2006
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0.84
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55
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Biomarkers of Oxidative Stress Study IV: ozone exposure of rats and its effect on antioxidants in plasma and bronchoalveolar lavage fluid.
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Free Radic Biol Med
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2011
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0.84
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56
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Occult cardiotoxicity--toxic effects on cardiac ischemic tolerance.
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Toxicol Pathol
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2009
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0.84
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57
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Safety and biodistribution profile of placental-derived mesenchymal stromal cells (PLX-PAD) following intramuscular delivery.
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Toxicol Pathol
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2009
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0.84
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58
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Intratumoral delivery of paclitaxel for treatment of orthotopic prostate cancer.
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J Pharm Sci
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2009
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0.84
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59
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Induction of thyroid lesions in 14-week toxicity studies of 2 and 4-methylimidazole in Fischer 344/N rats and B6C3F1 mice.
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Arch Toxicol
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2005
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0.84
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60
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Characterization of liver toxicity in F344/N rats and B6C3F1 mice after exposure to a flame retardant containing lower molecular weight polybrominated diphenyl ethers.
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Exp Toxicol Pathol
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2008
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0.84
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61
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Gastrointestinal hyperplasia with altered expression of DNA polymerase beta.
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PLoS One
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2009
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0.83
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62
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Immunohistochemical analysis of expressions of hepatic cytochrome P450 in F344 rats following oral treatment with kava extract.
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Exp Toxicol Pathol
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2006
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0.83
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63
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Mechanisms of exocrine pancreatic toxicity induced by oral treatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin in female Harlan Sprague-Dawley Rats.
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Toxicol Sci
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2005
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0.83
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64
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Systemic imbalance of essential metals and cardiac gene expression in rats following acute pulmonary zinc exposure.
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J Toxicol Environ Health A
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2006
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0.83
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65
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Involvement of tumor necrosis factor-alpha in sulfur mustard-induced skin lesion; effect of topical iodine.
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Arch Toxicol
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2005
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0.83
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66
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Characterization of bronchiolar metaplasia of the alveolar epithelium in female Sprague-Dawley rats exposed to 3,3',4,4',5-pentachlorobiphenyl (PCB126).
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Toxicol Pathol
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2004
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0.83
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67
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Enhancing pigmentation via activation of A3 adenosine receptors in B16 melanoma cells and in human skin explants.
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Exp Dermatol
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2012
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0.83
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68
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Proceedings of the 2011 National Toxicology Program Satellite Symposium.
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Toxicol Pathol
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2011
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0.82
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69
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Regulated over-expression of DNA polymerase beta mediates early onset cataract in mice.
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DNA Repair (Amst)
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2003
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0.82
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70
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Reproductive lesions in female Harlan Sprague-Dawley rats following two-year oral treatment with dioxin and dioxin-like compounds.
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Toxicol Pathol
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2009
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0.82
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71
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Hepatocellular carcinomas in B6C3F1 mice treated with Ginkgo biloba extract for two years differ from spontaneous liver tumors in cancer gene mutations and genomic pathways.
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Toxicol Pathol
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2012
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0.82
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72
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Biocompatibility and safety evaluation of a ricinoleic acid-based poly(ester-anhydride) copolymer after implantation in rats.
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J Biomed Mater Res A
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2010
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0.82
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73
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Protective effect of topical iodine containing anti-inflammatory drugs against sulfur mustard-induced skin lesions.
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Arch Toxicol
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2003
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0.82
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74
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Dietary salt exacerbates isoproterenol-induced cardiomyopathy in rats.
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Toxicol Pathol
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2011
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0.81
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75
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Particulate matter inhalation exacerbates cardiopulmonary injury in a rat model of isoproterenol-induced cardiomyopathy.
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Inhal Toxicol
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2010
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0.81
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76
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Carcinogenic mode of action of folpet in mice and evaluation of its relevance to humans.
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Crit Rev Toxicol
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2010
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0.81
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77
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Myocardial mitochondrial injury induced by pulmonary exposure to particulate matter in rats.
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Toxicol Pathol
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2012
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0.81
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78
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Toxicity and carcinogenicity of Elmiron in F344/N rats and B6C3F1 mice following 2 years of gavage administration.
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Arch Toxicol
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2003
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0.81
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79
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Anti-HER2 cationic immunoemulsion as a potential targeted drug delivery system for the treatment of prostate cancer.
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Cancer Res
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2007
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0.81
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80
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Alteration in regulation of inflammatory response to influenza a virus and endotoxin in suckling rat pups: a potential relationship to sudden infant death syndrome.
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FEMS Immunol Med Microbiol
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2004
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0.81
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81
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Treatment of osteomyelitis in rats by injection of degradable polymer releasing gentamicin.
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J Control Release
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2008
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0.81
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82
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Adrenergic differentiation and Ret expression in rat pheochromocytomas.
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Endocr Pathol
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2008
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0.81
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83
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Induction of interleukin-1beta, tumour necrosis factor-alpha and apoptosis in mouse organs by amphotericin B is neutralized by conjugation with arabinogalactan.
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J Antimicrob Chemother
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2005
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0.81
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84
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Comparison of chronic toxicity and carcinogenicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in 2-year bioassays in female Sprague-Dawley rats.
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Mol Nutr Food Res
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2006
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0.81
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85
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The toxicity and pathology of selected dietary herbal medicines.
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Toxicol Pathol
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2012
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0.81
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86
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Pulmonary thrombosis in the mouse following intravenous administration of quantum dot-labeled mesenchymal cells.
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Nanotoxicology
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2010
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0.81
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87
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A chemically induced rat model of hemolysis with disseminated thrombosis.
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Cardiovasc Toxicol
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2002
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0.80
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88
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A comparative immunohistochemical study of spontaneous and chemically induced pheochromocytomas in B6C3F1 mice.
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Endocr Pathol
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2003
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0.80
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89
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Subchronic pulmonary pathology, iron overload, and transcriptional activity after Libby amphibole exposure in rat models of cardiovascular disease.
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Environ Health Perspect
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2011
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0.80
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90
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Epididymal sperm granuloma induced by chronic administration of 2-methylimidazole in B6C3F1 mice.
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Toxicol Pathol
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2005
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0.80
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91
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Testosterone deficiency accompanied by testicular and epididymal abnormalities in TMF(-/-) mice.
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Mol Cell Endocrinol
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2012
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0.80
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92
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Follicular epithelial cell hypertrophy induced by chronic oral administration of 2,3,7,8-tetrachlorodibenzo-p-dioxin in female Harlan Sprague-Dawley rats.
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Toxicol Pathol
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2004
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0.80
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93
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Characterization of spontaneous and chemically induced cardiac lesions in rodent model systems: the national toxicology program experience.
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Cardiovasc Toxicol
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2005
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0.80
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94
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Evidence for infection, inflammation and shock in sudden infant death: parallels between a neonatal rat model of sudden death and infants who died of sudden infant death syndrome.
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Innate Immun
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2008
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0.80
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95
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Pulmonary lesions in female Harlan Sprague-Dawley rats following two-year oral treatment with dioxin-like compounds.
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Toxicol Pathol
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2007
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0.80
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96
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Pulmonary inflammatory and fibrotic responses in Fischer 344 rats after intratracheal instillation exposure to Libby amphibole.
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J Toxicol Environ Health A
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2011
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Systemic vascular disease in male B6C3F1 mice exposed to particulate matter by inhalation: studies conducted by the National Toxicology Program.
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Toxicol Pathol
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2002
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0.79
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98
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Spontaneous aortitis in the Balb/c mouse.
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Toxicol Pathol
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2009
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99
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Comparative phenotypic assessment of cardiac pathology, physiology, and gene expression in C3H/HeJ, C57BL/6J, and B6C3F1/J mice.
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Toxicol Pathol
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2010
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0.79
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100
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Sumas Mountain chrysotile induces greater lung fibrosis in Fischer344 rats than Libby amphibole, El Dorado tremolite, and Ontario ferroactinolite.
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Toxicol Sci
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2012
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0.79
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101
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Immunohistochemical features of 3,3',4,4'-tetrachloroazobenzene-induced rat gingival lesions.
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Toxicol Pathol
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2012
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0.79
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102
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Amelioration of experimental autoimmune encephalitis by novel peptides: involvement of T regulatory cells.
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J Autoimmun
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2010
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0.79
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103
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Diesel exhaust induced pulmonary and cardiovascular impairment: the role of hypertension intervention.
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Toxicol Appl Pharmacol
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2013
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0.79
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104
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Association of adrenal pheochromocytoma and lung pathology in inhalation studies with particulate compounds in the male F344 rat--the National Toxicology Program experience.
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Toxicol Pathol
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2002
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0.79
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105
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Liver toxicity and carcinogenicity in F344/N rats and B6C3F1 mice exposed to Kava Kava.
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Food Chem Toxicol
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2011
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0.79
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106
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The role of cardiovascular disease-associated iron overload in Libby amphibole-induced acute pulmonary injury and inflammation.
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Inhal Toxicol
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2011
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0.78
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107
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A natural antioxidant mixture from spinach does not have estrogenic or antiestrogenic activity in immature CD-1 mice.
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J Nutr
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2003
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0.78
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108
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The influence of fasting on blood glucose, triglycerides, cholesterol, and alkaline phosphatase in rats.
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Vet Clin Pathol
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0.78
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109
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Chemical-induced atrial thrombosis in NTP rodent studies.
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Toxicol Pathol
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2005
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0.78
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110
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Composition, efficacy, and safety of spinach extracts.
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Nutr Cancer
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2003
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0.78
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111
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Acrylonitrile is a multisite carcinogen in male and female B6C3F1 mice.
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Toxicol Sci
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2002
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0.78
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112
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Subcutaneous and intraperitoneal lipogranulomas following subcutaneous injection of olive oil in Sprague-Dawley rats.
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Toxicol Pathol
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2009
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0.78
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113
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Morphologic aspects of rodent cardiotoxicity in a retrospective evaluation of National Toxicology Program studies.
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Toxicol Pathol
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2011
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114
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Inflammatory and chloracne-like skin lesions in B6C3F1 mice exposed to 3,3',4,4'-tetrachloroazobenzene for 2 years.
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Toxicology
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2009
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0.78
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115
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Assessment of the safety and biodistribution of a regulated AAV2 gene transfer vector after delivery to murine submandibular glands.
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Toxicol Sci
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2011
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0.78
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116
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Thyroid follicular lesions induced by oral treatment for 2 years with 2,3,7,8-tetrachlorodibenzo-p-dioxin and dioxin-like compounds in female Harlan Sprague-Dawley rats.
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2010
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0.78
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117
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Gene expression profiling of rat pheochromocytoma.
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Ann N Y Acad Sci
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Aging and susceptibility to toluene in rats: a pharmacokinetic, biomarker, and physiological approach.
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J Toxicol Environ Health A
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Comparative long-term toxicity of Libby amphibole and amosite asbestos in rats after single or multiple intratracheal exposures.
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Cardiac damage in rodents after exposure to bis(2-chloroethoxy)methane.
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Carrier free rapamycin loaded drug eluting stent: in vitro and in vivo evaluation.
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Cardiopulmonary responses of Wistar Kyoto, spontaneously hypertensive, and stroke-prone spontaneously hypertensive rats to particulate matter (PM) exposure.
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Age and dose sensitivities in the 2-butoxyethanol F344 rat model of hemolytic anemia and disseminated thrombosis.
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Exp Toxicol Pathol
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2-Butoxyethanol enhances the adherence of red blood cells.
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Disseminated thrombosis-induced growth plate necrosis in rat: a unique model for growth plate arrest.
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Drug-induced thrombosis: an update.
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Multisite carcinogenicity and respiratory toxicity of inhaled 1-bromopropane in rats and mice.
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A novel nanocapsule delivery system to overcome intestinal degradation and drug transport limited absorption of P-glycoprotein substrate drugs.
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Pharm Res
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Vitamin A deficiency aggravates rotavirus infection in CD-1 mice through extensive involvement of the gut.
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Hemostatic activation in a chemically induced rat model of severe hemolysis and thrombosis.
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Thromb Res
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Ischemic brain damage after ketamine and xylazine treatment in a young laboratory monkey (Macaca fascicularis).
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Evaluation of glycosaminoglycans content and 5-hydroxytryptamine 2B receptor in the heart valves of Sprague-Dawley rats with spontaneous mitral valvulopathy--a possible exacerbation by dl-amphetamine sulfate in Fischer 344 rats?
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Occult cardiotoxicity: subtoxic dosage of Bis(2-chloroethoxy)methane impairs cardiac response to simulated ischemic injury.
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Bis(2-chloroethoxy)methane-induced mitochondrial and myofibrillar damage: short-term time-course study.
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Protective effect of topical iodine preparations upon heat-induced and hydrofluoric acid-induced skin lesions.
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Hexachlorobenzene-induced incisor degeneration in Sprague-Dawley rats.
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Intestinal lymphangiectasis and lipidosis in rats following subchronic exposure to indole-3-carbinol via oral gavage.
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Computed tomography of Lipiodol-loaded biodegradable pasty polymer for implant visualization.
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Repeated dose toxicity and relative potency of 1,2,3,4,6,7-hexachloronaphthalene (PCN 66) 1,2,3,5,6,7-hexachloronaphthalene (PCN 67) compared to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) for induction of CYP1A1, CYP1A2 and thymic atrophy in female Harlan Sprague-Dawley rats.
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Toxicology
|
2012
|
0.75
|
140
|
Letter to the editor.
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Toxicol Pathol
|
2010
|
0.75
|
141
|
Investigating the potential for toxicity from long-term use of the herbal products, goldenseal and milk thistle.
|
Toxicol Pathol
|
2011
|
0.75
|
142
|
Spontaneous glomerulonephritis in Göttingen minipigs.
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Toxicol Pathol
|
2011
|
0.75
|
143
|
2-Butoxyethanol female-rat model of hemolysis and disseminated thrombosis: X-ray characterization of osteonecrosis and growth-plate suppression.
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Toxicol Pathol
|
2005
|
0.75
|
144
|
Forestomach tumor induction by 2,4-hexadienal in F344N rats and B6C3F1 mice.
|
Arch Toxicol
|
2003
|
0.75
|
145
|
Application of a statistical dynamic model investigating the short-term cellular kinetics induced by riddelliine, a hepatic endothelial carcinogen.
|
Toxicol Sci
|
2004
|
0.75
|
146
|
Does terbutaline damage the developing heart?
|
Birth Defects Res B Dev Reprod Toxicol
|
2003
|
0.75
|
147
|
Foreign-body granulomas within intramyocardial arteries in a transcoronary safety assessment in pigs.
|
Toxicol Pathol
|
2008
|
0.75
|