Abraham Nyska

Author PubWeight™ 124.60‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Oxidation of biological systems: oxidative stress phenomena, antioxidants, redox reactions, and methods for their quantification. Toxicol Pathol 2003 3.99
2 Proliferative and nonproliferative lesions of the rat and mouse hepatobiliary system. Toxicol Pathol 2010 2.09
3 Inhaled environmental combustion particles cause myocardial injury in the Wistar Kyoto rat. Toxicol Sci 2003 1.66
4 Discovery of metabolomics biomarkers for early detection of nephrotoxicity. Toxicol Pathol 2009 1.64
5 A critical role for ceramide synthase 2 in liver homeostasis: II. insights into molecular changes leading to hepatopathy. J Biol Chem 2010 1.41
6 Area under the curve as a dose metric for promotional responses following 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure. Toxicol Appl Pharmacol 2003 1.41
7 Susceptibility of cyclooxygenase-2-deficient mice to pulmonary fibrogenesis. Am J Pathol 2002 1.39
8 Extraskeletal osteosarcoma with cystic appearance in an aged Sprague-Dawley rat. Toxicol Pathol 2005 1.30
9 Dose-additive carcinogenicity of a defined mixture of "dioxin-like compounds". Environ Health Perspect 2005 1.29
10 Mitochondrial toxicity in hearts of CD-1 mice following perinatal exposure to AZT, 3TC, or AZT/3TC in combination. Environ Mol Mutagen 2007 1.10
11 Haploinsufficiency in DNA polymerase beta increases cancer risk with age and alters mortality rate. Cancer Res 2006 1.08
12 Vascular and cardiac impairments in rats inhaling ozone and diesel exhaust particles. Environ Health Perspect 2010 1.07
13 Differential attenuation of oxidative/nitrosative injuries in early prostatic neoplastic lesions in TRAMP mice by dietary antioxidants. Prostate 2006 1.05
14 A grading scheme for the assessment of proliferative lesions of the mouse prostate in the TRAMP model. Toxicol Pathol 2003 1.04
15 Susceptibility of signal transducer and activator of transcription-1-deficient mice to pulmonary fibrogenesis. Am J Pathol 2005 1.03
16 Spontaneous lesions in control B6C3F1 mice and recommended sectioning of male accessory sex organs. Toxicol Pathol 2002 1.03
17 Increase in cardiovascular pathology in female Sprague-Dawley rats following chronic treatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin and 3,3',4,4',5-pentachlorobiphenyl. Cardiovasc Toxicol 2003 1.01
18 Terbutaline is a developmental neurotoxicant: effects on neuroproteins and morphology in cerebellum, hippocampus, and somatosensory cortex. J Pharmacol Exp Ther 2003 1.01
19 Hepatic enzyme induction: histopathology. Toxicol Pathol 2010 0.99
20 Reduced sulfur mustard-induced skin toxicity in cyclooxygenase-2 knockout and celecoxib-treated mice. Toxicol Appl Pharmacol 2004 0.98
21 Overexpression of CYP2J2 provides protection against doxorubicin-induced cardiotoxicity. Am J Physiol Heart Circ Physiol 2009 0.98
22 Formation of cystic ovarian follicles associated with elevated luteinizing hormone requires estrogen receptor-beta. Endocrinology 2004 0.97
23 Mitochondrial damage revealed by morphometric and semiquantitative analysis of mouse pup cardiomyocytes following in utero and postnatal exposure to zidovudine and lamivudine. Toxicol Sci 2004 0.96
24 The role of particulate matter-associated zinc in cardiac injury in rats. Environ Health Perspect 2008 0.96
25 One-month diesel exhaust inhalation produces hypertensive gene expression pattern in healthy rats. Environ Health Perspect 2008 0.95
26 Histological biocompatibility of a stainless steel miniature glaucoma drainage device in humans: a case report. Toxicol Pathol 2009 0.94
27 cAMP-dependent oncogenic action of Rap1b in the thyroid gland. J Biol Chem 2004 0.94
28 A critical comparison of murine pathology and epidemiological data of TCDD, PCB126, and PeCDF. Toxicol Pathol 2007 0.94
29 Dimethylarsinic acid: results of chronic toxicity/oncogenicity studies in F344 rats and in B6C3F1 mice. Toxicology 2006 0.94
30 Toxicity and carcinogenicity of riddelliine in rats and mice. Toxicol Lett 2003 0.93
31 Incidences of selected lesions in control female Harlan Sprague-Dawley rats from two-year studies performed by the National Toxicology Program. Toxicol Pathol 2005 0.93
32 Comparative long-term preclinical safety evaluation of two glatiramoid compounds (glatiramer Acetate, Copaxone(R), and TV-5010, protiramer) in rats and monkeys. Toxicol Pathol 2011 0.92
33 An investigation of the effects of late-onset dietary restriction on prostate cancer development in the TRAMP mouse. Toxicol Pathol 2005 0.91
34 Reprogrammed and transmissible intestinal microbiota confer diminished susceptibility to induced colitis in TMF-/- mice. Proc Natl Acad Sci U S A 2014 0.91
35 Ephedrine plus caffeine causes age-dependent cardiovascular responses in Fischer 344 rats. Am J Physiol Heart Circ Physiol 2005 0.90
36 Synergistic effect of influenza a virus on endotoxin-induced mortality in rat pups: a potential model for sudden infant death syndrome. Pediatr Res 2002 0.90
37 Novel double coated nanocapsules for intestinal delivery and enhanced oral bioavailability of tacrolimus, a P-gp substrate drug. J Control Release 2008 0.90
38 Classification of proliferative hepatocellular lesions in harlan sprague-dawley rats chronically exposed to dioxin-like compounds. Toxicol Pathol 2005 0.90
39 Surface characterization and biocompatibility of restorative resin containing nanoparticles. Biomacromolecules 2008 0.89
40 Cardiovascular and blood coagulative effects of pulmonary zinc exposure. Toxicol Appl Pharmacol 2005 0.89
41 Poly(sebacic acid-co-ricinoleic acid) biodegradable carrier for paclitaxel: in vitro release and in vivo toxicity. J Biomed Mater Res A 2004 0.89
42 Subchronic inhalation of zinc sulfate induces cardiac changes in healthy rats. Toxicol Appl Pharmacol 2008 0.89
43 Loss of TMF/ARA160 protein renders colonic mucus refractory to bacterial colonization and diminishes intestinal susceptibility to acute colitis. J Biol Chem 2012 0.87
44 Fourteen-week toxicity study of green tea extract in rats and mice. Toxicol Pathol 2010 0.86
45 Gingival carcinogenicity in female Harlan Sprague-Dawley rats following two-year oral treatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin and dioxin-like compounds. Toxicol Sci 2004 0.86
46 Effect of diet and animal care/housing protocols on body weight, survival, tumor incidences, and nephropathy severity of F344 rats in chronic studies. Toxicol Pathol 2003 0.86
47 Respiratory tract lesions in noninhalation studies. Toxicol Pathol 2007 0.86
48 Drug-induced thrombosis--experimental, clinical, and mechanistic considerations. Toxicol Pathol 2007 0.86
49 Proceedings of the 2010 National Toxicology Program Satellite Symposium. Toxicol Pathol 2010 0.86
50 Gentamicin extended release from an injectable polymeric implant. J Control Release 2006 0.86
51 Histopathology and apoptosis in an animal model of reversible renal injury. Exp Toxicol Pathol 2010 0.85
52 The effect of chronic progressive nephropathy on the incidence of renal tubule cell neoplasms in control male F344 rats. Toxicol Pathol 2003 0.85
53 Toxicity and carcinogenicity of the water disinfection byproduct, dibromoacetic acid, in rats and mice. Toxicology 2006 0.85
54 Early effects of iodine on DNA synthesis in sulfur mustard-induced skin lesions. Arch Toxicol 2006 0.84
55 Biomarkers of Oxidative Stress Study IV: ozone exposure of rats and its effect on antioxidants in plasma and bronchoalveolar lavage fluid. Free Radic Biol Med 2011 0.84
56 Occult cardiotoxicity--toxic effects on cardiac ischemic tolerance. Toxicol Pathol 2009 0.84
57 Safety and biodistribution profile of placental-derived mesenchymal stromal cells (PLX-PAD) following intramuscular delivery. Toxicol Pathol 2009 0.84
58 Intratumoral delivery of paclitaxel for treatment of orthotopic prostate cancer. J Pharm Sci 2009 0.84
59 Induction of thyroid lesions in 14-week toxicity studies of 2 and 4-methylimidazole in Fischer 344/N rats and B6C3F1 mice. Arch Toxicol 2005 0.84
60 Characterization of liver toxicity in F344/N rats and B6C3F1 mice after exposure to a flame retardant containing lower molecular weight polybrominated diphenyl ethers. Exp Toxicol Pathol 2008 0.84
61 Gastrointestinal hyperplasia with altered expression of DNA polymerase beta. PLoS One 2009 0.83
62 Immunohistochemical analysis of expressions of hepatic cytochrome P450 in F344 rats following oral treatment with kava extract. Exp Toxicol Pathol 2006 0.83
63 Mechanisms of exocrine pancreatic toxicity induced by oral treatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin in female Harlan Sprague-Dawley Rats. Toxicol Sci 2005 0.83
64 Systemic imbalance of essential metals and cardiac gene expression in rats following acute pulmonary zinc exposure. J Toxicol Environ Health A 2006 0.83
65 Involvement of tumor necrosis factor-alpha in sulfur mustard-induced skin lesion; effect of topical iodine. Arch Toxicol 2005 0.83
66 Characterization of bronchiolar metaplasia of the alveolar epithelium in female Sprague-Dawley rats exposed to 3,3',4,4',5-pentachlorobiphenyl (PCB126). Toxicol Pathol 2004 0.83
67 Enhancing pigmentation via activation of A3 adenosine receptors in B16 melanoma cells and in human skin explants. Exp Dermatol 2012 0.83
68 Proceedings of the 2011 National Toxicology Program Satellite Symposium. Toxicol Pathol 2011 0.82
69 Regulated over-expression of DNA polymerase beta mediates early onset cataract in mice. DNA Repair (Amst) 2003 0.82
70 Reproductive lesions in female Harlan Sprague-Dawley rats following two-year oral treatment with dioxin and dioxin-like compounds. Toxicol Pathol 2009 0.82
71 Hepatocellular carcinomas in B6C3F1 mice treated with Ginkgo biloba extract for two years differ from spontaneous liver tumors in cancer gene mutations and genomic pathways. Toxicol Pathol 2012 0.82
72 Biocompatibility and safety evaluation of a ricinoleic acid-based poly(ester-anhydride) copolymer after implantation in rats. J Biomed Mater Res A 2010 0.82
73 Protective effect of topical iodine containing anti-inflammatory drugs against sulfur mustard-induced skin lesions. Arch Toxicol 2003 0.82
74 Dietary salt exacerbates isoproterenol-induced cardiomyopathy in rats. Toxicol Pathol 2011 0.81
75 Particulate matter inhalation exacerbates cardiopulmonary injury in a rat model of isoproterenol-induced cardiomyopathy. Inhal Toxicol 2010 0.81
76 Carcinogenic mode of action of folpet in mice and evaluation of its relevance to humans. Crit Rev Toxicol 2010 0.81
77 Myocardial mitochondrial injury induced by pulmonary exposure to particulate matter in rats. Toxicol Pathol 2012 0.81
78 Toxicity and carcinogenicity of Elmiron in F344/N rats and B6C3F1 mice following 2 years of gavage administration. Arch Toxicol 2003 0.81
79 Anti-HER2 cationic immunoemulsion as a potential targeted drug delivery system for the treatment of prostate cancer. Cancer Res 2007 0.81
80 Alteration in regulation of inflammatory response to influenza a virus and endotoxin in suckling rat pups: a potential relationship to sudden infant death syndrome. FEMS Immunol Med Microbiol 2004 0.81
81 Treatment of osteomyelitis in rats by injection of degradable polymer releasing gentamicin. J Control Release 2008 0.81
82 Adrenergic differentiation and Ret expression in rat pheochromocytomas. Endocr Pathol 2008 0.81
83 Induction of interleukin-1beta, tumour necrosis factor-alpha and apoptosis in mouse organs by amphotericin B is neutralized by conjugation with arabinogalactan. J Antimicrob Chemother 2005 0.81
84 Comparison of chronic toxicity and carcinogenicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in 2-year bioassays in female Sprague-Dawley rats. Mol Nutr Food Res 2006 0.81
85 The toxicity and pathology of selected dietary herbal medicines. Toxicol Pathol 2012 0.81
86 Pulmonary thrombosis in the mouse following intravenous administration of quantum dot-labeled mesenchymal cells. Nanotoxicology 2010 0.81
87 A chemically induced rat model of hemolysis with disseminated thrombosis. Cardiovasc Toxicol 2002 0.80
88 A comparative immunohistochemical study of spontaneous and chemically induced pheochromocytomas in B6C3F1 mice. Endocr Pathol 2003 0.80
89 Subchronic pulmonary pathology, iron overload, and transcriptional activity after Libby amphibole exposure in rat models of cardiovascular disease. Environ Health Perspect 2011 0.80
90 Epididymal sperm granuloma induced by chronic administration of 2-methylimidazole in B6C3F1 mice. Toxicol Pathol 2005 0.80
91 Testosterone deficiency accompanied by testicular and epididymal abnormalities in TMF(-/-) mice. Mol Cell Endocrinol 2012 0.80
92 Follicular epithelial cell hypertrophy induced by chronic oral administration of 2,3,7,8-tetrachlorodibenzo-p-dioxin in female Harlan Sprague-Dawley rats. Toxicol Pathol 2004 0.80
93 Characterization of spontaneous and chemically induced cardiac lesions in rodent model systems: the national toxicology program experience. Cardiovasc Toxicol 2005 0.80
94 Evidence for infection, inflammation and shock in sudden infant death: parallels between a neonatal rat model of sudden death and infants who died of sudden infant death syndrome. Innate Immun 2008 0.80
95 Pulmonary lesions in female Harlan Sprague-Dawley rats following two-year oral treatment with dioxin-like compounds. Toxicol Pathol 2007 0.80
96 Pulmonary inflammatory and fibrotic responses in Fischer 344 rats after intratracheal instillation exposure to Libby amphibole. J Toxicol Environ Health A 2011 0.79
97 Systemic vascular disease in male B6C3F1 mice exposed to particulate matter by inhalation: studies conducted by the National Toxicology Program. Toxicol Pathol 2002 0.79
98 Spontaneous aortitis in the Balb/c mouse. Toxicol Pathol 2009 0.79
99 Comparative phenotypic assessment of cardiac pathology, physiology, and gene expression in C3H/HeJ, C57BL/6J, and B6C3F1/J mice. Toxicol Pathol 2010 0.79
100 Sumas Mountain chrysotile induces greater lung fibrosis in Fischer344 rats than Libby amphibole, El Dorado tremolite, and Ontario ferroactinolite. Toxicol Sci 2012 0.79
101 Immunohistochemical features of 3,3',4,4'-tetrachloroazobenzene-induced rat gingival lesions. Toxicol Pathol 2012 0.79
102 Amelioration of experimental autoimmune encephalitis by novel peptides: involvement of T regulatory cells. J Autoimmun 2010 0.79
103 Diesel exhaust induced pulmonary and cardiovascular impairment: the role of hypertension intervention. Toxicol Appl Pharmacol 2013 0.79
104 Association of adrenal pheochromocytoma and lung pathology in inhalation studies with particulate compounds in the male F344 rat--the National Toxicology Program experience. Toxicol Pathol 2002 0.79
105 Liver toxicity and carcinogenicity in F344/N rats and B6C3F1 mice exposed to Kava Kava. Food Chem Toxicol 2011 0.79
106 The role of cardiovascular disease-associated iron overload in Libby amphibole-induced acute pulmonary injury and inflammation. Inhal Toxicol 2011 0.78
107 A natural antioxidant mixture from spinach does not have estrogenic or antiestrogenic activity in immature CD-1 mice. J Nutr 2003 0.78
108 The influence of fasting on blood glucose, triglycerides, cholesterol, and alkaline phosphatase in rats. Vet Clin Pathol 1994 0.78
109 Chemical-induced atrial thrombosis in NTP rodent studies. Toxicol Pathol 2005 0.78
110 Composition, efficacy, and safety of spinach extracts. Nutr Cancer 2003 0.78
111 Acrylonitrile is a multisite carcinogen in male and female B6C3F1 mice. Toxicol Sci 2002 0.78
112 Subcutaneous and intraperitoneal lipogranulomas following subcutaneous injection of olive oil in Sprague-Dawley rats. Toxicol Pathol 2009 0.78
113 Morphologic aspects of rodent cardiotoxicity in a retrospective evaluation of National Toxicology Program studies. Toxicol Pathol 2011 0.78
114 Inflammatory and chloracne-like skin lesions in B6C3F1 mice exposed to 3,3',4,4'-tetrachloroazobenzene for 2 years. Toxicology 2009 0.78
115 Assessment of the safety and biodistribution of a regulated AAV2 gene transfer vector after delivery to murine submandibular glands. Toxicol Sci 2011 0.78
116 Thyroid follicular lesions induced by oral treatment for 2 years with 2,3,7,8-tetrachlorodibenzo-p-dioxin and dioxin-like compounds in female Harlan Sprague-Dawley rats. Toxicol Pathol 2010 0.78
117 Gene expression profiling of rat pheochromocytoma. Ann N Y Acad Sci 2006 0.78
118 Aging and susceptibility to toluene in rats: a pharmacokinetic, biomarker, and physiological approach. J Toxicol Environ Health A 2010 0.78
119 Comparative long-term toxicity of Libby amphibole and amosite asbestos in rats after single or multiple intratracheal exposures. J Toxicol Environ Health A 2015 0.78
120 Cardiac damage in rodents after exposure to bis(2-chloroethoxy)methane. Toxicol Pathol 2004 0.78
121 Carrier free rapamycin loaded drug eluting stent: in vitro and in vivo evaluation. J Control Release 2013 0.77
122 Cardiopulmonary responses of Wistar Kyoto, spontaneously hypertensive, and stroke-prone spontaneously hypertensive rats to particulate matter (PM) exposure. J Toxicol Environ Health A 2007 0.77
123 Age and dose sensitivities in the 2-butoxyethanol F344 rat model of hemolytic anemia and disseminated thrombosis. Exp Toxicol Pathol 2007 0.77
124 2-Butoxyethanol enhances the adherence of red blood cells. Arch Toxicol 2003 0.77
125 Disseminated thrombosis-induced growth plate necrosis in rat: a unique model for growth plate arrest. J Pediatr Orthop 2005 0.77
126 Drug-induced thrombosis: an update. Drug Saf 2013 0.76
127 Multisite carcinogenicity and respiratory toxicity of inhaled 1-bromopropane in rats and mice. Toxicol Pathol 2011 0.76
128 A novel nanocapsule delivery system to overcome intestinal degradation and drug transport limited absorption of P-glycoprotein substrate drugs. Pharm Res 2008 0.76
129 Vitamin A deficiency aggravates rotavirus infection in CD-1 mice through extensive involvement of the gut. Int J Vitam Nutr Res 2004 0.76
130 Hemostatic activation in a chemically induced rat model of severe hemolysis and thrombosis. Thromb Res 2006 0.76
131 Ischemic brain damage after ketamine and xylazine treatment in a young laboratory monkey (Macaca fascicularis). Contemp Top Lab Anim Sci 2005 0.76
132 Evaluation of glycosaminoglycans content and 5-hydroxytryptamine 2B receptor in the heart valves of Sprague-Dawley rats with spontaneous mitral valvulopathy--a possible exacerbation by dl-amphetamine sulfate in Fischer 344 rats? Exp Toxicol Pathol 2006 0.76
133 Occult cardiotoxicity: subtoxic dosage of Bis(2-chloroethoxy)methane impairs cardiac response to simulated ischemic injury. Toxicol Pathol 2007 0.76
134 Bis(2-chloroethoxy)methane-induced mitochondrial and myofibrillar damage: short-term time-course study. Toxicol Sci 2004 0.76
135 Protective effect of topical iodine preparations upon heat-induced and hydrofluoric acid-induced skin lesions. Toxicol Pathol 2002 0.76
136 Hexachlorobenzene-induced incisor degeneration in Sprague-Dawley rats. Toxicol Pathol 2004 0.75
137 Intestinal lymphangiectasis and lipidosis in rats following subchronic exposure to indole-3-carbinol via oral gavage. Toxicol Pathol 2012 0.75
138 Computed tomography of Lipiodol-loaded biodegradable pasty polymer for implant visualization. Contrast Media Mol Imaging 2014 0.75
139 Repeated dose toxicity and relative potency of 1,2,3,4,6,7-hexachloronaphthalene (PCN 66) 1,2,3,5,6,7-hexachloronaphthalene (PCN 67) compared to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) for induction of CYP1A1, CYP1A2 and thymic atrophy in female Harlan Sprague-Dawley rats. Toxicology 2012 0.75
140 Letter to the editor. Toxicol Pathol 2010 0.75
141 Investigating the potential for toxicity from long-term use of the herbal products, goldenseal and milk thistle. Toxicol Pathol 2011 0.75
142 Spontaneous glomerulonephritis in Göttingen minipigs. Toxicol Pathol 2011 0.75
143 2-Butoxyethanol female-rat model of hemolysis and disseminated thrombosis: X-ray characterization of osteonecrosis and growth-plate suppression. Toxicol Pathol 2005 0.75
144 Forestomach tumor induction by 2,4-hexadienal in F344N rats and B6C3F1 mice. Arch Toxicol 2003 0.75
145 Application of a statistical dynamic model investigating the short-term cellular kinetics induced by riddelliine, a hepatic endothelial carcinogen. Toxicol Sci 2004 0.75
146 Does terbutaline damage the developing heart? Birth Defects Res B Dev Reprod Toxicol 2003 0.75
147 Foreign-body granulomas within intramyocardial arteries in a transcoronary safety assessment in pigs. Toxicol Pathol 2008 0.75