1
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Mannose-binding lectin variant alleles and the risk of arterial thrombosis in systemic lupus erythematosus.
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N Engl J Med
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2004
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2.62
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2
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Genetically determined high serum levels of mannose-binding lectin and agalactosyl IgG are associated with ischemic heart disease in rheumatoid arthritis.
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Arthritis Rheum
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2007
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1.70
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3
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Mannose-binding lectin engagement with late apoptotic and necrotic cells.
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Eur J Immunol
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2003
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1.66
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4
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Human genetic deficiencies reveal the roles of complement in the inflammatory network: lessons from nature.
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Proc Natl Acad Sci U S A
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2009
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1.53
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5
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Polymorphisms in the FCN2 gene determine serum variation and function of Ficolin-2.
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Hum Mol Genet
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2005
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1.50
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6
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Complement plays a central role in Candida albicans-induced cytokine production by human PBMCs.
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Eur J Immunol
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2012
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1.50
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7
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Mannose-binding lectin variant alleles and HLA-DR4 alleles are associated with giant cell arteritis.
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J Rheumatol
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2002
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1.48
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8
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Low mannose-binding lectin serum levels are associated with reduced kidney graft survival.
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Kidney Int
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2012
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1.48
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9
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Mortality and predictors of mortality in rheumatoid arthritis--a role for mannose-binding lectin?
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J Rheumatol
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2010
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1.46
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10
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Multiple inflammatory markers in patients with significant coronary artery disease.
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Int J Cardiol
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2006
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1.45
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11
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Disease-associated mutations in human mannose-binding lectin compromise oligomerization and activity of the final protein.
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J Biol Chem
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2004
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1.40
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12
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A common polymorphism in the SFTPD gene influences assembly, function, and concentration of surfactant protein D.
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J Immunol
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2005
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1.36
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13
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Strong combined gene-environment effects in anti-cyclic citrullinated peptide-positive rheumatoid arthritis: a nationwide case-control study in Denmark.
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Arthritis Rheum
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2007
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1.36
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14
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Mannose-binding lectin polymorphisms in clinical tuberculosis.
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J Infect Dis
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2003
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1.32
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15
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Synergy between ficolin-2 and pentraxin 3 boosts innate immune recognition and complement deposition.
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J Biol Chem
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1.29
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16
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Immunodeficiency associated with FCN3 mutation and ficolin-3 deficiency.
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N Engl J Med
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2009
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1.24
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17
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Characterization of a polymorphism in the coding sequence of FCN3 resulting in a Ficolin-3 (Hakata antigen) deficiency state.
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Mol Immunol
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2008
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1.23
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18
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Ficolin-2 recognizes DNA and participates in the clearance of dying host cells.
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Mol Immunol
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2006
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1.23
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19
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A novel mannose-binding lectin/ficolin-associated protein is highly expressed in heart and skeletal muscle tissues and inhibits complement activation.
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J Biol Chem
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2010
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1.23
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20
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Comparative study of the human ficolins reveals unique features of Ficolin-3 (Hakata antigen).
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Mol Immunol
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2007
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1.19
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21
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The innate pattern recognition molecule Ficolin-1 is secreted by monocytes/macrophages and is circulating in human plasma.
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Mol Immunol
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2008
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1.18
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22
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Extra-hepatic transcription of the human mannose-binding lectin gene (mbl2) and the MBL-associated serine protease 1-3 genes.
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Mol Immunol
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2005
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1.18
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23
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Antibody-mediated activation of the classical pathway of complement may compensate for mannose-binding lectin deficiency.
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Eur J Immunol
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2004
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1.15
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24
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Deficiency of somatic hypermutation of the antibody light chain is associated with increased frequency of severe respiratory tract infection in common variable immunodeficiency.
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Blood
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2004
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1.13
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25
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Functional SNPs in the human ficolin (FCN) genes reveal distinct geographical patterns.
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Mol Immunol
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2008
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1.13
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26
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Variant mannose-binding lectin alleles are not associated with susceptibility to or outcome of invasive pneumococcal infection in randomly included patients.
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J Infect Dis
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2002
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1.13
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27
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Mini-review: A pivotal role for innate immunity in the clearance of apoptotic cells.
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Eur J Immunol
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1.11
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28
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Molecular organization of human Ficolin-2.
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Mol Immunol
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2006
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1.11
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29
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The non-phagocytic route of collagen uptake: a distinct degradation pathway.
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J Biol Chem
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1.09
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30
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Pentraxin-3 serum levels are associated with disease severity and mortality in patients with systemic inflammatory response syndrome.
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PLoS One
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1.08
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31
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Influence of candidate susceptibility genes on tuberculosis in a high endemic region.
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Mol Immunol
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2006
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1.08
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32
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A metalloproteinase karilysin present in the majority of Tannerella forsythia isolates inhibits all pathways of the complement system.
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J Immunol
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2012
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1.07
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33
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The innate immune component ficolin 3 (Hakata antigen) mediates the clearance of late apoptotic cells.
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Arthritis Rheum
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2007
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1.05
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34
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Natural resistance-associated macrophage protein 1 polymorphisms are associated with microscopy-positive tuberculosis.
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J Infect Dis
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2002
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1.03
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35
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Association of Chlamydia pneumoniae with coronary artery disease and its progression is dependent on the modifying effect of mannose-binding lectin.
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Circulation
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2002
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1.03
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36
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Staphylococcal proteases aid in evasion of the human complement system.
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J Innate Immun
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1.02
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37
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Interactions of the humoral pattern recognition molecule PTX3 with the complement system.
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Immunobiology
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1.02
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38
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Association of HMGB1 polymorphisms with outcome in patients with systemic inflammatory response syndrome.
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Crit Care
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2008
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1.00
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39
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Association of HMGB1 polymorphisms with outcome after allogeneic hematopoietic cell transplantation.
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Biol Blood Marrow Transplant
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2009
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0.99
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40
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Complement-mediated neutralization of dengue virus requires mannose-binding lectin.
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MBio
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0.97
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41
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Ficolin-1 is present in a highly mobilizable subset of human neutrophil granules and associates with the cell surface after stimulation with fMLP.
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J Leukoc Biol
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2009
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0.97
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42
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Ficolin-1-PTX3 complex formation promotes clearance of altered self-cells and modulates IL-8 production.
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J Immunol
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0.97
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43
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Collectin-11/MASP complex formation triggers activation of the lectin complement pathway--the fifth lectin pathway initiation complex.
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J Innate Immun
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0.96
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44
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Functional analysis of Ficolin-3 mediated complement activation.
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PLoS One
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Heterocomplexes of mannose-binding lectin and the pentraxins PTX3 or serum amyloid P component trigger cross-activation of the complement system.
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J Biol Chem
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0.96
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46
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Heterozygosity of mannose-binding lectin (MBL2) genotypes predicts advantage (heterosis) in relation to fatal outcome in intensive care patients.
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Hum Mol Genet
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2007
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0.95
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47
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Association between combined properdin and mannose-binding lectin deficiency and infection with Neisseria meningitidis.
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Mol Immunol
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2005
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0.95
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48
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N965S is a common ABCA4 variant in Stargardt-related retinopathies in the Danish population.
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Mol Vis
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2007
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0.94
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49
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Serum levels of ficolin-3 (Hakata antigen) in patients with systemic lupus erythematosus.
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J Rheumatol
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0.93
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50
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Early rise of anti-pseudomonas antibodies and a mucoid phenotype of pseudomonas aeruginosa are risk factors for development of chronic lung infection--a case control study.
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J Cyst Fibros
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2006
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0.92
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51
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The 'involution' of mannose-binding lectin.
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Hum Mol Genet
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2005
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0.92
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52
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Endogenous and natural complement inhibitor attenuates myocardial injury and arterial thrombogenesis.
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Circulation
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2012
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0.92
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53
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High rate of early restenosis after carotid eversion endarterectomy in homozygous carriers of the normal mannose-binding lectin genotype.
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Stroke
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2005
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0.92
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54
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Tethering of Ficolin-1 to cell surfaces through recognition of sialic acid by the fibrinogen-like domain.
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J Leukoc Biol
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2010
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0.91
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55
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Double role of mannose-binding lectin in relation to carotid intima-media thickness in patients with rheumatoid arthritis.
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Mol Immunol
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2009
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0.90
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56
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Properdin deficiency associated with recurrent otitis media and pneumonia, and identification of male carrier with Klinefelter syndrome.
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Clin Immunol
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2009
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0.90
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57
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The down-stream effects of mannan-induced lectin complement pathway activation depend quantitatively on alternative pathway amplification.
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Mol Immunol
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2009
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0.90
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58
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Immunosuppression and risk of cervical cancer.
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Expert Rev Anticancer Ther
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2013
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0.89
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59
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Strong complement activation after acute ischemic stroke is associated with unfavorable outcomes.
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Atherosclerosis
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2008
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0.89
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60
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Mannose-binding lectin deficiency is associated with myocardial infarction: the HUNT2 study in Norway.
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PLoS One
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0.89
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61
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Genetically determined serum levels of mannose-binding lectin correlate negatively with common carotid intima-media thickness in systemic lupus erythematosus.
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J Rheumatol
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2010
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0.88
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62
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Low ficolin-3 levels in early follow-up serum samples are associated with the severity and unfavorable outcome of acute ischemic stroke.
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J Neuroinflammation
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0.88
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63
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The role of properdin in zymosan- and Escherichia coli-induced complement activation.
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J Immunol
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64
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MBL-associated serine protease-3 circulates in high serum concentrations predominantly in complex with Ficolin-3 and regulates Ficolin-3 mediated complement activation.
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Immunobiology
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0.87
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65
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Increased frequency of mannose-binding lectin insufficiency among children with acute lymphoblastic leukemia.
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Blood
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0.86
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66
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Ficolins and Mannose-Binding Lectin in Danish patients with sarcoidosis.
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Respir Med
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67
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The interaction pattern of murine serum ficolin-A with microorganisms.
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PLoS One
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68
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Low C4 gene copy numbers are associated with superior graft survival in patients transplanted with a deceased donor kidney.
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Kidney Int
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2013
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0.85
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69
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Ficolin-2 reveals different analytical and biological properties dependent on different sample handling procedures.
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Mol Immunol
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2013
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0.85
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70
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Elevated complement C3 is associated with early restenosis after eversion carotid endarterectomy.
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Thromb Haemost
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2006
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0.84
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71
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IgG glycosylation changes and MBL2 polymorphisms: associations with markers of systemic inflammation and joint destruction in rheumatoid arthritis.
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J Rheumatol
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0.84
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72
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Transcompartmental inflammatory responses in humans: IV versus endobronchial administration of endotoxin*.
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Crit Care Med
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73
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Plasma YKL-40 and CHI3L1 in systemic inflammation and sepsis-experience from two prospective cohorts.
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Immunobiology
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74
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Ficolin-3-mediated lectin complement pathway activation in patients with subarachnoid hemorrhage.
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Neurology
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2013
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0.83
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75
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C1q deficiency in an Inuit family: identification of a new class of C1q disease-causing mutations.
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Clin Immunol
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2007
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0.83
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76
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The prognostic value of YKL-40 concentrations in nonmyeloablative conditioning allogeneic hematopoietic cell transplantation.
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Biol Blood Marrow Transplant
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0.83
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77
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Serum concentration and interaction properties of MBL/ficolin associated protein-1.
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Immunobiology
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2010
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0.83
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78
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Degree of predicted minor histocompatibility antigen mismatch correlates with poorer clinical outcomes in nonmyeloablative allogeneic hematopoietic cell transplantation.
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Biol Blood Marrow Transplant
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2010
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0.83
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79
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Infections during induction therapy of childhood acute lymphoblastic leukemia--no association to mannose-binding lectin deficiency.
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Eur J Haematol
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2006
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0.82
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Genetic and other factors determining mannose-binding lectin levels in American Indians: the Strong Heart Study.
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BMC Med Genet
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0.82
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81
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Adenosine derived from Staphylococcus aureus-engulfed macrophages functions as a potent stimulant for the induction of inflammatory cytokines in mast cells.
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BMB Rep
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2011
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0.82
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82
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Mannose-binding lectin genotypes and susceptibility to epstein-barr virus infection in infancy.
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Clin Vaccine Immunol
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0.82
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83
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Mannose-binding lectin gene polymorphisms are associated with disease activity and physical disability in untreated, anti-cyclic citrullinated peptide-positive patients with early rheumatoid arthritis.
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J Rheumatol
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2009
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0.81
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84
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Association between mannose-binding lectin polymorphisms and Wuchereria bancrofti infection in two communities in North-Eastern Tanzania.
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Am J Trop Med Hyg
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2010
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0.81
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85
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Influence of Factor V Leiden on susceptibility to and outcome from critical illness: a genetic association study.
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Crit Care
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2010
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0.81
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86
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Mannose-binding lectin genotype as a risk factor for invasive pneumococcal infection.
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Lancet
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2002
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0.81
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87
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Mouse mannose-binding lectin-A and ficolin-A inhibit lipopolysaccharide-mediated pro-inflammatory responses on mast cells.
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BMB Rep
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2013
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0.81
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88
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Association between lectin complement pathway initiators, C-reactive protein and left ventricular remodeling in myocardial infarction-a magnetic resonance study.
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Mol Immunol
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Association of ficolin-3 with severity and outcome of chronic heart failure.
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PLoS One
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Low c1-inhibitor levels predict early restenosis after eversion carotid endarterectomy.
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Arterioscler Thromb Vasc Biol
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91
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Primary complement C5 deficiencies - molecular characterization and clinical review of two families.
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Immunobiology
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Risk of cervical cancer in women with autoimmune diseases, in relation with their use of immunosuppressants and screening: population-based cohort study.
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Genetic Susceptibility to Sepsis: A Possible Role for Mannose-binding Lectin.
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Pre-transplant levels of ficolin-3 are associated with kidney graft survival.
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The role of ficolins and MASPs in hereditary angioedema due to C1-inhibitor deficiency.
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Mol Immunol
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High levels of mannose-binding lectin are associated with lower pulse wave velocity in uraemic patients.
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BMC Nephrol
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Primary immunodeficiency: complex genetic disorders?
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Anti-glomerular basement membrane glomerulonephritis and thrombotic microangiopathy in first degree relatives: a case report.
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Early complement activation follows eversion carotid endarterectomy and correlates with the time of clamping of the carotid artery.
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Mol Immunol
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Crystal structure and functional characterization of the complement regulator mannose-binding lectin (MBL)/ficolin-associated protein-1 (MAP-1).
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Ficolins Promote Fungal Clearance in vivo and Modulate the Inflammatory Cytokine Response in Host Defense against Aspergillus fumigatus.
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Early rise in serum VEGF and PDGF levels predisposes patients with a normal MBL2 genotype to restenosis after eversion endarterectomy.
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The pattern recognition molecule ficolin-1 exhibits differential binding to lymphocyte subsets, providing a novel link between innate and adaptive immunity.
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The Lectin Pathway of Complement and Biocompatibility.
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Smoking and polymorphisms of genes encoding mannose-binding lectin and surfactant protein-D in patients with rheumatoid arthritis.
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The epidermal growth factor receptor is a regulator of epidermal complement component expression and complement activation.
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Allelic lineages of the ficolin genes (FCNs) are passed from ancestral to descendant primates.
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Mannose-binding lectin in respiratory syncytial virus infection.
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In Memoriam: A Tribute to Professor Niels Borregaard.
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A novel assay to quantitate MASP-2/ficolin-3 complexes in serum.
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