Published in Eur J Immunol on October 01, 2003
Identification of two distinct macrophage subsets with divergent effects causing either neurotoxicity or regeneration in the injured mouse spinal cord. J Neurosci (2009) 6.93
The importance of natural IgM: scavenger, protector and regulator. Nat Rev Immunol (2010) 2.23
The macrophage and the apoptotic cell: an innate immune interaction viewed simplistically? Immunology (2004) 1.69
IgM antibodies to apoptosis-associated determinants recruit C1q and enhance dendritic cell phagocytosis of apoptotic cells. J Immunol (2009) 1.62
Regulation of dendritic cells and macrophages by an anti-apoptotic cell natural antibody that suppresses TLR responses and inhibits inflammatory arthritis. J Immunol (2009) 1.39
Mannan binding lectin as an adjunct to risk assessment for myocardial infarction in individuals with enhanced risk. J Exp Med (2004) 1.30
Oxidative stress and the regulation of complement activation in human glaucoma. Invest Ophthalmol Vis Sci (2010) 1.21
Adenovirus activates complement by distinctly different mechanisms in vitro and in vivo: indirect complement activation by virions in vivo. J Virol (2009) 1.18
Properdin: New roles in pattern recognition and target clearance. Mol Immunol (2008) 1.16
Deficiency of mannose-binding lectin greatly increases susceptibility to postburn infection with Pseudomonas aeruginosa. J Immunol (2006) 1.11
Protective role of the lung collectins surfactant protein A and surfactant protein D in airway inflammation. J Allergy Clin Immunol (2008) 1.10
Self and nonself recognition through C-type lectin receptor, Mincle. Self Nonself (2010) 1.08
Molecular MRI of acute necrosis with a novel DNA-binding gadolinium chelate: kinetics of cell death and clearance in infarcted myocardium. Circ Cardiovasc Imaging (2011) 1.07
Complement classical pathway components are all important in clearance of apoptotic and secondary necrotic cells. Clin Exp Immunol (2009) 1.07
Differential deposition of C4d and MBL in glomeruli of patients with ANCA-negative pauci-immune crescentic glomerulonephritis. J Clin Immunol (2009) 1.03
STAT6⁻/⁻ mice exhibit decreased cells with alternatively activated macrophage phenotypes and enhanced disease severity in murine neurocysticercosis. J Neuroimmunol (2010) 1.02
Activated complement components and complement activator molecules on the surface of cell-derived microparticles in patients with rheumatoid arthritis and healthy individuals. Ann Rheum Dis (2007) 1.01
Relative roles of complement factor 3 and mannose-binding lectin in host defense against infection. Infect Immun (2005) 0.95
C1q- and collectin-dependent phagocytosis of apoptotic host cells by the intestinal protozoan Entamoeba histolytica. J Infect Dis (2008) 0.93
High glucose disrupts oligosaccharide recognition function via competitive inhibition: a potential mechanism for immune dysregulation in diabetes mellitus. Immunobiology (2010) 0.93
Annexin-II, DNA, and histones serve as factor H ligands on the surface of apoptotic cells. J Biol Chem (2009) 0.92
The role of humoral innate immunity in hepatitis C virus infection. Viruses (2012) 0.91
C4b-binding protein binds to necrotic cells and DNA, limiting DNA release and inhibiting complement activation. J Exp Med (2005) 0.91
SIGN-R1, a C-type lectin, enhances apoptotic cell clearance through the complement deposition pathway by interacting with C1q in the spleen. Cell Death Differ (2012) 0.89
Mannan-binding lectin and complement C4A in Icelandic multicase families with systemic lupus erythematosus. Ann Rheum Dis (2006) 0.86
Mannose-binding lectin 2 polymorphisms do not influence frequency or type of infection in adults with chemotherapy induced neutropaenia. PLoS One (2012) 0.85
Cytochemical study of role of alpha-d-mannose- and beta-d-galactose-containing glycoproteins in apoptosis. J Mol Histol (2004) 0.84
C-reactive protein does not opsonize early apoptotic human neutrophils, but binds only membrane-permeable late apoptotic cells and has no effect on their phagocytosis by macrophages. J Inflamm (Lond) (2005) 0.84
Genotypes coding for low serum levels of mannose-binding lectin are underrepresented among individuals suffering from noninfectious systemic inflammatory response syndrome. Clin Vaccine Immunol (2009) 0.84
Mannose-binding lectin without the aid of its associated serine proteases alters lipopolysaccharide-mediated cytokine/chemokine secretion from human endothelial cells. Immunology (2007) 0.83
Complement protein C1q promotes macrophage anti-inflammatory M2-like polarization during the clearance of atherogenic lipoproteins. Inflamm Res (2014) 0.82
Clinical significance of macrophage phenotypes in cardiovascular disease. Clin Transl Med (2014) 0.82
Bridging effect of recombinant human mannose-binding lectin in macrophage phagocytosis of Escherichia coli. Immunology (2008) 0.81
Natural and adaptive IgM antibodies in the recognition of tumor-associated antigens of breast cancer (Review). Oncol Rep (2015) 0.81
Mannan-binding lectin in cardiovascular disease. Biomed Res Int (2014) 0.81
Oxidative stress decreases functional airway mannose binding lectin in COPD. PLoS One (2014) 0.80
Mannose-binding lectin 2 gene and risk of adult glioma. PLoS One (2013) 0.80
Association of ficolin-3 with severity and outcome of chronic heart failure. PLoS One (2013) 0.80
Serum Proteome Profiles in Stricturing Crohn's Disease: A Pilot Study. Inflamm Bowel Dis (2015) 0.80
Mannose-Binding Lectin Levels and Carotid Intima-Media Thickness in Type 2 Diabetic Patients. J Diabetes Res (2015) 0.80
Mannose-binding lectin and maladies of the bowel and liver. World J Gastroenterol (2006) 0.79
Complement system in lung disease. Am J Respir Cell Mol Biol (2014) 0.78
The effect of weight loss on serum mannose-binding lectin levels. Clin Dev Immunol (2012) 0.78
Absence of FcγRIII results in increased proinflammatory response in FcγRIII-KO cardiac recipients. Transplantation (2013) 0.78
Increased plasma mannose binding lectin levels are associated with bronchiolitis obliterans after lung transplantation. Respir Res (2012) 0.78
Mannose-binding lectin codon 54 genetic polymorphism and vaginal protein levels in women with gynecologic malignancies. Eur J Obstet Gynecol Reprod Biol (2012) 0.78
Identification of mammary epithelial cells subject to chronic oxidative stress in mammary epithelium of young women and teenagers living in USA: implication for breast carcinogenesis. Cancer Biol Ther (2012) 0.78
Activity of mannose-binding lectin in centenarians. Aging Cell (2012) 0.78
Effects of mannose-binding lectin on pulmonary gene expression and innate immune inflammatory response to ozone. Am J Physiol Lung Cell Mol Physiol (2016) 0.77
Mannose-binding lectin (MBL) as prognostic factor in paediatric oncology patients. Clin Exp Immunol (2011) 0.77
Mannose-binding lectin gene variants and infections in patients receiving autologous stem cell transplantation. BMC Immunol (2014) 0.76
Comparative Analysis of Glycogene Expression in Different Mouse Tissues Using RNA-Seq Data. Int J Genomics (2014) 0.76
The presence of CD55- and/or CD59-deficient erythrocytic populations in patients with rheumatic diseases reflects an immune-mediated bone-marrow derived phenomenon. Med Sci Monit (2014) 0.75
Recombinant form of human wild type mannan-binding lectin (MBL/A) but not its structural variant (MBL/C) promotes phagocytosis of zymosan by activating complement. Mol Immunol (2010) 0.75
Low serum ficolin-3 levels are associated with severity and poor outcome in traumatic brain injury. J Neuroinflammation (2015) 0.75
Association Study of Mannose-Binding Lectin Levels and Genetic Variants in Lectin Pathway Proteins with Susceptibility to Age-Related Macular Degeneration: A Case-Control Study. PLoS One (2015) 0.75
C1 Complex: An Adaptable Proteolytic Module for Complement and Non-Complement Functions. Front Immunol (2017) 0.75
Complement in Kidney Transplantation. Front Med (Lausanne) (2017) 0.75
Variation in interleukin 7 receptor alpha chain (IL7R) influences risk of multiple sclerosis. Nat Genet (2007) 4.22
Structures of complement component C3 provide insights into the function and evolution of immunity. Nature (2005) 4.01
Immune evasion by a staphylococcal complement inhibitor that acts on C3 convertases. Nat Immunol (2005) 2.82
Mannose-binding lectin variant alleles and the risk of arterial thrombosis in systemic lupus erythematosus. N Engl J Med (2004) 2.62
High-resolution melting analysis (HRMA): more than just sequence variant screening. Hum Mutat (2009) 2.59
Mannose-binding lectin deficiency--revisited. Mol Immunol (2003) 2.52
A high-density screen for linkage in multiple sclerosis. Am J Hum Genet (2005) 2.50
The inhibiting Fc receptor for IgG, FcγRIIB, is a modifier of autoimmune susceptibility. J Immunol (2011) 2.44
Mannose binding lectin gene polymorphisms confer a major risk for severe infections after liver transplantation. Gastroenterology (2005) 2.30
Lectin complement pathway gene profile of donor and recipient determine the risk of bacterial infections after orthotopic liver transplantation. Hepatology (2010) 2.25
Allergy is a protective factor against age-related macular degeneration. Invest Ophthalmol Vis Sci (2014) 2.09
Pros and cons for C4d as a biomarker. Kidney Int (2012) 2.03
Association of mannose-binding lectin polymorphisms with sepsis and fatal outcome, in patients with systemic inflammatory response syndrome. J Infect Dis (2003) 1.77
Glomerular activation of the lectin pathway of complement in IgA nephropathy is associated with more severe renal disease. J Am Soc Nephrol (2006) 1.72
Genetically determined high serum levels of mannose-binding lectin and agalactosyl IgG are associated with ischemic heart disease in rheumatoid arthritis. Arthritis Rheum (2007) 1.70
Secretory IgA N- and O-glycans provide a link between the innate and adaptive immune systems. J Biol Chem (2003) 1.68
Biochemical and functional characterization of the interaction between pentraxin 3 and C1q. Eur J Immunol (2003) 1.67
The complement system in systemic autoimmune disease. J Autoimmun (2009) 1.64
Opsonization with C1q and mannose-binding lectin targets apoptotic cells to dendritic cells. J Immunol (2004) 1.64
GWAS of follicular lymphoma reveals allelic heterogeneity at 6p21.32 and suggests shared genetic susceptibility with diffuse large B-cell lymphoma. PLoS Genet (2011) 1.58
Human genetic deficiencies reveal the roles of complement in the inflammatory network: lessons from nature. Proc Natl Acad Sci U S A (2009) 1.53
IL-10-producing macrophages preferentially clear early apoptotic cells. Blood (2006) 1.53
Direct binding of C1q to apoptotic cells and cell blebs induces complement activation. Eur J Immunol (2002) 1.52
Polymorphisms in the FCN2 gene determine serum variation and function of Ficolin-2. Hum Mol Genet (2005) 1.50
Complement plays a central role in Candida albicans-induced cytokine production by human PBMCs. Eur J Immunol (2012) 1.50
Mannose-binding lectin variant alleles and HLA-DR4 alleles are associated with giant cell arteritis. J Rheumatol (2002) 1.48
Low mannose-binding lectin serum levels are associated with reduced kidney graft survival. Kidney Int (2012) 1.48
Functional characterization of the lectin pathway of complement in human serum. Mol Immunol (2003) 1.48
Mortality and predictors of mortality in rheumatoid arthritis--a role for mannose-binding lectin? J Rheumatol (2010) 1.46
Multiple inflammatory markers in patients with significant coronary artery disease. Int J Cardiol (2006) 1.45
Properdin binds to late apoptotic and necrotic cells independently of C3b and regulates alternative pathway complement activation. J Immunol (2008) 1.44
Disease-associated mutations in human mannose-binding lectin compromise oligomerization and activity of the final protein. J Biol Chem (2004) 1.40
A common polymorphism in the SFTPD gene influences assembly, function, and concentration of surfactant protein D. J Immunol (2005) 1.36
Strong combined gene-environment effects in anti-cyclic citrullinated peptide-positive rheumatoid arthritis: a nationwide case-control study in Denmark. Arthritis Rheum (2007) 1.36
Structure and function of the long pentraxin PTX3 glycosidic moiety: fine-tuning of the interaction with C1q and complement activation. Biochemistry (2006) 1.32
Mannose-binding lectin polymorphisms in clinical tuberculosis. J Infect Dis (2003) 1.32
Anti-C1q autoantibodies deposit in glomeruli but are only pathogenic in combination with glomerular C1q-containing immune complexes. J Clin Invest (2004) 1.31
A functional variant in the CFI gene confers a high risk of age-related macular degeneration. Nat Genet (2013) 1.29
Synergy between ficolin-2 and pentraxin 3 boosts innate immune recognition and complement deposition. J Biol Chem (2009) 1.29
Precise quantification of minimal residual disease at day 29 allows identification of children with acute lymphoblastic leukemia and an excellent outcome. Blood (2002) 1.27
Factor B structure provides insights into activation of the central protease of the complement system. Nat Struct Mol Biol (2007) 1.27
HLA-A alleles and infectious mononucleosis suggest a critical role for cytotoxic T-cell response in EBV-related Hodgkin lymphoma. Proc Natl Acad Sci U S A (2010) 1.27
Rapamycin specifically interferes with GM-CSF signaling in human dendritic cells, leading to apoptosis via increased p27KIP1 expression. Blood (2002) 1.26
Myeloperoxidase is critically involved in the induction of organ damage after renal ischemia reperfusion. Am J Pathol (2007) 1.24
Immunodeficiency associated with FCN3 mutation and ficolin-3 deficiency. N Engl J Med (2009) 1.24
Characterization of a polymorphism in the coding sequence of FCN3 resulting in a Ficolin-3 (Hakata antigen) deficiency state. Mol Immunol (2008) 1.23
Ficolin-2 recognizes DNA and participates in the clearance of dying host cells. Mol Immunol (2006) 1.23
A novel mannose-binding lectin/ficolin-associated protein is highly expressed in heart and skeletal muscle tissues and inhibits complement activation. J Biol Chem (2010) 1.23
Association between larger thymic size and higher thymic output in human immunodeficiency virus-infected patients receiving highly active antiretroviral therapy. J Infect Dis (2002) 1.22
Complement activation by (auto-) antibodies. Mol Immunol (2011) 1.22
Expression and localization of lung surfactant protein A in human tissues. Am J Respir Cell Mol Biol (2003) 1.21
Mannose-binding lectin: clinical implications for infection, transplantation, and autoimmunity. Hum Immunol (2006) 1.20
Risk alleles in CFH and ARMS2 are independently associated with systemic complement activation in age-related macular degeneration. Ophthalmology (2011) 1.20
The membrane attack complex of complement induces caspase activation and apoptosis. Eur J Immunol (2002) 1.20
Maturation of dendritic cells abrogates C1q production in vivo and in vitro. Blood (2004) 1.20
Interactions of the extracellular matrix proteoglycans decorin and biglycan with C1q and collectins. J Immunol (2005) 1.19
Comparative study of the human ficolins reveals unique features of Ficolin-3 (Hakata antigen). Mol Immunol (2007) 1.19
The innate pattern recognition molecule Ficolin-1 is secreted by monocytes/macrophages and is circulating in human plasma. Mol Immunol (2008) 1.18
Extra-hepatic transcription of the human mannose-binding lectin gene (mbl2) and the MBL-associated serine protease 1-3 genes. Mol Immunol (2005) 1.18
Recognition and clearance of apoptotic cells: a role for complement and pentraxins. Trends Immunol (2003) 1.17
Connective tissue growth factor and igf-I are produced by human renal fibroblasts and cooperate in the induction of collagen production by high glucose. Diabetes (2003) 1.16
Antibody-mediated activation of the classical pathway of complement may compensate for mannose-binding lectin deficiency. Eur J Immunol (2004) 1.15
Human peritoneal macrophages show functional characteristics of M-CSF-driven anti-inflammatory type 2 macrophages. Eur J Immunol (2007) 1.14