Published in J Mol Biol on January 29, 2010
Structural Basis of a Key Factor Regulating the Affinity between the Zonula Occludens First PDZ Domain and Claudins. J Biol Chem (2015) 0.80
A binding site outside the canonical PDZ domain determines the specific interaction between Shank and SAPAP and their function. Proc Natl Acad Sci U S A (2016) 0.75
Affinity Enhancement by Ligand Clustering Effect Inspired by Peptide Dendrimers-Shank PDZ Proteins Interactions. PLoS One (2016) 0.75
Proteogenomic Analysis Identifies a Novel Human SHANK3 Isoform. Int J Mol Sci (2015) 0.75
Autistic-like social behaviour in Shank2-mutant mice improved by restoring NMDA receptor function. Nature (2012) 2.99
NGL family PSD-95-interacting adhesion molecules regulate excitatory synapse formation. Nat Neurosci (2006) 2.91
Excess of de novo deleterious mutations in genes associated with glutamatergic systems in nonsyndromic intellectual disability. Am J Hum Genet (2011) 2.86
Mutations in CHD7, encoding a chromatin-remodeling protein, cause idiopathic hypogonadotropic hypogonadism and Kallmann syndrome. Am J Hum Genet (2008) 2.33
Interaction between GRIP and liprin-alpha/SYD2 is required for AMPA receptor targeting. Neuron (2002) 2.05
GIT1 is associated with ADHD in humans and ADHD-like behaviors in mice. Nat Med (2011) 1.91
Trans-synaptic adhesion between NGL-3 and LAR regulates the formation of excitatory synapses. Nat Neurosci (2009) 1.83
Sequential activation of phosphatidylinositol 3-kinase, beta Pix, Rac1, and Nox1 in growth factor-induced production of H2O2. Mol Cell Biol (2004) 1.82
Biosynthesis, purification and characterization of silver nanoparticles using Escherichia coli. Colloids Surf B Biointerfaces (2009) 1.70
Regulation of dendritic spine morphogenesis by insulin receptor substrate 53, a downstream effector of Rac1 and Cdc42 small GTPases. J Neurosci (2005) 1.66
SALM synaptic cell adhesion-like molecules regulate the differentiation of excitatory synapses. Neuron (2006) 1.66
Antiangiogenic properties of silver nanoparticles. Biomaterials (2009) 1.55
The postsynaptic organization of synapses. Cold Spring Harb Perspect Biol (2011) 1.53
Role of the GYVG pore motif of HslU ATPase in protein unfolding and translocation for degradation by HslV peptidase. J Biol Chem (2005) 1.53
Association of the kinesin motor KIF1A with the multimodular protein liprin-alpha. J Biol Chem (2003) 1.53
Interaction between liprin-alpha and GIT1 is required for AMPA receptor targeting. J Neurosci (2003) 1.51
ERK-1/2 and p38 kinase oppositely regulate nitric oxide-induced apoptosis of chondrocytes in association with p53, caspase-3, and differentiation status. J Biol Chem (2001) 1.50
Interaction of the ERC family of RIM-binding proteins with the liprin-alpha family of multidomain proteins. J Biol Chem (2003) 1.47
FAK potentiates Rac1 activation and localization to matrix adhesion sites: a role for betaPIX. Mol Biol Cell (2006) 1.42
Dynamic regulation of cystic fibrosis transmembrane conductance regulator by competitive interactions of molecular adaptors. J Biol Chem (2007) 1.41
The C-terminal tails of HslU ATPase act as a molecular switch for activation of HslV peptidase. J Biol Chem (2002) 1.39
Maintenance of differentiated phenotype of articular chondrocytes by protein kinase C and extracellular signal-regulated protein kinase. J Biol Chem (2001) 1.38
The Shank family of postsynaptic density proteins interacts with and promotes synaptic accumulation of the beta PIX guanine nucleotide exchange factor for Rac1 and Cdc42. J Biol Chem (2003) 1.38
Ring-shaped architecture of RecR: implications for its role in homologous recombinational DNA repair. EMBO J (2004) 1.32
Negatively charged amino acids within the intraluminal loop of ryanodine receptor are involved in the interaction with triadin. J Biol Chem (2003) 1.32
An intramolecular interaction between the FHA domain and a coiled coil negatively regulates the kinesin motor KIF1A. EMBO J (2004) 1.30
Crystal structure of the Shank PDZ-ligand complex reveals a class I PDZ interaction and a novel PDZ-PDZ dimerization. J Biol Chem (2003) 1.29
Phosphorylation of stargazin by protein kinase A regulates its interaction with PSD-95. J Biol Chem (2002) 1.29
PI3Kγ is required for NMDA receptor-dependent long-term depression and behavioral flexibility. Nat Neurosci (2011) 1.28
The GIT family of proteins forms multimers and associates with the presynaptic cytomatrix protein Piccolo. J Biol Chem (2002) 1.28
Crystal structure of GRIP1 PDZ6-peptide complex reveals the structural basis for class II PDZ target recognition and PDZ domain-mediated multimerization. J Biol Chem (2002) 1.25
The NGL family of leucine-rich repeat-containing synaptic adhesion molecules. Mol Cell Neurosci (2009) 1.25
Slitrks control excitatory and inhibitory synapse formation with LAR receptor protein tyrosine phosphatases. Proc Natl Acad Sci U S A (2013) 1.22
Characterization of the movement of the kinesin motor KIF1A in living cultured neurons. J Biol Chem (2002) 1.21
Enhanced NMDA receptor-mediated synaptic transmission, enhanced long-term potentiation, and impaired learning and memory in mice lacking IRSp53. J Neurosci (2009) 1.21
A novel adipokine CTRP1 stimulates aldosterone production. FASEB J (2008) 1.20
Crystal structure of visfatin/pre-B cell colony-enhancing factor 1/nicotinamide phosphoribosyltransferase, free and in complex with the anti-cancer agent FK-866. J Mol Biol (2006) 1.19
Hydrophobic interface between two regulators of K+ conductance domains critical for calcium-dependent activation of large conductance Ca2+-activated K+ channels. J Biol Chem (2006) 1.18
De novo mutations in the motor domain of KIF1A cause cognitive impairment, spastic paraparesis, axonal neuropathy, and cerebellar atrophy. Hum Mutat (2014) 1.17
Silver nanoparticles inhibit VEGF induced cell proliferation and migration in bovine retinal endothelial cells. Colloids Surf B Biointerfaces (2009) 1.17
Phosphorylation of p85 beta PIX, a Rac/Cdc42-specific guanine nucleotide exchange factor, via the Ras/ERK/PAK2 pathway is required for basic fibroblast growth factor-induced neurite outgrowth. J Biol Chem (2002) 1.16
The active site of a lon protease from Methanococcus jannaschii distinctly differs from the canonical catalytic Dyad of Lon proteases. J Biol Chem (2004) 1.15
Structural and mechanistic insights into guanylylation of RNA-splicing ligase RtcB joining RNA between 3'-terminal phosphate and 5'-OH. Proc Natl Acad Sci U S A (2012) 1.14
Leucine-rich repeat proteins of synapses. J Neurosci Res (2007) 1.13
ARF6 and EFA6A regulate the development and maintenance of dendritic spines. J Neurosci (2006) 1.13
Regulation of synaptic Rac1 activity, long-term potentiation maintenance, and learning and memory by BCR and ABR Rac GTPase-activating proteins. J Neurosci (2010) 1.12
Esophageal cancer related gene 4 (ECRG4) is a marker of articular chondrocyte differentiation and cartilage destruction. Gene (2009) 1.11
Interaction of SPIN90 with the Arp2/3 complex mediates lamellipodia and actin comet tail formation. J Biol Chem (2005) 1.10
Silver nanoparticles inhibit VEGF-and IL-1beta-induced vascular permeability via Src dependent pathway in porcine retinal endothelial cells. J Nanobiotechnology (2009) 1.10
Microtubule-associated protein tau is essential for long-term depression in the hippocampus. Philos Trans R Soc Lond B Biol Sci (2013) 1.10
Palladin interacts with SH3 domains of SPIN90 and Src and is required for Src-induced cytoskeletal remodeling. Exp Cell Res (2007) 1.09
Synaptic adhesion molecules and PSD-95. Prog Neurobiol (2007) 1.09
Adiponectin is a negative regulator of NK cell cytotoxicity. J Immunol (2006) 1.06
The integrin-coupled signaling adaptor p130Cas suppresses Smad3 function in transforming growth factor-beta signaling. Mol Biol Cell (2008) 1.05
Regulated RalBP1 binding to RalA and PSD-95 controls AMPA receptor endocytosis and LTD. PLoS Biol (2009) 1.05
The interaction of phospholipase C-beta3 with Shank2 regulates mGluR-mediated calcium signal. J Biol Chem (2005) 1.05
Structure of Osh3 reveals a conserved mode of phosphoinositide binding in oxysterol-binding proteins. Structure (2013) 1.05
The 31-kDa caspase-generated cleavage product of p130cas functions as a transcriptional repressor of E2A in apoptotic cells. J Biol Chem (2003) 1.04
Autism spectrum disorder causes, mechanisms, and treatments: focus on neuronal synapses. Front Mol Neurosci (2013) 1.04
Preso, a novel PSD-95-interacting FERM and PDZ domain protein that regulates dendritic spine morphogenesis. J Neurosci (2008) 1.03
The rickettsia surface cell antigen 4 applies mimicry to bind to and activate vinculin. J Biol Chem (2011) 1.03
N-terminal region of FKBP12 is essential for binding to the skeletal ryanodine receptor. J Biol Chem (2004) 1.02
Shank2 associates with and regulates Na+/H+ exchanger 3. J Biol Chem (2005) 1.01
Phosphorylation of Ser 21 in Fyn regulates its kinase activity, focal adhesion targeting, and is required for cell migration. J Cell Physiol (2011) 1.00
Synaptic removal of diacylglycerol by DGKzeta and PSD-95 regulates dendritic spine maintenance. EMBO J (2009) 0.98
Crystal structure of a cyanobacterial phytochrome response regulator. Protein Sci (2002) 0.98
Filamin B serves as a molecular scaffold for type I interferon-induced c-Jun NH2-terminal kinase signaling pathway. Mol Biol Cell (2008) 0.98
Nuclear translocation of CAM-associated protein activates transcription for long-term facilitation in Aplysia. Cell (2007) 0.97
A helix replacement mechanism directs metavinculin functions. PLoS One (2010) 0.97
Selected SALM (synaptic adhesion-like molecule) family proteins regulate synapse formation. J Neurosci (2010) 0.97
Correction of X-ray intensities from an HslV-HslU co-crystal containing lattice-translocation defects. Acta Crystallogr D Biol Crystallogr (2005) 0.97
Antagonistic regulation of myogenesis by two deubiquitinating enzymes, UBP45 and UBP69. Proc Natl Acad Sci U S A (2002) 0.97
SPIN90/WISH interacts with PSD-95 and regulates dendritic spinogenesis via an N-WASP-independent mechanism. EMBO J (2006) 0.96
Characterization of calumenin-SERCA2 interaction in mouse cardiac sarcoplasmic reticulum. J Biol Chem (2009) 0.96
Synapse formation regulated by protein tyrosine phosphatase receptor T through interaction with cell adhesion molecules and Fyn. EMBO J (2009) 0.95
Diacylglycerol kinases in the regulation of dendritic spines. J Neurochem (2009) 0.94
DGKι regulates presynaptic release during mGluR-dependent LTD. EMBO J (2010) 0.94
Characterization of PINK1 (PTEN-induced putative kinase 1) mutations associated with Parkinson disease in mammalian cells and Drosophila. J Biol Chem (2013) 0.94
Activation of p21-activated kinase 1 is required for lysophosphatidic acid-induced focal adhesion kinase phosphorylation and cell motility in human melanoma A2058 cells. Eur J Biochem (2004) 0.94
GluA1 phosphorylation at serine 831 in the lateral amygdala is required for fear renewal. Nat Neurosci (2013) 0.94
Crystal structure of quinolinic acid phosphoribosyltransferase from Helicobacter pylori. Proteins (2006) 0.93