Published in Anesthesiology on March 01, 2010
Rats exposed to isoflurane in utero during early gestation are behaviorally abnormal as adults. Anesthesiology (2011) 2.41
Early childhood general anaesthesia exposure and neurocognitive development. Br J Anaesth (2010) 1.67
Anaesthetic neurotoxicity and neuroplasticity: an expert group report and statement based on the BJA Salzburg Seminar. Br J Anaesth (2013) 1.26
Propofol neurotoxicity is mediated by p75 neurotrophin receptor activation. Anesthesiology (2012) 1.21
Early exposure to general anesthesia disturbs mitochondrial fission and fusion in the developing rat brain. Anesthesiology (2013) 1.11
Reelin, an extracellular matrix protein linked to early onset psychiatric diseases, drives postnatal development of the prefrontal cortex via GluN2B-NMDARs and the mTOR pathway. Mol Psychiatry (2013) 0.99
Endocrine and neurobehavioral abnormalities induced by propofol administered to neonatal rats. Anesthesiology (2014) 0.97
Isoflurane affects the cytoskeleton but not survival, proliferation, or synaptogenic properties of rat astrocytes in vitro. Br J Anaesth (2013) 0.96
General anesthetics in pediatric anesthesia: influences on the developing brain. Curr Drug Targets (2012) 0.96
Transient effects of anesthetics on dendritic spines and filopodia in the living mouse cortex. Anesthesiology (2011) 0.95
Anesthesia-induced developmental neurodegeneration: the role of neuronal organelles. Front Neurol (2012) 0.94
Isoflurane impairs the capacity of astrocytes to support neuronal development in a mouse dissociated coculture model. J Neurosurg Anesthesiol (2014) 0.93
Review: effects of anesthetics on brain circuit formation. J Neurosurg Anesthesiol (2014) 0.90
Neuropathological sequelae of developmental exposure to antiepileptic and anesthetic drugs. Front Neurol (2012) 0.90
Propofol-induced changes in neurotrophic signaling in the developing nervous system in vivo. PLoS One (2012) 0.88
Early exposure to volatile anesthetics impairs long-term associative learning and recognition memory. PLoS One (2014) 0.88
Mechanistic insights into neurotoxicity induced by anesthetics in the developing brain. Int J Mol Sci (2012) 0.87
Anesthetics interfere with axon guidance in developing mouse neocortical neurons in vitro via a γ-aminobutyric acid type A receptor mechanism. Anesthesiology (2013) 0.84
GABAergic control of critical developmental periods for anxiety- and depression-related behavior in mice. PLoS One (2012) 0.84
Isoflurane-induced inactivation of CREB through histone deacetylase 4 is responsible for cognitive impairment in developing brain. Neurobiol Dis (2016) 0.84
Anesthetics interfere with the polarization of developing cortical neurons. J Neurosurg Anesthesiol (2012) 0.83
Lasting impact of general anaesthesia on the brain: mechanisms and relevance. Nat Rev Neurosci (2016) 0.83
Anaesthetics-induced neurotoxicity in developing brain: an update on preclinical evidence. Brain Sci (2014) 0.82
Perioperative central nervous system injury in neonates. Br J Anaesth (2012) 0.81
Deciphering the role of docosahexaenoic acid in brain maturation and pathology with magnetic resonance imaging. Prostaglandins Leukot Essent Fatty Acids (2012) 0.81
General Anesthesia Causes Epigenetic Histone Modulation of c-Fos and Brain-derived Neurotrophic Factor, Target Genes Important for Neuronal Development in the Immature Rat Hippocampus. Anesthesiology (2016) 0.80
Surgery and anesthesia: healing the body but harming the brain? Anesth Analg (2011) 0.80
Molecular Mechanisms of Anesthetic Neurotoxicity: A Review of the Current Literature. J Neurosurg Anesthesiol (2016) 0.79
At the sharp end of spines: anesthetic effects on synaptic remodeling in the developing brain. Anesthesiology (2010) 0.79
Isoflurane reversibly destabilizes hippocampal dendritic spines by an actin-dependent mechanism. PLoS One (2014) 0.77
Inhibition of isoflurane-induced increase of cell-surface redistribution and activity of glutamate transporter type 3 by serine 465 sequence-specific peptides. Eur J Pharmacol (2011) 0.77
Repeated exposure to ketamine-xylazine during early development impairs motor learning-dependent dendritic spine plasticity in adulthood. Anesthesiology (2015) 0.77
Peri-pubertal exposure to testicular hormones organizes response to novel environments and social behaviour in adult male rats. Horm Behav (2015) 0.76
Midazolam anesthesia protects neuronal cells from oxidative stress-induced death via activation of the JNK-ERK pathway. Mol Med Rep (2016) 0.76
Neurodevelopmental implications of the general anesthesia in neonate and infants. Exp Neurol (2015) 0.76
Reprogramming of the infant brain by surgery with general anesthesia. Mayo Clin Proc (2012) 0.76
A holistic approach to anesthesia-induced neurotoxicity and its implications for future mechanistic studies. Neurotoxicol Teratol (2016) 0.76
Exposure to Sevoflurane Affects the Development of Parvalbumin Interneurons in the Main Olfactory Bulb in Mice. Front Neuroanat (2016) 0.75
Safety first, safety at early age: The quagmire of neurotoxicity in paediatric anaesthesia. Indian J Anaesth (2013) 0.75
Repeated brief isoflurane anesthesia during early postnatal development produces negligible changes on adult behavior in male mice. PLoS One (2017) 0.75
Good gas, bad gas: isoflurane, carbon monoxide, and which is which? Anesth Analg (2014) 0.75
Desflurane impairs outcome of organotypic hippocampal slices in an in vitro model of traumatic brain injury. Med Gas Res (2016) 0.75
Early anesthetic exposure and long-term cognitive impairment. World J Exp Med (2011) 0.75
Anesthesia for myelomeningocele surgery in fetus. Childs Nerv Syst (2017) 0.75
Isoflurane produces antidepressant effects and induces TrkB signaling in rodents. Sci Rep (2017) 0.75
Early postnatal exposure to isoflurane causes cognitive deficits and disrupts development of newborn hippocampal neurons via activation of the mTOR pathway. PLoS Biol (2017) 0.75
Dendritic spine formation and stabilization. Curr Opin Neurobiol (2009) 2.59
Ventral tegmental area GABA projections pause accumbal cholinergic interneurons to enhance associative learning. Nature (2012) 2.23
Risk assessment for respiratory complications in paediatric anaesthesia: a prospective cohort study. Lancet (2010) 2.11
Comparison of static end-expiratory and effective lung volumes for gas exchange in healthy and surfactant-depleted lungs. Anesthesiology (2013) 2.00
Should the use of modified Jackson Rees T-piece breathing system be abandoned in preschool children? Paediatr Anaesth (2007) 1.94
Structural plasticity upon learning: regulation and functions. Nat Rev Neurosci (2012) 1.88
A multiparameter panel method for outcome prediction following aneurysmal subarachnoid hemorrhage. Intensive Care Med (2009) 1.75
LTP promotes a selective long-term stabilization and clustering of dendritic spines. PLoS Biol (2008) 1.65
Calcium/calmodulin-dependent protein kinase II contributes to activity-dependent filopodia growth and spine formation. J Neurosci (2003) 1.64
Laryngeal mask airway is associated with an increased incidence of adverse respiratory events in children with recent upper respiratory tract infections. Anesthesiology (2007) 1.57
Polysialic acid-neural cell adhesion molecule in brain plasticity: from synapses to integration of new neurons. Brain Res Rev (2007) 1.57
Activity-dependent PSD formation and stabilization of newly formed spines in hippocampal slice cultures. Cereb Cortex (2007) 1.55
Developmental Stage-dependent persistent impact of propofol anesthesia on dendritic spines in the rat medial prefrontal cortex. Anesthesiology (2011) 1.55
The mammalian central nervous synaptic cleft contains a high density of periodically organized complexes. Proc Natl Acad Sci U S A (2005) 1.55
Midazolam as premedication: is the emperor naked or just half-dressed? Paediatr Anaesth (2005) 1.54
The mental retardation protein PAK3 contributes to synapse formation and plasticity in hippocampus. J Neurosci (2004) 1.54
Polysialylated neural cell adhesion molecule promotes remodeling and formation of hippocampal synapses. J Neurosci (2004) 1.53
PSD-95 promotes synaptogenesis and multiinnervated spine formation through nitric oxide signaling. J Cell Biol (2008) 1.43
Sevoflurane and desflurane protect cholinergic-induced bronchoconstriction of hyperreactive airways in rabbits. Can J Anaesth (2011) 1.42
Alpha2-adrenergic receptor activation regulates cortical interneuron migration. Eur J Neurosci (2012) 1.38
N-cadherin mediates plasticity-induced long-term spine stabilization. J Cell Biol (2010) 1.34
VEGF is a chemoattractant for FGF-2-stimulated neural progenitors. J Cell Biol (2003) 1.34
Regulation of GABAergic synapse formation and plasticity by GSK3beta-dependent phosphorylation of gephyrin. Proc Natl Acad Sci U S A (2010) 1.32
The role of nicotinic acetylcholine receptors in the mechanisms of anesthesia. Brain Res Bull (2002) 1.32
The p21-activated kinase 3 implicated in mental retardation regulates spine morphogenesis through a Cdc42-dependent pathway. J Biol Chem (2007) 1.32
Interactions between NEEP21, GRIP1 and GluR2 regulate sorting and recycling of the glutamate receptor subunit GluR2. EMBO J (2005) 1.31
Anesthetics rapidly promote synaptogenesis during a critical period of brain development. PLoS One (2009) 1.30
Acute differential modulation of synaptic transmission and cell survival during exposure to pulsed and continuous radiofrequency energy. J Pain (2003) 1.28
Influence of matrix metalloproteinase MMP-9 on dendritic spine morphology. J Cell Sci (2011) 1.27
Long-term rearrangements of hippocampal mossy fiber terminal connectivity in the adult regulated by experience. Neuron (2006) 1.26
Incidence and risk factors of perioperative respiratory adverse events in children undergoing elective surgery. Paediatr Anaesth (2004) 1.15
GABA regulates dendritic growth by stabilizing lamellipodia in newly generated interneurons of the olfactory bulb. J Neurosci (2006) 1.12
Sequential implication of the mental retardation proteins ARHGEF6 and PAK3 in spine morphogenesis. J Cell Sci (2006) 1.12
Management of antithrombotic therapies in patients scheduled for eye surgery. Eur J Anaesthesiol (2013) 1.11
Effect of annealing treatments on photoluminescence and charge storage mechanism in silicon-rich SiNx:H films. Nanoscale Res Lett (2011) 1.07
Effect of ion implantation energy for the synthesis of Ge nanocrystals in SiN films with HfO2/SiO2 stack tunnel dielectrics for memory application. Nanoscale Res Lett (2011) 1.05
Glial responses to neonatal hypoxic-ischemic injury in the rat cerebral cortex. Int J Dev Neurosci (2007) 1.05
Presynaptic remodeling contributes to activity-dependent synaptogenesis. J Neurosci (2003) 1.03
PSA-NCAM in postnatally generated immature neurons of the olfactory bulb: a crucial role in regulating p75 expression and cell survival. Development (2007) 1.03
Role of matrix metalloproteinases in apoptosis after transient focal cerebral ischemia in rats and mice. Eur J Neurosci (2005) 1.01
Activity-induced changes of spine morphology. Hippocampus (2002) 1.01
We can do it: the interplay of construal orientation and social comparisons under threat. J Pers Soc Psychol (2005) 1.01
Kinetics of procalcitonin, interleukin 6 and C-reactive protein after cardiopulmonary-bypass in children. Cardiol Young (2003) 1.01
Use of analgesic and sedative drugs in the NICU: integrating clinical trials and laboratory data. Pediatr Res (2010) 0.99
An ion transport-independent role for the cation-chloride cotransporter KCC2 in dendritic spinogenesis in vivo. Cereb Cortex (2012) 0.98
Remodeling of hippocampal synaptic networks by a brief anoxia-hypoglycemia. J Neurosci (2002) 0.98
Retracted Childhood maltreatment and methylation of the glucocorticoid receptor gene NR3C1 in bipolar disorder. Br J Psychiatry (2013) 0.97
Glutamate receptor changes associated with transient anoxia/hypoglycaemia in hippocampal slice cultures. Eur J Neurosci (2006) 0.97
Signaling mechanisms regulating synapse formation and function in mental retardation. Curr Opin Neurobiol (2010) 0.96
Ischemia-induced modifications in hippocampal CA1 stratum radiatum excitatory synapses. Hippocampus (2006) 0.95
Propofol anesthesia impairs the maturation and survival of adult-born hippocampal neurons. Anesthesiology (2013) 0.95
The endosomal protein NEEP21 regulates AMPA receptor-mediated synaptic transmission and plasticity in the hippocampus. Mol Cell Neurosci (2005) 0.95
Anesthesia and the developing brain: a way forward for clinical research. Paediatr Anaesth (2015) 0.95
Synaptic potentiation induces increased glial coverage of excitatory synapses in CA1 hippocampus. Hippocampus (2009) 0.94
Adverse effects of methylene blue on the central nervous system. Anesthesiology (2008) 0.94
Bilateral whisker trimming during early postnatal life impairs dendritic spine development in the mouse somatosensory barrel cortex. J Comp Neurol (2010) 0.91
Central nervous system functions of PAK protein family: from spine morphogenesis to mental retardation. Mol Neurobiol (2006) 0.91
Alteration of synaptic network dynamics by the intellectual disability protein PAK3. J Neurosci (2012) 0.90
Interleukin-6 promotes sprouting and functional recovery in lesioned organotypic hippocampal slice cultures. J Neurochem (2006) 0.90
The role of PSA-NCAM in adult neurogenesis. Adv Exp Med Biol (2010) 0.89
Methacholine and ovalbumin challenges assessed by forced oscillations and synchrotron lung imaging. Am J Respir Crit Care Med (2009) 0.89
Effects of pulmonary vascular pressures and flow on airway and parenchymal mechanics in isolated rat lungs. J Appl Physiol (1985) (2002) 0.88
Estradiol promotes spine growth and synapse formation without affecting pre-established networks. Hippocampus (2010) 0.86
Automatic effects of alcohol and aggressive cues on aggressive thoughts and behaviors. Pers Soc Psychol Bull (2010) 0.86
Deletion of glutamate dehydrogenase 1 (Glud1) in the central nervous system affects glutamate handling without altering synaptic transmission. J Neurochem (2012) 0.86
Neuronal-induced and glutamate-dependent activation of glial glutamate transporter function. J Neurochem (2002) 0.86
Effect of positive end-expiratory pressure on regional ventilation distribution during mechanical ventilation after surfactant depletion. Anesthesiology (2013) 0.86
Early postnatal migration and development of layer II pyramidal neurons in the rodent cingulate/retrosplenial cortex. Cereb Cortex (2011) 0.86
Effect of cardiopulmonary bypass and aortic clamping on functional residual capacity and ventilation distribution in children. J Thorac Cardiovasc Surg (2007) 0.86
Biosafety in ex vivo gene therapy and conditional ablation of lentivirally transduced hepatocytes in nonhuman primates. Mol Ther (2009) 0.85
Long-term plasticity in mouse sensorimotor circuits after rhythmic whisker stimulation. J Neurosci (2009) 0.85
Distinct, but compensatory roles of PAK1 and PAK3 in spine morphogenesis. Hippocampus (2008) 0.85
Fast nongenomic effects of steroids on synaptic transmission and role of endogenous neurosteroids in spinal pain pathways. J Mol Neurosci (2006) 0.84
Impact of propofol anaesthesia on cytokine expression profiles in the developing rat brain: a randomised placebo-controlled experimental in-vivo study. Eur J Anaesthesiol (2015) 0.84
Mechanical support availability in pediatric cardiac surgery: program size should not matter. Int J Cardiol (2007) 0.84
Pre-existing astrocytes form functional perisynaptic processes on neurons generated in the adult hippocampus. Brain Struct Funct (2014) 0.84
A role for atm in E-cadherin-mediated contact inhibition in epithelial cells. Breast Cancer Res Treat (2006) 0.83
Nitric oxide mediates local activity-dependent excitatory synapse development. Proc Natl Acad Sci U S A (2013) 0.83
Reversal of activity-mediated spine dynamics and learning impairment in a mouse model of Fragile X syndrome. Eur J Neurosci (2014) 0.83
Electrophysiological characterization of tomato hypocotyl putative action potentials induced by cotyledon heating. Physiol Plant (2002) 0.83
Excitatory synaptic activity is associated with a rapid structural plasticity of inhibitory synapses on hippocampal CA1 pyramidal cells. Neuropharmacology (2010) 0.83
Differential roles of endothelin-1 ETA and ETB receptors and vasoactive intestinal polypeptide in regulation of the airways and the pulmonary vasculature in isolated rat lung. Exp Physiol (2008) 0.83
Integrins are involved in synaptogenesis, cell spreading, and adhesion in the postnatal brain. Brain Res Dev Brain Res (2003) 0.83
Imaging of lung function using synchrotron radiation computed tomography: what's new? Eur J Radiol (2008) 0.82