Published in Anesthesiology on June 01, 2016
Molecular Mechanisms of Anesthetic Neurotoxicity: A Review of the Current Literature. J Neurosurg Anesthesiol (2016) 0.79
Biomarkers, Genetics, and Epigenetic Studies to Explore the Neurocognitive Effects of Anesthesia in Children. J Neurosurg Anesthesiol (2016) 0.75
Caffeine combined with sedative/anesthetic drugs triggers widespread neuroapoptosis in a mouse model of prematurity. J Matern Fetal Neonatal Med (2016) 0.75
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods (2001) 414.27
Chromatin modifications and their function. Cell (2007) 55.98
Early exposure to anesthesia and learning disabilities in a population-based birth cohort. Anesthesiology (2009) 9.51
Sustained hippocampal chromatin regulation in a mouse model of depression and antidepressant action. Nat Neurosci (2006) 8.24
Early exposure to common anesthetic agents causes widespread neurodegeneration in the developing rat brain and persistent learning deficits. J Neurosci (2003) 7.42
Rubinstein-Taybi syndrome caused by mutations in the transcriptional co-activator CBP. Nature (1995) 7.11
Altered histone acetylation is associated with age-dependent memory impairment in mice. Science (2010) 6.38
Regulation of histone acetylation during memory formation in the hippocampus. J Biol Chem (2004) 5.99
CBP histone acetyltransferase activity is a critical component of memory consolidation. Neuron (2004) 5.40
Chromatin remodeling is a key mechanism underlying cocaine-induced plasticity in striatum. Neuron (2005) 5.09
Neurotrophins and neuronal plasticity. Science (1995) 4.53
Broad thumbs and toes and facial abnormalities. A possible mental retardation syndrome. Am J Dis Child (1963) 4.07
Epigenetic regulation of BDNF gene transcription in the consolidation of fear memory. J Neurosci (2008) 3.86
Transcriptional and epigenetic mechanisms of addiction. Nat Rev Neurosci (2011) 3.69
CREB required for the stability of new and reactivated fear memories. Nat Neurosci (2002) 3.28
Inhibition of p75 neurotrophin receptor attenuates isoflurane-mediated neuronal apoptosis in the neonatal central nervous system. Anesthesiology (2009) 3.26
BDNF: a key regulator for protein synthesis-dependent LTP and long-term memory? Neurobiol Learn Mem (2007) 2.96
Multiple roles of HDAC inhibition in neurodegenerative conditions. Trends Neurosci (2009) 2.95
Histone deacetylase inhibitors exhibit anti-inflammatory and neuroprotective effects in a rat permanent ischemic model of stroke: multiple mechanisms of action. J Pharmacol Exp Ther (2007) 2.90
Reversible inhibition of CREB/ATF transcription factors in region CA1 of the dorsal hippocampus disrupts hippocampus-dependent spatial memory. Neuron (2002) 2.87
Are anesthesia and surgery during infancy associated with altered academic performance during childhood? Anesthesiology (2012) 2.78
Anesthesia induces neuronal cell death in the developing rat brain via the intrinsic and extrinsic apoptotic pathways. Neuroscience (2005) 2.52
Comparative analysis of outcome measures used in examining neurodevelopmental effects of early childhood anesthesia exposure. Anesthesiology (2014) 2.50
Dexmedetomidine attenuates isoflurane-induced neurocognitive impairment in neonatal rats. Anesthesiology (2009) 2.24
Beyond transcription factors: the role of chromatin modifying enzymes in regulating transcription required for memory. Learn Mem (2008) 2.15
State-dependent Ras signaling and AMPA receptor trafficking. Genes Dev (2005) 1.86
A calcium microdomain near NMDA receptors: on switch for ERK-dependent synapse-to-nucleus communication. Nat Neurosci (2001) 1.81
Critical loss of CBP/p300 histone acetylase activity by caspase-6 during neurodegeneration. EMBO J (2003) 1.80
General anesthesia activates BDNF-dependent neuroapoptosis in the developing rat brain. Apoptosis (2006) 1.76
Hippocampal focal knockout of CBP affects specific histone modifications, long-term potentiation, and long-term memory. Neuropsychopharmacology (2011) 1.74
Altered histone acetylation at glutamate receptor 2 and brain-derived neurotrophic factor genes is an early event triggered by status epilepticus. J Neurosci (2002) 1.67
Developmental Stage-dependent persistent impact of propofol anesthesia on dendritic spines in the rat medial prefrontal cortex. Anesthesiology (2011) 1.55
Sodium butyrate ameliorates phenotypic expression in a transgenic mouse model of spinal and bulbar muscular atrophy. Hum Mol Genet (2004) 1.52
Melatonin reduces the severity of anesthesia-induced apoptotic neurodegeneration in the developing rat brain. Neurobiol Dis (2005) 1.52
Volatile anesthetics rapidly increase dendritic spine density in the rat medial prefrontal cortex during synaptogenesis. Anesthesiology (2010) 1.44
Role of neurotrophins in synapse development and plasticity. Rev Neurosci (1998) 1.43
Synaptic AMPA receptor exchange maintains bidirectional plasticity. Neuron (2006) 1.40
General anesthesia causes long-lasting disturbances in the ultrastructural properties of developing synapses in young rats. Neurotox Res (2009) 1.37
General Anesthesia Causes Long-term Impairment of Mitochondrial Morphogenesis and Synaptic Transmission in Developing Rat Brain. Anesthesiology (2011) 1.36
Is there a future for histone deacetylase inhibitors in the pharmacotherapy of psychiatric disorders? Mol Pharmacol (2009) 1.32
NKCC1-dependent GABAergic excitation drives synaptic network maturation during early hippocampal development. J Neurosci (2009) 1.26
The epigenetic effects of butyrate: potential therapeutic implications for clinical practice. Clin Epigenetics (2012) 1.26
The HOX homeodomain proteins block CBP histone acetyltransferase activity. Mol Cell Biol (2001) 1.24
The abolishment of anesthesia-induced cognitive impairment by timely protection of mitochondria in the developing rat brain: the importance of free oxygen radicals and mitochondrial integrity. Neurobiol Dis (2011) 1.22
Ablation of CBP in forebrain principal neurons causes modest memory and transcriptional defects and a dramatic reduction of histone acetylation but does not affect cell viability. J Neurosci (2011) 1.18
Changes in histone acetylation in the prefrontal cortex of ethanol-exposed adolescent rats are associated with ethanol-induced place conditioning. Neuropharmacology (2012) 1.16
Regulation of microglial inflammatory response by sodium butyrate and short-chain fatty acids. Br J Pharmacol (2004) 1.05
Making memories of stressful events: a journey along epigenetic, gene transcription, and signaling pathways. Front Psychiatry (2014) 1.01
Alcohol exposure decreases CREB binding protein expression and histone acetylation in the developing cerebellum. PLoS One (2011) 1.00
Expression levels influence ribosomal frameshifting at the tandem rare arginine codons AGG_AGG and AGA_AGA in Escherichia coli. J Bacteriol (2005) 1.00
Epigenetic modifications in the nervous system and their impact upon cognitive impairments. Neuropharmacology (2014) 0.95
Exposure to halothane and enflurane affects learning function of murine progeny. Anesth Analg (1981) 0.90
Is an epigenetic switch the key to persistent extinction? Neurobiol Learn Mem (2011) 0.89
Neonatal alcohol exposure and the hippocampus in developing male rats: effects on behaviorally induced CA1 c-Fos expression, CA1 pyramidal cell number, and contextual fear conditioning. Neuroscience (2012) 0.88
Histone deacetylases and mood disorders: epigenetic programming in gene-environment interactions. CNS Neurosci Ther (2010) 0.87
Sodium butyrate-induced histone acetylation strengthens the expression of cocaine-associated contextual memory. Neurobiol Learn Mem (2013) 0.87
Low concentrations of ketamine initiate dendritic atrophy of differentiated GABAergic neurons in culture. Toxicology (2007) 0.86
Pharmacological rescue of Ras signaling, GluA1-dependent synaptic plasticity, and learning deficits in a fragile X model. Genes Dev (2014) 0.86
Propofol induces MAPK/ERK cascade dependant expression of cFos and Egr-1 in rat hippocampal slices. BMC Res Notes (2010) 0.86
Phospho-acetylation of histone H3 in the amygdala after acute lithium chloride. Brain Res (2010) 0.85
Epigenetic regulations of immediate early genes expression involved in memory formation by the amyloid precursor protein of Alzheimer disease. PLoS One (2014) 0.84
Synaptogenesis regulates axotomy-induced activation of c-Jun-activator protein-1 transcription. J Neurosci (2006) 0.81
Npas4 expression in two experimental models of the barrel cortex plasticity. Neural Plast (2015) 0.79