Published in Beilstein J Org Chem on October 15, 2009
Continuous-flow catalytic asymmetric hydrogenations: Reaction optimization using FTIR inline analysis. Beilstein J Org Chem (2012) 0.98
Continuous-flow enantioselective α-aminoxylation of aldehydes catalyzed by a polystyrene-immobilized hydroxyproline. Beilstein J Org Chem (2011) 0.86
Continuous-flow hydration-condensation reaction: Synthesis of α,β-unsaturated ketones from alkynes and aldehydes by using a heterogeneous solid acid catalyst. Beilstein J Org Chem (2011) 0.82
Catalytic asymmetric organozinc additions to carbonyl compounds. Chem Rev (2001) 2.76
Greener approaches to organic synthesis using microreactor technology. Chem Rev (2007) 1.97
Selective hydrogenation of benzophenones to benzhydrols. Asymmetric synthesis of unsymmetrical diarylmethanols Org Lett (2000) 1.70
Combining enabling techniques in organic synthesis: continuous flow processes with heterogenized catalysts. Chemistry (2006) 1.49
A flow process for the multi-step synthesis of the alkaloid natural product oxomaritidine: a new paradigm for molecular assembly. Chem Commun (Camb) (2006) 1.35
Catalytic asymmetric approaches towards enantiomerically enriched diarylmethanols and diarylmethylamines. Chem Soc Rev (2006) 1.28
The use of a continuous flow-reactor employing a mixed hydrogen-liquid flow stream for the efficient reduction of imines to amines. Chem Commun (Camb) (2005) 1.27
Asymmetric reactions in continuous flow. Beilstein J Org Chem (2009) 1.23
Catalyzed Asymmetric Arylation Reactions. Angew Chem Int Ed Engl (2001) 1.13
A Superior, Readily Available Enantiopure Ligand for the Catalytic Enantioselective Addition of Diethylzinc to alpha-Substituted Aldehydes. J Org Chem (1998) 1.11
Catalyzed asymmetric aryl transfer reactions to aldehydes with boronic acids as aryl source. J Am Chem Soc (2002) 1.03
Asymmetric addition of alkylzinc reagents to cyclic alpha,beta-unsaturated ketones and a tandem enantioselective addition/diastereoselective epoxidation with dioxygen. J Am Chem Soc (2003) 1.02
The development and evaluation of a continuous flow process for the lipase-mediated oxidation of alkenes. Beilstein J Org Chem (2009) 1.02
Improving solid-supported catalyst productivity by using simplified packed-bed microreactors. Angew Chem Int Ed Engl (2007) 0.97
Polyionic polymers--heterogeneous media for metal nanoparticles as catalyst in Suzuki-Miyaura and Heck-Mizoroki reactions under flow conditions. Beilstein J Org Chem (2009) 0.97
From aryl bromides to enantioenriched benzylic alcohols in a single flask: Catalytic asymmetric arylation of aldehydes. Angew Chem Int Ed Engl (2006) 0.94
[3 + 2] Cycloaddition of acetylenes with azides to give 1,4-disubstituted 1,2,3-triazoles in a modular flow reactor. Org Biomol Chem (2007) 0.92
Controlling hazardous chemicals in microreactors: synthesis with iodine azide. Beilstein J Org Chem (2009) 0.92
practical implications of boron-to-zinc transmetalation for the catalytic asymmetric arylation of aldehydes. Angew Chem Int Ed Engl (2008) 0.88
Asymmetric, catalytic phenyl transfer to imines: highly enantioselective synthesis of diarylmethylamines. Angew Chem Int Ed Engl (2002) 0.88
The MPEG effect: improving asymmetric processes by simple additives. J Org Chem (2004) 0.87
Continuous flow based catch and release protocol for the synthesis of alpha-ketoesters. Beilstein J Org Chem (2009) 0.86
Enantioselective additions of diethylzinc and diphenylzinc to aldehydes using 2-dialkyl-aminomethyl-2'-hydroxy- 1,1'-binaphthyls. Org Lett (2002) 0.86
General method for the expedient synthesis of salt-free diorganozinc reagents using zinc methoxide. J Am Chem Soc (2008) 0.85
Michael reactions carried out using a bench-top flow system. Org Biomol Chem (2005) 0.84
From discovery to production: scale-out of continuous flow meso reactors. Beilstein J Org Chem (2009) 0.82
A biphasic oxidation of alcohols to aldehydes and ketones using a simplified packed-bed microreactor. Beilstein J Org Chem (2009) 0.82
5-(Pyrrolidin-2-yl)tetrazole-catalyzed aldol and mannich reactions: acceleration and lower catalyst loading in a continuous-flow reactor. Angew Chem Int Ed Engl (2009) 0.82
Synthesis of unsymmetrically substituted biaryls via sequential lithiation of dibromobiaryls using integrated microflow systems. Beilstein J Org Chem (2009) 0.81
Oxidative cyclization of alkenols with oxone using a miniflow reactor. Beilstein J Org Chem (2009) 0.78
2-Piperidino-1,1,2-triphenylethanol: a highly effective catalyst for the enantioselective arylation of aldehydes. J Org Chem (2004) 0.78
Organosilanols as catalysts in asymmetric aryl transfer reactions. Org Lett (2005) 0.78
Catalytic asymmetric aryl transfer reactions to aldehydes with Grignard reagents as the aryl source. Chemistry (2008) 0.77
Polystyrene-supported (R)-2-piperazino-1,1,2-triphenylethanol: a readily available supported ligand with unparalleled catalytic activity and enantioselectivity. J Org Chem (2005) 0.77
New silica-immobilized chiral amino alcohol for the enantioselective addition of diethylzinc to benzaldehyde. Org Lett (2003) 0.77
General approach to glycosidase inhibitors. Enantioselective synthesis of deoxymannojirimycin and swainsonine. J Org Chem (2005) 1.04
Mechanistic studies on the conversion of dicobalt octacarbonyl into colloidal cobalt nanoparticles. Langmuir (2006) 0.93
Toward an artificial aldolase. Org Lett (2007) 0.93
Suzuki cross-coupling on enantiomerically pure epoxides: efficient synthesis of diverse, modular amino alcohols from single enantiopure precursors. J Org Chem (2007) 0.92
A highly active catalyst for Huisgen 1,3-dipolar cycloadditions based on the tris(triazolyl)methanol-Cu(I) structure. Org Lett (2009) 0.91
A solid-supported organocatalyst for highly stereoselective, batch, and continuous-flow Mannich reactions. Chemistry (2009) 0.89
Intramolecular azide-alkyne cycloaddition for the fast assembly of structurally diverse, tricyclic 1,2,3-triazoles. Org Lett (2008) 0.89
Polystyrene-supported hydroxyproline: an insoluble, recyclable organocatalyst for the asymmetric aldol reaction in water. Org Lett (2006) 0.89
practical implications of boron-to-zinc transmetalation for the catalytic asymmetric arylation of aldehydes. Angew Chem Int Ed Engl (2008) 0.88
Asymmetric organocatalytic formal [2 + 2]-cycloadditions via bifunctional H-bond directing dienamine catalysis. J Am Chem Soc (2012) 0.87
Highly enantioselective alpha-aminoxylation of aldehydes and ketones with a polymer-supported organocatalyst. Org Lett (2007) 0.87
Catalytic enantioselective oxaziridination. J Am Chem Soc (2011) 0.87
Continuous-flow enantioselective α-aminoxylation of aldehydes catalyzed by a polystyrene-immobilized hydroxyproline. Beilstein J Org Chem (2011) 0.86
Two distinct conformations of GABA locked by embedding in the bicyclo[3.1.0]hexane core structure. ChemMedChem (2011) 0.86
Total synthesis and biological activity of 13,14-dehydro-12-oxo-phytodienoic acids (deoxy-J1-phytoprostanes). Chembiochem (2005) 0.86
New stereodivergent approach to 3-amino-2,3,6-trideoxysugars. Enantioselective synthesis of daunosamine, ristosamine, acosamine, and epi-daunosamine. Org Lett (2003) 0.84
Structural optimization of enantiopure 2-cyclialkylamino-2-aryl-1,1-diphenylethanols as catalytic ligands for enantioselective additions to aldehydes. J Org Chem (2008) 0.82
Organocatalytic activation of polycyclic aromatic compounds for asymmetric Diels-Alder reactions. Angew Chem Int Ed Engl (2012) 0.82
A click strategy for the immobilization of MacMillan organocatalysts onto polymers and magnetic nanoparticles. Org Lett (2012) 0.81
Metal-mediated cyclization of aryl and benzyl glycidyl ethers: a complete scenario. J Am Chem Soc (2008) 0.81
A multipurpose gold(I) precatalyst. Chem Commun (Camb) (2011) 0.81
Functionalized nanoparticles as catalysts for enantioselective processes. Org Biomol Chem (2009) 0.81
Dienamine-mediated inverse-electron-demand hetero-diels-alder reaction by using an enantioselective H-bond-directing strategy. Angew Chem Int Ed Engl (2012) 0.81
A solid-supported organocatalyst for continuous-flow enantioselective aldol reactions. ChemSusChem (2012) 0.80
Assessing the suitability of 1,2,3-triazole linkers for covalent immobilization of chiral ligands: application to enantioselective phenylation of aldehydes. J Org Chem (2007) 0.80
A polystyrene-supported 9-amino(9-deoxy)epi quinine derivative for continuous flow asymmetric Michael reactions. Org Biomol Chem (2015) 0.80
A computational study on the role of chiral N-oxides in enantioselective Pauson-Khand reactions. Chemistry (2011) 0.80
Highly enantioselective Michael additions in water catalyzed by a PS-supported pyrrolidine. Org Lett (2007) 0.79
Arene-metal π-complexation as a traceless reactivity enhancer for C-H arylation. J Am Chem Soc (2013) 0.79
Modular amino alcohol ligands containing bulky alkyl groups as chiral controllers for Et2Zn addition to aldehydes: illustration of a design principle. J Org Chem (2003) 0.78
Highly enantioselective dynamic kinetic resolution and desymmetrization processes by cyclocondensation of chiral aminoalcohols with racemic or prochiral delta-oxoacid derivatives. Chem Commun (Camb) (2005) 0.78
Michael reactions of titanium enolates of glycolic acid derivatives with the Weinreb and morpholine amides of acrylic acid. J Org Chem (2008) 0.78
2-Piperidino-1,1,2-triphenylethanol: a highly effective catalyst for the enantioselective arylation of aldehydes. J Org Chem (2004) 0.78
Enantioselective continuous-flow production of 3-indolylmethanamines mediated by an immobilized phosphoric acid catalyst. Chemistry (2014) 0.78
Paraldehyde as an acetaldehyde precursor in asymmetric Michael reactions promoted by site-isolated incompatible catalysts. Chemistry (2013) 0.78
Copper-free intramolecular alkyne-azide cycloadditions leading to seven-membered heterocycles. Org Lett (2011) 0.77
New silica-immobilized chiral amino alcohol for the enantioselective addition of diethylzinc to benzaldehyde. Org Lett (2003) 0.77
Highly enantioselective cross-aldol reactions of acetaldehyde mediated by a dual catalytic system operating under site isolation. Chemistry (2014) 0.77
Light-driven organocatalysis using inexpensive, nontoxic Bi2O3 as the photocatalyst. Angew Chem Int Ed Engl (2014) 0.77
Polystyrene-supported (R)-2-piperazino-1,1,2-triphenylethanol: a readily available supported ligand with unparalleled catalytic activity and enantioselectivity. J Org Chem (2005) 0.77
Structurally simple, modular amino alcohols for the recognition of carboxylic acids. Application to the development of a new chiral solvating agent. Org Lett (2005) 0.77
Air- and water-tolerant rare earth guanidinium BINOLate complexes as practical precatalysts in multifunctional asymmetric catalysis. J Am Chem Soc (2014) 0.77
PuPHOS: a synthetically useful chiral bidentate ligand for the intermolecular Pauson-Khand reaction. J Org Chem (2004) 0.77
Continuous flow, highly enantioselective Michael additions catalyzed by a PS-supported squaramide. Org Lett (2013) 0.77
Highly active organocatalysts for asymmetric anti-Mannich reactions. Chemistry (2011) 0.77
Enantiodivergent, catalytic asymmetric synthesis of gamma-amino vinyl sulfones. J Org Chem (2003) 0.77
Addition of diethylzinc to dicobalt hexacarbonyl complexes of alpha,beta-acetylenic aldehydes with virtually complete enantioselectivity. A formal synthesis of (+)-incrustoporin. Org Lett (2002) 0.76
Photoswitchable thioureas for the external manipulation of catalytic activity. Org Lett (2014) 0.76
Polystyrene-supported diarylprolinol ethers as highly efficient organocatalysts for Michael-type reactions. Chemistry (2011) 0.76
Mechanism of action of the cytotoxic macrolides amphidinolide X and J. Chembiochem (2011) 0.76
Phosphinite thioethers derived from chiral epoxides. Modular P,S-ligands for Pd-catalyzed asymmetric allylic substitutions. J Org Chem (2010) 0.75
Reaction of alkynes and azides: not triazoles through copper-acetylides but oxazoles through copper-nitrene intermediates. Chemistry (2014) 0.75
TEMPO-promoted Pauson-Khand reaction. Single-electron activation of cobalt-carbonyl bonds? Org Lett (2005) 0.75
Ring-closing metathesis of chiral allylamines. Enantioselective synthesis of (2S,3R,4S)-3,4-dihydroxyproline. J Org Chem (2002) 0.75
Deciphering the roles of multiple additives in organocatalyzed Michael additions. Chem Commun (Camb) (2016) 0.75
Boron trifluoride-induced, new stereospecific rearrangements of chiral epoxy ethers. Ready access to enantiopure 4-(diarylmethyl)-1,3-dioxolanes and 4,5-disubstituted tetrahydrobenzo[c]oxepin-4-ols. J Org Chem (2006) 0.75
Reversing the stereoselectivity of the intermolecular Pauson-Khand reaction: formation of endo-fused norbornadiene adducts. Org Lett (2002) 0.75
(S)-2-[(R)-fluoro(phenyl)methyl]oxirane: a general reagent for determining the ee of alpha-chiral amines. Org Lett (2005) 0.75
A theoretically-guided optimization of a new family of modular P,S-ligands for iridium-catalyzed hydrogenation of minimally functionalized olefins. Chemistry (2014) 0.75
Studies on the amination of aryl chlorides with a monoligated palladium catalyst: kinetic evidence for a cooperative mechanism. Chemistry (2012) 0.75
Catalytic Asymmetric [8+2] Annulation Reactions Promoted by a Recyclable Immobilized Isothiourea. Angew Chem Int Ed Engl (2017) 0.75
Ligand anatomy: probing remote substituent effects in asymmetric catalysis through NMR and kinetic analysis. Org Lett (2006) 0.75
TEMPO-mediated, room temperature synthesis of pure CoO nanoparticles. Chem Commun (Camb) (2006) 0.75
Synthesis of heavily substituted 1,2-amino alcohols in enantiomerically pure form. J Org Chem (2005) 0.75
Polystyrene-supported (2S)-(-)-3-exo-piperazinoisoborneol: an efficient catalyst for the batch and continuous flow production of enantiopure alcohols. Org Lett (2012) 0.75