David C Whitcomb

Author PubWeight™ 129.36‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Determinant-based classification of acute pancreatitis severity: an international multidisciplinary consultation. Ann Surg 2012 5.55
2 Comparison of BISAP, Ranson's, APACHE-II, and CTSI scores in predicting organ failure, complications, and mortality in acute pancreatitis. Am J Gastroenterol 2009 3.88
3 IAP Guidelines for the Surgical Management of Acute Pancreatitis. Pancreatology 2002 3.48
4 Clinical and genetic characteristics of hereditary pancreatitis in Europe. Clin Gastroenterol Hepatol 2004 2.82
5 Alcohol and smoking as risk factors in an epidemiology study of patients with chronic pancreatitis. Clin Gastroenterol Hepatol 2010 2.46
6 Blood urea nitrogen in the early assessment of acute pancreatitis: an international validation study. Arch Intern Med 2011 2.46
7 Alcohol consumption, cigarette smoking, and the risk of recurrent acute and chronic pancreatitis. Arch Intern Med 2009 2.23
8 Evaluation and management of autoimmune pancreatitis: experience at a large US center. Am J Gastroenterol 2009 2.04
9 Serum biomarker panels for the detection of pancreatic cancer. Clin Cancer Res 2011 1.98
10 The role of pancreatic cyst fluid molecular analysis in predicting cyst pathology. Clin Gastroenterol Hepatol 2005 1.78
11 Palladin mutation causes familial pancreatic cancer and suggests a new cancer mechanism. PLoS Med 2006 1.73
12 Comparison of existing clinical scoring systems to predict persistent organ failure in patients with acute pancreatitis. Gastroenterology 2012 1.71
13 Advances in counselling and surveillance of patients at risk for pancreatic cancer. Gut 2007 1.68
14 The role of alcohol and smoking in pancreatitis. Nat Rev Gastroenterol Hepatol 2010 1.67
15 Endoscopic therapy is effective for patients with chronic pancreatitis. Clin Gastroenterol Hepatol 2012 1.63
16 Feature Selection for Classification of SELDI-TOF-MS Proteomic Profiles. Appl Bioinformatics 2005 1.56
17 SPINK1/PSTI mutations are associated with tropical pancreatitis and type II diabetes mellitus in Bangladesh. Gastroenterology 2002 1.53
18 Inflammation and pancreatic cancer: an evidence-based review. Curr Opin Pharmacol 2009 1.46
19 Type of pain, pain-associated complications, quality of life, disability and resource utilisation in chronic pancreatitis: a prospective cohort study. Gut 2011 1.35
20 Pathways to injury in chronic pancreatitis: decoding the role of the high-risk SPINK1 N34S haplotype using meta-analysis. PLoS One 2008 1.32
21 Elevated serum creatinine as a marker of pancreatic necrosis in acute pancreatitis. Am J Gastroenterol 2009 1.30
22 Combined bicarbonate conductance-impairing variants in CFTR and SPINK1 variants are associated with chronic pancreatitis in patients without cystic fibrosis. Gastroenterology 2010 1.27
23 Obesity increases the severity of acute pancreatitis: performance of APACHE-O score and correlation with the inflammatory response. Pancreatology 2006 1.25
24 A new susceptibility locus for autosomal dominant pancreatic cancer maps to chromosome 4q32-34. Am J Hum Genet 2002 1.21
25 Revised Atlanta and determinant-based classification: application in a prospective cohort of acute pancreatitis patients. Am J Gastroenterol 2013 1.21
26 SPINK1 is a susceptibility gene for fibrocalculous pancreatic diabetes in subjects from the Indian subcontinent. Am J Hum Genet 2002 1.19
27 Role of BRCA1 and BRCA2 mutations in pancreatic cancer. Gut 2006 1.19
28 Smoking is underrecognized as a risk factor for chronic pancreatitis. Pancreatology 2011 1.19
29 Risk and markers of severe acute pancreatitis. Gastroenterol Clin North Am 2007 1.16
30 Hereditary pancreatitis: a model for inflammatory diseases of the pancreas. Best Pract Res Clin Gastroenterol 2002 1.16
31 Pancreatitis-diabetes-pancreatic cancer: summary of an NIDDK-NCI workshop. Pancreas 2013 1.15
32 Validation of reverse phase protein array for practical screening of potential biomarkers in serum and plasma: accurate detection of CA19-9 levels in pancreatic cancer. Proteomics 2008 1.15
33 Acute pancreatitis in children. Am J Gastroenterol 2002 1.13
34 Genetics of pancreatitis. Curr Opin Gastroenterol 2011 1.11
35 Chronic alcohol consumption accelerates fibrosis in response to cerulein-induced pancreatitis in rats. Am J Pathol 2005 1.10
36 Pancreatic response to endotoxin after chronic alcohol exposure: switch from apoptosis to necrosis? Am J Physiol Gastrointest Liver Physiol 2005 1.10
37 Diagnostic accuracy of interleukin-6 and interleukin-8 in predicting severe acute pancreatitis: a meta-analysis. Pancreatology 2010 1.09
38 Detection, evaluation and treatment of diabetes mellitus in chronic pancreatitis: recommendations from PancreasFest 2012. Pancreatology 2013 1.07
39 Physical and mental quality of life in chronic pancreatitis: a case-control study from the North American Pancreatitis Study 2 cohort. Pancreas 2013 1.06
40 Assessing the statistical significance of the achieved classification error of classifiers constructed using serum peptide profiles, and a prescription for random sampling repeated studies for massive high-throughput genomic and proteomic studies. Cancer Inform 2005 1.05
41 Serum immunoglobulin G fraction 4 levels in pancreatic cancer: elevations not associated with autoimmune pancreatitis. Arch Pathol Lab Med 2008 1.05
42 Association between calcium sensing receptor gene polymorphisms and chronic pancreatitis in a US population: role of serine protease inhibitor Kazal 1type and alcohol. World J Gastroenterol 2008 1.04
43 Limited contribution of the SPINK1 N34S mutation to the risk and severity of alcoholic chronic pancreatitis: a report from the United States. Dig Dis Sci 2003 1.03
44 Is the monocyte chemotactic protein-1 -2518 G allele a risk factor for severe acute pancreatitis? Clin Gastroenterol Hepatol 2005 1.01
45 Animal models in alcoholic pancreatitis--what can we learn? Pancreatology 2002 1.00
46 SPINK1 N34S is strongly associated with recurrent acute pancreatitis but is not a risk factor for the first or sentinel acute pancreatitis event. Am J Gastroenterol 2009 0.99
47 Sex differences in hepatic gene expression in a rat model of ethanol-induced liver injury. J Appl Physiol (1985) 2002 0.99
48 Whole exome sequencing identifies multiple, complex etiologies in an idiopathic hereditary pancreatitis kindred. JOP 2012 0.96
49 Pain in chronic pancreatitis and pancreatic cancer. Gastroenterol Clin North Am 2007 0.96
50 Does the pain-protective GTP cyclohydrolase haplotype significantly alter the pattern or severity of pain in humans with chronic pancreatitis? Mol Pain 2008 0.95
51 Molecular overlap of fly circadian rhythms and human pancreatic cancer. Cancer Lett 2006 0.95
52 Pooling-based genome-wide association study implicates gamma-glutamyltransferase 1 (GGT1) gene in pancreatic carcinogenesis. Pancreatology 2010 0.94
53 Analysis of tumor necrosis factor-alpha, transforming growth factor-beta 1, interleukin-10, and interferon-gamma polymorphisms in patients with alcoholic chronic pancreatitis. Alcohol 2004 0.94
54 Genetic issues in pediatric pancreatitis. Curr Gastroenterol Rep 2006 0.94
55 Alcohol and tobacco lower the age of presentation in sporadic pancreatic cancer in a dose-dependent manner: a multicenter study. Am J Gastroenterol 2012 0.93
56 The variable phenotype of the p.A16V mutation of cationic trypsinogen (PRSS1) in pancreatitis families. Gut 2009 0.92
57 Chronic alcohol consumption is a major risk factor for pancreatic necrosis in acute pancreatitis. Am J Gastroenterol 2006 0.92
58 PCCR: Pancreatic Cancer Collaborative Registry. Cancer Inform 2011 0.92
59 Current management and novel insights in acute pancreatitis. Expert Rev Gastroenterol Hepatol 2009 0.91
60 Inherited pancreatic cancer syndromes. Cancer J 2012 0.90
61 ABO blood group and chronic pancreatitis risk in the NAPS2 cohort. Pancreas 2011 0.90
62 Low serum adiponectin levels are associated with systemic organ failure in acute pancreatitis. Pancreas 2009 0.90
63 Inflammatory markers of disease severity in acute pancreatitis. Clin Lab Med 2005 0.89
64 Hereditary, familial, and idiopathic chronic pancreatitis are not associated with polymorphisms in the tumor necrosis factor alpha (TNF-alpha) promoter region or the TNF receptor 1 (TNFR1) gene. Genet Med 2003 0.89
65 Hereditary pancreatitis amlodipine trial: a pilot study of a calcium-channel blocker in hereditary pancreatitis. Pancreas 2007 0.88
66 Theories, mechanisms, and models of alcoholic chronic pancreatitis. Gastroenterol Clin North Am 2004 0.88
67 Genetics of pancreatitis: an update for clinicians and genetic counselors. Curr Gastroenterol Rep 2012 0.88
68 How to think about SPINK and pancreatitis. Am J Gastroenterol 2002 0.88
69 The functional angiotensin converting enzyme gene I/D polymorphism does not alter susceptibility to chronic pancreatitis. JOP 2004 0.87
70 Genetic predisposition to pancreatic cancer: a brief review. Am J Gastroenterol 2007 0.86
71 TNF-alpha gene (TNFA) variants increase risk for multi-organ dysfunction syndrome (MODS) in acute pancreatitis. Pancreatology 2012 0.85
72 Chronic alcohol-induced alterations in the pancreatic secretory control mechanisms. Dig Dis Sci 2004 0.85
73 The MCP-1 -2518 A/G polymorphism is not a susceptibility factor for chronic pancreatitis. Pancreatology 2006 0.84
74 Genetic analysis of the glutathione s-transferase genes MGST1, GSTM3, GSTT1, and GSTM1 in patients with hereditary pancreatitis. J Gastroenterol 2004 0.84
75 Toll-like receptor 4 polymorphisms in German and US patients are not associated with occurrence or severity of acute pancreatitis. Gut 2010 0.84
76 Genetic polymorphisms in alcoholic pancreatitis. Best Pract Res Clin Gastroenterol 2003 0.84
77 Keratin 8 mutations are not associated with familial, sporadic and alcoholic pancreatitis in a population from the United States. Pancreatology 2005 0.84
78 Genetics of acute and chronic pancreatitis. Curr Opin Gastroenterol 2013 0.83
79 Spectrum of use and effectiveness of endoscopic and surgical therapies for chronic pancreatitis in the United States. Pancreas 2014 0.83
80 Rapid evolution from the first episode of acute pancreatitis to chronic pancreatitis in human subjects. JOP 2007 0.82
81 Pancreatic cholesterol esterase, ES-10, and fatty acid ethyl ester synthase III gene expression are increased in the pancreas and liver but not in the brain or heart with long-term ethanol feeding in rats. Pancreas 2002 0.82
82 Functional polymorphisms of the GSTT-1 gene do not predict the severity of acute pancreatitis in the United States. Pancreatology 2007 0.81
83 Alcohol-associated pancreatitis. Gastroenterol Clin North Am 2007 0.81
84 Rapid adaptation of pancreatic exocrine function to short-term alcohol feeding in rats. Pancreatology 2005 0.81
85 Alcohol exacerbates LPS-induced fibrosis in subclinical acute pancreatitis. Am J Pathol 2013 0.80
86 Genetics and treatment options for recurrent acute and chronic pancreatitis. Curr Treat Options Gastroenterol 2014 0.80
87 Phenethyl isothiocyanate inhibits proliferation and induces apoptosis in pancreatic cancer cells in vitro and in a MIAPaca2 xenograft animal model. Nutr Cancer 2013 0.80
88 Serum proteomic patterns as a predictor of severity in acute pancreatitis. Pancreatology 2007 0.80
89 Predictors of severity and necrosis in acute pancreatitis. Gastroenterol Clin North Am 2004 0.80
90 Distribution of cholecystokinin-B receptor genotype between patients with pancreatic cancer and controls and its impact on survival. Pancreas 2015 0.80
91 Transforming growth factor-beta1, interleukin-10 and interferon-gamma cytokine polymorphisms in patients with hereditary, familial and sporadic chronic pancreatitis. Pancreatology 2004 0.80
92 Variation in the γ-glutamyltransferase 1 gene and risk of chronic pancreatitis. Pancreas 2013 0.79
93 Increased serum creatinine is associated with pancreatic necrosis in acute pancreatitis. Am J Gastroenterol 2010 0.79
94 Alcoholic pancreatitis. Gastroenterol Clin North Am 2004 0.79
95 The histopathology of PRSS1 hereditary pancreatitis. Am J Surg Pathol 2014 0.79
96 DNA mutational differences in cytological specimens from pancreatic cancer and cholangiocarcinoma. Pancreatology 2010 0.79
97 Low penetrance pancreatitis phenotype in a Venezuelan kindred with a PRSS1 R122H mutation. JOP 2013 0.79
98 Mucins in gastrointestinal cancers. Cancer Chemother Biol Response Modif 2003 0.78
99 Genetics of gastroesophageal reflux disease: a review. J Pediatr Gastroenterol Nutr 2002 0.78
100 Are genetic variants in the platelet-derived growth factor [beta] gene associated with chronic pancreatitis? Pancreas 2010 0.78
101 Diabetes mellitus in Tropical Chronic Pancreatitis Is Not Just a Secondary Type of Diabetes. Pancreatology 2004 0.78
102 Autosomal dominant infantile gastroesophageal reflux disease: exclusion of a 13q14 locus in five well characterized families. Am J Gastroenterol 2002 0.78
103 Genetics and pancreatic disease. Curr Opin Gastroenterol 2002 0.77
104 Genetic counseling for nonsyndromic pancreatitis. Gastroenterol Clin North Am 2007 0.77
105 Genetically defined models of chronic pancreatitis. Gastroenterology 2006 0.77
106 Angiotensin-converting enzyme gene DD genotype neither increases susceptibility to acute pancreatitis nor influences disease severity. HPB (Oxford) 2009 0.77
107 The premalignant lesions for pancreatic cancer; will Pan-IN's pan out? Gastroenterology 2002 0.77
108 Clinical Profile and Natural Course in a Large Cohort of Patients With Hypertriglyceridemia and Pancreatitis. J Clin Gastroenterol 2017 0.77
109 Clinical Profile, Etiology, and Treatment of Chronic Pancreatitis in North American Women: Analysis of a Large Multicenter Cohort. Pancreas 2016 0.77
110 Conservative treatment of chronic pancreatitis. Eur J Gastroenterol Hepatol 2002 0.76
111 Pancreatic Cancer Chemoprevention Translational Workshop: Meeting Report. Pancreas 2016 0.75
112 Patients With Sentinel Acute Pancreatitis of Alcoholic Etiology Are at Risk for Organ Failure and Pancreatic Necrosis: A Dual-Center Experience. Pancreas 2016 0.75
113 Increased Serum Insulin Exposure Does Not Affect Age or Stage of Pancreatic Adenocarcinoma Diagnosis in Patients With Diabetes Mellitus. Pancreas 2016 0.75
114 Isolated Peripancreatic Necrosis in Acute Pancreatitis Is Infrequent and Leads to Severe Clinical Course Only When Extensive: A Prospective Study From a US Tertiary Center. J Clin Gastroenterol 2016 0.75
115 Risk of New-Onset Diabetes Is Determined by Severity of Acute Pancreatitis. Pancreas 2016 0.75
116 Chronic Pancreatitis in the 21st Century - Research Challenges and Opportunities: Summary of a National Institute of Diabetes and Digestive and Kidney Diseases Workshop. Pancreas 2016 0.75
117 MUTYH exon 7 and 13 mutations associated with colorectal cancer (MAP syndrome) are not commonly associated with sporadic pancreatic cancer. Pancreatology 2010 0.75
118 The genetics of Shwachman-Diamond syndrome. Gastroenterology 2003 0.75
119 Increased expression of anion transporter SLC26A9 delays diabetes onset in cystic fibrosis. J Clin Invest 2019 0.75
120 The -251 A/T Polymorphism in the IL8 Promoter is a Risk Factor for Acute Pancreatitis. Pancreas 2017 0.75
121 Does anticipation exist in familial pancreatic cancer? Nat Clin Pract Gastroenterol Hepatol 2006 0.75
122 Minutes of the Business Meeting of the American Pancreatic Association Thursday, November 4, 2004. Pancreas 2005 0.75
123 Erratum: Admission Hematocrit and Rise in Blood Urea Nitrogen at 24 h Outperform other Laboratory Markers in Predicting Persistent Organ Failure and Pancreatic Necrosis in Acute Pancreatitis: A Post Hoc Analysis of Three Large Prospective Databases. Am J Gastroenterol 2016 0.75
124 Epidermal growth factor serum levels and the 61 G/A polymorphism in patients with acute pancreatitis. Dig Dis Sci 2010 0.75
125 Challenges of examining complex genetic disorders like GERD. J Pediatr Gastroenterol Nutr 2005 0.75
126 Acute pancreatitis in association with Campylobacter jejuni-associated diarrhea in a 15-year-old with CFTR mutations: is there a link? JOP 2006 0.75
127 The National Pancreas Foundation fellows symposium program 2006 to 2009. Pancreas 2010 0.75
128 The 5th International Symposium on Inherited Diseases of the Pancreas. Pancreatology 2006 0.75
129 APA Presidential Address: 2004. Pancreas 2005 0.75