PubRank

Hirotaka Osada

Author PubWeight™ 84.47‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Reduced expression of the let-7 microRNAs in human lung cancers in association with shortened postoperative survival. Cancer Res 2004 18.86
2 A polycistronic microRNA cluster, miR-17-92, is overexpressed in human lung cancers and enhances cell proliferation. Cancer Res 2005 10.46
3 Reduced expression of Dicer associated with poor prognosis in lung cancer patients. Cancer Sci 2005 4.55
4 Lineage-specific dependency of lung adenocarcinomas on the lung development regulator TTF-1. Cancer Res 2007 2.59
5 Expression profile-defined classification of lung adenocarcinoma shows close relationship with underlying major genetic changes and clinicopathologic behaviors. J Clin Oncol 2006 2.37
6 Epithelial to mesenchymal transition in an epidermal growth factor receptor-mutant lung cancer cell line with acquired resistance to erlotinib. J Thorac Oncol 2011 2.07
7 Reciprocal and complementary role of MET amplification and EGFR T790M mutation in acquired resistance to kinase inhibitors in lung cancer. Clin Cancer Res 2010 2.05
8 Prognostic model of pulmonary adenocarcinoma by expression profiling of eight genes as determined by quantitative real-time reverse transcriptase polymerase chain reaction. J Clin Oncol 2004 1.89
9 NKX2-1/TITF1/TTF-1-Induced ROR1 is required to sustain EGFR survival signaling in lung adenocarcinoma. Cancer Cell 2012 1.68
10 Conversion from the "oncogene addiction" to "drug addiction" by intensive inhibition of the EGFR and MET in lung cancer with activating EGFR mutation. Lung Cancer 2011 1.60
11 Variable DNA methylation patterns associated with progression of disease in hepatocellular carcinomas. Carcinogenesis 2008 1.57
12 Detailed characterization of a homozygously deleted region corresponding to a candidate tumor suppressor locus at 21q11-21 in human lung cancer. Genes Chromosomes Cancer 2008 1.41
13 Gene expression-based, individualized outcome prediction for surgically treated lung cancer patients. Oncogene 2004 1.41
14 Alterations of DNA methylation and histone modifications contribute to gene silencing in hepatocellular carcinomas. Hepatol Res 2007 1.40
15 LATS2 is a tumor suppressor gene of malignant mesothelioma. Cancer Res 2011 1.32
16 Aberrant hypermethylation of the CHFR prophase checkpoint gene in human lung cancers. Oncogene 2002 1.29
17 Interaction of GATA-3/T-bet transcription factors regulates expression of sialyl Lewis X homing receptors on Th1/Th2 lymphocytes. Proc Natl Acad Sci U S A 2006 1.26
18 CD74-NRG1 fusions in lung adenocarcinoma. Cancer Discov 2014 1.19
19 Significant up-regulation of a novel gene, CLCP1, in a highly metastatic lung cancer subline as well as in lung cancers in vivo. Oncogene 2002 1.19
20 Identification of decatenation G2 checkpoint impairment independently of DNA damage G2 checkpoint in human lung cancer cell lines. Cancer Res 2004 1.13
21 hDREF regulates cell proliferation and expression of ribosomal protein genes. Mol Cell Biol 2007 1.12
22 YAP1 is involved in mesothelioma development and negatively regulated by Merlin through phosphorylation. Carcinogenesis 2008 1.11
23 miR-375 is activated by ASH1 and inhibits YAP1 in a lineage-dependent manner in lung cancer. Cancer Res 2011 1.10
24 Combined inhibition of MET and EGFR suppresses proliferation of malignant mesothelioma cells. Carcinogenesis 2009 1.08
25 Integrated analysis of genetic and epigenetic alterations reveals CpG island methylator phenotype associated with distinct clinical characters of lung adenocarcinoma. Carcinogenesis 2012 1.07
26 Epigenetic profiles distinguish malignant pleural mesothelioma from lung adenocarcinoma. Cancer Res 2009 1.04
27 EGFR point mutation in non-small cell lung cancer is occasionally accompanied by a second mutation or amplification. Cancer Sci 2006 1.04
28 RhoB is frequently downregulated in non-small-cell lung cancer and resides in the 2p24 homozygous deletion region of a lung cancer cell line. Int J Cancer 2007 1.01
29 TGF-β synergizes with defects in the Hippo pathway to stimulate human malignant mesothelioma growth. J Exp Med 2012 1.01
30 Characteristic methylation profile in CpG island methylator phenotype-negative distal colorectal cancers. Int J Cancer 2010 0.99
31 Aberrant DNA methylation associated with aggressiveness of gastrointestinal stromal tumour. Gut 2011 0.98
32 Relationship of deregulated signaling converging onto mTOR with prognosis and classification of lung adenocarcinoma shown by two independent in silico analyses. Cancer Res 2009 0.94
33 Identification of frequent G(2) checkpoint impairment and a homozygous deletion of 14-3-3epsilon at 17p13.3 in small cell lung cancers. Cancer Res 2002 0.92
34 Activation of the PI3K-AKT pathway in human malignant mesothelioma cells. Mol Med Rep 2011 0.92
35 Novel NBS1 heterozygous germ line mutation causing MRE11-binding domain loss predisposes to common types of cancer. Cancer Res 2007 0.92
36 Contribution of microRNA-1275 to Claudin11 protein suppression via a polycomb-mediated silencing mechanism in human glioma stem-like cells. J Biol Chem 2012 0.91
37 The circadian clock gene BMAL1 is a novel therapeutic target for malignant pleural mesothelioma. Int J Cancer 2012 0.89
38 Detailed characterization of a homozygously deleted region corresponding to a candidate tumor suppressor locus at distal 17p13.3 in human lung cancer. Oncogene 2003 0.89
39 Regulation of DNA polymerase POLD4 influences genomic instability in lung cancer. Cancer Res 2010 0.88
40 Distinct profiles of epigenetic evolution between colorectal cancers with and without metastasis. Am J Pathol 2011 0.88
41 Decreased expression of 14-3-3sigma in neuroendocrine tumors is independent of origin and malignant potential. Oncogene 2002 0.86
42 mRNA expression of RRM1, ERCC1 and ERCC2 is not associated with chemosensitivity to cisplatin, carboplatin and gemcitabine in human lung cancer cell lines. Respirology 2008 0.84
43 Convergent signaling in the regulation of connective tissue growth factor in malignant mesothelioma: TGFβ signaling and defects in the Hippo signaling cascade. Cell Cycle 2012 0.84
44 Novel metastasis-related gene CIM functions in the regulation of multiple cellular stress-response pathways. Cancer Res 2010 0.79
45 Membranous expression of activated leukocyte cell adhesion molecule contributes to poor prognosis and malignant phenotypes of non-small-cell lung cancer. J Surg Res 2012 0.78
46 Activated leukocyte cell-adhesion molecule (ALCAM) promotes malignant phenotypes of malignant mesothelioma. J Thorac Oncol 2012 0.76
47 Relationship of mRNA expressions of RanBP2 and topoisomerase II isoforms to cytotoxicity of amrubicin in human lung cancer cell lines. Cancer Chemother Pharmacol 2009 0.75