Published in Epilepsia on August 01, 2010
Issues related to symptomatic and disease-modifying treatments affecting cognitive and neuropsychiatric comorbidities of epilepsy. Epilepsia (2013) 2.39
Ketogenic diets: new advances for metabolism-based therapies. Curr Opin Neurol (2012) 1.02
Finding a better drug for epilepsy: antiepileptogenesis targets. Epilepsia (2012) 0.99
The effects of the ketogenic diet on behavior and cognition. Epilepsy Res (2011) 0.96
The nervous system and metabolic dysregulation: emerging evidence converges on ketogenic diet therapy. Front Neurosci (2012) 0.92
A ketogenic diet reduces long-term potentiation in the dentate gyrus of freely behaving rats. J Neurophysiol (2011) 0.87
Purines and neuronal excitability: links to the ketogenic diet. Epilepsy Res (2011) 0.81
The collective therapeutic potential of cerebral ketone metabolism in traumatic brain injury. J Lipid Res (2014) 0.80
Effects of a ketogenic diet on hippocampal plasticity in freely moving juvenile rats. Physiol Rep (2015) 0.77
Hypothalamic hormones and metabolism. Epilepsy Res (2012) 0.75
Ketogenic diet: effects on expression of kindled seizures and behavior in adult rats. Epilepsia (1997) 2.65
Detrimental effects of the ketogenic diet on cognitive function in rats. Pediatr Res (2004) 2.60
Calorie restriction and ketogenic diet diminish neuronal excitability in rat dentate gyrus in vivo. Epilepsia (2003) 1.59
The ketogenic diet inhibits epileptogenesis in EL mice: a genetic model for idiopathic epilepsy. Epilepsia (2000) 1.25
Modafinil and memory: effects of modafinil on Morris water maze learning and Pavlovian fear conditioning. Behav Neurosci (2009) 1.21
Leptin contributes to slower weight gain in juvenile rodents on a ketogenic diet. Pediatr Res (2006) 1.18
Effects of ketogenic diet on development and behavior: preliminary report of a prospective study. Dev Med Child Neurol (2001) 1.11
Cognitive effects of ketogenic weight-reducing diets. Int J Obes Relat Metab Disord (1995) 0.96
Electrophysiological observations in hippocampal slices from rats treated with the ketogenic diet. Dev Neurosci (1999) 0.96
Nociception and locomotor activity are increased in ketogenic diet fed rats. Physiol Behav (2005) 0.92
Effect of the ketogenic diet on the activity level of Wistar rats. Pediatr Res (2004) 0.90
Clinical and biomarker changes in dominantly inherited Alzheimer's disease. N Engl J Med (2012) 14.14
Cerebrospinal fluid tau/beta-amyloid(42) ratio as a prediction of cognitive decline in nondemented older adults. Arch Neurol (2007) 10.75
Synaptic activity regulates interstitial fluid amyloid-beta levels in vivo. Neuron (2005) 7.53
Early exposure to common anesthetic agents causes widespread neurodegeneration in the developing rat brain and persistent learning deficits. J Neurosci (2003) 7.42
APOE predicts amyloid-beta but not tau Alzheimer pathology in cognitively normal aging. Ann Neurol (2010) 6.17
PGC-1alpha deficiency causes multi-system energy metabolic derangements: muscle dysfunction, abnormal weight control and hepatic steatosis. PLoS Biol (2005) 5.80
Neuropathology of nondemented aging: presumptive evidence for preclinical Alzheimer disease. Neurobiol Aging (2009) 4.36
Ghrelin controls hippocampal spine synapse density and memory performance. Nat Neurosci (2006) 4.25
Plasma multianalyte profiling in mild cognitive impairment and Alzheimer disease. Neurology (2012) 3.58
Long-term cognitive decline in older subjects was not attributable to noncardiac surgery or major illness. Anesthesiology (2009) 3.56
Preclinical Alzheimer's disease and its outcome: a longitudinal cohort study. Lancet Neurol (2013) 3.46
Anesthesia-induced developmental neuroapoptosis. Does it happen in humans? Anesthesiology (2004) 3.22
Sleep quality and preclinical Alzheimer disease. JAMA Neurol (2013) 3.11
Sex Is a major determinant of neuronal dysfunction in neurofibromatosis type 1. Ann Neurol (2014) 3.01
Measurements of age-related changes of physiological processes that predict lifespan of Caenorhabditis elegans. Proc Natl Acad Sci U S A (2004) 2.84
Predictors of preclinical Alzheimer disease and dementia: a clinicopathologic study. Arch Neurol (2005) 2.76
Total skeletal muscle PGC-1 deficiency uncouples mitochondrial derangements from fiber type determination and insulin sensitivity. Cell Metab (2010) 2.63
Alzheimer disease and cognitive reserve: variation of education effect with carbon 11-labeled Pittsburgh Compound B uptake. Arch Neurol (2008) 2.62
Domestic returns from investment in the control of tuberculosis in other countries. N Engl J Med (2005) 2.62
Autosomal-dominant Alzheimer's disease: a review and proposal for the prevention of Alzheimer's disease. Alzheimers Res Ther (2011) 2.51
Validity and reliability of the AD8 informant interview in dementia. Neurology (2006) 2.42
Incidence, seasonality and mortality associated with influenza pneumonia in Thailand: 2005-2008. PLoS One (2009) 2.38
Longitudinal driving performance in early-stage dementia of the Alzheimer type. J Am Geriatr Soc (2003) 2.37
Acquired deficit of forebrain glucocorticoid receptor produces depression-like changes in adrenal axis regulation and behavior. Proc Natl Acad Sci U S A (2004) 2.11
Education and Alzheimer disease without dementia: support for the cognitive reserve hypothesis. Neurology (2007) 2.06
Plasma cortisol and progression of dementia in subjects with Alzheimer-type dementia. Am J Psychiatry (2006) 2.05
Brain fatty acid synthase activates PPARalpha to maintain energy homeostasis. J Clin Invest (2007) 2.03
SARS in healthcare facilities, Toronto and Taiwan. Emerg Infect Dis (2004) 1.95
Obesity and hypertriglyceridemia produce cognitive impairment. Endocrinology (2008) 1.94
Ataxia and paroxysmal dyskinesia in mice lacking axonally transported FGF14. Neuron (2002) 1.91
Developing an international network for Alzheimer research: The Dominantly Inherited Alzheimer Network. Clin Investig (Lond) (2012) 1.90
Treatment with an amyloid-beta antibody ameliorates plaque load, learning deficits, and hippocampal long-term potentiation in a mouse model of Alzheimer's disease. J Neurosci (2005) 1.90
Drug-induced apoptotic neurodegeneration in the developing brain. Brain Pathol (2002) 1.85
Cerebrospinal fluid sulfatide is decreased in subjects with incipient dementia. Ann Neurol (2003) 1.78
Multiplexed immunoassay panel identifies novel CSF biomarkers for Alzheimer's disease diagnosis and prognosis. PLoS One (2011) 1.74
Sirt1 extends life span and delays aging in mice through the regulation of Nk2 homeobox 1 in the DMH and LH. Cell Metab (2013) 1.74
Impaired glial glutamate transport in a mouse tuberous sclerosis epilepsy model. Ann Neurol (2003) 1.72
Genetic and pharmacological factors that influence reproductive aging in nematodes. PLoS Genet (2006) 1.70
Cerebrospinal fluid biomarkers and rate of cognitive decline in very mild dementia of the Alzheimer type. Arch Neurol (2009) 1.68
Do pediatric drugs cause developing neurons to commit suicide? Trends Pharmacol Sci (2004) 1.67
Quality of malnutrition assessment surveys conducted during famine in Ethiopia. JAMA (2004) 1.64
Cerebrospinal fluid Aβ42, phosphorylated Tau181, and resting-state functional connectivity. JAMA Neurol (2013) 1.60
YKL-40: a novel prognostic fluid biomarker for preclinical Alzheimer's disease. Biol Psychiatry (2010) 1.59
Regional variability of imaging biomarkers in autosomal dominant Alzheimer's disease. Proc Natl Acad Sci U S A (2013) 1.58
Circadian clock proteins regulate neuronal redox homeostasis and neurodegeneration. J Clin Invest (2013) 1.57
Survival and mortality differences between dementia with Lewy bodies vs Alzheimer disease. Neurology (2006) 1.57
Forebrain glucocorticoid receptors modulate anxiety-associated locomotor activation and adrenal responsiveness. J Neurosci (2006) 1.56
Disrupted membrane homeostasis and accumulation of ubiquitinated proteins in a mouse model of infantile neuroaxonal dystrophy caused by PLA2G6 mutations. Am J Pathol (2008) 1.54
SIRT1 promotes the central adaptive response to diet restriction through activation of the dorsomedial and lateral nuclei of the hypothalamus. J Neurosci (2010) 1.51
Visinin-like protein-1: diagnostic and prognostic biomarker in Alzheimer disease. Ann Neurol (2011) 1.51
Comparison of analytical platforms for cerebrospinal fluid measures of β-amyloid 1-42, total tau, and p-tau181 for identifying Alzheimer disease amyloid plaque pathology. Arch Neurol (2011) 1.50
Longitudinal change in CSF biomarkers in autosomal-dominant Alzheimer's disease. Sci Transl Med (2014) 1.45
FGF14 regulates the intrinsic excitability of cerebellar Purkinje neurons. Neurobiol Dis (2008) 1.43
White matter lesions are prevalent but differentially related with cognition in aging and early Alzheimer disease. Arch Neurol (2005) 1.43
Central amygdala glucocorticoid receptor action promotes fear-associated CRH activation and conditioning. Proc Natl Acad Sci U S A (2008) 1.41
Amyloid-beta plaque growth in cognitively normal adults: longitudinal [11C]Pittsburgh compound B data. Ann Neurol (2011) 1.40
Abnormal glutamate homeostasis and impaired synaptic plasticity and learning in a mouse model of tuberous sclerosis complex. Neurobiol Dis (2007) 1.37
Increased soluble amyloid-beta peptide and memory deficits in amyloid model mice overexpressing the low-density lipoprotein receptor-related protein. Proc Natl Acad Sci U S A (2004) 1.36
Impaired spatial learning and defective theta burst induced LTP in mice lacking fibroblast growth factor 14. Neurobiol Dis (2007) 1.34
Neuropathologic criteria for diagnosing Alzheimer disease in persons with pure dementia of Alzheimer type. J Neuropathol Exp Neurol (2004) 1.33
Reaction to a dementia diagnosis in individuals with Alzheimer's disease and mild cognitive impairment. J Am Geriatr Soc (2008) 1.31
Antisense reduction of tau in adult mice protects against seizures. J Neurosci (2013) 1.29
Cerebellar synaptic defects and abnormal motor behavior in mice lacking alpha- and beta-dystrobrevin. J Neurosci (2006) 1.28
Low doses of memantine disrupt memory in adult rats. J Neurosci (2006) 1.27
Repetitive hypoglycemia in young rats impairs hippocampal long-term potentiation. Pediatr Res (2003) 1.24
Leptin inhibits 4-aminopyridine- and pentylenetetrazole-induced seizures and AMPAR-mediated synaptic transmission in rodents. J Clin Invest (2008) 1.23
Development of sensory, motor and behavioral deficits in the murine model of Sanfilippo syndrome type B. PLoS One (2007) 1.23
Gender differences in free radical homeostasis during aging: shorter-lived female C57BL6 mice have increased oxidative stress. Aging Cell (2006) 1.22
Ketogenic diet reduces hypoglycemia-induced neuronal death in young rats. Neurosci Lett (2005) 1.21
A carboxyfullerene SOD mimetic improves cognition and extends the lifespan of mice. Neurobiol Aging (2006) 1.19
Reduced striatal dopamine underlies the attention system dysfunction in neurofibromatosis-1 mutant mice. Hum Mol Genet (2010) 1.18
Leptin contributes to slower weight gain in juvenile rodents on a ketogenic diet. Pediatr Res (2006) 1.18
Therapeutic efficacy of bone marrow transplant, intracranial AAV-mediated gene therapy, or both in the mouse model of MPS IIIB. Mol Ther (2010) 1.16
Impaired default network functional connectivity in autosomal dominant Alzheimer disease. Neurology (2013) 1.16
Recurrent moderate hypoglycemia ameliorates brain damage and cognitive dysfunction induced by severe hypoglycemia. Diabetes (2010) 1.15
The ketogenic diet inhibits the mammalian target of rapamycin (mTOR) pathway. Epilepsia (2011) 1.14
Multiple episodes of mild traumatic brain injury result in impaired cognitive performance in mice. Acad Emerg Med (2004) 1.14
Cerebellar pathology and motor deficits in the palmitoyl protein thioesterase 1-deficient mouse. Exp Neurol (2009) 1.13
Bone marrow transplantation augments the effect of brain- and spinal cord-directed adeno-associated virus 2/5 gene therapy by altering inflammation in the murine model of globoid-cell leukodystrophy. J Neurosci (2011) 1.12
The enigma of fetal alcohol neurotoxicity. Ann Med (2002) 1.08
Characterizing learning deficits and hippocampal neuron loss following transient global cerebral ischemia in rats. Brain Res (2005) 1.08
The disruption of Celf6, a gene identified by translational profiling of serotonergic neurons, results in autism-related behaviors. J Neurosci (2013) 1.05
A physiological role for amyloid-beta protein:enhancement of learning and memory. J Alzheimers Dis (2010) 1.04
In vivo imaging of dendritic spines during electrographic seizures. Ann Neurol (2005) 1.02
Commentary on "a roadmap for the prevention of dementia II: Leon Thal Symposium 2008." Prevention trials in persons at risk for dominantly inherited Alzheimer's disease: opportunities and challenges. Alzheimers Dement (2009) 1.02
Evaluating acceptability and completeness of overseas immunization records of internationally adopted children. Pediatrics (2002) 1.00
Loss of RBPj in postnatal excitatory neurons does not cause neurodegeneration or memory impairments in aged mice. PLoS One (2012) 0.98
Dopamine deficiency underlies learning deficits in neurofibromatosis-1 mice. Ann Neurol (2012) 0.97
Interaction of neuritic plaques and education predicts dementia. Alzheimer Dis Assoc Disord (2008) 0.97
Alzheimer disease family history impacts resting state functional connectivity. Ann Neurol (2012) 0.97
Exact confidence interval estimation for the difference in diagnostic accuracy with three ordinal diagnostic groups. J Stat Plan Inference (2010) 0.96
Long-term memory deficits in Pavlovian fear conditioning in Ca2+/calmodulin kinase kinase alpha-deficient mice. Mol Cell Biol (2006) 0.96
An animal model of generalized nonconvulsive status epilepticus: immediate characteristics and long-term effects. Exp Neurol (2003) 0.95