Erik I Christensen

Author PubWeight™ 50.12‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Cubilin is essential for albumin reabsorption in the renal proximal tubule. J Am Soc Nephrol 2010 2.42
2 Generation of urinary albumin fragments does not require proximal tubular uptake. J Am Soc Nephrol 2012 2.19
3 Increased lysosomal proteolysis counteracts protein accumulation in the proximal tubule during focal segmental glomerulosclerosis. Kidney Int 2013 2.12
4 The functional cobalamin (vitamin B12)-intrinsic factor receptor is a novel complex of cubilin and amnionless. Blood 2003 1.91
5 Aquaporin-1 is not expressed in descending thin limbs of short-loop nephrons. J Am Soc Nephrol 2007 1.66
6 Urinary protein excretion pattern and renal expression of megalin and cubilin in nephropathic cystinosis. Am J Kidney Dis 2008 1.50
7 Statin-sensitive endocytosis of albumin by glomerular podocytes. Am J Physiol Renal Physiol 2006 1.27
8 Arginase 1 is expressed in myelocytes/metamyelocytes and localized in gelatinase granules of human neutrophils. Blood 2007 1.26
9 Amnionless function is required for cubilin brush-border expression and intrinsic factor-cobalamin (vitamin B12) absorption in vivo. Blood 2005 1.25
10 Endocytosis provides a major alternative pathway for lysosomal biogenesis in kidney proximal tubular cells. Proc Natl Acad Sci U S A 2007 1.21
11 Megalin and cubilin are endocytic receptors involved in renal clearance of hemoglobin. J Am Soc Nephrol 2002 1.21
12 ZONAB promotes proliferation and represses differentiation of proximal tubule epithelial cells. J Am Soc Nephrol 2010 1.20
13 Three-dimensional reconstruction of the mouse nephron. J Am Soc Nephrol 2005 1.17
14 Neutrophil elastase depends on serglycin proteoglycan for localization in granules. Blood 2007 1.16
15 Receptor-mediated endocytosis of α-galactosidase A in human podocytes in Fabry disease. PLoS One 2011 1.15
16 Transforming growth factor-beta1 reduces megalin- and cubilin-mediated endocytosis of albumin in proximal-tubule-derived opossum kidney cells. J Physiol 2003 1.13
17 A patient with cubilin deficiency. N Engl J Med 2011 1.10
18 Megalin and cubilin--the story of two multipurpose receptors unfolds. Nephrol Dial Transplant 2002 1.09
19 Mouse model of proximal tubule endocytic dysfunction. Nephrol Dial Transplant 2011 1.05
20 Plasma protein haptoglobin modulates renal iron loading. Am J Pathol 2005 1.04
21 Digital three-dimensional reconstruction and ultrastructure of the mouse proximal tubule. J Am Soc Nephrol 2003 0.99
22 Renal tubular reabsorption of folate mediated by folate binding protein 1. J Am Soc Nephrol 2005 0.96
23 Divalent metal transporter 1 in the kidney proximal tubule is expressed in late endosomes/lysosomal membranes: implications for renal handling of protein-metal complexes. Am J Physiol Renal Physiol 2006 0.94
24 Renal proximal tubular dysfunction is a major determinant of urinary connective tissue growth factor excretion. Am J Physiol Renal Physiol 2010 0.90
25 Megalin is essential for renal proximal tubule reabsorption and accumulation of transcobalamin-B(12). Am J Physiol Renal Physiol 2002 0.89
26 In vivo confocal laser scanning microscopy and micropuncture in intact rat. Nephron Exp Nephrol 2005 0.88
27 Megalin binds and mediates cellular internalization of folate binding protein. FEBS J 2005 0.87
28 Mannose 6-phosphate receptor and sortilin mediated endocytosis of α-galactosidase A in kidney endothelial cells. PLoS One 2012 0.86
29 Spatial organization of the vascular bundle and the interbundle region: three-dimensional reconstruction at the inner stripe of the outer medulla in the mouse kidney. Am J Physiol Renal Physiol 2013 0.86
30 EUNEFRON, the European Network for the Study of Orphan Nephropathies. Nephrol Dial Transplant 2009 0.86
31 Renal phenotypic investigations of megalin-deficient patients: novel insights into tubular proteinuria and albumin filtration. Nephrol Dial Transplant 2012 0.85
32 The effect of progressive glomerular disease on megalin-mediated endocytosis in the kidney. Nephrol Dial Transplant 2010 0.85
33 NHE3 serves as a molecular tool for cAMP-mediated regulation of receptor-mediated endocytosis. Am J Physiol Renal Physiol 2002 0.84
34 Renal uptake of 99mTc-dimercaptosuccinic acid is dependent on normal proximal tubule receptor-mediated endocytosis. J Nucl Med 2012 0.84
35 Long-term enzyme replacement therapy is associated with reduced proteinuria and preserved proximal tubular function in women with Fabry disease. Nephrol Dial Transplant 2013 0.84
36 Renal uptake of myoglobin is mediated by the endocytic receptors megalin and cubilin. Am J Physiol Renal Physiol 2003 0.83
37 Impaired PTH-induced endocytotic down-regulation of the renal type IIa Na+/Pi-cotransporter in RAP-deficient mice with reduced megalin expression. Pflugers Arch 2003 0.81
38 The soluble intracellular domain of megalin does not affect renal proximal tubular function in vivo. Kidney Int 2010 0.81
39 SorLA controls neurotrophic activity by sorting of GDNF and its receptors GFRα1 and RET. Cell Rep 2013 0.81
40 Direct physical contact between intercalated cells in the distal convoluted tubule and the afferent arteriole in mouse kidneys. PLoS One 2013 0.81
41 Haploinsufficiency of the ammonia transporter Rhcg predisposes to chronic acidosis: Rhcg is critical for apical and basolateral ammonia transport in the mouse collecting duct. J Biol Chem 2012 0.81
42 Megalin-deficiency causes high myopia, retinal pigment epithelium-macromelanosomes and abnormal development of the ciliary body in mice. Cell Tissue Res 2014 0.80
43 Cellular and intracellular distribution of recombinant activated factor VII in the rat liver. Thromb Haemost 2010 0.78
44 Biodistribution and PET imaging of a novel [68Ga]-anti-CD163-antibody conjugate in rats with collagen-induced arthritis and in controls. Mol Imaging Biol 2015 0.78
45 The unsialylated subpopulation of recombinant activated factor VII binds to the asialo-glycoprotein receptor (ASGPR) on primary rat hepatocytes. Thromb Haemost 2010 0.77
46 Renal uptake of the antiapoptotic protein survivin is mediated by megalin at the apical membrane of the proximal tubule. Am J Physiol Renal Physiol 2013 0.77
47 Untargeted Metabolomics Analysis of ABCC6-Deficient Mice Discloses an Altered Metabolic Liver Profile. J Proteome Res 2016 0.77
48 In-depth phenotyping of a Donnai-Barrow patient helps clarify proximal tubule dysfunction. Pediatr Nephrol 2015 0.76
49 Diagnostic dilemma: a young woman with Fabry disease symptoms, no family history, and a "sequencing cryptic" α-galactosidase a large deletion. Mol Genet Metab 2011 0.76
50 The authors reply. Kidney Int 2013 0.75