Published in Blood on February 01, 2007
Heparan sulfate proteoglycans. Cold Spring Harb Perspect Biol (2011) 2.96
Neutrophil elastase, proteinase 3, and cathepsin G as therapeutic targets in human diseases. Pharmacol Rev (2010) 1.97
Mast cell-derived particles deliver peripheral signals to remote lymph nodes. J Exp Med (2009) 1.42
Neutrophil serine proteases fine-tune the inflammatory response. Int J Biochem Cell Biol (2007) 1.12
Breast cancer cell uptake of the inflammatory mediator neutrophil elastase triggers an anticancer adaptive immune response. Cancer Res (2012) 1.12
Heparan sulfate proteoglycans: a GAGgle of skeletal-hematopoietic regulators. Dev Dyn (2008) 1.10
Serglycin is a major proteoglycan in polarized human endothelial cells and is implicated in the secretion of the chemokine GROalpha/CXCL1. J Biol Chem (2010) 0.96
Granule protein processing and regulated secretion in neutrophils. Front Immunol (2014) 0.95
Serglycin proteoglycan deletion induces defects in platelet aggregation and thrombus formation in mice. Blood (2007) 0.93
Gene expression profiling in dermatitis herpetiformis skin lesions. Clin Dev Immunol (2012) 0.90
Serglycin: at the crossroad of inflammation and malignancy. Front Oncol (2014) 0.87
A role for serglycin proteoglycan in mast cell apoptosis induced by a secretory granule-mediated pathway. J Biol Chem (2010) 0.86
Canine uterine bacterial infection induces upregulation of proteolysis-related genes and downregulation of homeobox and zinc finger factors. PLoS One (2009) 0.86
Comparative glycomics of leukocyte glycosaminoglycans. FEBS J (2013) 0.85
Serglycin in human cancers. Chin J Cancer (2011) 0.85
Serglycin-independent release of active mast cell proteases in response to Toxoplasma gondii infection. J Biol Chem (2010) 0.84
Thrombospondin-1 restrains neutrophil granule serine protease function and regulates the innate immune response during Klebsiella pneumoniae infection. Mucosal Immunol (2014) 0.83
SerpinB1 is critical for neutrophil survival through cell-autonomous inhibition of cathepsin G. Blood (2013) 0.82
Serglycin proteoglycan promotes apoptotic versus necrotic cell death in mast cells. J Biol Chem (2012) 0.82
The effect of acute and long-term physical activity on extracellular matrix and serglycin in human skeletal muscle. Physiol Rep (2015) 0.82
Heparan Sulfate Modulates Neutrophil and Endothelial Function in Antibacterial Innate Immunity. Infect Immun (2015) 0.80
Loss of Serglycin Promotes Primary Tumor Growth and Vessel Functionality in the RIP1-Tag2 Mouse Model for Spontaneous Insulinoma Formation. PLoS One (2015) 0.79
Processing of Neutrophil α-Defensins Does Not Rely on Serine Proteases In Vivo. PLoS One (2015) 0.77
Mechanism of heparin acceleration of tissue inhibitor of metalloproteases-1 (TIMP-1) degradation by the human neutrophil elastase. PLoS One (2011) 0.77
Age-Appropriate Functions and Dysfunctions of the Neonatal Neutrophil. Front Pediatr (2017) 0.76
Proteoglycans in Normal and Healing Skin. Adv Wound Care (New Rochelle) (2015) 0.76
Targeting Serglycin Prevents Metastasis in Murine Mammary Carcinoma. PLoS One (2016) 0.76
Serglycin proteoglycans limit enteropathy in Trichinella spiralis-infected mice. BMC Immunol (2016) 0.75
S-maltoheptaose targets syndecan-bound effectors to reduce smoking-related neutrophilic inflammation. Sci Rep (2015) 0.75
Mast Cells Produce a Unique Chondroitin Sulfate Epitope. J Histochem Cytochem (2015) 0.75
Expression and Localization of Cathepsins B, D, and G in Two Cancer Stem Cell Subpopulations in Moderately Differentiated Oral Tongue Squamous Cell Carcinoma. Front Med (Lausanne) (2017) 0.75
Paucimannose-Rich N-glycosylation of Spatiotemporally Regulated Human Neutrophil Elastase Modulates Its Immune Functions. Mol Cell Proteomics (2017) 0.75
The neutrophil lipocalin NGAL is a bacteriostatic agent that interferes with siderophore-mediated iron acquisition. Mol Cell (2002) 6.81
Human cathelicidin antimicrobial peptide (CAMP) gene is a direct target of the vitamin D receptor and is strongly up-regulated in myeloid cells by 1,25-dihydroxyvitamin D3. FASEB J (2005) 4.36
Urinary neutrophil gelatinase-associated lipocalin and acute kidney injury after cardiac surgery. Am J Kidney Dis (2008) 3.95
Neutrophil granules and secretory vesicles in inflammation. Microbes Infect (2003) 3.56
Structure and biogenesis of the capsular F1 antigen from Yersinia pestis: preserved folding energy drives fiber formation. Cell (2003) 3.15
Liver is the major source of elevated serum lipocalin-2 levels after bacterial infection or partial hepatectomy: a critical role for IL-6/STAT3. Hepatology (2015) 3.10
Phenotypic and functional plasticity of cells of innate immunity: macrophages, mast cells and neutrophils. Nat Immunol (2011) 2.92
Mast cells can enhance resistance to snake and honeybee venoms. Science (2006) 2.72
The cathelicidin anti-microbial peptide LL-37 is involved in re-epithelialization of human skin wounds and is lacking in chronic ulcer epithelium. J Invest Dermatol (2003) 2.50
Vitamin d-directed rheostatic regulation of monocyte antibacterial responses. J Immunol (2009) 2.45
Cubilin is essential for albumin reabsorption in the renal proximal tubule. J Am Soc Nephrol (2010) 2.42
Low plasma level of cathelicidin antimicrobial peptide (hCAP18) predicts increased infectious disease mortality in patients undergoing hemodialysis. Clin Infect Dis (2009) 2.34
Phosphorylation of Bax Ser184 by Akt regulates its activity and apoptosis in neutrophils. J Biol Chem (2004) 2.30
KRAB zinc finger proteins: an analysis of the molecular mechanisms governing their increase in numbers and complexity during evolution. Mol Biol Evol (2002) 2.27
Neutrophil gelatinase-associated lipocalin is up-regulated in human epithelial cells by IL-1 beta, but not by TNF-alpha. J Immunol (2003) 2.25
Plectasin is a peptide antibiotic with therapeutic potential from a saprophytic fungus. Nature (2005) 2.23
Generation of urinary albumin fragments does not require proximal tubular uptake. J Am Soc Nephrol (2012) 2.19
The antimicrobial peptide LL-37 activates innate immunity at the airway epithelial surface by transactivation of the epidermal growth factor receptor. J Immunol (2003) 2.15
Increased lysosomal proteolysis counteracts protein accumulation in the proximal tubule during focal segmental glomerulosclerosis. Kidney Int (2013) 2.12
The endocytic receptor megalin binds the iron transporting neutrophil-gelatinase-associated lipocalin with high affinity and mediates its cellular uptake. FEBS Lett (2005) 1.96
The 5'-AMP-activated protein kinase gamma3 isoform has a key role in carbohydrate and lipid metabolism in glycolytic skeletal muscle. J Biol Chem (2004) 1.94
The functional cobalamin (vitamin B12)-intrinsic factor receptor is a novel complex of cubilin and amnionless. Blood (2003) 1.91
Receptor binding studies disclose a novel class of high-affinity inhibitors of the Escherichia coli FimH adhesin. Mol Microbiol (2005) 1.90
Wound healing and expression of antimicrobial peptides/polypeptides in human keratinocytes, a consequence of common growth factors. J Immunol (2003) 1.88
IL-1beta-specific up-regulation of neutrophil gelatinase-associated lipocalin is controlled by IkappaB-zeta. J Immunol (2006) 1.87
The transcriptional program of terminal granulocytic differentiation. Blood (2004) 1.80
Targeted disruption of a murine glucuronyl C5-epimerase gene results in heparan sulfate lacking L-iduronic acid and in neonatal lethality. J Biol Chem (2003) 1.70
A key role for mast cell chymase in the activation of pro-matrix metalloprotease-9 and pro-matrix metalloprotease-2. J Biol Chem (2004) 1.70
Mast cell proteases. Adv Immunol (2007) 1.70
Self-assembly of spider silk proteins is controlled by a pH-sensitive relay. Nature (2010) 1.68
Groups IV, V, and X phospholipases A2s in human neutrophils: role in eicosanoid production and gram-negative bacterial phospholipid hydrolysis. J Biol Chem (2001) 1.67
Rab27b regulates number and secretion of platelet dense granules. Proc Natl Acad Sci U S A (2007) 1.66
Aquaporin-1 is not expressed in descending thin limbs of short-loop nephrons. J Am Soc Nephrol (2007) 1.66
Neutrophil gelatinase-associated lipocalin (NGAL) an early-screening biomarker for ovarian cancer: NGAL is associated with epidermal growth factor-induced epithelio-mesenchymal transition. Int J Cancer (2007) 1.63
Candida albicans escapes from mouse neutrophils. J Leukoc Biol (2013) 1.56
Urinary protein excretion pattern and renal expression of megalin and cubilin in nephropathic cystinosis. Am J Kidney Dis (2008) 1.50
Critical role of mast cell chymase in mouse abdominal aortic aneurysm formation. Circulation (2009) 1.43
Processing of seminal plasma hCAP-18 to ALL-38 by gastricsin: a novel mechanism of generating antimicrobial peptides in vagina. J Biol Chem (2003) 1.38
Antimicrobial protein hCAP18/LL-37 is highly expressed in breast cancer and is a putative growth factor for epithelial cells. Int J Cancer (2005) 1.35
Circulating levels of 25-hydroxyvitamin D and human cathelicidin in healthy adults. J Allergy Clin Immunol (2011) 1.35
Mast cells regulate homeostatic intestinal epithelial migration and barrier function by a chymase/Mcpt4-dependent mechanism. Proc Natl Acad Sci U S A (2009) 1.34
Induction of neutrophil gelatinase-associated lipocalin expression by co-stimulation with interleukin-17 and tumor necrosis factor-alpha is controlled by IkappaB-zeta but neither by C/EBP-beta nor C/EBP-delta. J Biol Chem (2010) 1.34
Serglycin is essential for maturation of mast cell secretory granule. J Biol Chem (2004) 1.32
The transcriptional activation program of human neutrophils in skin lesions supports their important role in wound healing. J Immunol (2004) 1.31
The in vivo profile of transcription factors during neutrophil differentiation in human bone marrow. Blood (2003) 1.30
Independent degeneration of photoreceptors and retinal pigment epithelium in conditional knockout mouse models of choroideremia. J Clin Invest (2006) 1.29
The affinity of the FimH fimbrial adhesin is receptor-driven and quasi-independent of Escherichia coli pathotypes. Mol Microbiol (2006) 1.28
Statin-sensitive endocytosis of albumin by glomerular podocytes. Am J Physiol Renal Physiol (2006) 1.27
Haptoglobin is synthesized during granulocyte differentiation, stored in specific granules, and released by neutrophils in response to activation. Blood (2006) 1.27
Arginase 1 is expressed in myelocytes/metamyelocytes and localized in gelatinase granules of human neutrophils. Blood (2007) 1.26
Amnionless function is required for cubilin brush-border expression and intrinsic factor-cobalamin (vitamin B12) absorption in vivo. Blood (2005) 1.25
Intracellular proteoglycans. Biochem J (2004) 1.25
Resolving the energy paradox of chaperone/usher-mediated fibre assembly. Biochem J (2005) 1.25
Phospholipid flip-flop and phospholipid scramblase 1 (PLSCR1) co-localize to uropod rafts in formylated Met-Leu-Phe-stimulated neutrophils. J Biol Chem (2004) 1.24
Neurotensin increases mortality and mast cells reduce neurotensin levels in a mouse model of sepsis. Nat Med (2008) 1.23
Lipocalin 2 deficiency dysregulates iron homeostasis and exacerbates endotoxin-induced sepsis. J Immunol (2012) 1.22
Rab27b regulates mast cell granule dynamics and secretion. Traffic (2007) 1.22
Endocytosis provides a major alternative pathway for lysosomal biogenesis in kidney proximal tubular cells. Proc Natl Acad Sci U S A (2007) 1.21
Megalin and cubilin are endocytic receptors involved in renal clearance of hemoglobin. J Am Soc Nephrol (2002) 1.21
ZONAB promotes proliferation and represses differentiation of proximal tubule epithelial cells. J Am Soc Nephrol (2010) 1.20
A tick salivary protein targets cathepsin G and chymase and inhibits host inflammation and platelet aggregation. Blood (2010) 1.20
Neutrophil extracellular traps - the dark side of neutrophils. J Clin Invest (2016) 1.19
Lipocalin 2 is protective against E. coli pneumonia. Respir Res (2010) 1.19
The innate pattern recognition molecule Ficolin-1 is secreted by monocytes/macrophages and is circulating in human plasma. Mol Immunol (2008) 1.18
On mouse and man: neutrophil gelatinase associated lipocalin is not involved in apoptosis or acute response. Eur J Haematol (2005) 1.17
Three-dimensional reconstruction of the mouse nephron. J Am Soc Nephrol (2005) 1.17
Mast cell chymase reduces the toxicity of Gila monster venom, scorpion venom, and vasoactive intestinal polypeptide in mice. J Clin Invest (2011) 1.16
Receptor-mediated endocytosis of α-galactosidase A in human podocytes in Fabry disease. PLoS One (2011) 1.15
Mouse mast cell protease 4 is the major chymase in murine airways and has a protective role in allergic airway inflammation. J Immunol (2009) 1.15
Olfactomedin 4 defines a subset of human neutrophils. J Leukoc Biol (2011) 1.15
Feasibility, physical capacity, and health benefits of a multidimensional exercise program for cancer patients undergoing chemotherapy. Support Care Cancer (2003) 1.14
Defensin-rich granules of human neutrophils: characterization of secretory properties. Biochim Biophys Acta (2002) 1.14
Systems biology of neutrophil differentiation and immune response. Curr Opin Immunol (2005) 1.14
Neutrophil gelatinase-associated lipocalin is a marker for dysregulated keratinocyte differentiation in human skin. Exp Dermatol (2002) 1.14
The αvβ6 integrin modulates airway hyperresponsiveness in mice by regulating intraepithelial mast cells. J Clin Invest (2012) 1.13
Transforming growth factor-beta1 reduces megalin- and cubilin-mediated endocytosis of albumin in proximal-tubule-derived opossum kidney cells. J Physiol (2003) 1.13
The genetics of ficolins. J Innate Immun (2009) 1.12
Increased levels of hypoxia-sensitive proteins in allergic airway inflammation. Am J Respir Crit Care Med (2004) 1.11
Serglycin: a structural and functional chameleon with wide impact on immune cells. J Immunol (2011) 1.11
A patient with cubilin deficiency. N Engl J Med (2011) 1.10
Cysteine-rich secretory protein 3 is a ligand of alpha1B-glycoprotein in human plasma. Biochemistry (2004) 1.10
Serglycin-deficient cytotoxic T lymphocytes display defective secretory granule maturation and granzyme B storage. J Biol Chem (2005) 1.09
Comparing cancer vs normal gene expression profiles identifies new disease entities and common transcriptional programs in AML patients. Blood (2013) 1.09
Proteome profiling of human neutrophil granule subsets, secretory vesicles, and cell membrane: correlation with transcriptome profiling of neutrophil precursors. J Leukoc Biol (2013) 1.09
Localization of serglycin in human neutrophil granulocytes and their precursors. J Leukoc Biol (2004) 1.09
Megalin and cubilin--the story of two multipurpose receptors unfolds. Nephrol Dial Transplant (2002) 1.09
Identification of human cysteine-rich secretory protein 3 (CRISP-3) as a matrix protein in a subset of peroxidase-negative granules of neutrophils and in the granules of eosinophils. J Leukoc Biol (2002) 1.07
beta-Microseminoprotein binds CRISP-3 in human seminal plasma. Biochem Biophys Res Commun (2005) 1.07