Supramolecular design of self-assembling nanofibers for cartilage regeneration.

PubWeight™: 1.95‹?› | Rank: Top 2%

🔗 View Article (PMC 2840471)

Published in Proc Natl Acad Sci U S A on February 01, 2010

Authors

Ramille N Shah1, Nirav A Shah, Marc M Del Rosario Lim, Caleb Hsieh, Gordon Nuber, Samuel I Stupp

Author Affiliations

1: Institute for BioNanotechnology in Medicine, Northwestern University, Chicago, IL 60611, USA.

Articles citing this

Functional supramolecular polymers. Science (2012) 3.16

Moving from static to dynamic complexity in hydrogel design. Nat Commun (2012) 1.40

Self-assembling peptide scaffolds for regenerative medicine. Chem Commun (Camb) (2011) 1.38

Hydrogels for the repair of articular cartilage defects. Tissue Eng Part B Rev (2011) 1.35

Tissue engineering and regenerative medicine: recent innovations and the transition to translation. Tissue Eng Part B Rev (2013) 1.34

Antitumor activity of peptide amphiphile nanofiber-encapsulated camptothecin. ACS Nano (2011) 1.22

Peptide Self-Assembly for Crafting Functional Biological Materials. Curr Opin Solid State Mater Sci (2011) 1.22

Regeneration of the cavernous nerve by Sonic hedgehog using aligned peptide amphiphile nanofibers. Biomaterials (2010) 1.18

25th anniversary article: supramolecular materials for regenerative medicine. Adv Mater (2014) 1.17

Bone regeneration with low dose BMP-2 amplified by biomimetic supramolecular nanofibers within collagen scaffolds. Biomaterials (2012) 1.15

Multi-component extracellular matrices based on peptide self-assembly. Chem Soc Rev (2010) 1.10

Programmable shape-shifting micelles. Angew Chem Int Ed Engl (2010) 1.10

A bioactive self-assembled membrane to promote angiogenesis. Biomaterials (2010) 1.07

Controlled release of dexamethasone from peptide nanofiber gels to modulate inflammatory response. Biomaterials (2012) 1.05

A multimaterial bioink method for 3D printing tunable, cell-compatible hydrogels. Adv Mater (2015) 1.04

The effect of nanofiber-guided cell alignment on the preferential differentiation of neural stem cells. Biomaterials (2010) 1.03

Smart self-assembled hybrid hydrogel biomaterials. Angew Chem Int Ed Engl (2012) 1.03

Drug release from hydrazone-containing peptide amphiphiles. Chem Commun (Camb) (2011) 1.02

Supramolecular biomaterials. Nat Mater (2015) 1.02

Self-assembly of biomolecular soft matter. Faraday Discuss (2013) 0.99

A hybrid nanofiber matrix to control the survival and maturation of brain neurons. Biomaterials (2011) 0.99

Self-assembly and biomaterials. Nano Lett (2010) 0.99

Switching of Self-Assembly in a Peptide Nanostructure with a Specific Enzyme. Soft Matter (2011) 0.98

Coassembled cytotoxic and pegylated peptide amphiphiles form filamentous nanostructures with potent antitumor activity in models of breast cancer. ACS Nano (2012) 0.97

Photodynamic control of bioactivity in a nanofiber matrix. ACS Nano (2012) 0.97

Molecular nanofibers of olsalazine form supramolecular hydrogels for reductive release of an anti-inflammatory agent. J Am Chem Soc (2010) 0.96

Tuning supramolecular mechanics to guide neuron development. Biomaterials (2013) 0.95

Peptide hydrogelation and cell encapsulation for 3D culture of MCF-7 breast cancer cells. PLoS One (2013) 0.95

Self-Assembly for the Synthesis of Functional Biomaterials. Acta Mater (2013) 0.93

Nanostructure-templated control of drug release from peptide amphiphile nanofiber gels. Soft Matter (2012) 0.91

Peptide amphiphile nanofiber delivery of sonic hedgehog protein to reduce smooth muscle apoptosis in the penis after cavernous nerve resection. J Sex Med (2010) 0.90

Nanoscale tissue engineering: spatial control over cell-materials interactions. Nanotechnology (2011) 0.90

Gel scaffolds of BMP-2-binding peptide amphiphile nanofibers for spinal arthrodesis. Adv Healthc Mater (2014) 0.89

The role of nanoscale architecture in supramolecular templating of biomimetic hydroxyapatite mineralization. Small (2012) 0.87

Design of growth factor sequestering biomaterials. Chem Commun (Camb) (2014) 0.87

A novel family of biodegradable poly(ester amide) elastomers. Adv Mater (2011) 0.86

Tubular hydrogels of circumferentially aligned nanofibers to encapsulate and orient vascular cells. Biomaterials (2012) 0.85

Strategies for controlled delivery of biologics for cartilage repair. Adv Drug Deliv Rev (2014) 0.85

Self-assembling glucagon-like peptide 1-mimetic peptide amphiphiles for enhanced activity and proliferation of insulin-secreting cells. Acta Biomater (2012) 0.83

Functionalized nanostructures with application in regenerative medicine. Int J Mol Sci (2012) 0.83

Self-delivery multifunctional anti-HIV hydrogels for sustained release. Adv Healthc Mater (2013) 0.83

Self-assembly of cytotoxic peptide amphiphiles into supramolecular membranes for cancer therapy. Adv Healthc Mater (2012) 0.83

Bioactive DNA-peptide nanotubes enhance the differentiation of neural stem cells into neurons. Nano Lett (2014) 0.81

A Peptide-Based Material for Therapeutic Carbon Monoxide Delivery. Soft Matter (2012) 0.81

Post-assembly functionalization of supramolecular nanostructures with bioactive peptides and fluorescent proteins by native chemical ligation. Bioconjug Chem (2014) 0.81

Combinatorial screening of chemically defined human mesenchymal stem cell culture substrates. J Mater Chem (2012) 0.81

Gd(III)-labeled peptide nanofibers for reporting on biomaterial localization in vivo. ACS Nano (2014) 0.81

Three-Dimensional Cell Entrapment as a Function of the Weight Percent of Peptide-Amphiphile Hydrogels. Langmuir (2015) 0.80

Self-assembling amphiphilic peptides. J Pept Sci (2014) 0.80

Advances in cryogenic transmission electron microscopy for the characterization of dynamic self-assembling nanostructures. Curr Opin Colloid Interface Sci (2012) 0.79

Generation of Chimeric "ABS Nanohemostat" Complex and Comparing Its Histomorphological In Vivo Effects to the Traditional Ankaferd Hemostat in Controlled Experimental Partial Nephrectomy Model. Int J Biomater (2013) 0.79

Esterase-activated release of naproxen from supramolecular nanofibres. Chem Commun (Camb) (2014) 0.79

Skeletal tissue regeneration: where can hydrogels play a role? Int Orthop (2014) 0.78

Modulation of chondrocyte behavior through tailoring functional synthetic saccharide-peptide hydrogels. Biomaterials (2012) 0.77

Model-driven optimization of multicomponent self-assembly processes. Proc Natl Acad Sci U S A (2013) 0.77

Biopolymers and supramolecular polymers as biomaterials for biomedical applications. MRS Bull (2015) 0.77

Biomaterials for tissue engineering. Ann Biomed Eng (2013) 0.77

Electrospinning bioactive supramolecular polymers from water. Biomacromolecules (2014) 0.76

Peptide Amphiphiles in Corneal Tissue Engineering. J Funct Biomater (2015) 0.76

Fibrous Scaffolds with Varied Fiber Chemistry and Growth Factor Delivery Promote Repair in a Porcine Cartilage Defect Model. Tissue Eng Part A (2015) 0.76

Glutathione-triggered formation of a Fmoc-protected short peptide-based supramolecular hydrogel. PLoS One (2014) 0.76

Role of Nanotechnology in Erectile Dysfunction Treatment. J Sex Med (2017) 0.75

Harnessing supramolecular peptide nanotechnology in biomedical applications. Int J Nanomedicine (2017) 0.75

Preparation of a novel composite nanofiber gel-encapsulated human placental extract through layer-by-layer self-assembly. Exp Ther Med (2016) 0.75

Fragmentation and Coagulation in Supramolecular (Co)polymerization Kinetics. ACS Cent Sci (2016) 0.75

Rational design of fiber forming supramolecular structures. Exp Biol Med (Maywood) (2016) 0.75

Self-assembling peptides for stem cell and tissue engineering. Biomater Sci (2016) 0.75

Advancing musculoskeletal research with nanoscience. Nat Rev Rheumatol (2013) 0.75

Supramolecular Nanofibers Enhance Growth Factor Signaling by Increasing Lipid Raft Mobility. Nano Lett (2016) 0.75

Separation, immobilization, and biocatalytic utilization of proteins by a supramolecular membrane. PLoS One (2013) 0.75

Aloe Vera for Tissue Engineering Applications. J Funct Biomater (2017) 0.75

Towards the sequence-specific multivalent molecular recognition of cyclodextrin oligomers. Beilstein J Org Chem (2014) 0.75

Enhanced potency of cell-based therapy for ischemic tissue repair using an injectable bioactive epitope presenting nanofiber support matrix. J Mol Cell Cardiol (2014) 0.75

Epitope topography controls bioactivity in supramolecular nanofibers. Biomater Sci (2015) 0.75

Peptide hormones and lipopeptides: from self-assembly to therapeutic applications. J Pept Sci (2017) 0.75

Mimicking the Bioactivity of Fibroblast Growth Factor-2 Using Supramolecular Nanoribbons. ACS Biomater Sci Eng (2017) 0.75

In vitro and in vivo studies of a novel bacterial cellulose-based acellular bilayer nanocomposite scaffold for the repair of osteochondral defects. Int J Nanomedicine (2017) 0.75

Articles cited by this

Self-assembly and mineralization of peptide-amphiphile nanofibers. Science (2001) 8.90

In vitro chondrogenesis of bone marrow-derived mesenchymal progenitor cells. Exp Cell Res (1998) 8.24

Articular cartilage repair: basic science and clinical progress. A review of the current status and prospects. Osteoarthritis Cartilage (2002) 5.64

Phage Display. Chem Rev (1997) 4.57

Peptide-amphiphile nanofibers: a versatile scaffold for the preparation of self-assembling materials. Proc Natl Acad Sci U S A (2002) 3.96

Articular cartilage: degeneration and osteoarthritis, repair, regeneration, and transplantation. Instr Course Lect (1998) 3.27

Heparin binding nanostructures to promote growth of blood vessels. Nano Lett (2006) 2.65

Results after microfracture of full-thickness chondral defects in different compartments in the knee. Osteoarthritis Cartilage (2006) 2.13

In vivo engineering of organs: the bone bioreactor. Proc Natl Acad Sci U S A (2005) 2.04

Early events in cartilage repair after subchondral bone microfracture. Clin Orthop Relat Res (2003) 1.97

Transforming growth factor beta type 1 binds to collagen IV of basement membrane matrix: implications for development. Dev Biol (1991) 1.87

The healing and regeneration of articular cartilage. J Bone Joint Surg Am (1998) 1.82

The chondrogenic potential of free autogenous periosteal grafts for biological resurfacing of major full-thickness defects in joint surfaces under the influence of continuous passive motion. An experimental investigation in the rabbit. J Bone Joint Surg Am (1986) 1.74

Coassembly of amphiphiles with opposite peptide polarities into nanofibers. J Am Chem Soc (2005) 1.72

Microfracture: indications, technique, and results. Instr Course Lect (2007) 1.33

Healing of canine articular cartilage defects treated with microfracture, a type-II collagen matrix, or cultured autologous chondrocytes. J Orthop Res (2000) 1.30

Symptomatic articular cartilage degeneration: the impact in the new millennium. Clin Orthop Relat Res (2001) 1.28

Protein design and phage display. Chem Rev (2001) 1.20

The transforming growth factor-betas: multifaceted regulators of the development and maintenance of skeletal muscles, motoneurons and Schwann cells. Int J Dev Biol (2002) 1.15

Growth-factor-induced healing of partial-thickness defects in adult articular cartilage. Osteoarthritis Cartilage (2001) 1.14

Mediators of angiogenesis: the biological significance of basic fibroblast growth factor (bFGF)-heparin and heparan sulfate interactions. Semin Cancer Biol (1992) 1.14

Aqueous self-assembly of unsymmetric Peptide bolaamphiphiles into nanofibers with hydrophilic cores and surfaces. J Am Chem Soc (2003) 0.99

Chondrogenic phenotype of perichondrium-derived chondroprogenitor cells is influenced by transforming growth factor-beta 1. J Orthop Res (1997) 0.86

The use of growth factors in cartilage repair. Orthop Clin North Am (2000) 0.86

Articles by these authors

(truncated to the top 100)

Selective differentiation of neural progenitor cells by high-epitope density nanofibers. Science (2004) 6.38

Peptide-amphiphile nanofibers: a versatile scaffold for the preparation of self-assembling materials. Proc Natl Acad Sci U S A (2002) 3.96

Sorting carbon nanotubes by electronic structure using density differentiation. Nat Nanotechnol (2006) 3.66

Self-assembly of peptide amphiphiles: from molecules to nanostructures to biomaterials. Biopolymers (2010) 2.86

Self-assembling nanofibers inhibit glial scar formation and promote axon elongation after spinal cord injury. J Neurosci (2008) 2.79

Heparin binding nanostructures to promote growth of blood vessels. Nano Lett (2006) 2.65

Self-assembly of large and small molecules into hierarchically ordered sacs and membranes. Science (2008) 2.52

A self-assembly pathway to aligned monodomain gels. Nat Mater (2010) 2.01

Biomimetic systems for hydroxyapatite mineralization inspired by bone and enamel. Chem Rev (2008) 1.96

Coassembly of amphiphiles with opposite peptide polarities into nanofibers. J Am Chem Soc (2005) 1.72

Self-assembling peptide amphiphile nanofiber matrices for cell entrapment. Acta Biomater (2005) 1.68

Supramolecular crafting of cell adhesion. Biomaterials (2007) 1.66

Self-assembled peptide amphiphile nanofibers conjugated to MRI contrast agents. Nano Lett (2005) 1.59

Development of bioactive peptide amphiphiles for therapeutic cell delivery. Acta Biomater (2009) 1.57

Self-assembly combining two bioactive peptide-amphiphile molecules into nanofibers by electrostatic attraction. J Am Chem Soc (2003) 1.54

Molecular self-assembly into one-dimensional nanostructures. Acc Chem Res (2008) 1.53

Hydrodynamic characterization of surfactant encapsulated carbon nanotubes using an analytical ultracentrifuge. ACS Nano (2008) 1.53

Enrichment of single-walled carbon nanotubes by diameter in density gradients. Nano Lett (2005) 1.51

Supramolecular nanostructures that mimic VEGF as a strategy for ischemic tissue repair. Proc Natl Acad Sci U S A (2011) 1.50

Presentation of RGDS epitopes on self-assembled nanofibers of branched peptide amphiphiles. Biomacromolecules (2006) 1.48

Nitric oxide and nanotechnology: a novel approach to inhibit neointimal hyperplasia. J Vasc Surg (2008) 1.47

Hybrid bone implants: self-assembly of peptide amphiphile nanofibers within porous titanium. Biomaterials (2007) 1.44

Bone regeneration mediated by biomimetic mineralization of a nanofiber matrix. Biomaterials (2010) 1.43

Molecular simulation study of peptide amphiphile self-assembly. J Phys Chem B (2008) 1.42

Bioactive nanofibers instruct cells to proliferate and differentiate during enamel regeneration. J Bone Miner Res (2008) 1.42

Spontaneous and x-ray-triggered crystallization at long range in self-assembling filament networks. Science (2009) 1.42

Tuning supramolecular rigidity of peptide fibers through molecular structure. J Am Chem Soc (2010) 1.38

Self-assembling peptide scaffolds for regenerative medicine. Chem Commun (Camb) (2011) 1.38

Extracellular matrix in pancreatic islets: relevance to scaffold design and transplantation. Cell Transplant (2009) 1.35

Induction of cancer cell death by self-assembling nanostructures incorporating a cytotoxic peptide. Cancer Res (2010) 1.32

Self-assembly of giant peptide nanobelts. Nano Lett (2009) 1.30

Magnetic resonance imaging of self-assembled biomaterial scaffolds. Bioconjug Chem (2005) 1.29

BMPR1a and BMPR1b signaling exert opposing effects on gliosis after spinal cord injury. J Neurosci (2010) 1.29

Direct observation of morphological transformation from twisted ribbons into helical ribbons. J Am Chem Soc (2010) 1.25

Peptide amphiphile nanostructure-heparin interactions and their relationship to bioactivity. Biomaterials (2008) 1.24

Capturing the stem cell paracrine effect using heparin-presenting nanofibres to treat cardiovascular diseases. J Tissue Eng Regen Med (2010) 1.23

Enzyme Directed Templating of Artificial Bone Mineral. Adv Mater (2009) 1.23

Antitumor activity of peptide amphiphile nanofiber-encapsulated camptothecin. ACS Nano (2011) 1.22

Peptide Self-Assembly for Crafting Functional Biological Materials. Curr Opin Solid State Mater Sci (2011) 1.22

Light-triggered bioactivity in three dimensions. Angew Chem Int Ed Engl (2009) 1.21

Dynamic in vivo biocompatibility of angiogenic peptide amphiphile nanofibers. Biomaterials (2009) 1.20

Growth factor delivery from self-assembling nanofibers to facilitate islet transplantation. Transplantation (2008) 1.20

A synergistic assembly of nanoscale lamellar photoconductor hybrids. Nat Mater (2008) 1.19

Probing the interior of peptide amphiphile supramolecular aggregates. J Am Chem Soc (2005) 1.19

Regeneration of the cavernous nerve by Sonic hedgehog using aligned peptide amphiphile nanofibers. Biomaterials (2010) 1.18

Branched peptide-amphiphiles as self-assembling coatings for tissue engineering scaffolds. J Biomed Mater Res A (2006) 1.18

25th anniversary article: supramolecular materials for regenerative medicine. Adv Mater (2014) 1.17

Room-temperature ferroelectricity in supramolecular networks of charge-transfer complexes. Nature (2012) 1.16

Supramolecular self-assembly codes for functional structures. Philos Trans A Math Phys Eng Sci (2007) 1.16

The powerful functions of peptide-based bioactive matrices for regenerative medicine. Ann Biomed Eng (2014) 1.15

Bone regeneration with low dose BMP-2 amplified by biomimetic supramolecular nanofibers within collagen scaffolds. Biomaterials (2012) 1.15

Self-assembling biomaterials: liquid crystal phases of cholesteryl oligo(L-lactic acid) and their interactions with cells. Proc Natl Acad Sci U S A (2002) 1.12

Presentation and recognition of biotin on nanofibers formed by branched peptide amphiphiles. Nano Lett (2005) 1.12

Tunable mechanics of peptide nanofiber gels. Langmuir (2010) 1.11

A naphthodithiophene-diketopyrrolopyrrole donor molecule for efficient solution-processed solar cells. J Am Chem Soc (2011) 1.09

Self-assembling nanostructures to deliver angiogenic factors to pancreatic islets. Biomaterials (2010) 1.09

Quadruple helix formation of a photoresponsive peptide amphiphile and its light-triggered dissociation into single fibers. J Am Chem Soc (2008) 1.09

Evaluation of the tissue reaction to a new bilayered collagen matrix in vivo and its translation to the clinic. Biomed Mater (2011) 1.08

A bioactive self-assembled membrane to promote angiogenesis. Biomaterials (2010) 1.07

Biological synthesis of tooth enamel instructed by an artificial matrix. Biomaterials (2010) 1.06

Aligned neurite outgrowth and directed cell migration in self-assembled monodomain gels. Biomaterials (2013) 1.06

Electrostatic control of bioactivity. Angew Chem Int Ed Engl (2011) 1.05

Controlled release of dexamethasone from peptide nanofiber gels to modulate inflammatory response. Biomaterials (2012) 1.05

Covalent functionalization of NiTi surfaces with bioactive peptide amphiphile nanofibers. Biomaterials (2008) 1.03

Encapsulation of carbon nanotubes by self-assembling peptide amphiphiles. Langmuir (2005) 1.03

A bioactive titanium foam scaffold for bone repair. Acta Biomater (2005) 1.03

Atomistic molecular dynamics simulations of peptide amphiphile self-assembly into cylindrical nanofibers. J Am Chem Soc (2011) 1.02

Semiconductor nanohelices templated by supramolecular ribbons. Angew Chem Int Ed Engl (2002) 1.02

A templating approach for monodisperse self-assembled organic nanostructures. J Am Chem Soc (2008) 1.02

Drug release from hydrazone-containing peptide amphiphiles. Chem Commun (Camb) (2011) 1.02

Micropatterning of bioactive self-assembling gels. Soft Matter (2009) 1.01

Biomechanical and histological evaluation of osteochondral transplantation in a rabbit model. Am J Sports Med (2004) 1.00

Synthesis, self-assembly, and characterization of supramolecular polymers from electroactive dendron rodcoil molecules. J Am Chem Soc (2004) 1.00

Aqueous self-assembly of unsymmetric Peptide bolaamphiphiles into nanofibers with hydrophilic cores and surfaces. J Am Chem Soc (2003) 0.99

A hybrid nanofiber matrix to control the survival and maturation of brain neurons. Biomaterials (2011) 0.99

Titanium foam-bioactive nanofiber hybrids for bone regeneration. J Tissue Eng Regen Med (2008) 0.99

Molecular crystallization controlled by pH regulates mesoscopic membrane morphology. ACS Nano (2012) 0.99

Self-assembly of biomolecular soft matter. Faraday Discuss (2013) 0.99

Modulation of fluorescence through coassembly of molecules in organic nanostructures. J Am Chem Soc (2007) 0.98

Modification of gelation kinetics in bioactive peptide amphiphiles. Biomaterials (2008) 0.98

Switching of Self-Assembly in a Peptide Nanostructure with a Specific Enzyme. Soft Matter (2011) 0.98

Coassembled cytotoxic and pegylated peptide amphiphiles form filamentous nanostructures with potent antitumor activity in models of breast cancer. ACS Nano (2012) 0.97

Simultaneous self-assembly, orientation, and patterning of peptide-amphiphile nanofibers by soft lithography. Nano Lett (2007) 0.97

Dynamic display of bioactivity through host-guest chemistry. Angew Chem Int Ed Engl (2013) 0.97

Photodynamic control of bioactivity in a nanofiber matrix. ACS Nano (2012) 0.97

Pathway selection in peptide amphiphile assembly. J Am Chem Soc (2014) 0.96

Tuning supramolecular mechanics to guide neuron development. Biomaterials (2013) 0.95

Peptide amphiphile nanofibers with conjugated polydiacetylene backbones in their core. J Am Chem Soc (2008) 0.95

Self-assembling peptide amphiphile promotes plasticity of serotonergic fibers following spinal cord injury. J Neurosci Res (2010) 0.95

Light-induced self-assembly of nanofibers inside liposomes. Soft Matter (2008) 0.95

Surfactant-free water-processable photoconductive all-carbon composite. J Am Chem Soc (2011) 0.94

Self-Assembly for the Synthesis of Functional Biomaterials. Acta Mater (2013) 0.93

Cellular response to zinc-containing organoapatite: an in vitro study of proliferation, alkaline phosphatase activity and biomineralization. Biomaterials (2005) 0.93

Biomechanical analysis of bursal-sided partial thickness rotator cuff tears. J Shoulder Elbow Surg (2009) 0.91

Nanostructure-templated control of drug release from peptide amphiphile nanofiber gels. Soft Matter (2012) 0.91

Long-range ordering of highly charged self-assembled nanofilaments. J Am Chem Soc (2014) 0.91

Peptide amphiphile nanofiber delivery of sonic hedgehog protein to reduce smooth muscle apoptosis in the penis after cavernous nerve resection. J Sex Med (2010) 0.90

Amino acid sequence in constitutionally isomeric tetrapeptide amphiphiles dictates architecture of one-dimensional nanostructures. J Am Chem Soc (2014) 0.90

Interfacial self-assembly of cell-like filamentous microcapsules. Angew Chem Int Ed Engl (2011) 0.89

A torsional strain mechanism to tune pitch in supramolecular helices. Angew Chem Int Ed Engl (2007) 0.89