PubRank

Gabriel A Rabinovich

Author PubWeight™ 113.51‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Galectins as modulators of tumour progression. Nat Rev Cancer 2005 5.30
2 Differential glycosylation of TH1, TH2 and TH-17 effector cells selectively regulates susceptibility to cell death. Nat Immunol 2007 3.07
3 Protein-glycan interactions in the control of innate and adaptive immune responses. Nat Immunol 2008 2.77
4 Galectins: structure, function and therapeutic potential. Expert Rev Mol Med 2008 2.61
5 Targeted inhibition of galectin-1 gene expression in tumor cells results in heightened T cell-mediated rejection; A potential mechanism of tumor-immune privilege. Cancer Cell 2004 2.46
6 A comparative study of the anti-inflammatory, anticoagulant, antiangiogenic, and antiadhesive activities of nine different fucoidans from brown seaweeds. Glycobiology 2007 2.45
7 The AP1-dependent secretion of galectin-1 by Reed Sternberg cells fosters immune privilege in classical Hodgkin lymphoma. Proc Natl Acad Sci U S A 2007 2.31
8 Tolerogenic signals delivered by dendritic cells to T cells through a galectin-1-driven immunoregulatory circuit involving interleukin 27 and interleukin 10. Nat Immunol 2009 2.23
9 Galectin-1 deactivates classically activated microglia and protects from inflammation-induced neurodegeneration. Immunity 2012 2.18
10 A pivotal role for galectin-1 in fetomaternal tolerance. Nat Med 2007 2.08
11 Galectins: regulators of acute and chronic inflammation. Ann N Y Acad Sci 2010 1.83
12 A unique galectin signature in human prostate cancer progression suggests galectin-1 as a key target for treatment of advanced disease. Cancer Res 2012 1.74
13 Viral induction and targeted inhibition of galectin-1 in EBV+ posttransplant lymphoproliferative disorders. Blood 2011 1.53
14 A novel function for galectin-1 at the crossroad of innate and adaptive immunity: galectin-1 regulates monocyte/macrophage physiology through a nonapoptotic ERK-dependent pathway. J Immunol 2007 1.46
15 Targeting galectin-1 overcomes breast cancer-associated immunosuppression and prevents metastatic disease. Cancer Res 2012 1.44
16 Galectin-1 suppresses experimental colitis in mice. Gastroenterology 2003 1.41
17 Galectin-1 suppresses autoimmune retinal disease by promoting concomitant Th2- and T regulatory-mediated anti-inflammatory responses. J Immunol 2006 1.37
18 When galectins recognize glycans: from biochemistry to physiology and back again. Biochemistry 2011 1.34
19 Disrupting galectin-1 interactions with N-glycans suppresses hypoxia-driven angiogenesis and tumorigenesis in Kaposi's sarcoma. J Exp Med 2012 1.31
20 Galectin-3 mediates IL-4-induced survival and differentiation of B cells: functional cross-talk and implications during Trypanosoma cruzi infection. J Immunol 2004 1.24
21 Dynamic cross-talk between tumor and immune cells in orchestrating the immunosuppressive network at the tumor microenvironment. Cancer Immunol Immunother 2007 1.21
22 NF-kappa B regulates expression of the MHC class I-related chain A gene in activated T lymphocytes. J Immunol 2004 1.20
23 Tolerance signaling molecules and pregnancy: IDO, galectins, and the renaissance of regulatory T cells. Am J Reprod Immunol 2007 1.20
24 Galectin-3 and soluble fibrinogen act in concert to modulate neutrophil activation and survival: involvement of alternative MAPK pathways. Glycobiology 2004 1.18
25 Intracellular retention of the NKG2D ligand MHC class I chain-related gene A in human melanomas confers immune privilege and prevents NK cell-mediated cytotoxicity. J Immunol 2008 1.17
26 Galectin-1 sensitizes resting human T lymphocytes to Fas (CD95)-mediated cell death via mitochondrial hyperpolarization, budding, and fission. J Biol Chem 2004 1.17
27 AP1-dependent galectin-1 expression delineates classical hodgkin and anaplastic large cell lymphomas from other lymphoid malignancies with shared molecular features. Clin Cancer Res 2008 1.11
28 Control of dendritic cell maturation and function by triiodothyronine. FASEB J 2007 1.06
29 Fucans, but not fucomannoglucuronans, determine the biological activities of sulfated polysaccharides from Laminaria saccharina brown seaweed. PLoS One 2011 1.05
30 Silencing survivin gene expression promotes apoptosis of human breast cancer cells through a caspase-independent pathway. J Cell Biochem 2008 1.05
31 Neuroblastoma triggers an immunoevasive program involving galectin-1-dependent modulation of T cell and dendritic cell compartments. Int J Cancer 2011 1.03
32 Histone deacetylase inhibitors impair NK cell viability and effector functions through inhibition of activation and receptor expression. J Leukoc Biol 2011 1.02
33 Galectin 3 induces a distinctive pattern of cytokine and chemokine production in rheumatoid synovial fibroblasts via selective signaling pathways. Arthritis Rheum 2009 1.02
34 Activation-induced expression of MICA on T lymphocytes involves engagement of CD3 and CD28. J Leukoc Biol 2002 1.01
35 Endogenous lectins shape the function of dendritic cells and tailor adaptive immunity: mechanisms and biomedical applications. Int Immunopharmacol 2011 1.01
36 Modulation of endothelial cell migration and angiogenesis: a novel function for the "tandem-repeat" lectin galectin-8. FASEB J 2010 0.98
37 Galectin-1 expression in human glioma cells: modulation by ionizing radiation and effects on tumor cell proliferation and migration. Oncol Rep 2007 0.97
38 Synthetic inhibitors of galectin-1 and -3 selectively modulate homotypic cell aggregation and tumor cell apoptosis. Anticancer Res 2009 0.96
39 Multiple functional targets of the immunoregulatory activity of galectin-1: Control of immune cell trafficking, dendritic cell physiology, and T-cell fate. Methods Enzymol 2010 0.96
40 Vascular galectins: regulators of tumor progression and targets for cancer therapy. Cytokine Growth Factor Rev 2013 0.95
41 Galectin-1 as a potential therapeutic target in autoimmune disorders and cancer. Expert Opin Biol Ther 2008 0.95
42 Proteomic analysis identifies galectin-1 as a predictive biomarker for relapsed/refractory disease in classical Hodgkin lymphoma. Blood 2011 0.95
43 Apoptosis resistance in HIV-1 persistently-infected cells is independent of active viral replication and involves modulation of the apoptotic mitochondrial pathway. Retrovirology 2008 0.95
44 Nuclear factor (NF)-kappaB-dependent thyroid hormone receptor beta1 expression controls dendritic cell function via Akt signaling. J Biol Chem 2009 0.93
45 Opposite effects of galectin-1 on alternative metabolic pathways of L-arginine in resident, inflammatory, and activated macrophages. Glycobiology 2002 0.93
46 Novel roles of galectin-1 in hepatocellular carcinoma cell adhesion, polarization, and in vivo tumor growth. Hepatology 2011 0.92
47 Expanding the universe of cytokines and pattern recognition receptors: galectins and glycans in innate immunity. J Clin Immunol 2010 0.92
48 Coupling pathogen recognition to innate immunity through glycan-dependent mechanisms. Int Immunopharmacol 2011 0.91
49 The immunoregulatory glycan-binding protein galectin-1 triggers human platelet activation. FASEB J 2007 0.91
50 Bone-specific antibodies in sera from patients with celiac disease: characterization and implications in osteoporosis. J Clin Immunol 2002 0.90
51 Regulated expression of galectin-3, a multifunctional glycan-binding protein, in haematopoietic and non-haematopoietic tissues. Histol Histopathol 2011 0.90
52 Dissecting the pathophysiologic role of endogenous lectins: glycan-binding proteins with cytokine-like activity? Cytokine Growth Factor Rev 2007 0.90
53 Regulated expression and ultrastructural localization of galectin-1, a proapoptotic beta-galactoside-binding lectin, during spermatogenesis in rat testis. Biol Reprod 2003 0.90
54 Tolerogenic dendritic cells in the control of autoimmune neuroinflammation: an emerging role of protein-glycan interactions. Neuroimmunomodulation 2010 0.89
55 Overcoming the hurdles of tumor immunity by targeting regulatory pathways in innate and adaptive immune cells. Curr Pharm Des 2010 0.88
56 Characterization and functionality of proliferative human Sertoli cells. Cell Transplant 2010 0.88
57 Regulation of galectin-1 expression by transforming growth factor beta1 in metastatic mammary adenocarcinoma cells: implications for tumor-immune escape. Cancer Immunol Immunother 2006 0.87
58 Administration of a peptide inhibitor of alpha4-integrin inhibits the development of experimental autoimmune uveitis. Invest Ophthalmol Vis Sci 2005 0.87
59 Nuclear factor (NF)-κB controls expression of the immunoregulatory glycan-binding protein galectin-1. Mol Immunol 2011 0.87
60 Tumour-experienced T cells promote NK cell activity through trogocytosis of NKG2D and NKp46 ligands. EMBO Rep 2009 0.86
61 Dexamethasone counteracts the immunostimulatory effects of triiodothyronine (T3) on dendritic cells. Steroids 2011 0.86
62 Galectin-1 controls cardiac inflammation and ventricular remodeling during acute myocardial infarction. Am J Pathol 2012 0.86
63 Interstrain differences in chronic hepatitis and tumor development in a murine model of inflammation-mediated hepatocarcinogenesis. Hepatology 2013 0.86
64 Galectin-3 negatively regulates the frequency and function of CD4(+) CD25(+) Foxp3(+) regulatory T cells and influences the course of Leishmania major infection. Eur J Immunol 2013 0.86
65 Regulated expression of galectin-1 during T-cell activation involves Lck and Fyn kinases and signaling through MEK1/ERK, p38 MAP kinase and p70S6 kinase. Mol Cell Biochem 2004 0.85
66 Up-regulated expression of MICA on activated T lymphocytes involves Lck and Fyn kinases and signaling through MEK1/ERK, p38 MAP kinase, and calcineurin. J Leukoc Biol 2003 0.85
67 Galectin-1 serum levels reflect tumor burden and adverse clinical features in classical Hodgkin lymphoma. Blood 2013 0.85
68 Critical role of the solvent environment in galectin-1 binding to the disaccharide lactose. Biochemistry 2009 0.84
69 Galectin-1 induces 12/15-lipoxygenase expression in murine macrophages and favors their conversion toward a pro-resolving phenotype. Prostaglandins Other Lipid Mediat 2013 0.84
70 Impact of protein-glycan interactions in the regulation of autoimmunity and chronic inflammation. Autoimmun Rev 2006 0.83
71 Galectin-1 triggers epithelial-mesenchymal transition in human hepatocellular carcinoma cells. J Cell Physiol 2015 0.83
72 Cell-type specific regulation of galectin-3 expression by glucocorticoids in lung Clara cells and macrophages. Histol Histopathol 2011 0.82
73 Overexpression of inducible nitric oxide synthase and cyclooxygenase-2 in rat zinc-deficient lung: Involvement of a NF-kappaB dependent pathway. Nitric Oxide 2005 0.82
74 An integrated computational analysis of the structure, dynamics, and ligand binding interactions of the human galectin network. J Chem Inf Model 2011 0.82
75 Fine-tuning antitumor responses through the control of galectin-glycan interactions: an overview. Methods Mol Biol 2011 0.82
76 MLL-rearranged B lymphoblastic leukemias selectively express the immunoregulatory carbohydrate-binding protein galectin-1. Clin Cancer Res 2010 0.82
77 Binding of galectin-1 to αIIbβ₃ integrin triggers "outside-in" signals, stimulates platelet activation, and controls primary hemostasis. FASEB J 2012 0.82
78 Galectins in hematological malignancies. Curr Opin Hematol 2013 0.81
79 Neuroendocrine-immune disequilibrium and endometriosis: an interdisciplinary approach. Semin Immunopathol 2007 0.81
80 Lack of TNFR p55 results in heightened expression of IFN-γ and IL-17 during the development of reactive arthritis. J Immunol 2010 0.80
81 'Sweetening' pregnancy: galectins at the fetomaternal interface. Am J Reprod Immunol 2013 0.80
82 Galectin-1 confers immune privilege to human trophoblast: implications in recurrent fetal loss. Glycobiology 2012 0.79
83 Circulating anti-galectin-1 antibodies are associated with the severity of ocular disease in autoimmune and infectious uveitis. Invest Ophthalmol Vis Sci 2006 0.79
84 Dissecting the signal transduction pathways triggered by galectin-glycan interactions in physiological and pathological settings. IUBMB Life 2010 0.79
85 Targeting galectin-1-induced angiogenesis mitigates the severity of endometriosis. J Pathol 2014 0.78
86 Integrating structure and function of 'tandem-repeat' galectins. Front Biosci (Schol Ed) 2012 0.78
87 Study of galectins in tumor immunity: strategies and methods. Methods Mol Biol 2015 0.77
88 [Tolerance and autoimmunity. Novel therapeutic approaches]. Medicina (B Aires) 2009 0.77
89 Low-dose cyclophosphamide modulates galectin-1 expression and function in an experimental rat lymphoma model. Cancer Immunol Immunother 2006 0.77
90 [How do protein-glycan interactions regulate T-cell physiology?]. Medicina (B Aires) 2006 0.77
91 TNFRp55 controls regulatory T cell responses in Yersinia-induced reactive arthritis. Immunol Cell Biol 2012 0.77
92 The aggressiveness of murine lymphomas selected in vivo by growth rate correlates with galectin-1 expression and response to cyclophosphamide. Cancer Immunol Immunother 2011 0.77
93 Thwarting galectin-induced immunosuppression in breast cancer. Oncoimmunology 2013 0.77
94 Delineating the "galectin signature" of the tumor microenvironment. Oncoimmunology 2013 0.77
95 "Time sweet time": circadian characterization of galectin-1 null mice. J Circadian Rhythms 2010 0.77
96 A sweet path toward tolerance in the gut. Nat Med 2010 0.76
97 Galectins: new agonists of platelet activation. Biol Chem 2013 0.76
98 Identification of RANTES as a novel immunomodulator of the maternal allogeneic response. Clin Immunol 2004 0.75
99 Structural basis of redox-dependent modulation of galectin-1 dynamics and function. Glycobiology 2014 0.75
100 Linking the structure and thermal stability of beta-galactoside-binding protein galectin-1 to ligand binding and dimerization equilibria. Biochemistry 2010 0.75
101 TSLP1: a new piece in the puzzle of tumor-associated Th2-type inflammation. Immunotherapy 2011 0.75
102 Galectin-1 markedly reduces the incidence of resorptions in mice missing immunophilin FKBP52. Endocrinology 2012 0.75
103 [Nobel Prizes 2011: dendritic cells, toll-like receptors and their contribution to fundamental and translational medicine]. Rev Fac Cien Med Univ Nac Cordoba 2011 0.75
104 [Nobel Prize in Medicine in immunology: dendritic cells and the renaissance of innate immunity]. Medicina (B Aires) 2011 0.75
105 Galectin-8 promotes regulatory T-cell differentiation by modulating IL-2 and TGFβ signaling. Immunol Cell Biol 2016 0.75
106 State of the union: glycobiology and immunology in the Canadian Rockies. Glycobiology 2011 0.75
107 Predictive value of galectin-1 in the development and progression of HIV-associated lymphoma. AIDS 2017 0.75
108 Regulation of galectins by hypoxia and their relevance in angiogenesis: strategies and methods. Methods Mol Biol 2015 0.75
109 [Axonal regeneration in spinal cord injury: key role of galectin-1]. Medicina (B Aires) 2014 0.75
110 TNFRp55 modulates IL-6 and nitric oxide responses following Yersinia lipopolysaccharide stimulation in peritoneal macrophages. Immunobiology 2011 0.75
111 Galectins in the regulation of platelet biology. Methods Mol Biol 2015 0.75