1
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Initial sequencing and comparative analysis of the mouse genome.
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Nature
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2002
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96.15
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2
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Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project.
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Nature
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2007
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75.09
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3
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Genome-wide maps of chromatin state in pluripotent and lineage-committed cells.
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Nature
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2007
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65.18
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4
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Genome-scale DNA methylation maps of pluripotent and differentiated cells.
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Nature
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2008
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30.29
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5
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Solution hybrid selection with ultra-long oligonucleotides for massively parallel targeted sequencing.
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Nat Biotechnol
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2009
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27.17
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6
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Genome sequence, comparative analysis and haplotype structure of the domestic dog.
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Nature
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2005
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23.04
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7
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High-quality draft assemblies of mammalian genomes from massively parallel sequence data.
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Proc Natl Acad Sci U S A
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2010
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22.97
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8
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ARACHNE: a whole-genome shotgun assembler.
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Genome Res
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2002
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22.72
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9
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ALLPATHS: de novo assembly of whole-genome shotgun microreads.
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Genome Res
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2008
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20.61
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10
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Evolution of genes and genomes on the Drosophila phylogeny.
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Nature
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2007
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18.01
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11
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High-resolution mapping of copy-number alterations with massively parallel sequencing.
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Nat Methods
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2008
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12.56
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12
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Quality scores and SNP detection in sequencing-by-synthesis systems.
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Genome Res
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2008
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10.49
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13
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Analyzing and minimizing PCR amplification bias in Illumina sequencing libraries.
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Genome Biol
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2011
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9.18
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14
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A high-resolution map of human evolutionary constraint using 29 mammals.
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Nature
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2011
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8.67
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15
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Integrative analysis of the melanoma transcriptome.
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Genome Res
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2010
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8.46
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16
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Assemblathon 1: a competitive assessment of de novo short read assembly methods.
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Genome Res
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2011
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8.38
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17
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Analyses of deep mammalian sequence alignments and constraint predictions for 1% of the human genome.
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Genome Res
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2007
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7.05
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18
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ALLPATHS 2: small genomes assembled accurately and with high continuity from short paired reads.
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Genome Biol
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2009
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6.76
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19
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Insights from the genome of the biotrophic fungal plant pathogen Ustilago maydis.
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Nature
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2006
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5.52
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20
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The genomic basis of adaptive evolution in threespine sticklebacks.
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Nature
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2012
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5.20
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21
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A genome-wide map of diversity in Plasmodium falciparum.
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Nat Genet
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2006
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4.50
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22
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Characterizing and measuring bias in sequence data.
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Genome Biol
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2013
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4.39
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23
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An initial strategy for the systematic identification of functional elements in the human genome by low-redundancy comparative sequencing.
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Proc Natl Acad Sci U S A
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2005
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4.38
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24
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Assemblathon 2: evaluating de novo methods of genome assembly in three vertebrate species.
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Gigascience
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2013
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4.11
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25
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Molecular diagnosis of infantile mitochondrial disease with targeted next-generation sequencing.
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Sci Transl Med
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2012
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4.02
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26
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Finished bacterial genomes from shotgun sequence data.
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Genome Res
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2012
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3.86
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27
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A scalable, fully automated process for construction of sequence-ready barcoded libraries for 454.
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Genome Biol
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2010
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2.79
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28
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The African coelacanth genome provides insights into tetrapod evolution.
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Nature
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2013
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2.78
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29
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Assembly of polymorphic genomes: algorithms and application to Ciona savignyi.
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Genome Res
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2005
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2.69
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30
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Sensitive, specific polymorphism discovery in bacteria using massively parallel sequencing.
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Nat Methods
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2008
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2.61
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31
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DNA sequence and analysis of human chromosome 8.
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Nature
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2006
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1.91
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32
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DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.
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Nature
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2006
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1.81
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33
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Mutations causing medullary cystic kidney disease type 1 lie in a large VNTR in MUC1 missed by massively parallel sequencing.
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Nat Genet
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2013
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1.52
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34
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Paired-end sequencing of Fosmid libraries by Illumina.
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Genome Res
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2012
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1.52
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35
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Analysis of the DNA sequence and duplication history of human chromosome 15.
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Nature
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2006
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1.50
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36
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Facilitating genome navigation: survey sequencing and dense radiation-hybrid gene mapping.
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Nat Rev Genet
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2005
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1.33
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37
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Assisted assembly: how to improve a de novo genome assembly by using related species.
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Genome Biol
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2009
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1.28
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38
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Oxidative modification of M-type K(+) channels as a mechanism of cytoprotective neuronal silencing.
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EMBO J
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2006
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1.28
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39
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Distinct classes of pyramidal cells exhibit mutually exclusive firing patterns in hippocampal area CA3b.
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Hippocampus
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2008
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1.24
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40
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Angiotensin II regulates neuronal excitability via phosphatidylinositol 4,5-bisphosphate-dependent modulation of Kv7 (M-type) K+ channels.
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J Physiol
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2006
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1.16
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41
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Inositol triphosphate-mediated Ca2+ signals direct purinergic P2Y receptor regulation of neuronal ion channels.
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J Neurosci
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2007
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1.14
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42
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Human chromosome 11 DNA sequence and analysis including novel gene identification.
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Nature
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2006
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1.09
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43
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DNA sequence and analysis of human chromosome 18.
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Nature
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2005
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1.05
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44
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Local GABAergic signaling within sensory ganglia controls peripheral nociceptive transmission.
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J Clin Invest
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2017
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0.75
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