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1
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Genome-wide maps of chromatin state in pluripotent and lineage-committed cells.
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Nature
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2007
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65.18
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2
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Solution hybrid selection with ultra-long oligonucleotides for massively parallel targeted sequencing.
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Nat Biotechnol
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2009
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27.17
|
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3
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High-resolution mapping of copy-number alterations with massively parallel sequencing.
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Nat Methods
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2008
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12.56
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4
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Quality scores and SNP detection in sequencing-by-synthesis systems.
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Genome Res
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2008
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10.49
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5
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Analyzing and minimizing PCR amplification bias in Illumina sequencing libraries.
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Genome Biol
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2011
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9.18
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6
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A catalog of reference genomes from the human microbiome.
|
Science
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2010
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8.10
|
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7
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Mammalian microRNAs: experimental evaluation of novel and previously annotated genes.
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Genes Dev
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2010
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7.14
|
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8
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Comparative functional genomics of the fission yeasts.
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Science
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2011
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6.00
|
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9
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Medulloblastoma exome sequencing uncovers subtype-specific somatic mutations.
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Nature
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2012
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5.23
|
|
10
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Characterizing and measuring bias in sequence data.
|
Genome Biol
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2013
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4.39
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11
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ANG mutations segregate with familial and 'sporadic' amyotrophic lateral sclerosis.
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Nat Genet
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2006
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3.88
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12
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Finished bacterial genomes from shotgun sequence data.
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Genome Res
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2012
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3.86
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13
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Mutations in TMEM216 perturb ciliogenesis and cause Joubert, Meckel and related syndromes.
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Nat Genet
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2010
|
3.66
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14
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Genomic epidemiology of the Escherichia coli O104:H4 outbreaks in Europe, 2011.
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Proc Natl Acad Sci U S A
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2012
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3.42
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15
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De novo somatic mutations in components of the PI3K-AKT3-mTOR pathway cause hemimegalencephaly.
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Nat Genet
|
2012
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3.41
|
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16
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Quantitative deep sequencing reveals dynamic HIV-1 escape and large population shifts during CCR5 antagonist therapy in vivo.
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PLoS One
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2009
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3.40
|
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17
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Pacific biosciences sequencing technology for genotyping and variation discovery in human data.
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BMC Genomics
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2012
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2.92
|
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18
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A scalable, fully automated process for construction of sequence-ready barcoded libraries for 454.
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Genome Biol
|
2010
|
2.79
|
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19
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Evolutionarily assembled cis-regulatory module at a human ciliopathy locus.
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Science
|
2012
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1.74
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20
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Hybrid selection for sequencing pathogen genomes from clinical samples.
|
Genome Biol
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2011
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1.61
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21
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Genomics of Loa loa, a Wolbachia-free filarial parasite of humans.
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Nat Genet
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2013
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1.52
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22
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Premetazoan genome evolution and the regulation of cell differentiation in the choanoflagellate Salpingoeca rosetta.
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Genome Biol
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2013
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1.41
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23
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The Capsaspora genome reveals a complex unicellular prehistory of animals.
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Nat Commun
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2013
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1.39
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24
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Key considerations for measuring allelic expression on a genomic scale using high-throughput sequencing.
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Mol Ecol
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2010
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1.30
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25
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A cellular memory of developmental history generates phenotypic diversity in C. elegans.
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Curr Biol
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2010
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1.27
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26
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Regulated aggregative multicellularity in a close unicellular relative of metazoa.
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Elife
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2013
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1.18
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27
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Genome-wide identification and characterization of replication origins by deep sequencing.
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Genome Biol
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2012
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1.18
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28
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Distinctive expansion of potential virulence genes in the genome of the oomycete fish pathogen Saprolegnia parasitica.
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PLoS Genet
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2013
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1.18
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29
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Functional effects of a tandem duplication polymorphism in the 5'flanking region of the DRD4 gene.
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Biol Psychiatry
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2004
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1.10
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30
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Yeast sterol regulatory element-binding protein (SREBP) cleavage requires Cdc48 and Dsc5, a ubiquitin regulatory X domain-containing subunit of the Golgi Dsc E3 ligase.
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J Biol Chem
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2011
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1.07
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31
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Evaluation of the Golgi trafficking protein VPS54 (wobbler) as a candidate for ALS.
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Amyotroph Lateral Scler
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2008
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0.90
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32
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Increase in the relative expression of tau with four microtubule binding repeat regions in frontotemporal lobar degeneration and progressive supranuclear palsy brains.
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Acta Neuropathol
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2007
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0.88
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33
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Association analysis of the glycogen synthase kinase-3beta gene in bipolar disorder.
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Neurosci Lett
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2005
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0.82
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34
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Genes related to vascular disease (APOE, VLDL-R, DCP-1) and other vascular factors in late-life depression.
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Am J Geriatr Psychiatry
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2004
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0.82
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35
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No association of DYNC1H1 with sporadic ALS in a case-control study of a northern European derived population: a tagging SNP approach.
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Amyotroph Lateral Scler
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2006
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0.81
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36
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50bp deletion in the promoter for superoxide dismutase 1 (SOD1) reduces SOD1 expression in vitro and may correlate with increased age of onset of sporadic amyotrophic lateral sclerosis.
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Amyotroph Lateral Scler
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2008
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0.81
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37
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Semiconductor-based DNA sequencing of histone modification states.
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Nat Commun
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2013
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0.78
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38
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A familial form of pallidoluysionigral degeneration and amyotrophic lateral sclerosis with divergent clinical presentations.
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J Neuropathol Exp Neurol
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2007
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0.77
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39
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Variants in candidate ALS modifier genes linked to Cu/Zn superoxide dismutase do not explain divergent survival phenotypes.
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Neurosci Lett
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2005
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0.75
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40
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DNA sequence analysis of the conserved region around the SOD1 gene locus in recessively inherited ALS.
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Neurosci Lett
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2009
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0.75
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41
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Genetics, molecular biology, neuropathology and phenotype of frontal lobe dementia: a case history.
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Br J Psychiatry
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2002
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0.75
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