Published in Blood on February 04, 2010
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Early dynamic fate changes in haemogenic endothelium characterized at the single-cell level. Nat Commun (2013) 1.35
Hematopoietic stem cell emergence in the conceptus and the role of Runx1. Int J Dev Biol (2010) 1.11
Critical role of P1-Runx1 in mouse basophil development. Blood (2012) 1.07
A short history of hemogenic endothelium. Blood Cells Mol Dis (2013) 1.05
USF1 and hSET1A mediated epigenetic modifications regulate lineage differentiation and HoxB4 transcription. PLoS Genet (2013) 1.03
Differential regulation of the mouse and human Wnt5a alternative promoters A and B. DNA Cell Biol (2012) 0.90
Endothelial Smad4 restrains the transition to hematopoietic progenitors via suppression of ERK activation. Blood (2014) 0.83
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A view of human haematopoietic development from the Petri dish. Nat Rev Mol Cell Biol (2016) 0.80
Lack of Phenotypical and Morphological Evidences of Endothelial to Hematopoietic Transition in the Murine Embryonic Head during Hematopoietic Stem Cell Emergence. PLoS One (2016) 0.79
The RUNX1 +24 enhancer and P1 promoter identify a unique subpopulation of hematopoietic progenitor cells derived from human pluripotent stem cells. Stem Cells (2015) 0.79
Central Role of Core Binding Factor β2 in Mucosa-Associated Lymphoid Tissue Organogenesis in Mouse. PLoS One (2015) 0.78
Systems Pharmacogenomics Finds RUNX1 Is an Aspirin-Responsive Transcription Factor Linked to Cardiovascular Disease and Colon Cancer. EBioMedicine (2016) 0.78
An experimentally validated network of nine haematopoietic transcription factors reveals mechanisms of cell state stability. Elife (2016) 0.77
Runx family genes in a cartilaginous fish, the elephant shark (Callorhinchus milii). PLoS One (2014) 0.76
Precocious Phenotypic Transcription-Factor Expression during Early Development. J Cell Biochem (2016) 0.75
Generation of transgenic mouse fluorescent reporter lines for studying hematopoietic development. Methods Mol Biol (2014) 0.75
Combinatorial transcriptional control in blood stem/progenitor cells: genome-wide analysis of ten major transcriptional regulators. Cell Stem Cell (2010) 5.05
Runx1 expression marks long-term repopulating hematopoietic stem cells in the midgestation mouse embryo. Immunity (2002) 4.15
Flexible use of nuclear import pathways by HIV-1. Cell Host Microbe (2010) 3.08
The role of the Runx transcription factors in thymocyte differentiation and in homeostasis of naive T cells. J Exp Med (2007) 2.84
Genetic evidence supporting selection of the Valpha14i NKT cell lineage from double-positive thymocyte precursors. Immunity (2005) 2.72
RUNX proteins in transcription factor networks that regulate T-cell lineage choice. Nat Rev Immunol (2009) 2.49
Repression of the transcription factor Th-POK by Runx complexes in cytotoxic T cell development. Science (2008) 2.43
Reciprocal regulation of CD4/CD8 expression by SWI/SNF-like BAF complexes. Nature (2002) 2.41
Characterization of transcriptional networks in blood stem and progenitor cells using high-throughput single-cell gene expression analysis. Nat Cell Biol (2013) 2.40
Repression of interleukin-4 in T helper type 1 cells by Runx/Cbf beta binding to the Il4 silencer. J Exp Med (2007) 2.39
A role for Runx transcription factor signaling in dorsal root ganglion sensory neuron diversification. Neuron (2006) 2.26
Transcriptional reprogramming of mature CD4⁺ helper T cells generates distinct MHC class II-restricted cytotoxic T lymphocytes. Nat Immunol (2013) 2.11
Indispensable role of the Runx1-Cbfbeta transcription complex for in vivo-suppressive function of FoxP3+ regulatory T cells. Immunity (2009) 2.05
Lymphomyeloid contribution of an immune-restricted progenitor emerging prior to definitive hematopoietic stem cells. Cell Stem Cell (2013) 1.96
Cascading suppression of transcriptional silencers by ThPOK seals helper T cell fate. Nat Immunol (2008) 1.89
Mutual expression of the transcription factors Runx3 and ThPOK regulates intestinal CD4⁺ T cell immunity. Nat Immunol (2013) 1.86
Runx1-mediated hematopoietic stem-cell emergence is controlled by a Gata/Ets/SCL-regulated enhancer. Blood (2007) 1.82
Construction of an open-access database that integrates cross-reference information from the transcriptome and proteome of immune cells. Bioinformatics (2007) 1.73
Direct recruitment of polycomb repressive complex 1 to chromatin by core binding transcription factors. Mol Cell (2012) 1.71
Runx3 regulates integrin alpha E/CD103 and CD4 expression during development of CD4-/CD8+ T cells. J Immunol (2005) 1.57
Notch2 integrates signaling by the transcription factors RBP-J and CREB1 to promote T cell cytotoxicity. Nat Immunol (2008) 1.57
From hemangioblast to hematopoietic stem cell: an endothelial connection? Exp Hematol (2005) 1.53
Stromal cell lines from mouse aorta-gonads-mesonephros subregions are potent supporters of hematopoietic stem cell activity. Blood (2002) 1.48
Runx1 prevents wasting, myofibrillar disorganization, and autophagy of skeletal muscle. Genes Dev (2005) 1.46
Runx proteins regulate Foxp3 expression. J Exp Med (2009) 1.45
HOXB4's road map to stem cell expansion. Proc Natl Acad Sci U S A (2007) 1.43
Physical activity and risk of myocardial infarction after the fourth decade of life. Rev Port Cardiol (2005) 1.40
The SCL transcriptional network and BMP signaling pathway interact to regulate RUNX1 activity. Proc Natl Acad Sci U S A (2007) 1.36
The zinc-finger protein MAZR is part of the transcription factor network that controls the CD4 versus CD8 lineage fate of double-positive thymocytes. Nat Immunol (2010) 1.28
Transcriptional control of T-cell development. Int Immunol (2011) 1.24
Stem cell exhaustion due to Runx1 deficiency is prevented by Evi5 activation in leukemogenesis. Blood (2009) 1.23
RUNX1 is a key target in t(4;11) leukemias that contributes to gene activation through an AF4-MLL complex interaction. Cell Rep (2013) 1.22
Runx genes are direct targets of Scl/Tal1 in the yolk sac and fetal liver. Blood (2008) 1.21
Runx1 is expressed in adult mouse hematopoietic stem cells and differentiating myeloid and lymphoid cells, but not in maturing erythroid cells. Stem Cells (2004) 1.21
European birth cohorts for environmental health research. Environ Health Perspect (2011) 1.16
Developmental stages of myeloid dendritic cells in mouse bone marrow. Int Immunol (2003) 1.12
Co-receptor choice by V alpha14i NKT cells is driven by Th-POK expression rather than avoidance of CD8-mediated negative selection. J Exp Med (2010) 1.11
Runx1 protects hematopoietic stem/progenitor cells from oncogenic insult. Stem Cells (2007) 1.09
Critical role of P1-Runx1 in mouse basophil development. Blood (2012) 1.07
The transcription factor Th-POK negatively regulates Th17 differentiation in Vα14i NKT cells. Blood (2012) 1.07
A short history of hemogenic endothelium. Blood Cells Mol Dis (2013) 1.05
Runx1/Cbfβ2 complexes are required for lymphoid tissue inducer cell differentiation at two developmental stages. J Immunol (2010) 1.03
Fat mass ratio: an objective tool to define lipodystrophy in hiv-infected patients under antiretroviral therapy. J Clin Densitom (2010) 1.02
Association between dietary patterns and metabolic syndrome in a sample of Portuguese adults. Nutr J (2012) 1.02
Cd8 enhancer E8I and Runx factors regulate CD8α expression in activated CD8+ T cells. Proc Natl Acad Sci U S A (2011) 1.01
Decreased pathology and prolonged survival of human DC-SIGN transgenic mice during mycobacterial infection. J Immunol (2008) 1.01
Molecular cloning, mRNA expression and chromosomal localization of mouse angiotensin-converting enzyme-related carboxypeptidase (mACE2). DNA Seq (2002) 1.01
TNF-alpha regulates the effects of irradiation in the mouse bone marrow microenvironment. PLoS One (2010) 0.99
Transcriptional networks regulating hematopoietic cell fate decisions. Curr Opin Hematol (2007) 0.98
[Reliability and validity in measuring physical and mental health construct of the Portuguese version of MOS SF-36]. Acta Med Port (2007) 0.98
The mouse Runx1 +23 hematopoietic stem cell enhancer confers hematopoietic specificity to both Runx1 promoters. Blood (2009) 0.98
Alternative Runx1 promoter usage in mouse developmental hematopoiesis. Blood Cells Mol Dis (2009) 0.97
Absence of Runx3 expression in normal gastrointestinal epithelium calls into question its tumour suppressor function. EMBO Mol Med (2011) 0.95
Phylogenesis and regulated expression of the RUNT domain transcription factors RUNX1 and RUNX3. Blood Cells Mol Dis (2003) 0.93
Runx1-Cbfβ facilitates early B lymphocyte development by regulating expression of Ebf1. J Exp Med (2012) 0.92
ThPOK derepression is required for robust CD8 T cell responses to viral infection. J Immunol (2009) 0.92
Runx3 deficiency results in myeloproliferative disorder in aged mice. Blood (2013) 0.90
Major habitual dietary patterns are associated with acute myocardial infarction and cardiovascular risk markers in a southern European population. J Am Diet Assoc (2011) 0.90
Impact of Lipodystrophy on the prevalence and components of metabolic syndrome in HIV-infected patients. BMC Infect Dis (2011) 0.90
Interobserver agreement and consensus over the esthetic evaluation of conservative treatment for breast cancer. Breast (2005) 0.90
Smoking, alcohol, and dietary choices: evidence from the Portuguese National Health Survey. BMC Public Health (2007) 0.89
Overall and central obesity incidence in an urban Portuguese population. Prev Med (2009) 0.87
Antagonistic interplay between ThPOK and Runx in lineage choice of thymocytes. Blood Cells Mol Dis (2009) 0.87
Testing an adaptation of the EPIC physical activity questionnaire in Portuguese adults: a validation study that assesses the seasonal bias of self-report. Ann Hum Biol (2010) 0.87
APAP impact on metabolic syndrome in obstructive sleep apnea patients. Sleep Breath (2010) 0.87
Epigenetic Thpok silencing limits the time window to choose CD4(+) helper-lineage fate in the thymus. EMBO J (2013) 0.86
Adipokines, hormones related to body composition, and insulin resistance in HIV fat redistribution syndrome. BMC Infect Dis (2014) 0.84
Shared and distinct roles mediated through C-terminal subdomains of acute myeloid leukemia/Runt-related transcription factor molecules in murine development. Blood (2005) 0.84
5-years APAP adherence in OSA patients--do first impressions matter? Respir Med (2013) 0.83
Dlk1 is a negative regulator of emerging hematopoietic stem and progenitor cells. Haematologica (2012) 0.83
Controlling Hox gene expression and activity to build the vertebrate axial skeleton. Dev Dyn (2013) 0.83
Cbfb regulates bone development by stabilizing Runx family proteins. J Bone Miner Res (2015) 0.83
[Association between hyperuricemia and insulin resistance]. Acta Med Port (2011) 0.82
Visualizing blood cell emergence from aortic endothelium. Cell Stem Cell (2010) 0.82
Umbilical cord blood adipokines and newborn weight change. Arch Gynecol Obstet (2014) 0.82
Roles of repressive epigenetic machinery in lineage decision of T cells. Immunology (2013) 0.81
Chemical and biological evaluation of 153 Sm and 46/47 Sc complexes of indazolebisphosphonates for targeted radiotherapy. Appl Radiat Isot (2010) 0.81
The network of transcription factors that underlie the CD4 versus CD8 lineage decision. Int Immunol (2010) 0.80
Choosing observers for evaluation of aesthetic results in breast cancer conservative treatment. Int J Radiat Oncol Biol Phys (2005) 0.80
Interleukin-3Ralpha+ myeloid dendritic cells and mast cells develop simultaneously from different bone marrow precursors in cultures with interleukin-3. J Invest Dermatol (2003) 0.80
Diagnostic value of CD103 expression in bronchoalveolar lymphocytes in sarcoidosis. Respir Med (2012) 0.79
Normalization of renal aquaporin-2 water channel expression by fosinopril, valsartan, and combination therapy in congestive heart failure: a new mechanism of action. J Mol Cell Cardiol (2004) 0.78
Lipodystrophy defined by Fat Mass Ratio in HIV-infected patients is associated with a high prevalence of glucose disturbances and insulin resistance. BMC Infect Dis (2012) 0.78
Roles of VWRPY motif-mediated gene repression by Runx proteins during T-cell development. Immunol Cell Biol (2012) 0.78
The development and validation of the Portuguese risk score for detecting type 2 diabetes and impaired fasting glucose. Prim Care Diabetes (2013) 0.78
Core binding factor beta functions in the maintenance of stem cells and orchestrates continuous proliferation and differentiation in mouse incisors. Stem Cells (2011) 0.78
A restricted mixture model for dietary pattern analysis in small samples. Stat Med (2012) 0.78
Cutting edge: fine-tuning of Thpok gene activation by an enhancer in close proximity to its own silencer. J Immunol (2013) 0.77
Carotid intima media thickness is associated with body fat abnormalities in HIV-infected patients. BMC Infect Dis (2014) 0.77
Central/Peripheral fat mass ratio is associated with increased risk of hypertension in HIV-infected patients. J Clin Hypertens (Greenwich) (2012) 0.77
Phosphorylation of Runx1 at Ser249, Ser266, and Ser276 is dispensable for bone marrow hematopoiesis and thymocyte differentiation. Biochem Biophys Res Commun (2008) 0.77