Published in Br J Nutr on February 09, 2010
Seizure control by decanoic acid through direct AMPA receptor inhibition. Brain (2015) 1.56
Feeding healthy beagles medium-chain triglycerides, fish oil, and carnitine offsets age-related changes in serum fatty acids and carnitine metabolites. PLoS One (2012) 1.18
The nervous system and metabolic dysregulation: emerging evidence converges on ketogenic diet therapy. Front Neurosci (2012) 0.92
A ketogenic diet delays weight loss and does not impair working memory or motor function in the R6/2 1J mouse model of Huntington's disease. Physiol Behav (2011) 0.92
Prevention approaches in a preclinical canine model of Alzheimer's disease: benefits and challenges. Front Pharmacol (2014) 0.82
2015 ACVIM Small Animal Consensus Statement on Seizure Management in Dogs. J Vet Intern Med (2016) 0.82
Lauric acid-rich medium-chain triglycerides can substitute for other oils in cooking applications and may have limited pathogenicity. Open Heart (2016) 0.80
Effects of a ketogenic diet on hippocampal plasticity in freely moving juvenile rats. Physiol Rep (2015) 0.77
A randomised trial of a medium-chain TAG diet as treatment for dogs with idiopathic epilepsy. Br J Nutr (2015) 0.77
Cognition and Synaptic-Plasticity Related Changes in Aged Rats Supplemented with 8- and 10-Carbon Medium Chain Triglycerides. PLoS One (2016) 0.76
Beta-hydroxybutyrate Concentrations in Dogs with Acute Pancreatitis and Without Diabetes Mellitus. J Vet Intern Med (2016) 0.75
Cognitive dysfunction in cats: a syndrome we used to dismiss as 'old age'. J Feline Med Surg (2010) 1.44
Brain aging in the canine: a diet enriched in antioxidants reduces cognitive dysfunction. Neurobiol Aging (2002) 1.34
Size and reversal learning in the beagle dog as a measure of executive function and inhibitory control in aging. Learn Mem (2003) 1.32
Adalimumab safety in global clinical trials of patients with Crohn's disease. Inflamm Bowel Dis (2009) 1.30
Metabonomic investigations of aging and caloric restriction in a life-long dog study. J Proteome Res (2007) 1.21
Endothelial dysfunction in the streptozotocin-induced diabetic apoE-deficient mouse. Br J Pharmacol (2005) 1.19
Neurogenesis decreases with age in the canine hippocampus and correlates with cognitive function. Neurobiol Learn Mem (2007) 1.19
Locomotor activity rhythms in dogs vary with age and cognitive status. Behav Neurosci (2003) 1.19
PTSD symptom trajectories: from early to chronic response. Behav Res Ther (2006) 1.18
Region specific neuron loss in the aged canine hippocampus is reduced by enrichment. Neurobiol Aging (2006) 1.01
Frontal lobe volume, function, and beta-amyloid pathology in a canine model of aging. J Neurosci (2004) 1.01
Age-dependent decline in locomotor activity in dogs is environment specific. Physiol Behav (2002) 0.97
Further evidence for the cholinergic hypothesis of aging and dementia from the canine model of aging. Prog Neuropsychopharmacol Biol Psychiatry (2005) 0.96
Visuospatial impairments in aged canines (Canis familiaris): the role of cognitive-behavioral flexibility. Behav Neurosci (2002) 0.96
Mutations in the second zinc finger of human EKLF reduce promoter affinity but give rise to benign and disease phenotypes. Blood (2011) 0.95
Visuospatial function in the beagle dog: an early marker of cognitive decline in a model of human aging and dementia. Neurobiol Learn Mem (2006) 0.94
Application of an automated voxel-based morphometry technique to assess regional gray and white matter brain atrophy in a canine model of aging. Neuroimage (2005) 0.93
Accuracy of MRI for diagnosis of discogenic pain. Pain Physician (2008) 0.92
Stepped early psychological intervention for posttraumatic stress disorder, other anxiety disorders, and depression following serious injury. J Trauma Stress (2012) 0.92
Rosiglitazone enhances glucose tolerance by mechanisms other than reduction of fatty acid accumulation within skeletal muscle. Endocrinology (2004) 0.90
The canine model of human cognitive aging and dementia: pharmacological validity of the model for assessment of human cognitive-enhancing drugs. Prog Neuropsychopharmacol Biol Psychiatry (2005) 0.89
Cognitive dysfunction syndrome: a disease of canine and feline brain aging. Vet Clin North Am Small Anim Pract (2012) 0.89
Guidelines for peer support in high-risk organizations: an international consensus study using the Delphi method. J Trauma Stress (2012) 0.88
Synergistic effects of long-term antioxidant diet and behavioral enrichment on beta-amyloid load and non-amyloidogenic processing in aged canines. J Neurosci (2010) 0.87
Chronic antioxidant and mitochondrial cofactor administration improves discrimination learning in aged but not young dogs. Prog Neuropsychopharmacol Biol Psychiatry (2005) 0.86
Dietary trans-fat combined with monosodium glutamate induces dyslipidemia and impairs spatial memory. Physiol Behav (2009) 0.85
A comparison of egocentric and allocentric age-dependent spatial learning in the beagle dog. Prog Neuropsychopharmacol Biol Psychiatry (2005) 0.84
Immunization with fibrillar Abeta(1-42) in young and aged canines: Antibody generation and characteristics, and effects on CSF and brain Abeta. Vaccine (2006) 0.83
Neuroinflammation in Alzheimer's disease: are NSAIDs and selective COX-2 inhibitors the next line of therapy? J Alzheimers Dis (2010) 0.83
Evaluation of cognitive learning, memory, psychomotor, immunologic, and retinal functions in healthy puppies fed foods fortified with docosahexaenoic acid-rich fish oil from 8 to 52 weeks of age. J Am Vet Med Assoc (2012) 0.82
Noninvasive measurements of body composition and body water via quantitative magnetic resonance, deuterium water, and dual-energy x-ray absorptiometry in awake and sedated dogs. Am J Vet Res (2013) 0.82
Behavior problems in geriatric pets. Vet Clin North Am Small Anim Pract (2005) 0.82
Potential cognitive enhancing and disease modification effects of SSRIs for Alzheimer's disease. Neuropsychiatr Dis Treat (2007) 0.82
Short-term supplementation with acetyl-L-carnitine and lipoic acid alters plasma protein carbonyl levels but does not improve cognition in aged beagles. Exp Gerontol (2009) 0.81
Comparison of the cognitive palatability assessment protocol and the two-pan test for use in assessing palatability of two similar foods in dogs. Am J Vet Res (2004) 0.81
Effects of age on measures of complex working memory span in the beagle dog (Canis familiaris) using two versions of a spatial list learning paradigm. Learn Mem (2003) 0.81
Driving research in infant and children's nutrition: a perspective on industry. Am J Clin Nutr (2009) 0.81
Age and distraction are determinants of performance on a novel visual search task in aged Beagle dogs. Age (Dordr) (2011) 0.81
Concept abstraction in the aging dog: development of a protocol using successive discrimination and size concept tasks. Behav Brain Res (2004) 0.81
Introduction to the symposium: Appropriate animal models for nutritional research in health and disease. J Nutr (2008) 0.80
Noninvasive measurements of body composition and body water via quantitative magnetic resonance, deuterium water, and dual-energy x-ray absorptiometry in cats. Am J Vet Res (2013) 0.80
Effects of strength training on body composition and bone mineral content in children who are obese. J Strength Cond Res (2005) 0.80
Severe acute respiratory syndrome: correlation between clinical outcome and radiologic features. Radiology (2004) 0.80
Effect of trans-fat, fructose and monosodium glutamate feeding on feline weight gain, adiposity, insulin sensitivity, adipokine and lipid profile. Br J Nutr (2011) 0.79
Acquisition of a visual discrimination and reversal learning task by Labrador retrievers. Anim Cogn (2013) 0.79
Effects of scopolamine challenge on regional cerebral blood volume. A pharmacological model to validate the use of contrast enhanced magnetic resonance imaging to assess cerebral blood volume in a canine model of aging. Prog Neuropsychopharmacol Biol Psychiatry (2005) 0.79
Cognitive decline and human (Homo sapiens) aging: an investigation using a comparative neuropsychological approach. J Comp Psychol (2007) 0.79
Healing effect of a two-herb recipe (NF3) on foot ulcers in Chinese patients with diabetes: a randomized double-blind placebo-controlled study. J Diabetes (2014) 0.78
Aged dogs demonstrate both increased sensitivity to scopolamine impairment and decreased muscarinic receptor density. Pharmacol Biochem Behav (2011) 0.78
Spatial reversal learning is impaired by age in pet dogs. Age (Dordr) (2013) 0.77
Nutritional management of brain aging in dogs. J Am Vet Med Assoc (2005) 0.77
Prior experience, antioxidants, and mitochondrial cofactors improve cognitive function in aged beagles. Vet Ther (2004) 0.77
A preclinical cognitive test battery to parallel the National Institute of Health Toolbox in humans: bridging the translational gap. Neurobiol Aging (2013) 0.77
Clinical signs and management of anxiety, sleeplessness, and cognitive dysfunction in the senior pet. Vet Clin North Am Small Anim Pract (2011) 0.77
Amyloid-modifying therapies for Alzheimer's disease: therapeutic progress and its implications. Age (Dordr) (2010) 0.77
Extensive spatial training does not negate age differences in response latency. Brain Res (2006) 0.76
Improvement of short-term memory performance in aged beagles by a nutraceutical supplement containing phosphatidylserine, Ginkgo biloba, vitamin E, and pyridoxine. Can Vet J (2008) 0.76
Nutrigenomics of hepatic steatosis in a feline model: effect of monosodium glutamate, fructose, and Trans-fat feeding. Genes Nutr (2011) 0.76
An investigation of the relationship between response latency across several cognitive tasks in the beagle dog. Prog Neuropsychopharmacol Biol Psychiatry (2005) 0.76
Assessment of nutritional interventions for modification of age-associated cognitive decline using a canine model of human aging. Age (Dordr) (2005) 0.76
Cholinesterase inhibitors improve both memory and complex learning in aged beagle dogs. J Alzheimers Dis (2011) 0.76
Cognitive domains in the dog: independence of working memory from object learning, selective attention, and motor learning. Anim Cogn (2015) 0.76
Perturbations in laboratory values after coronary artery bypass graft surgery with cardiopulmonary bypass. J Cardiothorac Vasc Anesth (2005) 0.75
Understanding the Early Support Needs of Survivors of Traumatic Events: The Example of Severe Injury Survivors. Psychol Trauma (2017) 0.75
Pharmaceutical and other commercial uses of the dog model. Prog Neuropsychopharmacol Biol Psychiatry (2005) 0.75
Identifying patients at low risk for activity-related events: the RARE Score. J Cardiopulm Rehabil Prev (2014) 0.75
A novel method for assessing contrast sensitivity in the beagle dog is sensitive to age and an antioxidant enriched food. Prog Neuropsychopharmacol Biol Psychiatry (2005) 0.75
Response latency in Canis familiaris: mental ability or mental strategy? Behav Neurosci (2003) 0.75
Adrafinil disrupts performance on a delayed nonmatching-to-position task in aged beagle dogs. Pharmacol Biochem Behav (2003) 0.75
Effect of feeding patterns on performance of a visuospatial memory task in the beagle dog: a novel cognitive-based protocol for assessing satiety. Prog Neuropsychopharmacol Biol Psychiatry (2005) 0.75
Cognitive enhancement in middle-aged and old cats with dietary supplementation with a nutrient blend containing fish oil, B vitamins, antioxidants and arginine. Br J Nutr (2012) 0.75