Published in J Neurosci Res on July 01, 2010
The mitochondria-targeted antioxidant MitoQ prevents loss of spatial memory retention and early neuropathology in a transgenic mouse model of Alzheimer's disease. J Neurosci (2011) 1.26
Crosstalk between apoptosis and autophagy: molecular mechanisms and therapeutic strategies in cancer. J Cell Death (2013) 0.96
c-Jun N-terminal Kinase (JNK) Signaling as a Therapeutic Target for Alzheimer's Disease. Front Pharmacol (2016) 0.90
SUMO1 promotes Aβ production via the modulation of autophagy. Autophagy (2015) 0.89
Caspases: therapeutic targets in neurologic disease. Neurotherapeutics (2015) 0.83
Amyloid beta-mediated epigenetic alteration of insulin-like growth factor binding protein 3 controls cell survival in Alzheimer's disease. PLoS One (2014) 0.78
Transcriptomic analysis unveils correlations between regulative apoptotic caspases and genes of cholesterol homeostasis in human brain. PLoS One (2014) 0.76
Amyloid Beta-Mediated Hypomethylation of Heme Oxygenase 1 Correlates with Cognitive Impairment in Alzheimer's Disease. PLoS One (2016) 0.75
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
Depletion of GGA3 stabilizes BACE and enhances beta-secretase activity. Neuron (2007) 3.98
Self-regulated Plk1 recruitment to kinetochores by the Plk1-PBIP1 interaction is critical for proper chromosome segregation. Mol Cell (2006) 3.38
Morbidity and related factors among elderly people in South Korea: results from the Ansan Geriatric (AGE) cohort study. BMC Public Health (2007) 1.59
An adaptation of the Korean mini-mental state examination (K-MMSE) in elderly Koreans: demographic influence and population-based norms (the AGE study). Arch Gerontol Geriatr (2007) 1.50
Interaction between -786TC polymorphism in the endothelial nitric oxide synthase gene and smoking for myocardial infarction in Korean population. Clin Chim Acta (2005) 1.49
Validation of the Patient Health Questionnaire-9 Korean version in the elderly population: the Ansan Geriatric study. Compr Psychiatry (2007) 1.41
Endothelial nitric oxide synthase gene is associated with vessel stenosis in Korean population. Clin Chim Acta (2005) 1.39
High-density single-nucleotide polymorphism maps of the human genome. Genomics (2005) 1.27
Caspase activation increases beta-amyloid generation independently of caspase cleavage of the beta-amyloid precursor protein (APP). J Biol Chem (2003) 1.26
Oxidative stress caused by inactivation of glutathione peroxidase and adaptive responses. Biol Chem (2003) 1.15
hVAPB, the causative gene of a heterogeneous group of motor neuron diseases in humans, is functionally interchangeable with its Drosophila homologue DVAP-33A at the neuromuscular junction. Hum Mol Genet (2007) 1.15
Identification of ASK1, MKK4, JNK, c-Jun, and caspase-3 as a signaling cascade involved in cadmium-induced neuronal cell apoptosis. Biochem Biophys Res Commun (2005) 1.13
The cutoff values of visceral fat area and waist circumference for identifying subjects at risk for metabolic syndrome in elderly Korean: Ansan Geriatric (AGE) cohort study. BMC Public Health (2009) 1.12
No difference in stroke knowledge between Korean adherents to traditional and western medicine - the AGE study: an epidemiological study. BMC Public Health (2006) 1.10
Beta-amyloid (1-42)-induced learning and memory deficits in mice: involvement of oxidative burdens in the hippocampus and cerebral cortex. Behav Brain Res (2004) 1.07
Nox 2 stimulates muscle differentiation via NF-kappaB/iNOS pathway. Free Radic Biol Med (2005) 1.07
Dexamethasone coordinately regulates angiopoietin-1 and VEGF: a mechanism of glucocorticoid-induced stabilization of blood-brain barrier. Biochem Biophys Res Commun (2008) 1.03
Comparison of the humoral and cellular immune responses between body and head lice following bacterial challenge. Insect Biochem Mol Biol (2011) 1.01
Leukemia inhibitory factor blocks early differentiation of skeletal muscle cells by activating ERK. Biochim Biophys Acta (2004) 0.98
Induction of thioredoxin reductase as an adaptive response to acrolein in human umbilical vein endothelial cells. Biochem Biophys Res Commun (2005) 0.96
Identification of peripheral inflammatory markers between normal control and Alzheimer's disease. BMC Neurol (2011) 0.95
Mutations of acetylcholinesterase1 contribute to prothiofos-resistance in Plutella xylostella (L.). Biochem Biophys Res Commun (2006) 0.94
Adiposity parameters and cognitive function in the elderly: application of "Jolly Fat" hypothesis to cognition. Arch Gerontol Geriatr (2008) 0.94
Identification of the binding site of methylglyoxal on glutathione peroxidase: methylglyoxal inhibits glutathione peroxidase activity via binding to glutathione binding sites Arg 184 and 185. Free Radic Res (2003) 0.93
Impaired mitochondrial dynamics and Nrf2 signaling contribute to compromised responses to oxidative stress in striatal cells expressing full-length mutant huntingtin. PLoS One (2013) 0.92
RNA interference of pheromone biosynthesis-activating neuropeptide receptor suppresses mating behavior by inhibiting sex pheromone production in Plutella xylostella (L.). Insect Biochem Mol Biol (2011) 0.91
Presenilin 1/gamma-secretase is associated with cadmium-induced E-cadherin cleavage and COX-2 gene expression in T47D breast cancer cells. Toxicol Sci (2008) 0.91
Troglitazone acutely inhibits protein synthesis in endothelial cells via a novel mechanism involving protein phosphatase 2A-dependent p70 S6 kinase inhibition. Am J Physiol Cell Physiol (2006) 0.90
SIRT1 regulates tyrosine hydroxylase expression and differentiation of neuroblastoma cells via FOXO3a. FEBS Lett (2009) 0.90
SUMO1 promotes Aβ production via the modulation of autophagy. Autophagy (2015) 0.89
Obesity and depressive symptoms in elderly Koreans: evidence for the "Jolly Fat" hypothesis from the Ansan Geriatric (AGE) Study. Arch Gerontol Geriatr (2009) 0.89
Mechanisms of Amyloid-β Peptide Clearance: Potential Therapeutic Targets for Alzheimer's Disease. Biomol Ther (Seoul) (2012) 0.89
MEK1 plays contrary stage-specific roles in skeletal myogenic differentiation. Cell Signal (2009) 0.89
Lack of evidence for contribution of Glu298Asp (G894T) polymorphism of endothelial nitric oxide synthase gene to plasma nitric oxide levels. Thromb Res (2002) 0.88
Plasma homocysteine is associated with the risk of mild cognitive impairment in an elderly Korean population. J Nutr (2007) 0.88
Metabolic state determines sensitivity to cellular stress in Huntington disease: normalization by activation of PPARγ. PLoS One (2012) 0.87
Expression of HAT1 and HDAC1, 2, 3 in Diffuse Large B-Cell Lymphomas, Peripheral T-Cell Lymphomas, and NK/T-Cell Lymphomas. Korean J Pathol (2012) 0.87
SUMO1 modulates Aβ generation via BACE1 accumulation. Neurobiol Aging (2012) 0.87
Normal prion protein in Drosophila enhances the toxicity of pathogenic polyglutamine proteins and alters susceptibility to oxidative and autophagy signaling modulators. Biochem Biophys Res Commun (2010) 0.86
A Drosophila model of GSS syndrome suggests defects in active zones are responsible for pathogenesis of GSS syndrome. Hum Mol Genet (2010) 0.86
Swedish mutation within amyloid precursor protein modulates global gene expression towards the pathogenesis of Alzheimer's disease. BMB Rep (2010) 0.85
Molecular properties of a venom allergen-like protein suggest a parasitic function in the pinewood nematode Bursaphelenchus xylophilus. Int J Parasitol (2011) 0.85
Hypoxia-induced endothelial NO synthase gene transcriptional activation is mediated through the tax-responsive element in endothelial cells. Hypertension (2006) 0.85
Mitogen-activated protein kinase kinase 1 (MEK1) stabilizes MyoD through direct phosphorylation at tyrosine 156 during myogenic differentiation. J Biol Chem (2011) 0.85
Study design and methods of the Ansan Geriatric Study (AGE study). BMC Neurol (2009) 0.84
A survey of depressive symptoms among South Korean adults after the Korean financial crisis of late 1997: prevalence and correlates. Ann Epidemiol (2005) 0.84
Cadmium induces N-cadherin cleavage via ERK-mediated γ-secretase activation in C6 astroglia cells. Toxicol Lett (2013) 0.83
Cyclin-dependent kinase 5 phosphorylates endothelial nitric oxide synthase at serine 116. Hypertension (2010) 0.83
Smoking status-dependent association of the 27-bp repeat polymorphism in intron 4 of endothelial nitric oxide synthase gene with plasma nitric oxide concentrations. Clin Chim Acta (2002) 0.83
Choline acetyltransferase 2384G>a polymorphism and the risk of Alzheimer disease. Alzheimer Dis Assoc Disord (2012) 0.83
Three acetylcholinesterases of the pinewood nematode, Bursaphelenchus xylophilus: insights into distinct physiological functions. Mol Biochem Parasitol (2010) 0.83
In vivo bone formation by human marrow stromal cells in biodegradable scaffolds that release dexamethasone and ascorbate-2-phosphate. Biochem Biophys Res Commun (2005) 0.83
γ-Secretase-dependent cleavage of E-cadherin by staurosporine in breast cancer cells. Cell Commun Adhes (2012) 0.83
Exercise ameliorates cognition impairment due to restraint stress-induced oxidative insult and reduced BDNF level. Biochem Biophys Res Commun (2013) 0.82
Oncostatin M induces growth arrest of skeletal muscle cells in G1 phase by regulating cyclin D1 protein level. Cell Signal (2007) 0.81
A soluble acetylcholinesterase provides chemical defense against xenobiotics in the pinewood nematode. PLoS One (2011) 0.81
Characterization of 458 single nucleotide polymorphisms of disease candidate genes in the Korean population. J Hum Genet (2003) 0.81
Protection against kainate neurotoxicity by ginsenosides: attenuation of convulsive behavior, mitochondrial dysfunction, and oxidative stress. J Neurosci Res (2009) 0.81
Glutamate receptor-mediated regulation of c-fos expression in cultured microglia. Biochem Biophys Res Commun (2004) 0.80
Rapid increase in endothelial nitric oxide production by bradykinin is mediated by protein kinase A signaling pathway. Biochem Biophys Res Commun (2003) 0.80
Glutamate carboxypeptidase II: an amyloid peptide-degrading enzyme with physiological function in the brain. FASEB J (2010) 0.80
Body mass index cutoffs for underweight, overweight, and obesity in South Korean schoolgirls. Obes Res (2005) 0.80
Ubc9 gene polymorphisms and late-onset Alzheimer's disease in the Korean population: a genetic association study. Neurosci Lett (2009) 0.80
DNA methylation of the 5'-untranslated region at +298 and +351 represses BACE1 expression in mouse BV-2 microglial cells. Biochem Biophys Res Commun (2011) 0.80
Pharmacogenetic regulation of acetylcholinesterase activity in Drosophila reveals the regulatory mechanisms of AChE inhibitors in synaptic plasticity. Neurochem Res (2011) 0.79
Proteomic and biochemical analyses reveal the activation of unfolded protein response, ERK-1/2 and ribosomal protein S6 signaling in experimental autoimmune myocarditis rat model. BMC Genomics (2011) 0.79
A combination of biochemical and proteomic analyses reveals Bx-LEC-1 as an antigenic target for the monoclonal antibody 3-2A7-2H5-D9-F10 specific to the pine wood nematode. Mol Cell Proteomics (2010) 0.79
Construction and characterization of subtractive stage-specific expressed sequence tag (EST) libraries of the pinewood nematode Bursaphelenchus xylophilus. Genomics (2009) 0.79
Plasma carbonic anhydrase II protein is elevated in Alzheimer's disease. J Alzheimers Dis (2010) 0.78
Cell type-specific upregulation of myristoylated alanine-rich C kinase substrate and protein kinase C-alpha, -beta I, -beta II, and -delta in microglia following kainic acid-induced seizures. Exp Mol Med (2006) 0.78
Trichostatin A epigenetically increases calpastatin expression and inhibits calpain activity and calcium-induced SH-SY5Y neuronal cell toxicity. FEBS J (2013) 0.77
Dexamethasone increases angiopoietin-1 and quiescent hematopoietic stem cells: a novel mechanism of dexamethasone-induced hematoprotection. FEBS Lett (2008) 0.77
The Biochemical Adaptations of Spotted Wing Drosophila (Diptera: Drosophilidae) to Fresh Fruits Reduced Fructose Concentrations and Glutathione-S Transferase Activities. J Econ Entomol (2016) 0.77
Nicotinamide reduces dopamine in postnatal hypothalamus and causes dopamine-deficient phenotype. Neurosci Lett (2009) 0.77
Induction of thioredoxin reductase gene expression by peroxynitrite in human umbilical vein endothelial cells. Biol Chem (2002) 0.77
Elevated Epstein-Barr Virus Antibody Level is Associated with Cognitive Decline in the Korean Elderly. J Alzheimers Dis (2016) 0.77
A micro-scale surface-structured PCL scaffold fabricated by a 3D plotter and a chemical blowing agent. J Biomater Sci Polym Ed (2010) 0.76
Polycation-mediated enhancement of retroviral transduction efficiency depends on target cell types and pseudotyped Env proteins: implication for gene transfer into neural stem cells. Neurochem Int (2012) 0.76
Retinoic acid decreases nitric oxide production in endothelial cells: a role of phosphorylation of endothelial nitric oxide synthase at Ser(1179). Biochem Biophys Res Commun (2005) 0.76
Among γ-secretase substrates Notch1 alone is sufficient to block neurogenesis but does not confer self-renewal properties to neural stem cells. Biochem Biophys Res Commun (2010) 0.76
No association of prion protein gene polymorphisms with Alzheimer's disease in Korean population. Exp Mol Med (2006) 0.76
Cerebral white matter lesions and hypertension status in the elderly Korean: the Ansan Study. Arch Gerontol Geriatr (2004) 0.75