Published in BMJ on February 09, 2010
Hypothermia and other treatment options for neonatal encephalopathy: an executive summary of the Eunice Kennedy Shriver NICHD workshop. J Pediatr (2011) 2.22
Perinatal interventions and survival in resource-poor settings: which work, which don't, which have the jury out? Arch Dis Child (2010) 1.77
Treatment advances in neonatal neuroprotection and neurointensive care. Lancet Neurol (2011) 1.57
Comparison of Bayley-2 and Bayley-3 scores at 18 months in term infants following neonatal encephalopathy and therapeutic hypothermia. Dev Med Child Neurol (2013) 1.56
Feasibility of autologous cord blood cells for infants with hypoxic-ischemic encephalopathy. J Pediatr (2013) 1.41
Perinatal events and early magnetic resonance imaging in therapeutic hypothermia. J Pediatr (2010) 1.38
The biological basis of injury and neuroprotection in the fetal and neonatal brain. Int J Dev Neurosci (2011) 1.31
Glial fibrillary acidic protein as a biomarker for neonatal hypoxic-ischemic encephalopathy treated with whole-body cooling. Am J Obstet Gynecol (2011) 1.31
Erythropoietin for neuroprotection in neonatal encephalopathy: safety and pharmacokinetics. Pediatrics (2012) 1.29
Hypothermia for acute brain injury--mechanisms and practical aspects. Nat Rev Neurol (2012) 1.28
Perinatal hypoxic-ischemic encephalopathy. J Biomed Biotechnol (2010) 1.23
Risk factors for epilepsy in children with neonatal encephalopathy. Pediatr Res (2011) 1.14
Concurrent erythropoietin and hypothermia treatment improve outcomes in a term nonhuman primate model of perinatal asphyxia. Dev Neurosci (2013) 1.13
Intranasal mesenchymal stem cell treatment for neonatal brain damage: long-term cognitive and sensorimotor improvement. PLoS One (2013) 1.12
A new neurological focus in neonatal intensive care. Nat Rev Neurol (2011) 1.11
Which neuroprotective agents are ready for bench to bedside translation in the newborn infant? J Pediatr (2012) 1.07
Molecular mechanisms of neonatal brain injury. Neurol Res Int (2012) 1.07
A new broadband near-infrared spectroscopy system for in-vivo measurements of cerebral cytochrome-c-oxidase changes in neonatal brain injury. Biomed Opt Express (2014) 1.07
Potential biomarkers for hypoxic-ischemic encephalopathy. Semin Fetal Neonatal Med (2010) 1.06
Implementation and conduct of therapeutic hypothermia for perinatal asphyxial encephalopathy in the UK--analysis of national data. PLoS One (2012) 0.98
Fetal stress and programming of hypoxic/ischemic-sensitive phenotype in the neonatal brain: mechanisms and possible interventions. Prog Neurobiol (2012) 0.97
Bumetanide augments the neuroprotective efficacy of phenobarbital plus hypothermia in a neonatal hypoxia-ischemia model. Pediatr Res (2012) 0.97
The role of cytokines and inflammatory cells in perinatal brain injury. Neurol Res Int (2012) 0.96
Cerebral inflammation and mobilization of the peripheral immune system following global hypoxia-ischemia in preterm sheep. J Neuroinflammation (2013) 0.94
Predictive value of the amplitude integrated EEG in infants with hypoxic ischaemic encephalopathy: data from a randomised trial of therapeutic hypothermia. Arch Dis Child Fetal Neonatal Ed (2013) 0.94
Mechanisms of perinatal arterial ischemic stroke. J Cereb Blood Flow Metab (2014) 0.93
Brain barrier properties and cerebral blood flow in neonatal mice exposed to cerebral hypoxia-ischemia. J Cereb Blood Flow Metab (2015) 0.92
Blood-brain barrier dysfunction in disorders of the developing brain. Front Neurosci (2015) 0.92
Apgar scores at 10 min and outcomes at 6-7 years following hypoxic-ischaemic encephalopathy. Arch Dis Child Fetal Neonatal Ed (2013) 0.92
Stem cell therapy to protect and repair the developing brain: a review of mechanisms of action of cord blood and amnion epithelial derived cells. Front Neurosci (2013) 0.91
Ceftriaxone attenuates hypoxic-ischemic brain injury in neonatal rats. J Biomed Sci (2011) 0.91
Short-term outcomes of newborns with perinatal acidemia who are not eligible for systemic hypothermia therapy. J Pediatr (2012) 0.91
Hypothermia therapy for neonatal hypoxic ischemic encephalopathy in the state of California. J Pediatr (2014) 0.91
Early Anatomical Injury Patterns Predict Epilepsy in Head Cooled Neonates With Hypoxic-Ischemic Encephalopathy. Pediatr Neurol (2015) 0.90
Randomized trial of early developmental intervention on outcomes in children after birth asphyxia in developing countries. J Pediatr (2012) 0.90
Stem cell therapy for neonatal hypoxic-ischemic encephalopathy. Front Neurol (2014) 0.89
Antenatal allopurinol reduces hippocampal brain damage after acute birth asphyxia in late gestation fetal sheep. Reprod Sci (2013) 0.89
Therapeutic hypothermia for neonatal encephalopathy in low- and middle-income countries: a systematic review and meta-analysis. PLoS One (2013) 0.89
Modelling Blood Flow and Metabolism in the Preclinical Neonatal Brain during and Following Hypoxic-Ischaemia. PLoS One (2015) 0.88
Xenon and sevoflurane provide analgesia during labor and fetal brain protection in a perinatal rat model of hypoxia-ischemia. PLoS One (2012) 0.88
Effect of inborn vs. outborn delivery on neurodevelopmental outcomes in infants with hypoxic-ischemic encephalopathy: secondary analyses of the NICHD whole-body cooling trial. Pediatr Res (2012) 0.88
Esophageal mechanosensitive mechanisms are impaired in neonates with hypoxic-ischemic encephalopathy. J Pediatr (2012) 0.88
Lower incidence of seizure among neonates treated with therapeutic hypothermia. J Child Neurol (2013) 0.87
New horizons for newborn brain protection: enhancing endogenous neuroprotection. Arch Dis Child Fetal Neonatal Ed (2015) 0.87
Therapeutic Hypothermia for Neonatal Hypoxic-Ischemic Encephalopathy - Where to from Here? Front Neurol (2015) 0.86
Therapeutic hypothermia for neonatal encephalopathy results in improved microstructure and metabolism in the deep gray nuclei. AJNR Am J Neuroradiol (2012) 0.86
Systemic effects of whole-body cooling to 35 °C, 33.5 °C, and 30 °C in a piglet model of perinatal asphyxia: implications for therapeutic hypothermia. Pediatr Res (2012) 0.85
Sex differences in behavioral outcomes following temperature modulation during induced neonatal hypoxic ischemic injury in rats. Brain Sci (2015) 0.85
Pharmacokinetics and pharmacodynamics of medication in asphyxiated newborns during controlled hypothermia. The PharmaCool multicenter study. BMC Pediatr (2012) 0.84
Argon protects against hypoxic-ischemic brain injury in neonatal rats through activation of nuclear factor (erythroid-derived 2)-like 2. Oncotarget (2016) 0.83
Partial neural protection with prophylactic low-dose melatonin after asphyxia in preterm fetal sheep. J Cereb Blood Flow Metab (2013) 0.82
Creatine supplementation during pregnancy: summary of experimental studies suggesting a treatment to improve fetal and neonatal morbidity and reduce mortality in high-risk human pregnancy. BMC Pregnancy Childbirth (2014) 0.82
ADVANCES IN THE CELL-BASED TREATMENT OF NEONATAL HYPOXIC-ISCHEMIC BRAIN INJURY. Future Neurol (2013) 0.82
SDF-1α/CXCR4 Axis Mediates The Migration of Mesenchymal Stem Cells to The Hypoxic-Ischemic Brain Lesion in A Rat Model. Cell J (2015) 0.82
Mild hypothermia combined with neural stem cell transplantation for hypoxic-ischemic encephalopathy: neuroprotective effects of combined therapy. Neural Regen Res (2014) 0.81
Deleterious effects of high dose connexin 43 mimetic peptide infusion after cerebral ischaemia in near-term fetal sheep. Int J Mol Sci (2012) 0.81
Early antioxidant treatment and delayed hypothermia after hypoxia-ischemia have no additive neuroprotection in newborn pigs. Anesth Analg (2012) 0.81
Safety and efficacy of topiramate in neonates with hypoxic ischemic encephalopathy treated with hypothermia (NeoNATI). BMC Pediatr (2012) 0.81
Combined treatment of xenon and hypothermia in newborn rats--additive or synergistic effect? PLoS One (2014) 0.80
Cord blood mononuclear cells prevent neuronal apoptosis in response to perinatal asphyxia in the newborn lamb. J Physiol (2015) 0.80
Changes in serum cytokine and cortisol levels in normothermic and hypothermic term neonates after perinatal asphyxia. Inflamm Res (2012) 0.80
Pitfalls in the quest of neuroprotectants for the perinatal brain. Dev Neurosci (2011) 0.80
Mesenchymal stem/stromal cells-a key mediator for regeneration after perinatal morbidity? Mol Cell Pediatr (2016) 0.80
How long is too long for cerebral cooling after ischemia in fetal sheep? J Cereb Blood Flow Metab (2015) 0.80
Hypoxic Ischemic Encephalopathy: Pathophysiology and Experimental Treatments. Newborn Infant Nurs Rev (2011) 0.80
Docosahexaenoic acid augments hypothermic neuroprotection in a neonatal rat asphyxia model. Neonatology (2013) 0.80
Hemodynamic response to burst-suppressed and discontinuous electroencephalography activity in infants with hypoxic ischemic encephalopathy. Neurophotonics (2016) 0.79
Death associated protein kinases: molecular structure and brain injury. Int J Mol Sci (2013) 0.79
Na⁺/H⁺ exchangers and intracellular pH in perinatal brain injury. Transl Stroke Res (2014) 0.79
Neuroprotective effect of levetiracetam on hypoxic ischemic brain injury in neonatal rats. Childs Nerv Syst (2014) 0.79
Non-additive effects of delayed connexin hemichannel blockade and hypothermia after cerebral ischemia in near-term fetal sheep. J Cereb Blood Flow Metab (2015) 0.79
Neurorehabilitation after neonatal intensive care: evidence and challenges. Arch Dis Child Fetal Neonatal Ed (2015) 0.79
Immediate hypothermia reduces cardiac troponin I after hypoxic-ischemic encephalopathy in newborn pigs. Pediatr Res (2011) 0.79
The outcome of treatment limitation discussions in newborns with brain injury. Arch Dis Child Fetal Neonatal Ed (2014) 0.78
RNA-binding protein RBM3 prevents NO-induced apoptosis in human neuroblastoma cells by modulating p38 signaling and miR-143. Sci Rep (2017) 0.78
Therapeutic hypothermia for neonatal encephalopathy. Curr Treat Options Neurol (2012) 0.78
Effects of xenon and hypothermia on cerebrovascular pressure reactivity in newborn global hypoxic-ischemic pig model. J Cereb Blood Flow Metab (2013) 0.78
Protective effects of N-acetyl-L-cysteine in human oligodendrocyte progenitor cells and restoration of motor function in neonatal rats with hypoxic-ischemic encephalopathy. Evid Based Complement Alternat Med (2015) 0.78
Treatment temperature and insult severity influence the neuroprotective effects of therapeutic hypothermia. Sci Rep (2016) 0.78
The effects of therapeutic hypothermia on cerebral metabolism in neonates with hypoxic-ischemic encephalopathy: An in vivo 1H-MR spectroscopy study. J Cereb Blood Flow Metab (2015) 0.78
The Anti-Inflammatory Effects of the Small Molecule Pifithrin-µ on BV2 Microglia. Dev Neurosci (2015) 0.78
Interleukin-1 receptor blockade in perinatal brain injury. Front Pediatr (2014) 0.78
Heart Rate and Arterial Pressure Changes during Whole-Body Deep Hypothermia. ISRN Pediatr (2013) 0.78
Current controversies in newer therapies to treat birth asphyxia. Int J Pediatr (2011) 0.78
Erythropoietin as a neuroprotectant for neonatal brain injury: animal models. Methods Mol Biol (2013) 0.78
Magnetic Resonance Biomarkers in Neonatal Encephalopathy (MARBLE): a prospective multicountry study. BMJ Open (2015) 0.78
Docosahexaenoic Acid Reduces Cerebral Damage and Ameliorates Long-Term Cognitive Impairments Caused by Neonatal Hypoxia-Ischemia in Rats. Mol Neurobiol (2016) 0.78
Therapeutic hypothermia in neonatal asphyxia. Facts Views Vis Obgyn (2012) 0.77
Erythropoietin and Neonatal Neuroprotection. Clin Perinatol (2015) 0.77
Extending the duration of hypothermia does not further improve white matter protection after ischemia in term-equivalent fetal sheep. Sci Rep (2016) 0.77
Hypothermia: novel approaches for premature infants. Early Hum Dev (2011) 0.77
Pharmacokinetics of dexmedetomidine combined with therapeutic hypothermia in a piglet asphyxia model. Acta Anaesthesiol Scand (2014) 0.77
The baby cooling project of Japan to implement evidence-based neonatal cooling. Ther Hypothermia Temp Manag (2014) 0.77
Hypoxic ischaemic encephalopathy in infants. BMJ (2010) 0.77
Perinatal brain damage: The term infant. Neurobiol Dis (2015) 0.76
Barrier mechanisms in neonatal stroke. Front Neurosci (2014) 0.76
Limitations of Mild, Moderate, and Profound Hypothermia in Protecting Developing Hippocampal Neurons After Simulated Ischemia. Ther Hypothermia Temp Manag (2013) 0.76
Serial plasma metabolites following hypoxic-ischemic encephalopathy in a nonhuman primate model. Dev Neurosci (2015) 0.76
Whole-body hypothermia for neonates with hypoxic-ischemic encephalopathy. N Engl J Med (2005) 13.96
Interaction revisited: the difference between two estimates. BMJ (2003) 11.97
Selective head cooling with mild systemic hypothermia after neonatal encephalopathy: multicentre randomised trial. Lancet (2005) 11.41
Moderate hypothermia to treat perinatal asphyxial encephalopathy. N Engl J Med (2009) 7.94
No cry at birth: global estimates of intrapartum stillbirths and intrapartum-related neonatal deaths. Bull World Health Organ (2005) 4.49
Cooling for newborns with hypoxic ischaemic encephalopathy. Cochrane Database Syst Rev (2007) 3.42
Moderate hypothermia in neonatal encephalopathy: efficacy outcomes. Pediatr Neurol (2005) 3.26
Selective head cooling in newborn infants after perinatal asphyxia: a safety study. Pediatrics (1998) 2.99
Determinants of outcomes after head cooling for neonatal encephalopathy. Pediatrics (2007) 2.64
Cooling for neonatal hypoxic ischemic encephalopathy: do we have the answer? Pediatrics (2007) 2.51
Hypothermia: a neuroprotective therapy for neonatal hypoxic-ischemic encephalopathy. Pediatrics (2006) 2.07
Outcomes of safety and effectiveness in a multicenter randomized, controlled trial of whole-body hypothermia for neonatal hypoxic-ischemic encephalopathy. Pediatrics (2008) 1.89
Mild hypothermia via selective head cooling as neuroprotective therapy in term neonates with perinatal asphyxia: an experience from a single neonatal intensive care unit. J Perinatol (2006) 1.79
Hypothermia and perinatal asphyxia: executive summary of the National Institute of Child Health and Human Development workshop. J Pediatr (2006) 1.67
Whole-body hypothermia for neonatal encephalopathy: animal observations as a basis for a randomized, controlled pilot study in term infants. Pediatrics (2002) 1.66
Therapeutic hypothermia for birth asphyxia in low-resource settings: a pilot randomised controlled trial. Lancet (2008) 1.37
Neurodevelopmental outcome of infants treated with head cooling and mild hypothermia after perinatal asphyxia. Pediatrics (2001) 1.23
Hypothermia to treat neonatal hypoxic ischemic encephalopathy: systematic review. Arch Pediatr Adolesc Med (2007) 1.22
Therapeutic hypothermia in neonates. Review of current clinical data, ILCOR recommendations and suggestions for implementation in neonatal intensive care units. Resuscitation (2008) 1.20
The 'pharmacology' of neuronal rescue with cerebral hypothermia. Early Hum Dev (1998) 1.18
Selective head cooling with hypothermia suppresses the generation of platelet-activating factor in cerebrospinal fluid of newborn infants with perinatal asphyxia. Prostaglandins Leukot Essent Fatty Acids (2003) 1.14
Can the Griffiths scales predict neuromotor and perceptual-motor impairment in term infants with neonatal encephalopathy? Arch Dis Child (2004) 1.09
Hypothermia: an evolving treatment for neonatal hypoxic ischemic encephalopathy. Pediatrics (2008) 1.01
[Effects of hypothermia on cardiac function in neonates with asphyxia]. Zhonghua Er Ke Za Zhi (2003) 0.95
Selective head cooling with mild systemic hypothermia after neonatal encephalopathy: multicentre randomised trial. Lancet (2005) 11.41
Moderate hypothermia to treat perinatal asphyxial encephalopathy. N Engl J Med (2009) 7.94
Undiagnosed tuberculosis in a community with high HIV prevalence: implications for tuberculosis control. Am J Respir Crit Care Med (2006) 5.73
Donepezil and memantine for moderate-to-severe Alzheimer's disease. N Engl J Med (2012) 5.64
Evaluation of the Xpert MTB/RIF assay for the diagnosis of pulmonary tuberculosis in a high HIV prevalence setting. Am J Respir Crit Care Med (2011) 5.25
Screening for HIV-associated tuberculosis and rifampicin resistance before antiretroviral therapy using the Xpert MTB/RIF assay: a prospective study. PLoS Med (2011) 5.06
Oxygen saturation and outcomes in preterm infants. N Engl J Med (2013) 4.96
Rapid diagnosis of tuberculosis with the Xpert MTB/RIF assay in high burden countries: a cost-effectiveness analysis. PLoS Med (2011) 4.21
The dementia antipsychotic withdrawal trial (DART-AD): long-term follow-up of a randomised placebo-controlled trial. Lancet Neurol (2009) 4.17
Donepezil for the treatment of agitation in Alzheimer's disease. N Engl J Med (2007) 4.11
Effect of enhanced psychosocial care on antipsychotic use in nursing home residents with severe dementia: cluster randomised trial. BMJ (2006) 3.69
Perinatal outcomes after maternal 2009/H1N1 infection: national cohort study. BMJ (2011) 3.20
Assessment of brain tissue injury after moderate hypothermia in neonates with hypoxic-ischaemic encephalopathy: a nested substudy of a randomised controlled trial. Lancet Neurol (2009) 2.96
Differences between organophosphorus insecticides in human self-poisoning: a prospective cohort study. Lancet (2005) 2.90
Does training in obstetric emergencies improve neonatal outcome? BJOG (2006) 2.78
Determinants of outcomes after head cooling for neonatal encephalopathy. Pediatrics (2007) 2.64
Resuscitation at birth and cognition at 8 years of age: a cohort study. Lancet (2009) 2.57
Characteristics and early outcomes of patients with Xpert MTB/RIF-negative pulmonary tuberculosis diagnosed during screening before antiretroviral therapy. Clin Infect Dis (2012) 2.56
Effects of hypothermia for perinatal asphyxia on childhood outcomes. N Engl J Med (2014) 2.41
Inequalities in maternal health: national cohort study of ethnic variation in severe maternal morbidities. BMJ (2009) 2.26
Mild hypothermia and the distribution of cerebral lesions in neonates with hypoxic-ischemic encephalopathy. Pediatrics (2005) 2.26
Effect of a collector bag for measurement of postpartum blood loss after vaginal delivery: cluster randomised trial in 13 European countries. BMJ (2010) 2.25
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Hypothermia and other treatment options for neonatal encephalopathy: an executive summary of the Eunice Kennedy Shriver NICHD workshop. J Pediatr (2011) 2.22
A randomised, blinded, placebo-controlled trial in dementia patients continuing or stopping neuroleptics (the DART-AD trial). PLoS Med (2008) 2.20
Antiretrovirals for reducing the risk of mother-to-child transmission of HIV infection. Cochrane Database Syst Rev (2011) 2.07
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Multiple-dose activated charcoal in acute self-poisoning: a randomised controlled trial. Lancet (2008) 1.98
The TOBY Study. Whole body hypothermia for the treatment of perinatal asphyxial encephalopathy: a randomised controlled trial. BMC Pediatr (2008) 1.91
Donor breast milk versus infant formula for preterm infants: systematic review and meta-analysis. Arch Dis Child Fetal Neonatal Ed (2006) 1.88
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The UK Obstetric Surveillance System for rare disorders of pregnancy. BJOG (2005) 1.85
Uterine rupture by intended mode of delivery in the UK: a national case-control study. PLoS Med (2012) 1.84
Deaths due to absence of an affordable antitoxin for plant poisoning. Lancet (2003) 1.83
Culture-confirmed childhood tuberculosis in Cape Town, South Africa: a review of 596 cases. BMC Infect Dis (2007) 1.72
Hypothermia and perinatal asphyxia: executive summary of the National Institute of Child Health and Human Development workshop. J Pediatr (2006) 1.67
Improving neonatal outcome through practical shoulder dystocia training. Obstet Gynecol (2008) 1.67
Xenon enhances hypothermic neuroprotection in asphyxiated newborn pigs. Ann Neurol (2010) 1.65
Gastrostomy tube feeding in children with cerebral palsy: a prospective, longitudinal study. Dev Med Child Neurol (2005) 1.64
Surgical techniques used during caesarean section operations: results of a national survey of practice in the UK. Eur J Obstet Gynecol Reprod Biol (2002) 1.62
Molecular epidemiology of Mycobacterium tuberculosis in a South African community with high HIV prevalence. J Infect Dis (2009) 1.59
Effects of hypothermia on energy metabolism in Mammalian central nervous system. J Cereb Blood Flow Metab (2003) 1.58
A systematic review of training in acute obstetric emergencies. BJOG (2003) 1.57
Long-term cognitive outcomes of infants born moderately and late preterm. Dev Med Child Neurol (2012) 1.56
Comparison of Bayley-2 and Bayley-3 scores at 18 months in term infants following neonatal encephalopathy and therapeutic hypothermia. Dev Med Child Neurol (2013) 1.56
Randomized trial of a parenting intervention for very preterm infants: outcome at 2 years. J Pediatr (2009) 1.55
Quetiapine and rivastigmine and cognitive decline in Alzheimer's disease: randomised double blind placebo controlled trial. BMJ (2005) 1.54
NeOProM: Neonatal Oxygenation Prospective Meta-analysis Collaboration study protocol. BMC Pediatr (2011) 1.52
Gastrostomy feeding in cerebral palsy: too much of a good thing? Dev Med Child Neurol (2006) 1.51
Serum gentamicin concentrations in encephalopathic infants are not affected by therapeutic hypothermia. Pediatrics (2009) 1.51
Therapeutic hypothermia changes the prognostic value of clinical evaluation of neonatal encephalopathy. J Pediatr (2007) 1.50
Pregnancy in renal transplant recipients: a UK national cohort study. Clin J Am Soc Nephrol (2012) 1.50
Prophylactic or early selective surfactant combined with nCPAP in very preterm infants. Pediatrics (2010) 1.47
Antenatal screening and intrapartum management of Group B Streptococcus in the UK. BJOG (2004) 1.45
Patterns of brain injury in neonates exposed to perinatal sentinel events. Pediatrics (2008) 1.44
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Meconium and fetal hypoxia: some experimental observations and clinical relevance. BJOG (2002) 1.41