Published in Antimicrob Agents Chemother on February 09, 2010
Gene duplication as a mechanism of genomic adaptation to a changing environment. Proc Biol Sci (2012) 1.83
South American Plasmodium falciparum after the malaria eradication era: clonal population expansion and survival of the fittest hybrids. PLoS One (2011) 1.55
Malaria in selected non-Amazonian countries of Latin America. Acta Trop (2011) 1.53
Selective sweeps and genetic lineages of Plasmodium falciparum drug -resistant alleles in Ghana. J Infect Dis (2011) 1.26
Clonal outbreak of Plasmodium falciparum infection in eastern Panama. J Infect Dis (2014) 1.18
Malaria drug resistance: new observations and developments. Essays Biochem (2011) 1.03
Efficacy of chloroquine for the treatment of uncomplicated Plasmodium falciparum malaria in Honduras. Am J Trop Med Hyg (2013) 1.03
Historical shifts in Brazilian P. falciparum population structure and drug resistance alleles. PLoS One (2013) 1.03
Return of chloroquine-sensitive Plasmodium falciparum parasites and emergence of chloroquine-resistant Plasmodium vivax in Ethiopia. Malar J (2014) 1.02
Discordant temporal evolution of Pfcrt and Pfmdr1 genotypes and Plasmodium falciparum in vitro drug susceptibility to 4-aminoquinolines after drug policy change in French Guiana. Antimicrob Agents Chemother (2012) 1.02
Antimalarial drug resistance in Africa: key lessons for the future. Ann N Y Acad Sci (2015) 1.00
Adaptive evolution of malaria parasites in French Guiana: Reversal of chloroquine resistance by acquisition of a mutation in pfcrt. Proc Natl Acad Sci U S A (2015) 0.98
High performance of histidine-rich protein 2 based rapid diagnostic tests in French Guiana are explained by the absence of pfhrp2 gene deletion in P. falciparum. PLoS One (2013) 0.94
Evolution of the pfcrt T76 and pfmdr1 Y86 markers and chloroquine susceptibility 8 years after cessation of chloroquine use in Pikine, Senegal. Parasitol Res (2012) 0.92
Balancing drug resistance and growth rates via compensatory mutations in the Plasmodium falciparum chloroquine resistance transporter. Mol Microbiol (2015) 0.90
Molecular Epidemiology of Plasmodium falciparum Malaria Outbreak, Tumbes, Peru, 2010-2012. Emerg Infect Dis (2015) 0.90
Importation of chloroquine-resistant Plasmodium falciparum by Guatemalan peacekeepers returning from the Democratic Republic of the Congo. Malar J (2013) 0.90
Polymorphisms of molecular markers of antimalarial drug resistance and relationship with artesunate-mefloquine combination therapy in patients with uncomplicated Plasmodium falciparum malaria in Thailand. Am J Trop Med Hyg (2011) 0.87
Molecular analysis of chloroquine and sulfadoxine-pyrimethamine resistance-associated alleles in Plasmodium falciparum isolates from Nicaragua. Am J Trop Med Hyg (2014) 0.84
Gold mining areas in Suriname: reservoirs of malaria resistance? Infect Drug Resist (2014) 0.84
Distribution of drug resistance genotypes in Plasmodium falciparum in an area of limited parasite diversity in Saudi Arabia. Am J Trop Med Hyg (2012) 0.82
Analysis of polymorphisms in Plasmodium falciparum genes related to drug resistance: a survey over four decades under different treatment policies in Brazil. Malar J (2014) 0.82
Combinatorial Genetic Modeling of pfcrt-Mediated Drug Resistance Evolution in Plasmodium falciparum. Mol Biol Evol (2016) 0.81
Longitudinal analysis of Plasmodium falciparum genetic variation in Turbo, Colombia: implications for malaria control and elimination. Malar J (2015) 0.80
Genetics of chloroquine-resistant malaria: a haplotypic view. Mem Inst Oswaldo Cruz (2013) 0.78
Clonal population expansion in an outbreak of Plasmodium falciparum on the northwest coast of Ecuador. Malar J (2015) 0.77
A four-year surveillance program for detection of Plasmodium falciparum chloroquine resistance in Honduras. Mem Inst Oswaldo Cruz (2014) 0.76
Plasmodium falciparum Drug-Resistant Haplotypes and Population Structure in Postearthquake Haiti, 2010. Am J Trop Med Hyg (2016) 0.75
Pfcrt Gene in Plasmodium falciparum Field Isolates from Muzaffargarh, Pakistan. J Arthropod Borne Dis (2015) 0.75
Different patterns of pfcrt and pfmdr1 polymorphism in Plasmodium falciparum isolates from Tehama region, Yemen. PeerJ (2016) 0.75
Genetic polymorphisms in Plasmodium falciparum chloroquine resistance genes, pfcrt and pfmdr1, in North Sulawesi, Indonesia. BMC Res Notes (2017) 0.75
Molecular profile of malaria drug resistance markers of Plasmodium falciparum in Suriname. Antimicrob Agents Chemother (2017) 0.75
Arlequin (version 3.0): an integrated software package for population genetics data analysis. Evol Bioinform Online (2007) 54.21
eBURST: inferring patterns of evolutionary descent among clusters of related bacterial genotypes from multilocus sequence typing data. J Bacteriol (2004) 17.92
Evidence of artemisinin-resistant malaria in western Cambodia. N Engl J Med (2008) 17.65
Genetic diversity and chloroquine selective sweeps in Plasmodium falciparum. Nature (2002) 12.09
Mutations in the P. falciparum digestive vacuole transmembrane protein PfCRT and evidence for their role in chloroquine resistance. Mol Cell (2000) 10.72
Mefloquine resistance in Plasmodium falciparum and increased pfmdr1 gene copy number. Lancet (2004) 9.68
Microsatellite markers reveal a spectrum of population structures in the malaria parasite Plasmodium falciparum. Mol Biol Evol (2000) 7.77
Statistical analysis of real-time PCR data. BMC Bioinformatics (2006) 7.31
Reemergence of chloroquine-sensitive Plasmodium falciparum malaria after cessation of chloroquine use in Malawi. J Infect Dis (2003) 5.21
Chloroquine resistance not linked to mdr-like genes in a Plasmodium falciparum cross. Nature (1990) 5.20
pfmdr1 mutations contribute to quinine resistance and enhance mefloquine and artemisinin sensitivity in Plasmodium falciparum. Mol Microbiol (2005) 4.92
The pfmdr1 gene is associated with a multidrug-resistant phenotype in Plasmodium falciparum from the western border of Thailand. Antimicrob Agents Chemother (1999) 4.64
Several alleles of the multidrug-resistance gene are closely linked to chloroquine resistance in Plasmodium falciparum. Nature (1990) 4.61
Some comments on frequently used multiple endpoint adjustment methods in clinical trials. Stat Med (1997) 4.58
Chloroquine-resistant malaria. J Infect Dis (2001) 4.58
Pfmdr1 and in vivo resistance to artesunate-mefloquine in falciparum malaria on the Cambodian-Thai border. Am J Trop Med Hyg (2007) 4.51
Antifolate antimalarial resistance in southeast Africa: a population-based analysis. Lancet (2003) 4.26
Decreasing pfmdr1 copy number in plasmodium falciparum malaria heightens susceptibility to mefloquine, lumefantrine, halofantrine, quinine, and artemisinin. J Infect Dis (2006) 4.21
Resistance to antimalarials in Southeast Asia and genetic polymorphisms in pfmdr1. Antimicrob Agents Chemother (2003) 4.01
A selective sweep driven by pyrimethamine treatment in southeast asian malaria parasites. Mol Biol Evol (2003) 3.67
Observations on two Plasmodium falciparum infections with an abnormal response to chloroquine. Am J Trop Med Hyg (1961) 3.15
Recurrent gene amplification and soft selective sweeps during evolution of multidrug resistance in malaria parasites. Mol Biol Evol (2006) 3.01
The origins and spread of antimalarial drug resistance: lessons for policy makers. Acta Trop (2005) 2.64
Origin and dissemination of Plasmodium falciparum drug-resistance mutations in South America. J Infect Dis (2002) 2.54
Evolution of a unique Plasmodium falciparum chloroquine-resistance phenotype in association with pfcrt polymorphism in Papua New Guinea and South America. Proc Natl Acad Sci U S A (2001) 2.41
Pfmdr1 copy number and arteminisin derivatives combination therapy failure in falciparum malaria in Cambodia. Malar J (2009) 2.33
Transporters involved in resistance to antimalarial drugs. Trends Pharmacol Sci (2006) 2.09
Common origin and fixation of Plasmodium falciparum dhfr and dhps mutations associated with sulfadoxine-pyrimethamine resistance in a low-transmission area in South America. Antimicrob Agents Chemother (2007) 2.08
Selection strength and hitchhiking around two anti-malarial resistance genes. Proc Biol Sci (2005) 2.04
Decreased prevalence of the Plasmodium falciparum chloroquine resistance transporter 76T marker associated with cessation of chloroquine use against P. falciparum malaria in Hainan, People's Republic of China. Am J Trop Med Hyg (2005) 2.02
Characterization of Plasmodium falciparum isolated from the Amazon region of Brazil: evidence for quinine resistance. Am J Trop Med Hyg (1998) 1.92
pfmdr1 genotyping and in vivo mefloquine resistance on the Thai-Myanmar border. Am J Trop Med Hyg (2005) 1.76
Dynamics of malaria drug resistance patterns in the Amazon basin region following changes in Peruvian national treatment policy for uncomplicated malaria. Antimicrob Agents Chemother (2009) 1.74
Discordant patterns of genetic variation at two chloroquine resistance loci in worldwide populations of the malaria parasite Plasmodium falciparum. Antimicrob Agents Chemother (2008) 1.50
Intrahost selection of Plasmodium falciparum pfmdr1 alleles after antimalarial treatment on the northwestern border of Thailand. J Infect Dis (2006) 1.49
Decline in sulfadoxine-pyrimethamine-resistant alleles after change in drug policy in the Amazon region of Peru. Antimicrob Agents Chemother (2007) 1.43
A new method for detection of pfmdr1 mutations in Plasmodium falciparum DNA using real-time PCR. Malar J (2004) 1.36
pfcrt Polymorphism and the spread of chloroquine resistance in Plasmodium falciparum populations across the Amazon Basin. J Infect Dis (2004) 1.31
Genetics of drug-resistant Plasmodium falciparum malaria in the Venezuelan state of Bolivar. Am J Trop Med Hyg (2002) 1.21
Evidence for clonal propagation in natural isolates of Plasmodium falciparum from Venezuela. Proc Natl Acad Sci U S A (2001) 1.14
Mefloquine resistance in Plasmodium falciparum. Parasitol Today (1995) 1.04
Status of malaria eradication in the Americas. Am J Trop Med Hyg (1972) 0.94
Pfcrt and pfmdr1 alleles associated with chloroquine resistance in Plasmodium falciparum from Guyana, South America. Mem Inst Oswaldo Cruz (2004) 0.94
Drug resistance and genetic diversity of Plasmodium falciparum parasites from suriname. Am J Trop Med Hyg (2005) 0.92
[The development of resistance to pyrimethamine. Presentation of 15 cases studied in Trujillo, Venezuela]. Arch Venez Med Trop Parasitol Med (1960) 0.90
Venezuelan strains of Plasmodium falciparum resistant to sulfa and pyrimethamine as demonstrated by in vitro test. Rev Latinoam Microbiol (1979) 0.85
Chemotherapy of malaria and resistance to antimalarial drugs in Guayana area, Venezuela. Am J Trop Med Hyg (1999) 0.81
Lack of multiple copies of pfmdr1 gene in Papua New Guinea. Trans R Soc Trop Med Hyg (2008) 0.80
[Demonstration of chloroquine diphosphate resistance in Plasmodium falciparum strains naturally infecting man in an area of the Bolivar State, Venezuela]. Rev Inst Med Trop Sao Paulo (1975) 0.78
Comparative genomics of the neglected human malaria parasite Plasmodium vivax. Nature (2008) 5.96
Protective effects of the sickle cell gene against malaria morbidity and mortality. Lancet (2002) 4.13
Ensuring quality and access for malaria diagnosis: how can it be achieved? Nat Rev Microbiol (2006) 3.80
A large proportion of P. falciparum isolates in the Amazon region of Peru lack pfhrp2 and pfhrp3: implications for malaria rapid diagnostic tests. PLoS One (2010) 3.50
The heat stability of Plasmodium lactate dehydrogenase-based and histidine-rich protein 2-based malaria rapid diagnostic tests. Trans R Soc Trop Med Hyg (2007) 3.43
Ensuring quality and access for malaria diagnosis: how can it be achieved? Nat Rev Microbiol (2006) 3.42
Two nonrecombining sympatric forms of the human malaria parasite Plasmodium ovale occur globally. J Infect Dis (2010) 3.21
Effect of malaria rapid diagnostic tests on the management of uncomplicated malaria with artemether-lumefantrine in Kenya: a cluster randomized trial. Am J Trop Med Hyg (2009) 3.17
The burden of co-infection with human immunodeficiency virus type 1 and malaria in pregnant women in sub-saharan Africa. Am J Trop Med Hyg (2004) 3.00
A new NOS2 promoter polymorphism associated with increased nitric oxide production and protection from severe malaria in Tanzanian and Kenyan children. Lancet (2002) 2.69
Burden of malaria during pregnancy in areas of stable and unstable transmission in Ethiopia during a nonepidemic year. J Infect Dis (2003) 2.62
On the diversity of malaria parasites in African apes and the origin of Plasmodium falciparum from Bonobos. PLoS Pathog (2010) 2.60
Phenotypic variation of Plasmodium falciparum merozoite proteins directs receptor targeting for invasion of human erythrocytes. EMBO J (2003) 2.56
Evolution of human-chimpanzee differences in malaria susceptibility: relationship to human genetic loss of N-glycolylneuraminic acid. Proc Natl Acad Sci U S A (2005) 2.53
The malaria parasite Plasmodium vivax exhibits greater genetic diversity than Plasmodium falciparum. Nat Genet (2012) 2.43
Evidence for transmission of Plasmodium vivax among a duffy antigen negative population in Western Kenya. Am J Trop Med Hyg (2006) 2.31
World Antimalarial Resistance Network (WARN) III: molecular markers for drug resistant malaria. Malar J (2007) 2.30
Antifolate resistance in Plasmodium falciparum: multiple origins and identification of novel dhfr alleles. J Infect Dis (2006) 2.26
Common origin and fixation of Plasmodium falciparum dhfr and dhps mutations associated with sulfadoxine-pyrimethamine resistance in a low-transmission area in South America. Antimicrob Agents Chemother (2007) 2.08
Plasmodium falciparum isolates in India exhibit a progressive increase in mutations associated with sulfadoxine-pyrimethamine resistance. Antimicrob Agents Chemother (2004) 2.04
Real-time fluorescence loop mediated isothermal amplification for the diagnosis of malaria. PLoS One (2010) 2.02
The genetic diversity of Plasmodium vivax populations. Trends Parasitol (2003) 2.01
Plasma IP-10, apoptotic and angiogenic factors associated with fatal cerebral malaria in India. Malar J (2008) 2.00
Plasmodium vivax: who cares? Malar J (2008) 1.98
Cerebrospinal fluid and serum biomarkers of cerebral malaria mortality in Ghanaian children. Malar J (2007) 1.97
Origin and evolution of sulfadoxine resistant Plasmodium falciparum. PLoS Pathog (2010) 1.96
Extreme polymorphism in a vaccine antigen and risk of clinical malaria: implications for vaccine development. Sci Transl Med (2009) 1.95
Extensive microsatellite diversity in the human malaria parasite Plasmodium vivax. Gene (2008) 1.89
Diversity and evolution of the envelope gene of dengue virus type 1. Virology (2002) 1.80
Assessing the effect of natural selection in malaria parasites. Trends Parasitol (2004) 1.78
The role of animal models for research on severe malaria. PLoS Pathog (2012) 1.76
Performance of malaria rapid diagnostic tests as part of routine malaria case management in Kenya. Am J Trop Med Hyg (2009) 1.76
Dynamics of malaria drug resistance patterns in the Amazon basin region following changes in Peruvian national treatment policy for uncomplicated malaria. Antimicrob Agents Chemother (2009) 1.74
Evaluation of a malaria rapid diagnostic test for assessing the burden of malaria during pregnancy. Am J Trop Med Hyg (2004) 1.74
Whole-genome sequencing and microarray analysis of ex vivo Plasmodium vivax reveal selective pressure on putative drug resistance genes. Proc Natl Acad Sci U S A (2010) 1.74
Modulation of immune responses during HIV-malaria co-infection in pregnancy. Trends Parasitol (2005) 1.67
Plasmodium falciparum accompanied the human expansion out of Africa. Curr Biol (2010) 1.65
Single-nucleotide polymorphisms and genome diversity in Plasmodium vivax. Proc Natl Acad Sci U S A (2003) 1.62
The origin and age of Plasmodium vivax. Trends Parasitol (2006) 1.62
Pyrosequencing, a high-throughput method for detecting single nucleotide polymorphisms in the dihydrofolate reductase and dihydropteroate synthetase genes of Plasmodium falciparum. J Clin Microbiol (2006) 1.61
Evolution of modern birds revealed by mitogenomics: timing the radiation and origin of major orders. Mol Biol Evol (2011) 1.55
South American Plasmodium falciparum after the malaria eradication era: clonal population expansion and survival of the fittest hybrids. PLoS One (2011) 1.55
Malaria in selected non-Amazonian countries of Latin America. Acta Trop (2011) 1.53
HIV impairs opsonic phagocytic clearance of pregnancy-associated malaria parasites. PLoS Med (2007) 1.49
Plasmodium cynomolgi genome sequences provide insight into Plasmodium vivax and the monkey malaria clade. Nat Genet (2012) 1.49
High antibody titer against apical membrane antigen-1 is required to protect against malaria in the Aotus model. PLoS One (2009) 1.48
Protection induced by Plasmodium falciparum MSP1(42) is strain-specific, antigen and adjuvant dependent, and correlates with antibody responses. PLoS One (2008) 1.47
Progressive increase in point mutations associated with chloroquine resistance in Plasmodium falciparum isolates from India. J Infect Dis (2006) 1.45
Decline in sulfadoxine-pyrimethamine-resistant alleles after change in drug policy in the Amazon region of Peru. Antimicrob Agents Chemother (2007) 1.43
Burden of malaria in pregnancy in Jharkhand State, India. Malar J (2009) 1.36
A conserved multi-gene family induces cross-reactive antibodies effective in defense against Plasmodium falciparum. PLoS One (2009) 1.34
Hitchhiking and selective sweeps of Plasmodium falciparum sulfadoxine and pyrimethamine resistance alleles in a population from central Africa. Antimicrob Agents Chemother (2008) 1.34
Dramatic difference in diversity between Plasmodium falciparum and Plasmodium vivax reticulocyte binding-like genes. Am J Trop Med Hyg (2005) 1.33
Applied genomics: data mining reveals species-specific malaria diagnostic targets more sensitive than 18S rRNA. J Clin Microbiol (2011) 1.32
A systems-based analysis of Plasmodium vivax lifecycle transcription from human to mosquito. PLoS Negl Trop Dis (2010) 1.31
Vector bionomics and malaria transmission in the Upper Orinoco River, Southern Venezuela. Mem Inst Oswaldo Cruz (2007) 1.30
Burden of cerebral malaria in central India (2004-2007). Am J Trop Med Hyg (2008) 1.29
Monkey malaria kills four humans. Trends Parasitol (2009) 1.27
Selective sweeps and genetic lineages of Plasmodium falciparum drug -resistant alleles in Ghana. J Infect Dis (2011) 1.26
Treatment of uncomplicated multidrug-resistant falciparum malaria with artesunate-atovaquone-proguanil. Clin Infect Dis (2002) 1.25
The spatial and temporal patterns of falciparum and vivax malaria in Perú: 1994-2006. Malar J (2009) 1.25
Local population structure of Plasmodium: impact on malaria control and elimination. Malar J (2012) 1.23
Genetic diversity of vaccine candidate antigens in Plasmodium falciparum isolates from the Amazon basin of Peru. Malar J (2008) 1.23
Evaluation of three PCR-based diagnostic assays for detecting mixed Plasmodium infection. BMC Res Notes (2010) 1.23
Immunity to placental malaria. IV. Placental malaria is associated with up-regulation of macrophage migration inhibitory factor in intervillous blood. J Infect Dis (2002) 1.22
Fatal malaria infection in travelers: novel immunohistochemical assays for the detection of Plasmodium falciparum in tissues and implications for pathogenesis. Am J Trop Med Hyg (2007) 1.20