Published in J Biol Chem on February 09, 2010
The response to heat shock and oxidative stress in Saccharomyces cerevisiae. Genetics (2011) 2.16
Whole adult organism transcriptional profiling of acute metal exposures in male zebrafish. BMC Pharmacol Toxicol (2014) 1.13
Genetic and biochemical analysis of high iron toxicity in yeast: iron toxicity is due to the accumulation of cytosolic iron and occurs under both aerobic and anaerobic conditions. J Biol Chem (2010) 1.07
Loss of vacuolar H+-ATPase (V-ATPase) activity in yeast generates an iron deprivation signal that is moderated by induction of the peroxiredoxin TSA2. J Biol Chem (2013) 0.91
Rice ASR1 protein with reactive oxygen species scavenging and chaperone-like activities enhances acquired tolerance to abiotic stresses in Saccharomyces cerevisiae. Mol Cells (2012) 0.91
Structural snapshots of yeast alkyl hydroperoxide reductase Ahp1 peroxiredoxin reveal a novel two-cysteine mechanism of electron transfer to eliminate reactive oxygen species. J Biol Chem (2012) 0.85
Functional analysis of atfA gene to stress response in pathogenic thermal dimorphic fungus Penicillium marneffei. PLoS One (2014) 0.81
A Network of Paralogous Stress Response Transcription Factors in the Human Pathogen Candida glabrata. Front Microbiol (2016) 0.79
Anti-amyloidogenic properties of some phenolic compounds. Biomolecules (2015) 0.78
Tolerance of pentose utilising yeast to hydrogen peroxide-induced oxidative stress. BMC Res Notes (2014) 0.77
Sulfur transfer and activation by ubiquitin-like modifier system Uba4•Urm1 link protein urmylation and tRNA thiolation in yeast. Microb Cell (2016) 0.75
Comparative Ploidy Proteomics of Candida albicans Biofilms Unraveled the Role of the AHP1 Gene in the Biofilm Persistence Against Amphotericin B. Mol Cell Proteomics (2016) 0.75
Identification of [CuCl(acac)(tmed)], a copper(II) complex with mixed ligands, as a modulator of Cu,Zn superoxide dismutase (Sod1p) activity in yeast. J Biol Inorg Chem (2012) 0.75
Global analysis of protein expression in yeast. Nature (2003) 34.15
The retinoblastoma protein associates with the protein phosphatase type 1 catalytic subunit. Genes Dev (1993) 17.09
Metals, toxicity and oxidative stress. Curr Med Chem (2005) 7.48
Activation of the OxyR transcription factor by reversible disulfide bond formation. Science (1998) 7.16
Peroxiredoxin evolution and the regulation of hydrogen peroxide signaling. Science (2003) 6.96
In vivo cross-linking and immunoprecipitation for studying dynamic Protein:DNA associations in a chromatin environment. Methods (1999) 6.76
A thiol peroxidase is an H2O2 receptor and redox-transducer in gene activation. Cell (2002) 3.94
Regulation of the OxyR transcription factor by hydrogen peroxide and the cellular thiol-disulfide status. Proc Natl Acad Sci U S A (1999) 3.60
Yap, a novel family of eight bZIP proteins in Saccharomyces cerevisiae with distinct biological functions. Mol Cell Biol (1997) 3.55
OxyR: a molecular code for redox-related signaling. Cell (2002) 2.83
Distinct physiological functions of thiol peroxidase isoenzymes in Saccharomyces cerevisiae. J Biol Chem (2000) 1.78
A new antioxidant with alkyl hydroperoxide defense properties in yeast. J Biol Chem (1999) 1.50
Oxidation of a eukaryotic 2-Cys peroxiredoxin is a molecular switch controlling the transcriptional response to increasing levels of hydrogen peroxide. J Biol Chem (2005) 1.47
Activation of the redox sensor Pap1 by hydrogen peroxide requires modulation of the intracellular oxidant concentration. Mol Microbiol (2004) 1.42
Rck1 and Rck2 MAPKAP kinases and the HOG pathway are required for oxidative stress resistance. Mol Microbiol (2004) 1.35
Ybp1 is required for the hydrogen peroxide-induced oxidation of the Yap1 transcription factor. J Biol Chem (2003) 1.28
Peroxiredoxin-null yeast cells are hypersensitive to oxidative stress and are genomically unstable. J Biol Chem (2004) 1.23
Discrimination between paralogs using microarray analysis: application to the Yap1p and Yap2p transcriptional networks. Mol Biol Cell (2002) 1.20
Multistep disulfide bond formation in Yap1 is required for sensing and transduction of H2O2 stress signal. Mol Cell (2007) 1.09
Peroxiredoxin-mediated redox regulation of the nuclear localization of Yap1, a transcription factor in budding yeast. Antioxid Redox Signal (2005) 1.08
GPX2, encoding a phospholipid hydroperoxide glutathione peroxidase homologue, codes for an atypical 2-Cys peroxiredoxin in Saccharomyces cerevisiae. J Biol Chem (2005) 1.05
A major peroxiredoxin-induced activation of Yap1 transcription factor is mediated by reduction-sensitive disulfide bonds and reveals a low level of transcriptional activation. J Biol Chem (2008) 1.05
Genetic dissection of the phospholipid hydroperoxidase activity of yeast gpx3 reveals its functional importance. J Biol Chem (2004) 0.94
The S. cerevisiae Yap1 and Yap2 transcription factors share a common cadmium-sensing domain. FEBS Lett (2006) 0.81
Gpx1 is a stationary phase-specific thioredoxin peroxidase in fission yeast. Biochem Biophys Res Commun (2007) 0.80
Hsp90 inhibitors suppress HCV replication in replicon cells and humanized liver mice. Biochem Biophys Res Commun (2006) 1.38
Negative autoregulation of BCL-6 is bypassed by genetic alterations in diffuse large B cell lymphomas. Proc Natl Acad Sci U S A (2002) 1.30
Receptor (CD155)-dependent endocytosis of poliovirus and retrograde axonal transport of the endosome. J Virol (2004) 1.20
BCL-6 negatively regulates expression of the NF-kappaB1 p105/p50 subunit. J Immunol (2005) 1.16
Multistep disulfide bond formation in Yap1 is required for sensing and transduction of H2O2 stress signal. Mol Cell (2007) 1.09
Peroxiredoxin-mediated redox regulation of the nuclear localization of Yap1, a transcription factor in budding yeast. Antioxid Redox Signal (2005) 1.08
A major peroxiredoxin-induced activation of Yap1 transcription factor is mediated by reduction-sensitive disulfide bonds and reveals a low level of transcriptional activation. J Biol Chem (2008) 1.05
A novel fluorescent sensor protein for visualization of redox states in the cytoplasm and in peroxisomes. Mol Cell Biol (2010) 1.04
Activity of the Yap1 transcription factor in Saccharomyces cerevisiae is modulated by methylglyoxal, a metabolite derived from glycolysis. Mol Cell Biol (2004) 0.95
Potential effect on cellular response to cadmium of a single-nucleotide A --> G polymorphism in the promoter of the human gene for metallothionein IIA. Hum Genet (2006) 0.89
A ubiquitin-proteasome system is responsible for the protection of yeast and human cells against methylmercury. FASEB J (2002) 0.88
Overexpression of Ssl2p confers resistance to adriamycin and actinomycin D in Saccharomyces cerevisiae. Biochem Biophys Res Commun (2004) 0.86
High-performance liquid chromatography with photodiode array detection for determination of nobiletin content in the brain and serum of mice administrated the natural compound. Anal Bioanal Chem (2011) 0.86
Potent activity of nobiletin-rich Citrus reticulata peel extract to facilitate cAMP/PKA/ERK/CREB signaling associated with learning and memory in cultured hippocampal neurons: identification of the substances responsible for the pharmacological action. J Neural Transm (Vienna) (2013) 0.86
Overexpression of the ubiquitin-conjugating enzyme Cdc34 confers resistance to methylmercury in Saccharomyces cerevisiae. Mol Pharmacol (2002) 0.85
Identification of F-box proteins that are involved in resistance to methylmercury in Saccharomyces cerevisiae. FEBS Lett (2006) 0.85
Gene expression profiling using DNA microarray analysis of the cerebellum of mice treated with methylmercury. J Toxicol Sci (2011) 0.84
The core protein of hepatitis C virus is imported into the nucleus by transport receptor Kap123p but inhibits Kap121p-dependent nuclear import of yeast AP1-like transcription factor in yeast cells. J Biol Chem (2002) 0.83
Impairment of interferon regulatory factor-3 activation by hepatitis C virus core protein basic amino acid region 1. Biochem Biophys Res Commun (2012) 0.83
Metallothionein proteins expression, copper and zinc concentrations, and lipid peroxidation level in a rodent model for amyotrophic lateral sclerosis. Toxicology (2006) 0.83
Synthesis of betulin derivatives and their protective effects against the cytotoxicity of cadmium. Bioorg Med Chem (2002) 0.83
Overexpression of Rad23 confers resistance to methylmercury in saccharomyces cerevisiae via inhibition of the degradation of ubiquitinated proteins. Mol Pharmacol (2005) 0.82
A screening for essential cell growth-related genes involved in arsenite toxicity in Saccharomyces cerevisiae. J Toxicol Sci (2011) 0.81
Endocytic Ark/Prk kinases play a critical role in adriamycin resistance in both yeast and mammalian cells. Cancer Res (2006) 0.81
FBXO6 attenuates cadmium toxicity in HEK293 cells by inhibiting ER stress and JNK activation. J Toxicol Sci (2014) 0.80
Methylmercury induces CCL2 expression through activation of NF-κB in human 1321N1 astrocytes. J Toxicol Sci (2012) 0.80
The ubiquitin-conjugating enzymes, Ubc4 and Cdc34, mediate cadmium resistance in budding yeast through different mechanisms. Life Sci (2008) 0.80
Overexpression of FAP7, MIG3, TMA19, or YLR392c confers resistance to arsenite on Saccharomyces cerevisiae. J Toxicol Sci (2010) 0.80
Metallothionein-3 is expressed in the brain and various peripheral organs of the rat. Neurosci Lett (2008) 0.79
A novel role for Bsd2 in the resistance of yeast to adriamycin. J Cell Physiol (2005) 0.78
Copper(II) protects yeast against the toxicity of cisplatin independently of the induction of metallothionein and the inhibition of platinum uptake. Biochem Biophys Res Commun (2003) 0.78
Functions of yeast helicase Ssl2p that are essential for viability are also involved in protection from the toxicity of adriamycin. Nucleic Acids Res (2004) 0.78
Requirement of peroxiredoxin on the stationary phase of yeast cell growth. J Toxicol Sci (2014) 0.78
Characterization of antioxidant protection of cultured neural progenitor cells (NPC) against methylmercury (MeHg) toxicity. J Toxicol Sci (2009) 0.78
siRNA-mediated AMPKalpha1 subunit gene PRKAA1 silencing enhances methylmercury toxicity in HEK293 cells. J Toxicol Sci (2010) 0.78
Downregulation of arginase II and renal apoptosis by inorganic mercury: overexpression of arginase II reduces its apoptosis. Arch Toxicol (2007) 0.78
Investigation of intracellular factors involved in methylmercury toxicity. Tohoku J Exp Med (2002) 0.78
Role of metallothionein as a protective factor against radiation carcinogenesis. J Toxicol Sci (2008) 0.77
Characterization of an immortalized hepatic stellate cell line established from metallothionein-null mice. J Toxicol Sci (2006) 0.77
Global chemokine expression in methylmercury-treated mice: methylmercury induces brain-specific expression of CCL3 and CCL4. J Toxicol Sci (2013) 0.77
Low dose of methylmercury (MeHg) exposure induces caspase mediated-apoptosis in cultured neural progenitor cells. J Toxicol Sci (2013) 0.77
Cisplatin-induced expression of iron-retaining genes FIT2 and FIT3 in Saccharomyces cerevisiae. J Toxicol Sci (2006) 0.77
DNA microarray analysis of transcriptional responses of yeast cells to expression of core protein of hepatitis C virus. J Toxicol Sci (2007) 0.77
Deletion of the ubiquitin-conjugating enzyme Ubc2 confers resistance to methylmercury in budding yeast by promoting Whi2 degradation. J Toxicol Sci (2013) 0.77
Overexpression of Bop3 confers resistance to methylmercury in Saccharomyces cerevisiae through interaction with other proteins such as Fkh1, Rts1, and Msn2. Biochem Biophys Res Commun (2005) 0.77
HSC90 is required for nascent hepatitis C virus core protein stability in yeast cells. FEBS Lett (2012) 0.77
siRNA-mediated inhibition of phosphatidylinositol glycan Class B (PIGB) confers resistance to methylmercury in HEK293 cells. J Toxicol Sci (2007) 0.77
Protective role of metallothionein in bone marrow injury caused by X-irradiation. J Toxicol Sci (2008) 0.77
Identification of deubiquitinating enzymes involved in methylmercury toxicity in Saccharomyces cerevisiae. J Toxicol Sci (2012) 0.76
Cisplatin upregulates Saccharomyces cerevisiae genes involved in iron homeostasis through activation of the iron insufficiency-responsive transcription factor Aft1. J Cell Physiol (2007) 0.76
siRNA-mediated silencing of the gene for heat shock transcription factor 1 causes hypersensitivity to methylmercury in HEK293 cells. J Toxicol Sci (2011) 0.76
Overexpression of CLN1, CLN2, or ERG13 increases resistance to adriamycin in Saccharomyces cerevisiae. J Toxicol Sci (2011) 0.76
Citrate enhances the protective effect of orally administered bismuth subnitrate against the nephrotoxicity of cis-diamminedichloroplatinum. Cancer Chemother Pharmacol (2003) 0.76
Rip1 enhances methylmercury toxicity through production of reactive oxygen species (ROS) in budding yeast. J Toxicol Sci (2009) 0.76
Ubiquitin-conjugating enzyme Cdc34 mediates cadmium resistance in budding yeast through ubiquitination of the transcription factor Met4. Biochem Biophys Res Commun (2007) 0.76
Overexpression of the novel F-box protein Ymr258c confers resistance to methylmercury in Saccharomyces cerevisiae. J Toxicol Sci (2009) 0.76
Dysfunctional nascent polypeptide-associated complex (NAC) activity in ribosomes enhances adriamycin toxicity in budding yeast. J Toxicol Sci (2009) 0.76
Increased production of reactive oxygen species by the vacuolar-type (H(+))-ATPase inhibitors bafilomycin A1 and concanamycin A in RAW 264 cells. J Toxicol Sci (2012) 0.76
Overexpression of Ycg1 or Ydr520c confers resistance to cadmium in Saccharomyces cerevisiae. J Toxicol Sci (2009) 0.75
[Education for six-years graduate school of pharmaceutical sciences: a case of Tohoku University]. Yakugaku Zasshi (2011) 0.75
Ubiquitin-conjugating enzyme Cdc34 mediates methylmercury resistance in Saccharomyces cerevisiae by increasing Whi2 degradation. J Toxicol Sci (2012) 0.75
Changes in the levels of low molecular weight metabolites in the mouse cerebellum following treatment with methylmercury. J Toxicol Sci (2013) 0.75
Metallothionein determination by isocratic HPLC with fluorescence derivatization. Methods Mol Biol (2002) 0.75
Silencing of the gene for homeobox protein HOXB13 by siRNA confers resistance to methylmercury on HEK293 cells. J Toxicol Sci (2010) 0.75
Metal components analysis of metallothionein-III in the brain sections of metallothionein-I and metallothionein-II null mice exposed to mercury vapor with HPLC/ICP-MS. Anal Bioanal Chem (2005) 0.75
Inhibition of F-box protein FBXO6 gene expression by RNA interference enhances cadmium toxicity in HEK293 cells. J Toxicol Sci (2011) 0.75
Adverse health effects of humidifier disinfectants in Korea: lung toxicity of polyhexamethylene guanidine phosphate. J Toxicol Sci (2016) 0.75
Fluorescence imaging of siRNA delivery by peptide nucleic acid-based probe. Anal Sci (2015) 0.75
siRNA-mediated knockdown of the melanocortin 2 receptor accessory protein 2 (MRAP2) gene confers resistance to methylmercury on HEK293 cells. J Toxicol Sci (2010) 0.75
Brain-specific induction of secretoglobin 3A1 expression in mice treated with methylmercury. J Toxicol Sci (2013) 0.75
Methylmercury induces a brain-specific increase in chemokine CCL4 expression in mice. J Toxicol Sci (2012) 0.75
DNA microarray analysis of transcriptional responses of human neuroblastoma IMR-32 cells to methylmercury. J Toxicol Sci (2006) 0.75
Knockdown of the gene for homeobox protein HOXB13 reduces toxicity of oxidative-stress inducers in HEK293 cells. J Toxicol Sci (2013) 0.75
Synthetic fluorescent probes capable of selective recognition of 3'-overhanging nucleotides for siRNA delivery imaging. Chem Commun (Camb) (2015) 0.75