1
|
Respiratory syncytial virus NS1 protein degrades STAT2 by using the Elongin-Cullin E3 ligase.
|
J Virol
|
2007
|
1.67
|
2
|
Siglec-E is up-regulated and phosphorylated following lipopolysaccharide stimulation in order to limit TLR-driven cytokine production.
|
J Immunol
|
2009
|
1.23
|
3
|
SOCS3 targets Siglec 7 for proteasomal degradation and blocks Siglec 7-mediated responses.
|
J Biol Chem
|
2006
|
1.16
|
4
|
The deubiquitinating enzyme USP17 is highly expressed in tumor biopsies, is cell cycle regulated, and is required for G1-S progression.
|
Cancer Res
|
2010
|
1.14
|
5
|
CD33 responses are blocked by SOCS3 through accelerated proteasomal-mediated turnover.
|
Blood
|
2006
|
1.12
|
6
|
Cathepsin S from both tumor and tumor-associated cells promote cancer growth and neovascularization.
|
Int J Cancer
|
2013
|
0.93
|
7
|
The deubiquitinating enzyme USP17 is essential for GTPase subcellular localization and cell motility.
|
Nat Commun
|
2011
|
0.89
|
8
|
The deubiquitinating enzyme USP17 blocks N-Ras membrane trafficking and activation but leaves K-Ras unaffected.
|
J Biol Chem
|
2010
|
0.86
|
9
|
Ubiquitination: Added complexity in Ras and Rho family GTPase function.
|
Small GTPases
|
2011
|
0.85
|
10
|
Enhanced antitumor activity of the photosensitizer meso-Tetra(N-methyl-4-pyridyl) porphine tetra tosylate through encapsulation in antibody-targeted chitosan/alginate nanoparticles.
|
Biomacromolecules
|
2013
|
0.84
|
11
|
A highly potent and specific MET therapeutic protein antagonist with both ligand-dependent and ligand-independent activity.
|
Mol Cancer Ther
|
2013
|
0.81
|
12
|
Unlocking the Doors to Patient Satisfaction in Pediatric Orthopaedics.
|
J Pediatr Orthop
|
2016
|
0.77
|