Mark J Zylka

Author PubWeight™ 46.58‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Distinct subsets of unmyelinated primary sensory fibers mediate behavioral responses to noxious thermal and mechanical stimuli. Proc Natl Acad Sci U S A 2009 3.98
2 Topoisomerase inhibitors unsilence the dormant allele of Ube3a in neurons. Nature 2011 3.19
3 Peptidergic CGRPα primary sensory neurons encode heat and itch and tonically suppress sensitivity to cold. Neuron 2013 1.95
4 Topoisomerases facilitate transcription of long genes linked to autism. Nature 2013 1.93
5 Optimizing promoters for recombinant adeno-associated virus-mediated gene expression in the peripheral and central nervous system using self-complementary vectors. Hum Gene Ther 2011 1.90
6 Molecular genetic visualization of a rare subset of unmyelinated sensory neurons that may detect gentle touch. Nat Neurosci 2007 1.78
7 Angelman syndrome: insights into genomic imprinting and neurodevelopmental phenotypes. Trends Neurosci 2011 1.72
8 Orphan G protein-coupled receptors MrgA1 and MrgC11 are distinctively activated by RF-amide-related peptides through the Galpha q/11 pathway. Proc Natl Acad Sci U S A 2002 1.67
9 Mrgprd enhances excitability in specific populations of cutaneous murine polymodal nociceptors. J Neurosci 2009 1.53
10 Fiber-coupled light-emitting diode for localized photostimulation of neurons expressing channelrhodopsin-2. J Neurosci Methods 2007 1.38
11 Mrgprd-expressing polymodal nociceptive neurons innervate most known classes of substantia gelatinosa neurons. J Neurosci 2009 1.38
12 AMP is an adenosine A1 receptor agonist. J Biol Chem 2012 1.36
13 Ecto-5'-nucleotidase (CD73) inhibits nociception by hydrolyzing AMP to adenosine in nociceptive circuits. J Neurosci 2010 1.20
14 CGRPα-expressing sensory neurons respond to stimuli that evoke sensations of pain and itch. PLoS One 2012 1.20
15 Prostatic acid phosphatase reduces thermal sensitivity and chronic pain sensitization by depleting phosphatidylinositol 4,5-bisphosphate. J Neurosci 2010 1.19
16 PAP and NT5E inhibit nociceptive neurotransmission by rapidly hydrolyzing nucleotides to adenosine. Mol Pain 2011 1.18
17 Recombinant mouse PAP has pH-dependent ectonucleotidase activity and acts through A(1)-adenosine receptors to mediate antinociception. PLoS One 2009 1.14
18 Mechanisms of compartmentalized expression of Mrg class G-protein-coupled sensory receptors. J Neurosci 2008 1.14
19 Photochemical activation of TRPA1 channels in neurons and animals. Nat Chem Biol 2013 1.09
20 Recombinant ecto-5'-nucleotidase (CD73) has long lasting antinociceptive effects that are dependent on adenosine A1 receptor activation. Mol Pain 2010 1.04
21 The F-BAR domains from srGAP1, srGAP2 and srGAP3 regulate membrane deformation differently. J Cell Sci 2012 1.00
22 Tissue-nonspecific alkaline phosphatase acts redundantly with PAP and NT5E to generate adenosine in the dorsal spinal cord. J Neurosci 2013 0.94
23 Regulator of G-protein signaling 14 (RGS14) is a selective H-Ras effector. PLoS One 2009 0.93
24 Prostatic acid phosphatase is expressed in peptidergic and nonpeptidergic nociceptive neurons of mice and rats. PLoS One 2010 0.92
25 PAPupuncture has localized and long-lasting antinociceptive effects in mouse models of acute and chronic pain. Mol Pain 2012 0.91
26 A steroid-conjugated contrast agent for magnetic resonance imaging of cell signaling. J Am Chem Soc 2005 0.90
27 Needling adenosine receptors for pain relief. Nat Neurosci 2010 0.88
28 Orally active adenosine A(1) receptor agonists with antinociceptive effects in mice. J Med Chem 2012 0.84
29 A high throughput assay to identify small molecule modulators of prostatic acid phosphatase. Curr Chem Genomics 2009 0.82
30 Secretion and N-linked glycosylation are required for prostatic acid phosphatase catalytic and antinociceptive activity. PLoS One 2012 0.80
31 Overexpression of diacylglycerol kinase η enhances Gαq-coupled G protein-coupled receptor signaling. Mol Pharmacol 2014 0.78
32 Prostatic acid phosphatase is required for the antinociceptive effects of thiamine and benfotiamine. PLoS One 2012 0.78
33 Lipid kinases as therapeutic targets for chronic pain. Pain 2015 0.76
34 Biological constraints limit the use of rapamycin-inducible FKBP12-Inp54p for depleting PIP2 in dorsal root ganglia neurons. J Negat Results Biomed 2013 0.76
35 Emerging roles for ectonucleotidases in pain-sensing neurons. Neuropsychopharmacology 2011 0.76
36 NT5E mutations and arterial calcifications. N Engl J Med 2011 0.76
37 High-throughput screen identifies cyclic nucleotide analogs that inhibit prostatic acid phosphatase. J Biomol Screen 2012 0.75