H J Edenberg

Author PubWeight™ 122.64‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Genome-wide search for genes affecting the risk for alcohol dependence. Am J Med Genet 1998 6.04
2 Eukaryotic chromosome replication. Annu Rev Genet 1975 4.09
3 Genome-wide association study of bipolar disorder in European American and African American individuals. Mol Psychiatry 2009 3.64
4 Alcoholism susceptibility loci: confirmation studies in a replicate sample and further mapping. Alcohol Clin Exp Res 2000 3.42
5 A genome screen of maximum number of drinks as an alcoholism phenotype. Am J Med Genet 2000 3.14
6 Linkage disequilibrium at the ADH2 and ADH3 loci and risk of alcoholism. Am J Hum Genet 1999 3.03
7 Alcohol and aldehyde dehydrogenase genotypes and alcoholism in Chinese men. Am J Hum Genet 1991 2.75
8 Involvement of DNA polymerase alpha in simian virus 40 DNA replication. J Biol Chem 1978 2.74
9 Singleton deletions throughout the genome increase risk of bipolar disorder. Mol Psychiatry 2008 2.50
10 Genetic variation in the CHRNA5 gene affects mRNA levels and is associated with risk for alcohol dependence. Mol Psychiatry 2008 2.49
11 Genotypes for aldehyde dehydrogenase deficiency and alcohol sensitivity. The inactive ALDH2(2) allele is dominant. J Clin Invest 1989 2.44
12 Joint multipoint linkage analysis of multivariate qualitative and quantitative traits. II. Alcoholism and event-related potentials. Am J Hum Genet 1999 2.23
13 ADH1B is associated with alcohol dependence and alcohol consumption in populations of European and African ancestry. Mol Psychiatry 2011 2.05
14 Enrichment of cis-regulatory gene expression SNPs and methylation quantitative trait loci among bipolar disorder susceptibility variants. Mol Psychiatry 2012 1.84
15 Polymorphism of ADH and ALDH genes among four ethnic groups in China and effects upon the risk for alcoholism. Alcohol Clin Exp Res 1997 1.79
16 Identifying blood biomarkers for mood disorders using convergent functional genomics. Mol Psychiatry 2008 1.78
17 A genome-wide search for genes that relate to a low level of response to alcohol. Alcohol Clin Exp Res 2001 1.72
18 Subnuclear systems for synthesis of simian virus 40 DNA in vitro. Proc Natl Acad Sci U S A 1976 1.71
19 Rapid amplification of uncharacterized transposon-tagged DNA sequences from genomic DNA. Yeast 1997 1.57
20 Towards understanding the schizophrenia code: an expanded convergent functional genomics approach. Am J Med Genet B Neuropsychiatr Genet 2007 1.55
21 Quantitative trait loci analysis of human event-related brain potentials: P3 voltage. Electroencephalogr Clin Neurophysiol 1998 1.43
22 Association of the kappa-opioid system with alcohol dependence. Mol Psychiatry 2006 1.42
23 Low frequency of the ADH2*2 allele among Atayal natives of Taiwan with alcohol use disorders. Alcohol Clin Exp Res 1994 1.38
24 Genotyping of human alcohol dehydrogenases at the ADH2 and ADH3 loci following DNA sequence amplification. Genomics 1988 1.37
25 Initial genome scan of the NIMH genetics initiative bipolar pedigrees: chromosomes 4, 7, 9, 18, 19, 20, and 21q. Am J Med Genet 1997 1.36
26 den V gene of bacteriophage T4 codes for both pyrimidine dimer-DNA glycosylase and apyrimidinic endonuclease activities. J Virol 1981 1.36
27 DNA synthesis by partially purified replicating simian virus 40 chromosomes. Nucleic Acids Res 1977 1.33
28 Inhibition of DNA replication by ultraviolet light. Biophys J 1976 1.32
29 Evidence for both a regulatory mutation and a structural mutation in a family with maple syrup urine disease. J Clin Invest 1989 1.32
30 cDNA cloning of the E1 alpha subunit of the branched-chain alpha-keto acid dehydrogenase and elucidation of a molecular basis for maple syrup urine disease. Ann N Y Acad Sci 1989 1.28
31 Pyrimidine dimers block simian virus 40 replication forks. Mol Cell Biol 1986 1.26
32 Amplitude of visual P3 event-related potential as a phenotypic marker for a predisposition to alcoholism: preliminary results from the COGA Project. Collaborative Study on the Genetics of Alcoholism. Alcohol Clin Exp Res 1998 1.22
33 Genome-wide association study of conduct disorder symptomatology. Mol Psychiatry 2010 1.22
34 A genome-wide association study of alcohol-dependence symptom counts in extended pedigrees identifies C15orf53. Mol Psychiatry 2012 1.21
35 Sp3 and Sp4 can repress transcription by competing with Sp1 for the core cis-elements on the human ADH5/FDH minimal promoter. J Biol Chem 1999 1.17
36 Alcohol and aldehyde dehydrogenase polymorphisms and alcoholism. Behav Genet 1993 1.17
37 Novobiocin inhibition of simian virus 40 DNA replication. Nature 1980 1.16
38 Initial genome screen for bipolar disorder in the NIMH genetics initiative pedigrees: chromosomes 2, 11, 13, 14, and X. Am J Med Genet 1997 1.15
39 Cloning and sequencing of cDNA encoding the complete mouse liver alcohol dehydrogenase. Proc Natl Acad Sci U S A 1985 1.13
40 Anxiety proneness linked to epistatic loci in genome scan of human personality traits. Am J Med Genet 1998 1.11
41 Phenomic, convergent functional genomic, and biomarker studies in a stress-reactive genetic animal model of bipolar disorder and co-morbid alcoholism. Am J Med Genet B Neuropsychiatr Genet 2008 1.11
42 Candidate genes, pathways and mechanisms for alcoholism: an expanded convergent functional genomics approach. Pharmacogenomics J 2006 1.11
43 Genetics of event-related brain potentials in response to a semantic priming paradigm in families with a history of alcoholism. Am J Hum Genet 2000 1.11
44 Initial genome scan of the NIMH genetics initiative bipolar pedigrees: chromosomes 1, 6, 8, 10, and 12. Am J Med Genet 1997 1.10
45 Investigation of the role of polymorphisms at the alcohol and aldehyde dehydrogenase loci in genetic predisposition to alcohol-related end-organ damage. Hepatology 1991 1.09
46 The timecourse of DNA repair replication in ultraviolet-irradiated HeLa cells. Biochim Biophys Acta 1973 1.08
47 A genome-wide screen for genes influencing conduct disorder. Mol Psychiatry 2004 1.07
48 Linkage of an alcoholism-related severity phenotype to chromosome 16. Alcohol Clin Exp Res 1998 1.03
49 General base catalysis in a glutamine for histidine mutant at position 51 of human liver alcohol dehydrogenase. Biochemistry 1991 1.03
50 Expression and kinetic characterization of variants of human beta 1 beta 1 alcohol dehydrogenase containing substitutions at amino acid 47. J Biol Chem 1990 1.01
51 Expression and kinetic characterization of recombinant human stomach alcohol dehydrogenase. Active-site amino acid sequence explains substrate specificity compared with liver isozymes. J Biol Chem 1995 1.00
52 Familial multiple-system tauopathy with presenile dementia is localized to chromosome 17. Am J Hum Genet 1997 0.99
53 Family-based study of the association of the dopamine D2 receptor gene (DRD2) with habitual smoking. Am J Med Genet 2000 0.98
54 Family-based genome-wide association study of frontal θ oscillations identifies potassium channel gene KCNJ6. Genes Brain Behav 2012 0.98
55 Cloning and characterization of the murine promoter for the colony-stimulating factor-1-encoding gene. Gene 1991 0.97
56 Structure of the mouse Adh-1 gene and identification of a deletion in a long alternating purine-pyrimidine sequence in the first intron of strains expressing low alcohol dehydrogenase activity. Gene 1987 0.96
57 A human Raf-responsive zinc-finger protein that binds to divergent sequences. Nucleic Acids Res 1999 0.96
58 Inhibition of simian virus 40 DNA replication by ultraviolet light. Virology 1983 0.93
59 Convergent functional genomic studies of ω-3 fatty acids in stress reactivity, bipolar disorder and alcoholism. Transl Psychiatry 2011 0.93
60 Posttranscriptional regulation of human ADH5/FDH and Myf6 gene expression by upstream AUG codons. Arch Biochem Biophys 2001 0.91
61 The human beta 3 alcohol dehydrogenase subunit differs from beta 1 by a Cys for Arg-369 substitution which decreases NAD(H) binding. Biochem Biophys Res Commun 1987 0.89
62 Nucleotide sequence of the ADH2(3) gene encoding the human alcohol dehydrogenase beta 3 subunit. Alcohol Clin Exp Res 1989 0.87
63 Extraction of transcribing SV40 chromosomes in very low salt. Nucleic Acids Res 1980 0.86
64 Complete amino acid sequence of rat liver alcohol dehydrogenase deduced from the cDNA sequence. Gene 1986 0.85
65 Suggestive evidence of a locus on chromosome 10p using the NIMH genetics initiative bipolar affective disorder pedigrees. Am J Med Genet 2000 0.84
66 Ultraviolet irradiation inhibits encapsidation of simian virus 40 chromatin. J Virol 1981 0.83
67 DNA microarray analysis of differential gene expression of 6-year-old rat neural striatal progenitor cells during early differentiation. Restor Neurol Neurosci 2001 0.83
68 Cloning and characterization of the ADH5 gene encoding human alcohol dehydrogenase 5, formaldehyde dehydrogenase. Gene 1992 0.82
69 Gene expression in a young multigene family: tissue-specific differences in the expression of the human alcohol dehydrogenase genes ADH1, ADH2, and ADH3. DNA Cell Biol 1996 0.81
70 Common biological networks underlie genetic risk for alcoholism in African- and European-American populations. Genes Brain Behav 2013 0.81
71 Summary of contributions to GAW15 Group 16: processing/normalization of expression traits. Genet Epidemiol 2007 0.80
72 Inhibition of DNA synthesis by ultraviolet light. Basic Life Sci 1975 0.80
73 Polymorphisms in the bone morphogenetic protein 2 (BMP2) gene do not affect bone mineral density in white men or women. Osteoporos Int 2006 0.79
74 Pyrimidine dimer-DNA glycosylases: studies on bacteriophage T4-infected and on uninfected Escherichia coli. Biochimie 1983 0.79
75 Association studies of ALOX5 and bone mineral density in healthy adults. Osteoporos Int 2007 0.79
76 Preirradiation of host cells does not alter blockage of simian virus 40 replication forks by pyrimidine dimers. Mutat Res 1988 0.79
77 cis-acting sequences involved in protein binding and in vitro transcription of the human alcohol dehydrogenase gene ADH2. J Biol Chem 1990 0.79
78 Preirradiation of host (monkey) cells mitigates the effects of UV upon simian virus 40 DNA replication. Mutat Res 1987 0.79
79 Introduction of pyrimidine dimers into different intracellular forms of simian virus 40. Photochem Photobiol 1983 0.78
80 Expression of the human ADH2 gene: an unusual Sp1-binding site in the promoter of a gene expressed at high levels in liver. Gene 1992 0.78
81 Tissue-specific differences in the expression of the human ADH2 alcohol dehydrogenase gene and in binding of factors to cis-acting elements in its promoter. DNA Cell Biol 1994 0.78
82 Regulation of human alcohol dehydrogenase gene ADH7: importance of an AP-1 site. DNA Cell Biol 1998 0.78
83 Tissue-specific regulatory elements in the human alcohol dehydrogenase 6 gene. DNA Cell Biol 2000 0.78
84 Altered structure of ultraviolet-irradiated DNA: evidence for unwinding. Cold Spring Harb Symp Quant Biol 1983 0.78
85 The genetics of alcoholism. Curr Opin Genet Dev 1998 0.78
86 Cell-specific function of cis-acting elements in the regulation of human alcohol dehydrogenase 5 gene expression and effect of the 5'-nontranslated region. J Biol Chem 1995 0.77
87 Structure and function of a long alternating purine-pyrimidine sequence in the mouse alcohol dehydrogenase Adh-1 gene. Arch Biochem Biophys 1995 0.77
88 Cortical-striatal gene expression in neonatal hippocampal lesion (NVHL)-amplified cocaine sensitization. Genes Brain Behav 2013 0.77
89 Function of cis-acting elements in human alcohol dehydrogenase 4 (ADH4) promoter and role of C/EBP proteins in gene expression. DNA Cell Biol 1998 0.77
90 Genome screen for platelet monoamine oxidase (MAO) activity. Am J Med Genet 1999 0.76
91 A negative regulatory element upstream from the mouse Adh-1 gene can down-regulate a heterologous promoter. Gene 1994 0.76
92 Genetics of alcoholism. Science 1998 0.76
93 Structure and expression of the rat class I alcohol dehydrogenase gene. Genomics 1989 0.75
94 Extraction and quantitative precipitation of nuclear ribonucleoprotein particles. Prep Biochem 1986 0.75
95 Characterization of human alcohol dehydrogenases containing substitutions at amino acids 47 and 51. Adv Exp Med Biol 1991 0.75
96 BlastReport: a perl script to facilitate the use of sequence databases for mapping and clustering. Biotechniques 2000 0.75
97 Cloning and sequencing of a cDNA encoding rat liver alcohol dehydrogenase. Alcohol Alcohol Suppl 1987 0.75
98 Molecular cloning of mouse alcohol dehydrogenase-B2 cDNA: nucleotide sequences of the class III ADH genes evolve slowly even for silent substitutions. DNA Seq 1992 0.75
99 Characterization of the 5'-flanking sequence of rat class I alcohol dehydrogenase gene. J Biol Chem 1994 0.75
100 A novel negative element in the promoter of the mouse alcohol dehydrogenase gene Adh-1. J Biol Chem 1993 0.75
101 Cloning and expression of a human stomach alcohol dehydrogenase isozyme. Adv Exp Med Biol 1995 0.75
102 Gene regulation of alcohol metabolizing enzymes. Alcohol Clin Exp Res 1996 0.75
103 Genetic control of liver alcohol dehydrogenase expression in inbred mice. Alcohol Alcohol Suppl 1987 0.75
104 Formation of pyrimidine dimers in Simian virus 40 chromosomes and DNA in vitro: effects of salt. Photochem Photobiol 1984 0.75
105 Structure and expression of mouse liver alcohol dehydrogenase isoenzymes. Prog Clin Biol Res 1987 0.75
106 Protein-DNA interactions in the 5' region of the mouse alcohol dehydrogenase gene Adh-1. Gene 1989 0.75